100040

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 3705557..3706772 Replicon chromosome
Accession NZ_CP027729
Organism Pseudomonas sp. R3-18-08

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag C4J92_RS16920 Protein ID WP_124404670.1
Coordinates 3706200..3706772 (+) Length 191 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag C4J92_RS16915 Protein ID WP_124404669.1
Coordinates 3705557..3706114 (+) Length 186 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4J92_RS16885 3700763..3701734 - 972 WP_124404666.1 cysteine synthase family protein -
C4J92_RS16890 3702224..3703300 + 1077 WP_124371208.1 aldo/keto reductase -
C4J92_RS16895 3703371..3703607 + 237 WP_124363466.1 hypothetical protein -
C4J92_RS16900 3703647..3704477 + 831 WP_124404667.1 acid phosphatase -
C4J92_RS16910 3704951..3705241 - 291 WP_124404668.1 hypothetical protein -
C4J92_RS16915 3705557..3706114 + 558 WP_124404669.1 helix-turn-helix domain-containing protein Antitoxin
C4J92_RS16920 3706200..3706772 + 573 WP_124404670.1 HD domain-containing protein Toxin
C4J92_RS16925 3706779..3707201 - 423 WP_124404671.1 RidA family protein -
C4J92_RS16930 3707213..3708796 - 1584 WP_124404672.1 FAD-dependent oxidoreductase -
C4J92_RS16935 3708808..3709731 - 924 WP_124404673.1 ABC transporter substrate-binding protein -
C4J92_RS16940 3709750..3710523 - 774 WP_124404674.1 amino acid ABC transporter ATP-binding protein -
C4J92_RS16945 3710516..3711487 - 972 WP_124404675.1 amino acid ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

5'-deoxynucleotidase YfbR/HDDC2

(9-185)

Antitoxin

Cro/C1-type helix-turn-helix domain

(12-46)


Sequences

Toxin        


Download         Length: 191 a.a.        Molecular weight: 21286.34 Da        Isoelectric Point: 4.9417

>T100040 WP_124404670.1 NZ_CP027729:3706200-3706772 [Pseudomonas sp. R3-18-08]
MDMETIKGRLDFLREAEKLKDVLRSAHTASGRTESTAEHTWRLCLMAMVFADQLPGLDLLKILKMCVIHDLGEAINGDIP
AVSQAAFPNKGEQERRDLLQLTQALDGPLKSQILTLWDDYENALSPEAKAVKAMDKLETLLQHTQGLNPPDFNYAFNLAY
GKKHTDAEPLFEALRALIDRATQERLDAAQ

Download         Length: 573 bp

>T100040 NZ_CP027729:3706200-3706772 [Pseudomonas sp. R3-18-08]
ATGGACATGGAAACAATCAAAGGCCGCCTCGACTTTCTGCGCGAAGCCGAGAAACTCAAGGACGTGCTCAGAAGCGCCCA
CACCGCTTCGGGACGCACGGAAAGTACCGCCGAACACACTTGGCGCCTGTGCCTGATGGCAATGGTGTTCGCCGATCAAT
TGCCCGGCCTGGACCTGCTTAAAATCCTCAAGATGTGCGTGATCCATGACTTGGGCGAAGCCATTAACGGCGACATTCCA
GCAGTCAGCCAGGCGGCGTTTCCCAACAAGGGCGAGCAGGAGCGGCGCGACCTGCTGCAGTTGACCCAAGCCCTGGATGG
GCCCCTGAAAAGCCAGATCCTGACGTTGTGGGATGACTACGAGAACGCACTGTCGCCGGAAGCCAAAGCCGTCAAGGCGA
TGGACAAGCTGGAGACCCTGCTGCAGCACACCCAGGGCCTCAACCCGCCGGATTTCAATTACGCTTTCAACCTGGCATAC
GGCAAGAAACATACGGATGCCGAGCCCTTATTCGAGGCGCTGCGTGCGCTGATCGACCGCGCTACCCAGGAACGCCTCGA
CGCCGCGCAGTGA

Antitoxin


Download         Length: 186 a.a.        Molecular weight: 20451.43 Da        Isoelectric Point: 8.8378

>AT100040 WP_124404669.1 NZ_CP027729:3705557-3706114 [Pseudomonas sp. R3-18-08]
MPHSLLKPALPGVALRRWRLLHRIKQSHAAQLFNVTQSTISRWESGVQAMDPAGHQQLEQLLAARLDAAADQALARLVSE
SSQAMHLVCDLTHRLLACSPSRARQFGSPLADLIGQSLWRFATPQIQLIEASLEHTGWRESQAPPALEFTTGSNDSHLVP
IRPSLCRWTRMTLSDGSAARLVETL

Download         Length: 558 bp

>AT100040 NZ_CP027729:3705557-3706114 [Pseudomonas sp. R3-18-08]
ATGCCTCATTCCTTGCTCAAGCCTGCCTTGCCCGGCGTTGCGCTGCGGCGATGGCGTTTGCTGCATCGCATCAAGCAAAG
CCATGCGGCACAGTTGTTCAACGTCACGCAATCGACTATTTCGCGCTGGGAAAGTGGCGTGCAAGCGATGGATCCGGCTG
GGCACCAGCAGCTTGAGCAGTTGTTGGCAGCCCGGCTTGATGCAGCCGCCGATCAGGCATTGGCCCGGCTGGTCAGTGAG
AGCTCGCAAGCCATGCACCTGGTGTGCGACCTGACTCACCGCTTGCTCGCGTGCTCGCCCTCCCGCGCACGCCAATTCGG
CAGCCCGCTTGCCGACCTTATTGGCCAGTCGCTGTGGCGCTTCGCAACGCCGCAAATCCAGCTGATCGAAGCCAGCCTGG
AGCACACCGGCTGGCGCGAAAGCCAGGCACCACCGGCCCTTGAGTTCACCACGGGAAGCAATGATTCCCACCTCGTGCCC
ATACGCCCTAGCCTGTGTCGCTGGACACGTATGACCCTGAGCGATGGCAGCGCAGCACGTCTGGTCGAAACACTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References