100043

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 5090721..5092456 Replicon chromosome
Accession NZ_CP027729
Organism Pseudomonas sp. R3-18-08

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag C4J92_RS23390 Protein ID WP_124405398.1
Coordinates 5090721..5091365 (+) Length 215 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag C4J92_RS23395 Protein ID WP_124371997.1
Coordinates 5091362..5092456 (+) Length 365 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4J92_RS23360 5086354..5086881 + 528 WP_003176323.1 inorganic diphosphatase -
C4J92_RS23365 5087091..5087855 + 765 WP_124405396.1 helix-turn-helix transcriptional regulator -
C4J92_RS23375 5088098..5089201 - 1104 WP_124371994.1 DUF91 domain-containing protein -
C4J92_RS23380 5089417..5089653 - 237 WP_124405397.1 hypothetical protein -
C4J92_RS23385 5090152..5090724 + 573 WP_124371995.1 DUF4433 domain-containing protein -
C4J92_RS23390 5090721..5091365 + 645 WP_124405398.1 DUF4433 domain-containing protein Toxin
C4J92_RS23395 5091362..5092456 + 1095 WP_124371997.1 macro domain-containing protein Antitoxin
C4J92_RS23400 5092524..5092667 + 144 Protein_4528 hydrolase -
C4J92_RS23405 5092754..5093467 - 714 Protein_4529 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
C4J92_RS23410 5093457..5094221 - 765 WP_124405399.1 type IV toxin-antitoxin system AbiEi family antitoxin -
C4J92_RS23415 5094430..5095062 + 633 WP_003239464.1 hydrolase -
C4J92_RS23420 5095124..5096155 - 1032 WP_124405400.1 DUF1016 family protein -
C4J92_RS23430 5096349..5096525 + 177 WP_124372000.1 MerR family DNA-binding transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 5089417..5102766 13349


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(14-213)

Antitoxin

Macro domain

(18-130)


Sequences

Toxin        


Download         Length: 215 a.a.        Molecular weight: 24812.36 Da        Isoelectric Point: 6.7178

>T100043 WP_124405398.1 NZ_CP027729:5090721-5091365 [Pseudomonas sp. R3-18-08]
MIYNNLNPEKALIWRIVHRDNLPWILDNGLHCASSEVHAAQYVNIGNVDLIDKRRTRCVPIAPSGFLSDYVPFYFTPFSV
MMKNIHSGWSVQQRSNDEIVILVSSLHRVAELGLPFVFTNAHAYPDWTDYYSDLANLHEIDWSILQRRDFKRDPDDPRKM
ERYQAEALIHHHLPITGLLGIMCYADAMKERIEQDVAARGLTLPVHARPGWYFP

Download         Length: 645 bp

>T100043 NZ_CP027729:5090721-5091365 [Pseudomonas sp. R3-18-08]
ATGATTTATAACAACCTGAATCCTGAAAAAGCTCTGATCTGGCGAATCGTTCATCGCGACAATTTGCCCTGGATTCTGGA
CAACGGCCTGCACTGCGCCAGCTCAGAGGTGCATGCTGCGCAATATGTGAACATAGGCAATGTTGATTTAATCGACAAAC
GCCGCACGCGCTGTGTCCCCATTGCTCCTTCAGGCTTTTTGTCAGACTACGTTCCCTTCTATTTCACACCCTTCTCTGTG
ATGATGAAAAATATTCATTCCGGCTGGAGCGTTCAGCAACGCAGCAATGACGAGATCGTGATTCTGGTCTCCAGCCTCCA
CCGCGTCGCCGAGCTTGGCCTACCGTTCGTCTTCACAAATGCACATGCGTACCCGGATTGGACAGACTATTACAGCGACC
TGGCGAATCTCCACGAGATCGATTGGTCTATCCTTCAACGGCGTGACTTCAAACGTGACCCCGATGACCCTCGCAAAATG
GAGCGTTATCAGGCTGAAGCGCTGATTCACCACCACTTACCGATTACAGGACTCCTTGGCATCATGTGTTACGCCGATGC
GATGAAAGAACGCATAGAGCAGGACGTCGCCGCAAGAGGCCTGACGTTGCCTGTACATGCTCGTCCGGGATGGTATTTCC
CATGA

Antitoxin


Download         Length: 365 a.a.        Molecular weight: 41201.24 Da        Isoelectric Point: 6.2456

>AT100043 WP_124371997.1 NZ_CP027729:5091362-5092456 [Pseudomonas sp. R3-18-08]
MIRFTQGNLLEANTEVLVNTVNTVGVMGKGIALMFKERFAENYRLYAAACKAGEVKTGEVHVTAVNELDGPRWIVNFPTK
RHWRSPSQMAWIIEGLHDLRRFLIENHVKSVAVPPLGAGNGGLKWPDVREQIEDVLSDLDVDVLVFEPSNQYLNVAKRNG
VEKLTPARALIAELVRRYWVLGMECSLLEIQKLAWFLERAIEKRPGLKNPLDLKFVAHKYGPYANRLEHLLNNLDGSYLH
CDKRISDAENSDVIWFDQDRRAFLQTYLRTEAKEYSQALELTAELIDGFESPFGMELLATVDWLLTQEDVAPTVPALREA
LKQWDGGVAAAARKNKLFDDQALDIALKRLTSSSFSHQMASCHI

Download         Length: 1095 bp

>AT100043 NZ_CP027729:5091362-5092456 [Pseudomonas sp. R3-18-08]
ATGATCAGATTCACCCAGGGTAACCTTCTGGAAGCCAACACCGAAGTCCTCGTCAACACGGTGAATACCGTGGGCGTGAT
GGGCAAGGGCATCGCGCTGATGTTCAAGGAGCGTTTTGCAGAAAACTATCGCTTGTACGCTGCTGCCTGTAAAGCTGGCG
AAGTAAAGACCGGAGAAGTGCACGTAACTGCGGTCAACGAACTGGACGGTCCTCGCTGGATCGTTAACTTCCCGACCAAA
CGTCACTGGCGATCACCATCGCAGATGGCATGGATAATCGAAGGCCTGCACGACCTCCGTCGTTTTCTGATTGAAAACCA
TGTGAAGTCGGTTGCGGTTCCTCCGTTAGGGGCCGGTAACGGTGGTCTGAAATGGCCGGACGTTCGCGAACAGATTGAGG
ATGTCTTGAGCGATCTGGATGTCGATGTGTTGGTTTTTGAGCCATCCAATCAGTATCTGAATGTCGCCAAACGCAACGGT
GTAGAAAAGCTTACGCCTGCGCGAGCGCTCATTGCGGAACTGGTTCGACGCTACTGGGTGTTAGGCATGGAATGCAGCCT
GCTTGAGATTCAGAAACTGGCTTGGTTCCTGGAACGCGCAATTGAGAAGCGGCCAGGCCTCAAAAACCCACTGGATCTTA
AATTTGTTGCTCATAAGTACGGGCCGTATGCCAATCGGCTGGAACACCTGCTTAACAATCTGGACGGTAGTTATCTGCAT
TGCGATAAGCGAATCAGCGATGCGGAAAACAGTGATGTGATCTGGTTTGACCAAGACCGCAGAGCCTTTCTACAAACCTA
TCTCAGAACAGAAGCCAAGGAATATTCCCAGGCCTTGGAGCTTACCGCGGAGTTGATTGATGGCTTTGAGTCACCCTTCG
GCATGGAGCTATTGGCAACAGTCGACTGGCTGCTGACCCAGGAAGATGTAGCCCCGACGGTTCCGGCTTTACGTGAGGCA
CTGAAACAATGGGATGGCGGTGTCGCTGCAGCCGCTCGCAAAAACAAGCTGTTTGACGATCAAGCACTTGATATTGCGCT
TAAACGGCTCACTTCCAGCAGCTTCAGCCATCAAATGGCTTCCTGTCATATATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References