Detailed information of TA system TA100077

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 3620714..3621278
• Replicon: chromosome
• Accession: NZ_CP027734
• Organism: Pseudomonas sp. R1-43-08

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: C4J87_RS16575
• Protein ID: WP_124367664.1
• Coordinates: 3620991..3621278 (+)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: C4J87_RS16570
• Protein ID: WP_124367663.1
• Coordinates: 3620714..3621001 (+)
• Length: 96 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C4J87_RS16545	3615914..3617314	+	1401	WP_124367658.1	heavy metal sensor histidine kinase	-
C4J87_RS16550	3617327..3617773	-	447	WP_124367659.1	RcnB family protein	-
C4J87_RS16555	3617839..3618468	-	630	WP_124367660.1	pyroglutamyl-peptidase I	-
C4J87_RS16560	3618476..3619426	-	951	WP_124367661.1	DUF979 domain-containing protein	-
C4J87_RS16565	3619423..3620139	-	717	WP_124367662.1	DUF969 domain-containing protein	-
C4J87_RS16570	3620714..3621001	+	288	WP_124367663.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
C4J87_RS16575	3620991..3621278	+	288	WP_124367664.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
C4J87_RS16580	3621666..3622307	-	642	WP_124367665.1	hypothetical protein	-
C4J87_RS16585	3622413..3622832	-	420	WP_177412798.1	hypothetical protein	-
C4J87_RS16595	3623331..3624614	+	1284	WP_124367666.1	FAD-binding oxidoreductase	-
C4J87_RS16615	3625265..3626029	-	765	WP_124367667.1	SDR family oxidoreductase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (7-86)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (10-71)

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 11045.88 Da
• Isoelectric Point: 10.3662

>T100077 WP_124367664.1 NZ_CP027734:3620991-3621278 [Pseudomonas sp. R1-43-08]
MANEYNVEWDPKALKELRKLDGTVRLQFLKKLQERQTGPRVPGDALHGMKDCYKIKLRGAGYRLVYRVEDERIVILVLAV
GKRERSSVYEQAGKR

Nucleotide

• Length: 288 bp

>T100077 NZ_CP027734:3620991-3621278 [Pseudomonas sp. R1-43-08]
ATGGCCAATGAGTACAACGTCGAGTGGGATCCGAAGGCGCTGAAAGAACTGCGAAAGCTCGATGGCACAGTCCGCCTGCA
GTTCTTGAAAAAACTACAGGAACGGCAGACCGGACCGCGCGTGCCAGGTGATGCGCTTCACGGCATGAAGGATTGCTACA
AAATCAAATTGCGCGGCGCCGGCTATCGGCTGGTGTACCGCGTTGAAGATGAGCGAATTGTCATCCTGGTGTTGGCCGTC
GGTAAACGTGAGCGCAGCTCCGTGTACGAGCAGGCGGGGAAGCGATAG

Antitoxin

Protein

• Length: 96 a.a.
• Molecular weight: 10140.53 Da
• Isoelectric Point: 4.0470

>AT100077 WP_124367663.1 NZ_CP027734:3620714-3621001 [Pseudomonas sp. R1-43-08]
MQNILADVAVSVSELKKNPSSVLSGANGLPVAVLNHNRVVGYMVPANVYEAMVERLDELELVQLVKARLDANETPVQVSL
DDLIGEAEADIANGQ

Nucleotide

• Length: 288 bp

>AT100077 NZ_CP027734:3620714-3621001 [Pseudomonas sp. R1-43-08]
ATGCAAAATATCCTGGCTGATGTAGCCGTCAGCGTATCCGAACTCAAGAAGAACCCGTCCTCCGTCTTGAGCGGCGCCAA
CGGCTTGCCTGTGGCTGTGCTGAACCACAATCGCGTTGTGGGTTACATGGTCCCTGCCAACGTTTACGAAGCAATGGTCG
AACGCCTGGATGAACTGGAATTGGTCCAACTGGTAAAGGCTCGGCTCGACGCCAATGAAACACCGGTTCAAGTATCGCTC
GACGATCTCATTGGCGAGGCCGAGGCAGATATCGCCAATGGCCAATGA