Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parE_1-relB/RelE(toxin)
Location 3460729..3461198 Replicon chromosome
Accession NZ_CP027733
Organism Pseudomonas sp. R4-39-08

Toxin (Protein)


Gene name parE_1 Uniprot ID -
Locus tag C4J88_RS15950 Protein ID WP_124404510.1
Coordinates 3460729..3461004 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag C4J88_RS15955 Protein ID WP_124407527.1
Coordinates 3461004..3461198 (-) Length 65 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4J88_RS15930 3455779..3457023 - 1245 WP_124407524.1 glutathione-dependent formaldehyde dehydrogenase -
C4J88_RS15935 3457084..3458223 - 1140 WP_124407525.1 carboxylate-amine ligase -
C4J88_RS15940 3458230..3459174 - 945 WP_124367363.1 class I SAM-dependent methyltransferase -
C4J88_RS15945 3459184..3460563 - 1380 WP_124407526.1 iron-containing redox enzyme family protein -
C4J88_RS15950 3460729..3461004 - 276 WP_124404510.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C4J88_RS15955 3461004..3461198 - 195 WP_124407527.1 stability determinant Antitoxin
C4J88_RS15960 3461574..3463315 - 1742 Protein_3099 carbohydrate ABC transporter substrate-binding protein -
C4J88_RS15965 3463476..3463748 - 273 WP_124363237.1 DUF2160 domain-containing protein -
C4J88_RS15970 3463760..3464560 - 801 WP_003232361.1 carbohydrate ABC transporter permease -
C4J88_RS15975 3464571..3465437 - 867 WP_017527241.1 sugar ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-88)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10329.00 Da        Isoelectric Point: 6.7232

>T100066 WP_124404510.1 NZ_CP027733:c3461004-3460729 [Pseudomonas sp. R4-39-08]
MLSVVWLDEAISDLIEIVTFIAAQNPGAARRLKIRLEGAPLPLTEHPYLYPNGRVPGTREVVVHPNYVLVYRVTAERIEI
VNVLHARQEYP

Download         Length: 276 bp

>T100066 NZ_CP027733:c3461004-3460729 [Pseudomonas sp. R4-39-08]
ATGTTGTCCGTTGTTTGGCTTGATGAAGCCATCAGCGACCTGATTGAAATCGTGACTTTTATCGCAGCACAAAATCCTGG
TGCTGCACGACGCCTCAAGATTCGCCTTGAAGGTGCGCCTTTACCACTGACAGAACATCCTTACTTGTATCCAAATGGTC
GTGTGCCGGGGACTCGCGAGGTCGTCGTTCACCCGAATTATGTGTTGGTGTATCGAGTGACCGCAGAGCGGATCGAGATC
GTCAACGTATTGCACGCCCGGCAGGAATACCCGTGA

Antitoxin


Download         Length: 65 a.a.        Molecular weight: 7213.13 Da        Isoelectric Point: 5.0509

>AT100066 WP_124407527.1 NZ_CP027733:c3461198-3461004 [Pseudomonas sp. R4-39-08]
MAVPLSPIVSEFETEEQASSHDLWFRKKVEKSLNNPGPGVPHDEVMARVEAIIQEAERQQRAKA

Download         Length: 195 bp

>AT100066 NZ_CP027733:c3461198-3461004 [Pseudomonas sp. R4-39-08]
ATGGCAGTTCCACTTTCCCCAATTGTTTCGGAGTTTGAAACCGAAGAGCAGGCGAGTAGCCATGATCTCTGGTTTCGTAA
AAAAGTCGAAAAAAGCCTGAACAATCCTGGCCCCGGTGTGCCCCATGATGAAGTCATGGCGAGGGTTGAAGCGATCATTC
AGGAAGCGGAGCGTCAACAGAGGGCGAAAGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References