Detailed information of TA system TA100034

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relE-yefM/YoeB-YefM
• Location: 4768390..4768895
• Replicon: chromosome
• Accession: NZ_CP027728
• Organism: Pseudomonas sp. R2-37-08W

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: C4J93_RS22005
• Protein ID: WP_124408130.1
• Coordinates: 4768641..4768895 (+)
• Length: 85 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: -
• Locus tag: C4J93_RS22000
• Protein ID: WP_124368289.1
• Coordinates: 4768390..4768644 (+)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C4J93_RS21980	4763598..4763804	+	207	WP_124368285.1	hypothetical protein	-
C4J93_RS21985	4763918..4765810	+	1893	WP_124430453.1	alkaline phosphatase family protein	-
C4J93_RS21990	4765928..4766941	+	1014	WP_124430454.1	diguanylate cyclase	-
C4J93_RS21995	4767047..4768296	+	1250	Protein_4256	aspartate aminotransferase family protein	-
C4J93_RS22000	4768390..4768644	+	255	WP_124368289.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
C4J93_RS22005	4768641..4768895	+	255	WP_124408130.1	Txe/YoeB family addiction module toxin	Toxin
C4J93_RS22010	4768998..4769714	+	717	WP_124430455.1	hypothetical protein	-
C4J93_RS22015	4769724..4770845	-	1122	WP_124430456.1	aminotransferase class V-fold PLP-dependent enzyme	-
C4J93_RS22020	4770847..4772049	-	1203	WP_124430457.1	MFS transporter	-
C4J93_RS22025	4772049..4773299	-	1251	WP_124364335.1	ATP-grasp domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (5-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-73)

Sequences

Toxin

Protein

• Length: 85 a.a.
• Molecular weight: 10079.60 Da
• Isoelectric Point: 7.2746

>T100034 WP_124408130.1 NZ_CP027728:4768641-4768895 [Pseudomonas sp. R2-37-08W]
MKILFTPEGWDDYLWFQQNDKAGLKRINLLIKAIQRDPFEGVGKPEPLKHNLSGYWSRRITAEHRLVYGIEEDEVQILMC
RYHY

Nucleotide

• Length: 255 bp

>T100034 NZ_CP027728:4768641-4768895 [Pseudomonas sp. R2-37-08W]
ATGAAAATACTCTTTACCCCTGAGGGCTGGGACGATTATCTGTGGTTTCAACAAAACGACAAGGCAGGGCTCAAGCGTAT
AAACCTGCTCATCAAAGCGATTCAAAGAGACCCATTTGAAGGTGTTGGAAAACCTGAGCCCCTCAAACACAACCTGAGCG
GCTACTGGTCTCGGCGAATCACAGCAGAGCATCGTTTGGTGTATGGCATCGAGGAGGATGAAGTACAGATCCTCATGTGC
CGTTATCACTACTGA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9599.97 Da
• Isoelectric Point: 6.7262

>AT100034 WP_124368289.1 NZ_CP027728:4768390-4768644 [Pseudomonas sp. R2-37-08W]
METINYTHARAHLSETMDRVNEDHIPLLLTRQKGEPVVMISLSEFNALEETAYLLRSPKNAERLINSVNSLRAGKAKPRQ
LIEE

Nucleotide

• Length: 255 bp

>AT100034 NZ_CP027728:4768390-4768644 [Pseudomonas sp. R2-37-08W]
ATGGAAACTATCAACTACACCCATGCGCGTGCTCACCTGTCCGAAACCATGGACCGCGTTAATGAAGATCACATTCCACT
GCTCCTGACCCGACAAAAAGGCGAACCGGTGGTGATGATCTCGTTGTCAGAATTCAATGCTCTCGAGGAAACAGCCTATT
TATTGCGCTCGCCAAAAAATGCCGAACGCCTCATCAACTCAGTCAACAGCTTACGAGCCGGCAAAGCCAAGCCAAGGCAG
TTGATTGAAGAATGA