Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-YefM
Location 4822042..4822547 Replicon chromosome
Accession NZ_CP027733
Organism Pseudomonas sp. R4-39-08

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag C4J88_RS22285 Protein ID WP_124408130.1
Coordinates 4822293..4822547 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag C4J88_RS22280 Protein ID WP_124368289.1
Coordinates 4822042..4822296 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4J88_RS22260 4817250..4817456 + 207 WP_124408127.1 hypothetical protein -
C4J88_RS22265 4817570..4819461 + 1892 Protein_4312 alkaline phosphatase family protein -
C4J88_RS22270 4819579..4820592 + 1014 WP_124408128.1 diguanylate cyclase -
C4J88_RS22275 4820698..4821948 + 1251 WP_124408129.1 aspartate aminotransferase family protein -
C4J88_RS22280 4822042..4822296 + 255 WP_124368289.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
C4J88_RS22285 4822293..4822547 + 255 WP_124408130.1 Txe/YoeB family addiction module toxin Toxin
C4J88_RS22290 4822650..4823366 + 717 WP_124408131.1 hypothetical protein -
C4J88_RS22295 4823376..4824497 - 1122 WP_124408132.1 aminotransferase class V-fold PLP-dependent enzyme -
C4J88_RS22300 4824499..4825701 - 1203 WP_124408133.1 MFS transporter -
C4J88_RS22305 4825701..4826951 - 1251 WP_124408134.1 ATP-grasp domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10079.60 Da        Isoelectric Point: 7.2746

>T100069 WP_124408130.1 NZ_CP027733:4822293-4822547 [Pseudomonas sp. R4-39-08]
MKILFTPEGWDDYLWFQQNDKAGLKRINLLIKAIQRDPFEGVGKPEPLKHNLSGYWSRRITAEHRLVYGIEEDEVQILMC
RYHY

Download         Length: 255 bp

>T100069 NZ_CP027733:4822293-4822547 [Pseudomonas sp. R4-39-08]
ATGAAAATACTCTTTACCCCTGAGGGCTGGGACGATTATCTCTGGTTTCAACAAAACGACAAGGCAGGGCTCAAGCGTAT
AAACCTGCTCATCAAAGCGATTCAAAGAGACCCATTTGAAGGTGTTGGAAAACCTGAGCCCCTCAAACACAACCTGAGCG
GCTACTGGTCTCGGCGAATCACAGCAGAGCATCGTCTGGTGTATGGCATCGAGGAGGATGAAGTACAGATCCTCATGTGC
CGTTATCACTACTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9599.97 Da        Isoelectric Point: 6.7262

>AT100069 WP_124368289.1 NZ_CP027733:4822042-4822296 [Pseudomonas sp. R4-39-08]
METINYTHARAHLSETMDRVNEDHIPLLLTRQKGEPVVMISLSEFNALEETAYLLRSPKNAERLINSVNSLRAGKAKPRQ
LIEE

Download         Length: 255 bp

>AT100069 NZ_CP027733:4822042-4822296 [Pseudomonas sp. R4-39-08]
ATGGAAACTATCAACTACACCCATGCGCGTGCGCACCTGTCCGAAACCATGGACCGCGTTAATGAAGATCACATTCCACT
GCTCCTGACCCGACAAAAAGGCGAACCGGTGGTGATGATCTCGTTGTCAGAATTCAATGCTCTCGAGGAAACAGCCTATT
TACTGCGCTCGCCAAAAAATGCCGAACGCCTCATCAACTCAGTCAACAGCTTACGAGCCGGCAAAGCCAAGCCAAGGCAG
TTGATTGAAGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References