Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 3699452..3700668 Replicon chromosome
Accession NZ_CP027728
Organism Pseudomonas sp. R2-37-08W

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag C4J93_RS17055 Protein ID WP_124367567.1
Coordinates 3700096..3700668 (+) Length 191 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag C4J93_RS17050 Protein ID WP_124371210.1
Coordinates 3699452..3700009 (+) Length 186 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4J93_RS17020 3694652..3695215 - 564 WP_177413552.1 adenine phosphoribosyltransferase -
C4J93_RS17025 3695190..3696160 - 971 Protein_3304 cysteine synthase family protein -
C4J93_RS17035 3696651..3697727 + 1077 WP_124371208.1 aldo/keto reductase -
C4J93_RS17040 3697801..3698037 + 237 WP_124363466.1 hypothetical protein -
C4J93_RS17045 3698077..3698907 + 831 WP_124430007.1 acid phosphatase -
C4J93_RS17050 3699452..3700009 + 558 WP_124371210.1 helix-turn-helix domain-containing protein Antitoxin
C4J93_RS17055 3700096..3700668 + 573 WP_124367567.1 HD domain-containing protein Toxin
C4J93_RS17060 3700675..3701097 - 423 WP_124430008.1 RidA family protein -
C4J93_RS17065 3701109..3702692 - 1584 WP_124430009.1 FAD-dependent oxidoreductase -
C4J93_RS17070 3702704..3703627 - 924 WP_124430010.1 ABC transporter substrate-binding protein -
C4J93_RS17075 3703646..3704419 - 774 WP_124430011.1 amino acid ABC transporter ATP-binding protein -
C4J93_RS17080 3704412..3705383 - 972 WP_124430012.1 amino acid ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HD domain

(16-173)

Antitoxin

Cro/C1-type helix-turn-helix domain

(12-62)


Sequences

Toxin        


Download         Length: 191 a.a.        Molecular weight: 21316.35 Da        Isoelectric Point: 4.9538

>T100032 WP_124367567.1 NZ_CP027728:3700096-3700668 [Pseudomonas sp. R2-37-08W]
MDFEKIKGRLDFLREAEKLKDVLRSAHTASGRTESTAEHSWRLCLMAMVFADQLPGLDLLKILKMCVIHDLGEAINGDIP
AVSQAAFPNKGEQERRDLLQLTQALDGPLKSQILTLWDDYENALSPEAKAVKAMDKLETLLQHTQGLNPPDFDYAFNLAY
GKKHTDAEPLFEALRALIDRATQERLDAAQ

Download         Length: 573 bp

>T100032 NZ_CP027728:3700096-3700668 [Pseudomonas sp. R2-37-08W]
ATGGACTTCGAAAAAATCAAAGGCCGCCTCGACTTTCTGCGCGAAGCCGAGAAACTCAAGGACGTGCTCAGAAGCGCCCA
CACCGCTTCGGGACGCACGGAAAGTACCGCCGAACACAGTTGGCGCCTGTGCCTGATGGCGATGGTGTTCGCCGATCAAC
TGCCCGGCCTGGACCTGCTTAAAATCCTCAAGATGTGCGTGATCCATGACTTGGGCGAAGCCATTAACGGTGACATTCCA
GCAGTCAGCCAGGCGGCGTTTCCCAACAAGGGCGAGCAGGAGCGGCGCGACCTGCTGCAGTTGACCCAAGCCCTGGATGG
GCCCCTGAAAAGCCAGATTCTGACGCTGTGGGATGACTACGAGAACGCACTGTCGCCGGAAGCCAAAGCCGTCAAGGCGA
TGGACAAGCTGGAGACCTTGCTGCAGCACACCCAGGGCCTCAACCCGCCGGATTTCGATTACGCTTTCAACCTGGCATAC
GGCAAGAAACATACGGATGCCGAGCCCTTATTCGAGGCGCTGCGTGCGCTGATCGACCGCGCTACTCAGGAACGCCTCGA
CGCCGCGCAGTGA

Antitoxin


Download         Length: 186 a.a.        Molecular weight: 20517.54 Da        Isoelectric Point: 10.3561

>AT100032 WP_124371210.1 NZ_CP027728:3699452-3700009 [Pseudomonas sp. R2-37-08W]
MPALILQPAIPGIALRRWRLLHRVKQTHAAQMFNVNQSTLSRWENGLQAMDAAAHQQLERLLSARLDTAADQALAGLVRD
SSRAVHLVCDLTHRLLACSPSRAAQFSRPLVDLMGQSLWRYATAEIRQVEAALDHTGWRENQAPPALQFSTGSNDSSLVP
IRPSLCRWTRLILSDGSAARLVETL

Download         Length: 558 bp

>AT100032 NZ_CP027728:3699452-3700009 [Pseudomonas sp. R2-37-08W]
ATGCCCGCCCTGATACTCCAGCCCGCCATTCCGGGCATTGCGCTGCGCCGATGGCGCCTGTTACACCGCGTCAAGCAAAC
CCATGCCGCACAGATGTTCAACGTAAACCAATCGACGCTGTCCCGCTGGGAGAATGGCCTGCAAGCCATGGACGCTGCCG
CGCACCAACAGCTGGAACGGTTGCTGTCCGCTCGGCTTGACACCGCAGCTGATCAGGCCCTGGCTGGGCTGGTCAGAGAC
AGCTCGCGCGCCGTACACCTGGTGTGCGACCTGACGCACCGCCTCCTGGCCTGTTCGCCCTCCCGCGCCGCCCAGTTCAG
CCGCCCATTGGTCGACTTGATGGGCCAATCGCTGTGGCGTTATGCGACAGCGGAAATCCGCCAGGTCGAAGCCGCGTTGG
ATCACACCGGCTGGCGCGAGAACCAAGCGCCGCCGGCGCTTCAATTCAGCACCGGCAGCAACGACTCCAGCCTCGTGCCG
ATCCGCCCGAGCCTGTGTCGCTGGACACGCCTGATCCTCAGCGATGGCAGCGCCGCGCGTCTGGTCGAGACGCTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References