Detailed information of TA system TA100078

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relE-yefM/YoeB-YefM
• Location: 4598854..4599359
• Replicon: chromosome
• Accession: NZ_CP027734
• Organism: Pseudomonas sp. R1-43-08

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: C4J87_RS21075
• Protein ID: WP_124368290.1
• Coordinates: 4599105..4599359 (+)
• Length: 85 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: -
• Locus tag: C4J87_RS21070
• Protein ID: WP_124368289.1
• Coordinates: 4598854..4599108 (+)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C4J87_RS21050	4594061..4594267	+	207	WP_124368285.1	hypothetical protein	-
C4J87_RS21055	4594381..4596273	+	1893	WP_124368286.1	alkaline phosphatase family protein	-
C4J87_RS21060	4596391..4597404	+	1014	WP_124368287.1	diguanylate cyclase	-
C4J87_RS21065	4597510..4598760	+	1251	WP_124368288.1	aspartate aminotransferase family protein	-
C4J87_RS21070	4598854..4599108	+	255	WP_124368289.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
C4J87_RS21075	4599105..4599359	+	255	WP_124368290.1	Txe/YoeB family addiction module toxin	Toxin
C4J87_RS21080	4599462..4600178	+	717	WP_124368291.1	hypothetical protein	-
C4J87_RS21085	4600188..4601309	-	1122	WP_124368292.1	aminotransferase class V-fold PLP-dependent enzyme	-
C4J87_RS21090	4601311..4602513	-	1203	WP_124368293.1	MFS transporter	-
C4J87_RS21095	4602513..4603763	-	1251	WP_124368294.1	ATP-grasp domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (5-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-73)

Sequences

Toxin

Protein

• Length: 85 a.a.
• Molecular weight: 10049.61 Da
• Isoelectric Point: 8.0381

>T100078 WP_124368290.1 NZ_CP027734:4599105-4599359 [Pseudomonas sp. R1-43-08]
MKILFTPEGWDDYLWFQQNDKAGLKRINLLIKAIQRDPFEGVGKPEPLKHNLSGYWSRRITAEHRLVYGIEEDVVQILMC
RYHY

Nucleotide

• Length: 255 bp

>T100078 NZ_CP027734:4599105-4599359 [Pseudomonas sp. R1-43-08]
ATGAAAATACTCTTTACCCCTGAGGGCTGGGACGATTATCTGTGGTTTCAACAAAACGACAAGGCAGGGCTCAAGCGTAT
AAACCTGCTCATCAAAGCGATTCAAAGAGACCCATTTGAAGGTGTTGGAAAACCTGAGCCCCTCAAACACAACCTGAGCG
GTTACTGGTCTCGGCGAATCACAGCAGAGCATCGTCTGGTGTATGGCATCGAGGAGGATGTAGTACAGATCCTCATGTGC
CGTTATCACTACTGA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9599.97 Da
• Isoelectric Point: 6.7262

>AT100078 WP_124368289.1 NZ_CP027734:4598854-4599108 [Pseudomonas sp. R1-43-08]
METINYTHARAHLSETMDRVNEDHIPLLLTRQKGEPVVMISLSEFNALEETAYLLRSPKNAERLINSVNSLRAGKAKPRQ
LIEE

Nucleotide

• Length: 255 bp

>AT100078 NZ_CP027734:4598854-4599108 [Pseudomonas sp. R1-43-08]
ATGGAAACTATCAACTACACCCATGCGCGTGCGCACCTGTCCGAAACCATGGACCGCGTTAATGAAGATCACATTCCACT
GCTCCTGACCCGACAAAAAGGCGAACCGGTGGTGATGATCTCGTTGTCAGAATTCAATGCTCTCGAGGAAACAGCCTATT
TACTGCGCTCGCCAAAAAATGCCGAACGCCTCATCAACTCAGTCAACAGCTTACGAGCCGGCAAAGCCAAGCCAAGGCAG
TTGATTGAAGAATGA