Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 3814583..3815799 Replicon chromosome
Accession NZ_CP027730
Organism Pseudomonas sp. R3-52-08

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag C4J91_RS17375 Protein ID WP_124363469.1
Coordinates 3815227..3815799 (+) Length 191 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag C4J91_RS17370 Protein ID WP_124363468.1
Coordinates 3814583..3815140 (+) Length 186 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4J91_RS17345 3809956..3811080 - 1125 WP_124363463.1 ThiF family adenylyltransferase -
C4J91_RS17350 3811157..3811261 - 105 WP_124363464.1 pantocin A family RiPP -
C4J91_RS17355 3811782..3812858 + 1077 WP_124363465.1 aldo/keto reductase -
C4J91_RS17360 3812932..3813168 + 237 WP_124363466.1 hypothetical protein -
C4J91_RS17365 3813208..3814038 + 831 WP_124363467.1 acid phosphatase -
C4J91_RS17370 3814583..3815140 + 558 WP_124363468.1 helix-turn-helix domain-containing protein Antitoxin
C4J91_RS17375 3815227..3815799 + 573 WP_124363469.1 HD domain-containing protein Toxin
C4J91_RS17380 3815806..3816228 - 423 WP_124363470.1 RidA family protein -
C4J91_RS17385 3816406..3817989 - 1584 WP_124363471.1 FAD-dependent oxidoreductase -
C4J91_RS17390 3818001..3818924 - 924 WP_124363472.1 ABC transporter substrate-binding protein -
C4J91_RS17395 3818943..3819716 - 774 WP_124363473.1 amino acid ABC transporter ATP-binding protein -
C4J91_RS17400 3819709..3820680 - 972 WP_124363474.1 amino acid ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

5'-deoxynucleotidase YfbR/HDDC2

(9-187)

Antitoxin

Cro/C1-type helix-turn-helix domain

(12-62)


Sequences

Toxin        


Download         Length: 191 a.a.        Molecular weight: 21316.35 Da        Isoelectric Point: 4.9538

>T100049 WP_124363469.1 NZ_CP027730:3815227-3815799 [Pseudomonas sp. R3-52-08]
MDFEKIKGRLDFLREAEKLKDVLRSAHTASGRTESTAEHSWRLCLMAMVFADQLPGLDLLKILKMCVIHDLGEAINGDIP
AVSQAAFPNKGEQERRDLLQLTQALDEPLKSQILALWDDYENALSPEAKAVKAMDKLETLLQHTQGLNPPDFDYAFNLAY
GKKHTDAAPLFEALRALIDRSTQERLDAAQ

Download         Length: 573 bp

>T100049 NZ_CP027730:3815227-3815799 [Pseudomonas sp. R3-52-08]
ATGGACTTCGAGAAAATCAAAGGCCGCCTCGACTTTCTGCGCGAAGCCGAGAAGCTCAAGGACGTGCTCAGAAGCGCCCA
CACCGCTTCGGGACGCACGGAAAGTACCGCTGAACACAGTTGGCGCCTGTGCCTGATGGCGATGGTGTTCGCCGATCAAC
TGCCCGGCCTGGACCTGCTTAAAATCCTCAAGATGTGCGTGATCCATGACTTGGGCGAAGCCATTAACGGTGACATTCCA
GCAGTCAGCCAGGCGGCGTTTCCCAACAAGGGCGAGCAGGAGCGGCGCGACCTGCTGCAGTTGACCCAAGCCCTGGATGA
GCCGCTGAAAAGCCAGATCCTGGCGCTGTGGGATGACTACGAGAACGCGCTGTCGCCGGAAGCCAAAGCCGTCAAGGCGA
TGGACAAGCTGGAGACCCTGCTGCAGCACACCCAGGGCCTCAACCCGCCGGATTTCGATTACGCCTTCAACCTGGCATAC
GGCAAGAAACATACGGATGCGGCGCCATTATTCGAGGCGCTGCGCGCGTTGATCGACCGTTCTACCCAGGAACGCCTCGA
CGCCGCGCAGTGA

Antitoxin


Download         Length: 186 a.a.        Molecular weight: 20567.62 Da        Isoelectric Point: 9.5869

>AT100049 WP_124363468.1 NZ_CP027730:3814583-3815140 [Pseudomonas sp. R3-52-08]
MPALLLQPAIPGIALRRWRLLHRVKQTHAAQMFNVNQSTLSRWENGLQAMDAAAHQQLERLLSARLDTAADQALAGLVRD
SSRAVHLVCDLTHRFLACSPSRAAQFSRPLVDLMGQSLWRYATAEIRQVEAALDHTGWRENQAPPALQFCTGSNDSSLVP
IRPSLCRWTRLILSDGSAARLVETL

Download         Length: 558 bp

>AT100049 NZ_CP027730:3814583-3815140 [Pseudomonas sp. R3-52-08]
ATGCCCGCCCTGCTGCTCCAGCCCGCCATTCCGGGCATTGCGCTGCGCCGATGGCGCCTGTTACACCGCGTCAAGCAAAC
CCATGCCGCACAGATGTTCAACGTAAACCAATCGACGTTGTCCCGCTGGGAGAATGGCCTGCAAGCCATGGACGCTGCCG
CGCACCAACAGCTGGAACGGTTGCTGTCCGCTCGGCTTGACACCGCAGCTGATCAGGCCCTGGCTGGGCTGGTCAGAGAC
AGCTCGCGCGCCGTACACCTGGTGTGCGACCTGACGCACCGCTTCCTGGCCTGTTCGCCCTCCCGCGCCGCACAGTTCAG
CCGCCCGTTGGTCGACTTGATGGGCCAATCGCTGTGGCGTTATGCGACAGCGGAAATCCGCCAGGTGGAAGCTGCGCTGG
ATCACACCGGCTGGCGCGAGAACCAGGCGCCGCCAGCGCTTCAATTCTGCACCGGCAGCAACGACTCCAGCCTCGTGCCG
ATCCGCCCAAGCCTGTGTCGCTGGACACGCCTGATCCTCAGCGATGGCAGCGCCGCGCGTCTGGTCGAGACGCTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References