100067

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 3745763..3746979 Replicon chromosome
Accession NZ_CP027733
Organism Pseudomonas sp. R4-39-08

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag C4J88_RS17280 Protein ID WP_124407655.1
Coordinates 3746407..3746979 (+) Length 191 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag C4J88_RS17275 Protein ID WP_124407654.1
Coordinates 3745763..3746320 (+) Length 186 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4J88_RS17245 3740794..3741678 - 885 WP_124407650.1 LysR family transcriptional regulator -
C4J88_RS17250 3741678..3742598 - 921 WP_124407651.1 LysR family transcriptional regulator -
C4J88_RS17255 3742615..3743247 - 633 WP_124407652.1 glutathione S-transferase -
C4J88_RS17260 3743473..3744549 + 1077 WP_124371208.1 aldo/keto reductase -
C4J88_RS17265 3744623..3744859 + 237 WP_124363466.1 hypothetical protein -
C4J88_RS17270 3744899..3745729 + 831 WP_124407653.1 acid phosphatase -
C4J88_RS17275 3745763..3746320 + 558 WP_124407654.1 helix-turn-helix domain-containing protein Antitoxin
C4J88_RS17280 3746407..3746979 + 573 WP_124407655.1 HD domain-containing protein Toxin
C4J88_RS17285 3746986..3747408 - 423 WP_124407656.1 RidA family protein -
C4J88_RS17290 3747586..3749169 - 1584 WP_124407657.1 FAD-dependent oxidoreductase -
C4J88_RS17295 3749181..3750104 - 924 WP_124407658.1 ABC transporter substrate-binding protein -
C4J88_RS17300 3750123..3750896 - 774 WP_124407659.1 amino acid ABC transporter ATP-binding protein -
C4J88_RS17305 3750889..3751860 - 972 WP_124367572.1 amino acid ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HD domain

(16-173)

Antitoxin

Cro/C1-type helix-turn-helix domain

(12-62)


Sequences

Toxin        


Download         Length: 191 a.a.        Molecular weight: 21344.40 Da        Isoelectric Point: 4.9538

>T100067 WP_124407655.1 NZ_CP027733:3746407-3746979 [Pseudomonas sp. R4-39-08]
MDFEKIKGRLDFLREAEKLKDVLRSAHTASGRTESTAEHSWRLCLMAMVFADQLPGLDLLKILKMCVIHDLGEAINGDIP
AVSQAAFPNKGEQERRDLLQLTQALDGPLKSQILTLWDDYENALSPEAKAVKAMDKLETLLQHTQGLNPPDFDYAFNLVY
GKKHTDAEPLFEALRALIDRATQERLDAAQ

Download         Length: 573 bp

>T100067 NZ_CP027733:3746407-3746979 [Pseudomonas sp. R4-39-08]
ATGGACTTCGAGAAAATCAAAGGCCGCCTCGACTTTCTGCGCGAAGCCGAGAAACTCAAGGACGTGCTCAGAAGCGCCCA
CACCGCTTCGGGACGCACGGAAAGTACCGCCGAACACAGTTGGCGCCTGTGCCTGATGGCGATGGTGTTCGCCGATCAAC
TGCCCGGCCTGGACCTGCTTAAAATCCTCAAGATGTGCGTGATCCATGACTTGGGCGAAGCCATTAACGGTGACATTCCA
GCAGTCAGCCAGGCGGCGTTTCCCAACAAGGGCGAGCAGGAGCGGCGCGACCTGCTGCAGTTGACCCAAGCCCTGGATGG
GCCCCTGAAAAGCCAGATTCTGACGCTGTGGGATGACTACGAGAACGCACTGTCGCCGGAAGCCAAAGCCGTCAAGGCGA
TGGACAAGCTGGAGACCCTGCTGCAGCACACCCAGGGCCTCAACCCGCCGGATTTCGATTACGCTTTCAACCTGGTATAC
GGCAAGAAACATACGGATGCCGAGCCCTTATTCGAGGCGCTACGTGCGTTGATCGACCGGGCTACCCAGGAACGCCTCGA
CGCCGCGCAGTGA

Antitoxin


Download         Length: 186 a.a.        Molecular weight: 20517.54 Da        Isoelectric Point: 10.3561

>AT100067 WP_124407654.1 NZ_CP027733:3745763-3746320 [Pseudomonas sp. R4-39-08]
MPALLLQPAIPGIALRRWRLLHRVKQTHAAQMFNVNQSTLSRWENGLQAMDAAAHQQLERLLSARLDTAADQALAGLVRD
SSRAVHLVCDLTHRLLACSPSRAAQFSRPLVDLMGQSLWRYATAEIRQVEAALDHTGWRENQAPPALQFSTGSNDSSLVP
IRPSLCRWTRLILSDGSAARLVETL

Download         Length: 558 bp

>AT100067 NZ_CP027733:3745763-3746320 [Pseudomonas sp. R4-39-08]
ATGCCCGCCCTGCTGCTCCAGCCCGCCATTCCGGGCATTGCGCTGCGCCGATGGCGCCTGTTACACCGCGTCAAGCAAAC
CCATGCCGCACAGATGTTCAACGTAAATCAATCGACGTTGTCCCGCTGGGAGAATGGCCTGCAAGCCATGGACGCTGCCG
CGCACCAACAGCTGGAACGGTTGCTGTCCGCTCGGCTTGACACCGCAGCTGATCAGGCCCTGGCCGGGCTGGTCAGAGAC
AGCTCGCGCGCCGTACACCTGGTGTGCGACCTGACGCACCGCCTCCTGGCCTGTTCGCCCTCCCGCGCCGCCCAGTTCAG
CCGCCCATTGGTCGACTTGATGGGCCAATCGCTGTGGCGTTATGCGACAGCGGAAATCCGCCAGGTCGAAGCCGCGTTGG
ACCACACCGGCTGGCGCGAGAACCAGGCGCCGCCAGCGCTTCAATTCAGCACCGGCAGCAACGACTCCAGCCTCGTGCCG
ATCCGCCCAAGCCTGTGTCGCTGGACACGCCTGATCCTCAGCGATGGCAGCGCCGCGCGTCTGGTCGAGACGCTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References