Detailed information of TA system TA100039

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): parE_1-relB/RelE(toxin)
• Location: 3419406..3419875
• Replicon: chromosome
• Accession: NZ_CP027729
• Organism: Pseudomonas sp. R3-18-08

Toxin (Protein)

• Gene name: parE_1
• Uniprot ID: -
• Locus tag: C4J92_RS15585
• Protein ID: WP_124404510.1
• Coordinates: 3419406..3419681 (-)
• Length: 92 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: C4J92_RS15590
• Protein ID: WP_124404511.1
• Coordinates: 3419681..3419875 (-)
• Length: 65 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C4J92_RS15565	3414418..3415662	-	1245	WP_124404506.1	glutathione-dependent formaldehyde dehydrogenase	-
C4J92_RS15570	3415723..3416862	-	1140	WP_124404507.1	carboxylate-amine ligase	-
C4J92_RS15575	3416869..3417813	-	945	WP_124404508.1	class I SAM-dependent methyltransferase	-
C4J92_RS15580	3417824..3419203	-	1380	WP_124404509.1	iron-containing redox enzyme family protein	-
C4J92_RS15585	3419406..3419681	-	276	WP_124404510.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
C4J92_RS15590	3419681..3419875	-	195	WP_124404511.1	stability determinant	Antitoxin
C4J92_RS15595	3420135..3421877	-	1743	WP_124363236.1	ABC transporter substrate-binding protein	-
C4J92_RS15600	3422038..3422310	-	273	WP_124363237.1	DUF2160 domain-containing protein	-
C4J92_RS15605	3422322..3423122	-	801	WP_003232361.1	carbohydrate ABC transporter permease	-
C4J92_RS15610	3423133..3423999	-	867	WP_124363238.1	sugar ABC transporter permease	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-88)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 92 a.a.
• Molecular weight: 10329.00 Da
• Isoelectric Point: 6.7232

>T100039 WP_124404510.1 NZ_CP027729:c3419681-3419406 [Pseudomonas sp. R3-18-08]
MLSVVWLDEAISDLIEIVTFIAAQNPGAARRLKIRLEGAPLPLTEHPYLYPNGRVPGTREVVVHPNYVLVYRVTAERIEI
VNVLHARQEYP

Nucleotide

• Length: 276 bp

>T100039 NZ_CP027729:c3419681-3419406 [Pseudomonas sp. R3-18-08]
ATGCTGTCCGTTGTTTGGCTTGATGAAGCCATCAGCGACCTGATTGAAATCGTGACTTTTATCGCAGCACAAAATCCTGG
TGCTGCACGACGCCTCAAGATTCGGCTTGAAGGTGCGCCTTTACCACTGACAGAACATCCTTACTTGTATCCAAACGGTC
GTGTGCCGGGGACTCGCGAGGTCGTCGTTCACCCGAATTATGTGTTGGTGTATCGAGTGACCGCAGAGCGGATCGAGATC
GTCAACGTTTTGCACGCCCGGCAGGAATACCCCTGA

Antitoxin

Protein

• Length: 65 a.a.
• Molecular weight: 7200.13 Da
• Isoelectric Point: 5.0509

>AT100039 WP_124404511.1 NZ_CP027729:c3419875-3419681 [Pseudomonas sp. R3-18-08]
MAVPLSPIVSEFETEEQASSHDLWFRKKVEKSLTNPGPGVPHDEVMARVEAIIQEAERQQRAKA

Nucleotide

• Length: 195 bp

>AT100039 NZ_CP027729:c3419875-3419681 [Pseudomonas sp. R3-18-08]
ATGGCAGTTCCACTTTCCCCAATTGTTTCGGAGTTTGAAACTGAAGAGCAGGCGAGTAGCCATGATCTCTGGTTTCGTAA
AAAAGTCGAAAAAAGCCTGACCAATCCTGGCCCCGGTGTGCCCCATGATGAAGTCATGGCGAGGGTTGAAGCGATCATTC
AGGAAGCGGAGCGTCAACAGAGGGCTAAAGCCTGA