100076

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 3487784..3489000 Replicon chromosome
Accession NZ_CP027734
Organism Pseudomonas sp. R1-43-08

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag C4J87_RS15925 Protein ID WP_124367567.1
Coordinates 3488428..3489000 (+) Length 191 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag C4J87_RS15920 Protein ID WP_124367566.1
Coordinates 3487784..3488341 (+) Length 186 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4J87_RS15890 3482815..3483699 - 885 WP_124367561.1 LysR family transcriptional regulator -
C4J87_RS15895 3483699..3484619 - 921 WP_124367562.1 LysR family transcriptional regulator -
C4J87_RS15900 3484636..3485268 - 633 WP_124367563.1 glutathione S-transferase -
C4J87_RS15905 3485494..3486570 + 1077 WP_124367564.1 aldo/keto reductase -
C4J87_RS15910 3486644..3486880 + 237 WP_124363466.1 hypothetical protein -
C4J87_RS15915 3486920..3487750 + 831 WP_124367565.1 acid phosphatase -
C4J87_RS15920 3487784..3488341 + 558 WP_124367566.1 helix-turn-helix domain-containing protein Antitoxin
C4J87_RS15925 3488428..3489000 + 573 WP_124367567.1 HD domain-containing protein Toxin
C4J87_RS15930 3489007..3489429 - 423 WP_124367568.1 RidA family protein -
C4J87_RS15935 3489607..3491190 - 1584 WP_124367569.1 FAD-dependent oxidoreductase -
C4J87_RS15940 3491202..3492125 - 924 WP_124367570.1 ABC transporter substrate-binding protein -
C4J87_RS15945 3492144..3492917 - 774 WP_124367571.1 amino acid ABC transporter ATP-binding protein -
C4J87_RS15950 3492910..3493881 - 972 WP_124367572.1 amino acid ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HD domain

(16-173)

Antitoxin

Cro/C1-type helix-turn-helix domain

(12-62)


Sequences

Toxin        


Download         Length: 191 a.a.        Molecular weight: 21316.35 Da        Isoelectric Point: 4.9538

>T100076 WP_124367567.1 NZ_CP027734:3488428-3489000 [Pseudomonas sp. R1-43-08]
MDFEKIKGRLDFLREAEKLKDVLRSAHTASGRTESTAEHSWRLCLMAMVFADQLPGLDLLKILKMCVIHDLGEAINGDIP
AVSQAAFPNKGEQERRDLLQLTQALDGPLKSQILTLWDDYENALSPEAKAVKAMDKLETLLQHTQGLNPPDFDYAFNLAY
GKKHTDAEPLFEALRALIDRATQERLDAAQ

Download         Length: 573 bp

>T100076 NZ_CP027734:3488428-3489000 [Pseudomonas sp. R1-43-08]
ATGGACTTCGAGAAAATCAAAGGCCGCCTCGACTTTCTGCGCGAAGCCGAGAAACTCAAGGACGTACTCAGAAGCGCCCA
CACCGCTTCGGGACGCACGGAAAGTACCGCCGAACACAGTTGGCGCCTGTGCCTGATGGCGATGGTGTTCGCCGATCAAC
TGCCCGGCCTGGACCTGCTTAAAATTCTCAAGATGTGCGTGATCCATGACTTGGGCGAAGCCATTAACGGTGACATTCCA
GCAGTCAGCCAGGCGGCGTTTCCCAACAAGGGCGAGCAGGAGCGGCGCGACCTGCTGCAGTTGACCCAAGCCCTGGATGG
GCCCCTGAAAAGCCAGATCCTGACGCTGTGGGATGATTACGAGAACGCGCTGTCGCCGGAAGCCAAAGCCGTCAAGGCAA
TGGACAAGCTGGAGACCCTGCTGCAGCACACCCAGGGCCTCAACCCGCCGGATTTCGATTACGCTTTCAACCTGGCATAC
GGCAAGAAACATACGGATGCCGAGCCCTTGTTCGAGGCGCTGCGTGCGCTGATCGACCGGGCTACCCAGGAACGCCTCGA
CGCCGCGCAGTGA

Antitoxin


Download         Length: 186 a.a.        Molecular weight: 20501.50 Da        Isoelectric Point: 10.3561

>AT100076 WP_124367566.1 NZ_CP027734:3487784-3488341 [Pseudomonas sp. R1-43-08]
MPALLPQPAIPGIALRRWRLLHRVKQTHAAQMFNVNQSTLSRWENGLQAMDAAAHQQLERLLSARLDTAADQALAGLVRD
SSRAVHLVCDLTHRLLACSPSRAAQFSRPLVDLMGQSLWRYATAEIRQVEAALDHTGWRENQAPPALQFSTGSNDSSLVP
IRPSLCRWTRLILSDGSAARLVETL

Download         Length: 558 bp

>AT100076 NZ_CP027734:3487784-3488341 [Pseudomonas sp. R1-43-08]
ATGCCCGCCCTGCTGCCCCAGCCCGCCATTCCGGGCATTGCGCTGCGCCGATGGCGCCTGTTACACCGCGTCAAGCAAAC
CCATGCCGCACAGATGTTCAACGTAAACCAATCGACGTTGTCCCGTTGGGAGAATGGCCTGCAAGCCATGGACGCTGCCG
CGCACCAACAGCTGGAACGGTTGCTGTCCGCTCGGCTTGACACCGCAGCTGATCAGGCCCTGGCTGGGCTGGTCAGAGAC
AGCTCGCGCGCCGTACACCTGGTGTGCGACCTGACGCACCGCCTCCTGGCCTGTTCGCCCTCCCGCGCCGCTCAGTTCAG
CCGCCCGTTGGTCGACTTGATGGGCCAATCGCTGTGGCGTTATGCGACAGCGGAAATCCGCCAGGTCGAAGCGGCGTTGG
ATCACACCGGCTGGCGCGAGAACCAGGCGCCGCCGGCGCTTCAATTCAGCACCGGCAGCAACGACTCCAGCCTCGTGCCG
ATCCGCCCGAGCCTGTGTCGCTGGACACGCCTGATCCTCAGCGATGGCAGCGCCGCGCGTCTGGTCGAGACGCTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References