Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 713879..714471 Replicon chromosome
Accession NZ_CP027731
Organism Pseudomonas sp. R2-60-08W

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag C4J90_RS03055 Protein ID WP_124419191.1
Coordinates 714163..714471 (-) Length 103 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag C4J90_RS03050 Protein ID WP_124361080.1
Coordinates 713879..714166 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4J90_RS03030 710305..712365 - 2061 WP_124419189.1 TonB-dependent copper receptor -
C4J90_RS03035 712459..712848 - 390 WP_124406175.1 DUF2946 domain-containing protein -
C4J90_RS03040 712859..713341 - 483 WP_124361078.1 copper chaperone PCu(A)C -
C4J90_RS03045 713389..713781 - 393 WP_124419190.1 DUF2946 domain-containing protein -
C4J90_RS03050 713879..714166 - 288 WP_124361080.1 putative addiction module antidote protein Antitoxin
C4J90_RS03055 714163..714471 - 309 WP_124419191.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C4J90_RS03060 715027..715275 + 249 WP_124361082.1 hypothetical protein -
C4J90_RS03065 715394..716113 - 720 WP_124419192.1 cobalt-precorrin-6A reductase -
C4J90_RS03070 716110..717315 - 1206 WP_124419193.1 precorrin-6y C5,15-methyltransferase (decarboxylating) subunit CbiE -
C4J90_RS03075 717354..718700 + 1347 WP_124419194.1 precorrin-3B synthase -
C4J90_RS03080 718693..719319 + 627 WP_124361086.1 precorrin-8X methylmutase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(4-93)

Antitoxin

Uncharacterized protein HI1420

(4-94)


Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 11787.47 Da        Isoelectric Point: 10.4237

>T100050 WP_124419191.1 NZ_CP027731:c714471-714163 [Pseudomonas sp. R2-60-08W]
MIRFKRSVEFQEWLDSSRGRPARGRVLVRLDNAMRGNFGDCETVGHGVSEMRIHYGPGYRVYFTRIGELVYLLLIGGDKS
TQKRDIQRAKHMQINLERSGDS

Download         Length: 309 bp

>T100050 NZ_CP027731:c714471-714163 [Pseudomonas sp. R2-60-08W]
ATGATTCGATTCAAGAGATCCGTCGAGTTTCAGGAGTGGCTAGATTCGTCACGCGGCAGACCCGCCCGTGGTCGTGTGCT
GGTCAGATTGGATAACGCGATGAGGGGCAATTTTGGAGACTGCGAAACCGTAGGGCATGGCGTATCGGAAATGCGCATCC
ACTATGGCCCAGGCTACCGGGTGTATTTCACGCGCATAGGTGAGCTGGTTTACCTGCTGTTGATAGGTGGCGATAAATCG
ACGCAAAAACGCGATATCCAGCGTGCAAAACACATGCAGATCAATTTGGAAAGGAGCGGTGACTCATGA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10314.81 Da        Isoelectric Point: 4.8047

>AT100050 WP_124361080.1 NZ_CP027731:c714166-713879 [Pseudomonas sp. R2-60-08W]
MIQFKDFDIAEHLKTPEDMAEYLEASFEEDAGDGVLIRSALNNIARAQGMTQVARDAGLGRESLYKALSSAGNPEFATIM
KVMKALGLKLHATAI

Download         Length: 288 bp

>AT100050 NZ_CP027731:c714166-713879 [Pseudomonas sp. R2-60-08W]
ATGATTCAATTTAAGGATTTTGACATAGCCGAGCATCTCAAGACCCCGGAGGACATGGCTGAATATCTTGAAGCCTCCTT
CGAAGAAGATGCCGGTGACGGCGTGCTGATTCGTTCAGCTCTTAACAACATAGCCCGCGCCCAAGGCATGACGCAGGTAG
CCCGCGATGCCGGCCTCGGACGAGAAAGTCTGTACAAAGCCCTCTCCAGCGCCGGCAATCCCGAGTTCGCGACTATCATG
AAGGTCATGAAGGCGTTGGGCCTCAAGCTTCACGCCACGGCGATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References