Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 1532815..1533337 Replicon chromosome
Accession NZ_CP027733
Organism Pseudomonas sp. R4-39-08

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag C4J88_RS06880 Protein ID WP_124366221.1
Coordinates 1532815..1533108 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag C4J88_RS06885 Protein ID WP_124366222.1
Coordinates 1533098..1533337 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4J88_RS06850 1528208..1528768 - 561 WP_003189463.1 glycine cleavage system protein R -
C4J88_RS06855 1529031..1529909 + 879 WP_124406534.1 4-hydroxy-tetrahydrodipicolinate synthase -
C4J88_RS06860 1529927..1531042 + 1116 WP_124361739.1 outer membrane protein assembly factor BamC -
C4J88_RS06865 1531047..1531805 + 759 WP_124369961.1 MBL fold metallo-hydrolase -
C4J88_RS06870 1531833..1532546 + 714 WP_048726015.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
C4J88_RS06880 1532815..1533108 - 294 WP_124366221.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C4J88_RS06885 1533098..1533337 - 240 WP_124366222.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
C4J88_RS06895 1533804..1535030 - 1227 WP_124406535.1 MFS transporter -
C4J88_RS06900 1535250..1535567 - 318 WP_124406536.1 type II toxin-antitoxin system RelE/ParE family toxin -
C4J88_RS06905 1535564..1535845 - 282 WP_177412808.1 type II toxin-antitoxin system ParD family antitoxin -
C4J88_RS06910 1536178..1537080 + 903 WP_065886461.1 LysR family transcriptional regulator -
C4J88_RS06915 1537072..1537830 - 759 WP_124406537.1 substrate-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-64)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11634.49 Da        Isoelectric Point: 10.2263

>T100063 WP_124366221.1 NZ_CP027733:c1533108-1532815 [Pseudomonas sp. R4-39-08]
MIYSLDFDARALKEWQKLGDTLRQQFKKKLVKILNNPHIDANRLHGLPDCYKIKLRSSGYRLVYQVIDQEITVFVVAVDK
REHDQAYRKAFERLDRR

Download         Length: 294 bp

>T100063 NZ_CP027733:c1533108-1532815 [Pseudomonas sp. R4-39-08]
ATGATCTATAGCCTTGATTTTGATGCGCGTGCATTGAAGGAATGGCAAAAACTCGGCGACACCCTTCGTCAGCAATTCAA
GAAGAAGCTGGTCAAAATCCTGAACAACCCACACATTGACGCGAACCGCCTGCATGGCCTGCCTGACTGCTACAAGATCA
AACTGCGTAGCAGCGGGTACAGGCTGGTCTATCAAGTGATCGATCAGGAAATTACTGTGTTTGTGGTCGCCGTTGATAAA
CGTGAGCATGATCAGGCTTATCGGAAAGCGTTTGAGCGCTTGGACCGGCGCTAG

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8951.35 Da        Isoelectric Point: 4.6017

>AT100063 WP_124366222.1 NZ_CP027733:c1533337-1533098 [Pseudomonas sp. R4-39-08]
MASINIRIDDDLKARAYLELEKLGVTPSELIRQALQYVAERGQLPFKPVLMTEEDEALIATVRERLASPQRVKVSLDDL

Download         Length: 240 bp

>AT100063 NZ_CP027733:c1533337-1533098 [Pseudomonas sp. R4-39-08]
TTGGCCTCTATCAACATTCGTATCGATGACGACCTTAAGGCTCGCGCCTACCTTGAACTGGAAAAACTCGGTGTCACGCC
TTCCGAACTGATACGCCAGGCGCTGCAATATGTAGCCGAGCGCGGCCAACTGCCATTCAAGCCCGTGCTGATGACTGAAG
AAGATGAAGCCTTGATAGCGACCGTGCGTGAGCGCCTTGCGTCGCCTCAACGAGTGAAGGTTTCTTTAGATGATCTATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References