Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 4159663..4160182 Replicon chromosome
Accession NZ_CP027737
Organism Pseudomonas chlororaphis subsp. piscium strain PCL1607

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag C4K32_RS18515 Protein ID WP_097304079.1
Coordinates 4159663..4159944 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag C4K32_RS18520 Protein ID WP_124348673.1
Coordinates 4159934..4160182 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4K32_RS18495 4155551..4155787 - 237 WP_124348670.1 hypothetical protein -
C4K32_RS18500 4155807..4156982 - 1176 WP_124348671.1 S-type pyocin domain-containing protein -
C4K32_RS18505 4157308..4157790 + 483 WP_009049637.1 acyl-CoA thioesterase -
C4K32_RS18510 4157847..4159496 + 1650 WP_124348672.1 FMN-binding glutamate synthase family protein -
C4K32_RS18515 4159663..4159944 - 282 WP_097304079.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C4K32_RS18520 4159934..4160182 - 249 WP_124348673.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
C4K32_RS18525 4160279..4161067 - 789 WP_124299848.1 helix-turn-helix transcriptional regulator -
C4K32_RS18530 4161152..4162150 + 999 WP_124348674.1 bile acid:sodium symporter -
C4K32_RS18535 4162364..4164127 + 1764 WP_124348675.1 hypothetical protein -
C4K32_RS18540 4164201..4164662 + 462 WP_124348676.1 YccF domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-81)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10863.71 Da        Isoelectric Point: 10.6993

>T100094 WP_097304079.1 NZ_CP027737:c4159944-4159663 [Pseudomonas chlororaphis subsp. piscium]
MTYELEFSEKAWKEWQKLGPTLKEQFKKKLQERLVSPHVPADRLSGLGNAYKIKLRTAGYRLVYRVVDEVLVVTVIAVGK
RERGSVYQQARKR

Download         Length: 282 bp

>T100094 NZ_CP027737:c4159944-4159663 [Pseudomonas chlororaphis subsp. piscium]
ATGACTTATGAGCTGGAGTTCTCCGAGAAAGCCTGGAAGGAATGGCAAAAGCTGGGCCCCACGCTGAAAGAGCAATTCAA
GAAGAAGCTGCAGGAACGACTCGTCAGCCCCCATGTCCCGGCCGATCGCCTGAGCGGCTTGGGCAATGCCTACAAAATCA
AACTGCGCACGGCTGGCTACCGCCTGGTGTATCGGGTGGTGGATGAGGTGTTGGTGGTGACGGTCATTGCCGTGGGCAAG
CGGGAGCGGGGGAGTGTCTATCAGCAAGCCAGGAAGCGTTAG

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 8996.39 Da        Isoelectric Point: 4.5488

>AT100094 WP_124348673.1 NZ_CP027737:c4160182-4159934 [Pseudomonas chlororaphis subsp. piscium]
MTHVLLSNVVASISELKKNPMGTVAAGGGSSVAILNRNEPAFYCVPAKEYEAMMERLEDMELLALCRERENDPTIKVSLN
DL

Download         Length: 249 bp

>AT100094 NZ_CP027737:c4160182-4159934 [Pseudomonas chlororaphis subsp. piscium]
ATGACCCATGTCCTTCTGTCCAACGTCGTTGCGAGCATTTCCGAGCTCAAGAAAAACCCCATGGGCACCGTTGCTGCCGG
TGGCGGTTCCTCCGTGGCCATACTCAATCGCAACGAACCGGCGTTTTACTGCGTTCCGGCCAAGGAATACGAAGCCATGA
TGGAGCGCCTGGAGGATATGGAACTGCTCGCCTTGTGCCGTGAGCGAGAGAATGATCCGACCATCAAGGTTTCGCTCAAT
GACTTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References