Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-YefM
Location 4768390..4768895 Replicon chromosome
Accession NZ_CP027728
Organism Pseudomonas sp. R2-37-08W

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag C4J93_RS22005 Protein ID WP_124408130.1
Coordinates 4768641..4768895 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag C4J93_RS22000 Protein ID WP_124368289.1
Coordinates 4768390..4768644 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4J93_RS21980 4763598..4763804 + 207 WP_124368285.1 hypothetical protein -
C4J93_RS21985 4763918..4765810 + 1893 WP_124430453.1 alkaline phosphatase family protein -
C4J93_RS21990 4765928..4766941 + 1014 WP_124430454.1 diguanylate cyclase -
C4J93_RS21995 4767047..4768296 + 1250 Protein_4256 aspartate aminotransferase family protein -
C4J93_RS22000 4768390..4768644 + 255 WP_124368289.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
C4J93_RS22005 4768641..4768895 + 255 WP_124408130.1 Txe/YoeB family addiction module toxin Toxin
C4J93_RS22010 4768998..4769714 + 717 WP_124430455.1 hypothetical protein -
C4J93_RS22015 4769724..4770845 - 1122 WP_124430456.1 aminotransferase class V-fold PLP-dependent enzyme -
C4J93_RS22020 4770847..4772049 - 1203 WP_124430457.1 MFS transporter -
C4J93_RS22025 4772049..4773299 - 1251 WP_124364335.1 ATP-grasp domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10079.60 Da        Isoelectric Point: 7.2746

>T100034 WP_124408130.1 NZ_CP027728:4768641-4768895 [Pseudomonas sp. R2-37-08W]
MKILFTPEGWDDYLWFQQNDKAGLKRINLLIKAIQRDPFEGVGKPEPLKHNLSGYWSRRITAEHRLVYGIEEDEVQILMC
RYHY

Download         Length: 255 bp

>T100034 NZ_CP027728:4768641-4768895 [Pseudomonas sp. R2-37-08W]
ATGAAAATACTCTTTACCCCTGAGGGCTGGGACGATTATCTGTGGTTTCAACAAAACGACAAGGCAGGGCTCAAGCGTAT
AAACCTGCTCATCAAAGCGATTCAAAGAGACCCATTTGAAGGTGTTGGAAAACCTGAGCCCCTCAAACACAACCTGAGCG
GCTACTGGTCTCGGCGAATCACAGCAGAGCATCGTTTGGTGTATGGCATCGAGGAGGATGAAGTACAGATCCTCATGTGC
CGTTATCACTACTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9599.97 Da        Isoelectric Point: 6.7262

>AT100034 WP_124368289.1 NZ_CP027728:4768390-4768644 [Pseudomonas sp. R2-37-08W]
METINYTHARAHLSETMDRVNEDHIPLLLTRQKGEPVVMISLSEFNALEETAYLLRSPKNAERLINSVNSLRAGKAKPRQ
LIEE

Download         Length: 255 bp

>AT100034 NZ_CP027728:4768390-4768644 [Pseudomonas sp. R2-37-08W]
ATGGAAACTATCAACTACACCCATGCGCGTGCTCACCTGTCCGAAACCATGGACCGCGTTAATGAAGATCACATTCCACT
GCTCCTGACCCGACAAAAAGGCGAACCGGTGGTGATGATCTCGTTGTCAGAATTCAATGCTCTCGAGGAAACAGCCTATT
TATTGCGCTCGCCAAAAAATGCCGAACGCCTCATCAACTCAGTCAACAGCTTACGAGCCGGCAAAGCCAAGCCAAGGCAG
TTGATTGAAGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References