100068

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 4465950..4466578 Replicon chromosome
Accession NZ_CP027733
Organism Pseudomonas sp. R4-39-08

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag C4J88_RS20570 Protein ID WP_124407973.1
Coordinates 4465950..4466348 (-) Length 133 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag C4J88_RS20575 Protein ID WP_124407974.1
Coordinates 4466348..4466578 (-) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4J88_RS20550 4461574..4463391 - 1818 WP_124407970.1 hypothetical protein -
C4J88_RS20555 4463744..4464322 + 579 WP_124407971.1 Bro-N domain-containing protein -
C4J88_RS20560 4464422..4465138 + 717 WP_124407972.1 HNH endonuclease -
C4J88_RS20565 4465212..4465859 + 648 WP_124365199.1 HAD-IB family hydrolase -
C4J88_RS20570 4465950..4466348 - 399 WP_124407973.1 tRNA(fMet)-specific endonuclease VapC Toxin
C4J88_RS20575 4466348..4466578 - 231 WP_124407974.1 antitoxin Antitoxin
C4J88_RS20580 4466770..4467717 + 948 WP_124407975.1 hypothetical protein -
C4J88_RS20585 4467827..4468207 + 381 WP_124407976.1 helix-turn-helix domain-containing protein -
C4J88_RS20590 4468261..4469733 - 1473 WP_124408662.1 peptide amidase -
C4J88_RS20595 4469932..4470669 - 738 WP_177412924.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 15010.26 Da        Isoelectric Point: 8.0459

>T100068 WP_124407973.1 NZ_CP027733:c4466348-4465950 [Pseudomonas sp. R4-39-08]
MLKFMLDTNICIFTIKNRPQQVRETFKKHYGQLAISTVTLMELIYGAEKSSNPERNLADIEGFAARLEVLKYDQDAAMHT
GQLRAELARAGTPIGPYDQMIAGHARSQGLIMVTNNRREFDRVPGLRVEDWV

Download         Length: 399 bp

>T100068 NZ_CP027733:c4466348-4465950 [Pseudomonas sp. R4-39-08]
ATGCTCAAGTTCATGCTCGATACCAACATCTGCATCTTTACCATCAAAAACAGACCCCAGCAGGTGCGCGAAACATTCAA
AAAGCACTATGGCCAATTGGCCATTAGTACAGTGACCCTGATGGAGCTGATTTACGGTGCGGAAAAATCATCCAACCCAG
AGCGAAACCTGGCCGATATCGAAGGCTTTGCAGCACGTCTGGAAGTCCTGAAATACGACCAGGATGCCGCCATGCACACA
GGCCAGCTTCGCGCAGAGCTGGCGAGAGCAGGTACTCCGATAGGGCCATATGACCAGATGATCGCTGGGCATGCGCGTTC
GCAGGGCCTGATTATGGTCACTAACAACCGGCGCGAGTTCGACCGTGTGCCAGGTTTGCGGGTAGAGGATTGGGTATAA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8481.31 Da        Isoelectric Point: 4.2545

>AT100068 WP_124407974.1 NZ_CP027733:c4466578-4466348 [Pseudomonas sp. R4-39-08]
MDQGSVFQSNRSQAVRLPKAAALPDDVKRVDVVSIGRARIITPAGESWDSWFDGEGVTPDFMNDREQPADQERESF

Download         Length: 231 bp

>AT100068 NZ_CP027733:c4466578-4466348 [Pseudomonas sp. R4-39-08]
ATGGACCAAGGTTCTGTATTCCAAAGTAACCGCAGCCAAGCTGTGCGTTTGCCAAAGGCCGCTGCACTACCGGATGACGT
AAAACGTGTAGATGTTGTCTCAATTGGCAGAGCACGAATCATCACTCCGGCTGGTGAGTCATGGGACAGCTGGTTTGATG
GAGAGGGCGTCACGCCGGACTTCATGAACGACCGCGAGCAGCCTGCTGACCAAGAGCGGGAATCTTTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References