Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 691179..691772 Replicon chromosome
Accession NZ_CP027730
Organism Pseudomonas sp. R3-52-08

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag C4J91_RS02960 Protein ID WP_124361081.1
Coordinates 691470..691772 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag C4J91_RS02955 Protein ID WP_124361080.1
Coordinates 691179..691466 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4J91_RS02935 687605..689665 - 2061 WP_124361076.1 TonB-dependent copper receptor -
C4J91_RS02940 689759..690106 - 348 WP_177412842.1 DUF2946 domain-containing protein -
C4J91_RS02945 690159..690641 - 483 WP_124361078.1 copper chaperone PCu(A)C -
C4J91_RS02950 690689..691081 - 393 WP_124361079.1 DUF2946 domain-containing protein -
C4J91_RS02955 691179..691466 - 288 WP_124361080.1 putative addiction module antidote protein Antitoxin
C4J91_RS02960 691470..691772 - 303 WP_124361081.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C4J91_RS02965 692393..692641 + 249 WP_124361082.1 hypothetical protein -
C4J91_RS02970 692760..693479 - 720 WP_124361083.1 cobalt-precorrin-6A reductase -
C4J91_RS02975 693476..694681 - 1206 WP_124361084.1 precorrin-6y C5,15-methyltransferase (decarboxylating) subunit CbiE -
C4J91_RS02980 694720..696066 + 1347 WP_124361085.1 precorrin-3B synthase -
C4J91_RS02985 696059..696685 + 627 WP_124361086.1 precorrin-8X methylmutase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-96)

Antitoxin

Uncharacterized protein HI1420

(4-94)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11563.15 Da        Isoelectric Point: 10.2734

>T100044 WP_124361081.1 NZ_CP027730:c691772-691470 [Pseudomonas sp. R3-52-08]
MIRFKRSDEFQEWLDSSRGRPARGRVLVRLDNAMRGNFGDCETVGHGVSEMRIHHGPGYRVYFTRIGELVYLLLIGGDKS
TQKRDIQRAKHIADQFGKEQ

Download         Length: 303 bp

>T100044 NZ_CP027730:c691772-691470 [Pseudomonas sp. R3-52-08]
ATGATTCGATTCAAGAGATCCGACGAGTTTCAGGAGTGGCTAGATTCGTCACGCGGCAGACCCGCCCGTGGTCGTGTGCT
GGTCAGATTGGATAACGCGATGAGGGGCAATTTTGGAGACTGCGAAACCGTAGGGCATGGCGTATCGGAAATGCGCATCC
ACCATGGCCCAGGCTACCGGGTGTATTTCACGCGCATAGGTGAGCTGGTTTACCTGCTGTTGATAGGTGGCGATAAATCG
ACGCAAAAACGCGATATCCAGCGTGCAAAACACATCGCAGATCAATTTGGAAAGGAGCAGTGA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10314.81 Da        Isoelectric Point: 4.8047

>AT100044 WP_124361080.1 NZ_CP027730:c691466-691179 [Pseudomonas sp. R3-52-08]
MIQFKDFDIAEHLKTPEDMAEYLEASFEEDAGDGVLIRSALNNIARAQGMTQVARDAGLGRESLYKALSSAGNPEFATIM
KVMKALGLKLHATAI

Download         Length: 288 bp

>AT100044 NZ_CP027730:c691466-691179 [Pseudomonas sp. R3-52-08]
ATGATTCAATTTAAGGATTTTGACATAGCCGAGCATCTCAAGACCCCGGAGGACATGGCTGAATATCTTGAAGCCTCCTT
CGAAGAAGATGCCGGTGACGGCGTGCTGATTCGTTCAGCTCTTAACAACATAGCCCGCGCCCAAGGCATGACGCAGGTAG
CCCGCGATGCCGGCCTCGGACGAGAAAGTCTGTACAAAGCCCTCTCCAGCGCTGGCAATCCCGAGTTCGCGACTATCATG
AAGGTCATGAAGGCGTTGGGCCTCAAGCTTCACGCCACGGCGATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References