Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 3733624..3734839 Replicon chromosome
Accession NZ_CP027731
Organism Pseudomonas sp. R2-60-08W

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag C4J90_RS16930 Protein ID WP_124420392.1
Coordinates 3734267..3734839 (+) Length 191 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag C4J90_RS16925 Protein ID WP_124420391.1
Coordinates 3733624..3734181 (+) Length 186 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4J90_RS16895 3728940..3730016 + 1077 WP_124415093.1 aldo/keto reductase -
C4J90_RS16900 3730090..3730326 + 237 WP_124363466.1 hypothetical protein -
C4J90_RS16905 3730366..3731202 + 837 WP_124420387.1 acid phosphatase -
C4J90_RS16910 3731249..3731737 - 489 WP_124420388.1 type VI secretion system tube protein Hcp -
C4J90_RS16915 3731922..3732836 + 915 WP_124420389.1 NAD synthetase -
C4J90_RS16920 3732914..3733198 - 285 WP_124420390.1 hypothetical protein -
C4J90_RS16925 3733624..3734181 + 558 WP_124420391.1 helix-turn-helix domain-containing protein Antitoxin
C4J90_RS16930 3734267..3734839 + 573 WP_124420392.1 HD domain-containing protein Toxin
C4J90_RS16935 3734846..3735268 - 423 WP_124420393.1 RidA family protein -
C4J90_RS16940 3735446..3737029 - 1584 WP_124420394.1 FAD-dependent oxidoreductase -
C4J90_RS16945 3737041..3737964 - 924 WP_124420395.1 ABC transporter substrate-binding protein -
C4J90_RS16950 3737983..3738756 - 774 WP_124420396.1 ATP-binding cassette domain-containing protein -
C4J90_RS16955 3738749..3739720 - 972 WP_124415097.1 amino acid ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HD domain

(16-173)

Antitoxin

PAS domain

(87-182)


Sequences

Toxin        


Download         Length: 191 a.a.        Molecular weight: 21259.22 Da        Isoelectric Point: 4.7129

>T100055 WP_124420392.1 NZ_CP027731:3734267-3734839 [Pseudomonas sp. R2-60-08W]
MDMETINGRLDFLREAEKLKDVLRSAHTASGRTESTAEHSWRLCLMAMVFADQLPGLDLLKILKMCVIHDLGEAINGDIP
AVSQAAFPNKGEQERRDLLQLTQALDEPLKSQILALWDDYENALSPEAKAVKAMDKLETLLQHTQGLNPPDFDYAFNLAY
GKKHTDAAPLFEALRALIDRSTQERLDAAQ

Download         Length: 573 bp

>T100055 NZ_CP027731:3734267-3734839 [Pseudomonas sp. R2-60-08W]
ATGGACATGGAAACAATCAACGGCCGCCTCGACTTTCTGCGCGAAGCCGAGAAGCTCAAGGACGTGCTCAGAAGCGCCCA
CACCGCTTCGGGACGCACGGAAAGTACCGCTGAACACAGTTGGCGCCTGTGCCTGATGGCGATGGTGTTCGCCGATCAAC
TGCCCGGCCTGGACCTGCTTAAAATCCTCAAGATGTGCGTGATCCATGACTTGGGCGAAGCCATTAACGGTGACATTCCA
GCAGTCAGCCAGGCGGCGTTTCCCAACAAGGGCGAGCAGGAGCGGCGCGACCTGCTGCAGTTGACCCAAGCCCTGGATGA
GCCGCTGAAAAGCCAGATCCTGGCGCTGTGGGATGACTACGAGAACGCGCTGTCGCCGGAAGCCAAAGCCGTCAAGGCGA
TGGACAAGCTGGAGACCCTGCTGCAGCACACCCAGGGCCTCAACCCGCCGGATTTCGATTACGCTTTCAACCTGGCATAC
GGCAAGAAACATACGGATGCGGCGCCATTATTCGAGGCGCTGCGCGCGTTGATCGACCGTTCTACCCAGGAACGCCTCGA
CGCCGCGCAGTGA

Antitoxin


Download         Length: 186 a.a.        Molecular weight: 20558.54 Da        Isoelectric Point: 8.8045

>AT100055 WP_124420391.1 NZ_CP027731:3733624-3734181 [Pseudomonas sp. R2-60-08W]
MPHSVLKPALPGVALRRWRLLHRIKQSYAAQLFNVTQSTISRWESGVQAMDPTAHQQLEQLLAARLDAAADQALARLVSE
SSQAMHLVCDLTHRLLACSPSRARQFGSPLADLIGQSLWRFATPEIQLIEASLEHTGWRETQAPRALEFTTGSNDSNLVP
IRPSLCRWTRMTLSDGSAARLVETL

Download         Length: 558 bp

>AT100055 NZ_CP027731:3733624-3734181 [Pseudomonas sp. R2-60-08W]
ATGCCTCACTCCGTGCTCAAGCCTGCCTTGCCCGGCGTTGCGCTGCGGCGATGGCGTTTGCTGCATCGCATCAAGCAAAG
TTATGCGGCGCAATTGTTCAACGTCACGCAATCGACTATTTCGCGCTGGGAAAGTGGCGTACAAGCGATGGATCCGACTG
CGCACCAGCAGCTTGAGCAGTTGTTGGCAGCCCGGCTCGATGCAGCCGCCGATCAGGCATTGGCCCGGCTGGTCAGTGAG
AGTTCGCAAGCCATGCACCTTGTGTGCGACCTGACTCACCGCCTGCTTGCGTGCTCGCCCTCCCGCGCCCGCCAATTCGG
CAGCCCGCTCGCCGACCTTATTGGCCAGTCGCTGTGGCGCTTCGCAACGCCGGAAATCCAGTTGATCGAAGCCAGCCTGG
AGCACACCGGCTGGCGCGAAACCCAGGCACCACGGGCCCTTGAGTTCACCACGGGAAGCAACGATTCCAACCTGGTGCCC
ATACGCCCAAGCCTGTGTCGCTGGACACGTATGACCCTGAGCGATGGCAGCGCAGCACGCCTGGTCGAAACACTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References