100042

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 4742624..4743666 Replicon chromosome
Accession NZ_CP027729
Organism Pseudomonas sp. R3-18-08

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag C4J92_RS21755 Protein ID WP_124371779.1
Coordinates 4742624..4743199 (-) Length 192 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID -
Locus tag C4J92_RS21760 Protein ID WP_124405219.1
Coordinates 4743196..4743666 (-) Length 157 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4J92_RS21720 4738496..4738831 + 336 WP_124405214.1 hypothetical protein -
C4J92_RS21725 4738902..4739252 - 351 WP_124405846.1 hypothetical protein -
C4J92_RS21730 4739464..4739793 + 330 WP_124405215.1 hypothetical protein -
C4J92_RS21735 4739755..4740402 - 648 WP_124405216.1 LysE family transporter -
C4J92_RS21740 4740668..4741360 + 693 WP_124405847.1 helix-turn-helix domain-containing protein -
C4J92_RS21745 4741362..4741997 - 636 WP_124405217.1 LysE family translocator -
C4J92_RS21750 4742134..4742505 + 372 WP_124405218.1 PH domain-containing protein -
C4J92_RS21755 4742624..4743199 - 576 WP_124371779.1 PIN domain-containing protein Toxin
C4J92_RS21760 4743196..4743666 - 471 WP_124405219.1 helix-turn-helix domain-containing protein Antitoxin
C4J92_RS21765 4743851..4744120 + 270 Protein_4215 detoxification -
C4J92_RS21770 4744173..4744460 + 288 WP_124405220.1 cloacin -
C4J92_RS21775 4744477..4744947 + 471 WP_124405848.1 hypothetical protein -
C4J92_RS21780 4744996..4745370 - 375 WP_124364321.1 cytochrome c family protein -
C4J92_RS21785 4745595..4745975 + 381 WP_124364322.1 response regulator -
C4J92_RS21790 4746169..4746783 + 615 WP_124405221.1 biliverdin-producing heme oxygenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 4733535..4745975 12440


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(9-115)

Antitoxin

Helix-turn-helix domain, group 17

(84-132)


Sequences

Toxin        


Download         Length: 192 a.a.        Molecular weight: 21699.18 Da        Isoelectric Point: 5.0478

>T100042 WP_124371779.1 NZ_CP027729:c4743199-4742624 [Pseudomonas sp. R3-18-08]
MRCSPFTAVYDACVLYPAALRDLLMWLGLSGLYRARWTRQIHEEWKRNVLKNRPDLTPDQVDKISALMDKAIPDALVTGY
EDLCSSLDLPDPDDRHVLAAAIRSKAEVIVTFNLKDFPVRVLAAYDIEPMHPDDFISDLWDLDQAAVLAAVQKQRRALVR
PPMNGEGYLEMLMRQGLVQTSKLLGPYEVML

Download         Length: 576 bp

>T100042 NZ_CP027729:c4743199-4742624 [Pseudomonas sp. R3-18-08]
ATGAGGTGTTCGCCTTTCACTGCGGTTTACGACGCCTGTGTTCTGTACCCGGCGGCTCTCAGGGATTTGTTGATGTGGCT
TGGTTTATCCGGGTTGTACCGGGCGCGATGGACCCGACAGATTCATGAAGAGTGGAAGCGTAACGTTCTCAAGAACCGAC
CTGATCTCACTCCCGACCAGGTAGATAAAATTTCGGCATTGATGGACAAGGCCATACCGGACGCGTTGGTAACAGGGTAC
GAAGACTTGTGTTCAAGTTTGGATTTGCCTGATCCAGATGATCGTCACGTACTGGCCGCGGCGATTCGGAGTAAGGCGGA
AGTTATCGTGACCTTTAACTTGAAAGACTTTCCAGTGCGGGTACTCGCGGCTTATGACATAGAACCGATGCATCCCGACG
ACTTTATCTCGGACCTTTGGGACTTGGATCAAGCAGCCGTGTTGGCGGCAGTGCAGAAGCAGAGGCGTGCACTAGTTAGG
CCGCCGATGAATGGGGAAGGGTATCTCGAGATGTTGATGCGGCAGGGGCTAGTGCAGACCAGTAAGCTGCTTGGGCCTTA
TGAGGTAATGTTGTAG

Antitoxin


Download         Length: 157 a.a.        Molecular weight: 17661.30 Da        Isoelectric Point: 5.6533

>AT100042 WP_124405219.1 NZ_CP027729:c4743666-4743196 [Pseudomonas sp. R3-18-08]
MITNHLPKTIPPLEKEVEAAVQGQRELASLLSTKFETQRIDIFDKEDKPHTLVLPTSALRLLVDILGELALGNAVKVVPV
HAELTSQEAADLLNVSRPHLVKMLEEGAIPFTKTGRHRRIRFSDLMAFKQRRDEESQEAMEELVRQTRELGLGYDE

Download         Length: 471 bp

>AT100042 NZ_CP027729:c4743666-4743196 [Pseudomonas sp. R3-18-08]
ATGATCACCAATCACCTTCCCAAAACAATTCCTCCGCTGGAAAAGGAAGTCGAAGCCGCTGTGCAAGGCCAACGCGAGCT
GGCTTCGTTGCTATCGACTAAATTCGAAACCCAGCGCATCGACATCTTCGACAAAGAAGACAAGCCCCACACCCTTGTAC
TCCCCACATCCGCGCTGCGCCTGCTGGTTGATATTTTGGGTGAGCTGGCGCTGGGTAATGCCGTCAAAGTTGTACCAGTC
CATGCTGAGTTGACCTCCCAGGAAGCTGCCGACCTGCTTAACGTTTCACGCCCGCATCTGGTCAAGATGCTGGAAGAAGG
CGCCATTCCCTTTACGAAGACCGGTCGTCATCGGCGTATTCGATTTTCCGATTTGATGGCGTTCAAACAGCGCCGCGATG
AAGAAAGTCAAGAGGCGATGGAGGAACTGGTACGGCAGACCCGGGAGTTGGGATTGGGGTATGACGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References