Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 709183..709776 Replicon chromosome
Accession NZ_CP027732
Organism Pseudomonas sp. R4-35-07

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag C4J89_RS03030 Protein ID WP_124415989.1
Coordinates 709474..709776 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag C4J89_RS03025 Protein ID WP_124413723.1
Coordinates 709183..709470 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4J89_RS03005 705609..707669 - 2061 WP_124413719.1 TonB-dependent copper receptor -
C4J89_RS03010 707763..708152 - 390 WP_124413720.1 DUF2946 domain-containing protein -
C4J89_RS03015 708163..708645 - 483 WP_124413721.1 copper chaperone PCu(A)C -
C4J89_RS03020 708693..709085 - 393 WP_124413722.1 DUF2946 domain-containing protein -
C4J89_RS03025 709183..709470 - 288 WP_124413723.1 putative addiction module antidote protein Antitoxin
C4J89_RS03030 709474..709776 - 303 WP_124415989.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C4J89_RS03035 710347..710595 + 249 WP_124361082.1 hypothetical protein -
C4J89_RS03040 710714..711433 - 720 WP_124413724.1 cobalt-precorrin-6A reductase -
C4J89_RS03045 711430..712635 - 1206 WP_124413725.1 precorrin-6y C5,15-methyltransferase (decarboxylating) subunit CbiE -
C4J89_RS03050 712674..714020 + 1347 WP_124413726.1 precorrin-3B synthase -
C4J89_RS03055 714013..714639 + 627 WP_124361086.1 precorrin-8X methylmutase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-96)

Antitoxin

Uncharacterized protein HI1420

(2-94)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11589.18 Da        Isoelectric Point: 10.1350

>T100056 WP_124415989.1 NZ_CP027732:c709776-709474 [Pseudomonas sp. R4-35-07]
MIRFKRSDEFQEWLDSSRGRPARGRVLVRLDNAMRGNFGDCETVGHGVSEMRIHYGPGYRVYFTRIGELVYLLLIGGDKS
TQKRDIQRAKHIADQFGKEQ

Download         Length: 303 bp

>T100056 NZ_CP027732:c709776-709474 [Pseudomonas sp. R4-35-07]
ATGATTCGATTCAAGAGATCCGACGAGTTTCAGGAGTGGCTAGATTCGTCACGCGGCAGACCCGCCCGTGGTCGTGTGCT
GGTCAGATTGGATAACGCGATGAGGGGCAATTTTGGAGACTGCGAAACCGTAGGGCATGGCGTATCGGAAATGCGCATCC
ACTATGGCCCAGGCTACCGGGTGTATTTCACGCGCATAGGTGAGCTGGTTTACCTGCTGTTGATAGGTGGCGATAAATCG
ACGCAAAAACGCGATATCCAGCGTGCAAAACACATTGCAGATCAATTTGGAAAGGAGCAGTGA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10302.76 Da        Isoelectric Point: 4.8047

>AT100056 WP_124413723.1 NZ_CP027732:c709470-709183 [Pseudomonas sp. R4-35-07]
MTQFKDFDIAEHLKTPEDMAEYLEASFEEDAGDGVLIRSALNNIARAQGMTQVARDAGLGRESLYKALSSAGNPEFATIM
KVMKALGLKLHATAI

Download         Length: 288 bp

>AT100056 NZ_CP027732:c709470-709183 [Pseudomonas sp. R4-35-07]
ATGACTCAATTTAAGGATTTTGACATAGCCGAGCATCTCAAGACCCCGGAGGACATGGCTGAATATCTTGAAGCCTCCTT
CGAAGAAGATGCCGGTGACGGTGTGCTGATTCGTTCAGCTCTTAACAACATCGCCCGCGCCCAAGGCATGACGCAGGTAG
CCCGCGATGCCGGCCTCGGACGAGAAAGTCTGTACAAAGCCCTCTCCAGCGCCGGCAATCCCGAGTTCGCGACTATCATG
AAGGTCATGAAGGCGTTGGGCCTCAAGCTTCACGCCACGGCGATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References