Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/RHH(antitoxin)
Location 2404909..2405462 Replicon chromosome
Accession NZ_CP027727
Organism Pseudomonas sp. R5-89-07

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag C4J94_RS11145 Protein ID WP_124386201.1
Coordinates 2405169..2405462 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag C4J94_RS11140 Protein ID WP_124386200.1
Coordinates 2404909..2405181 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4J94_RS11115 2400670..2401176 + 507 WP_124386195.1 GNAT family N-acetyltransferase -
C4J94_RS11120 2401165..2402124 - 960 WP_124386196.1 GlxA family transcriptional regulator -
C4J94_RS11125 2402298..2402927 + 630 WP_124386197.1 TetR/AcrR family transcriptional regulator -
C4J94_RS11130 2402924..2403601 + 678 WP_124386198.1 type 1 glutamine amidotransferase domain-containing protein -
C4J94_RS11135 2403680..2404804 + 1125 WP_124386199.1 alkene reductase -
C4J94_RS11140 2404909..2405181 + 273 WP_124386200.1 CopG family ribbon-helix-helix protein Antitoxin
C4J94_RS11145 2405169..2405462 + 294 WP_124386201.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C4J94_RS11150 2405467..2406465 - 999 WP_124386202.1 NAD(P)H-quinone oxidoreductase -
C4J94_RS11155 2406462..2407691 - 1230 WP_124386203.1 YbfB/YjiJ family MFS transporter -
C4J94_RS11160 2407800..2408675 + 876 WP_124386204.1 LysR family transcriptional regulator -
C4J94_RS11165 2408752..2409138 + 387 WP_124386205.1 DoxX family protein -
C4J94_RS11170 2409268..2410086 - 819 WP_124386206.1 alpha/beta hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-95)

Antitoxin

Ribbon-helix-helix protein, CopG

(3-40)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10906.59 Da        Isoelectric Point: 7.1645

>T100025 WP_124386201.1 NZ_CP027727:2405169-2405462 [Pseudomonas sp. R5-89-07]
VPRLIITATALTGLERCRHLLMEKDPQVARRAAQTINTQLLRLESDPDVGRPYEPSPELRELVIAFGDAGYVALYRFIPA
DSAVMVLAFRHQREAGY

Download         Length: 294 bp

>T100025 NZ_CP027727:2405169-2405462 [Pseudomonas sp. R5-89-07]
GTGCCACGACTGATCATCACCGCAACGGCGCTGACAGGGTTGGAGCGCTGTCGGCATTTACTGATGGAGAAAGACCCGCA
GGTCGCCCGCAGGGCCGCCCAGACGATCAACACGCAACTGTTGCGTCTGGAGTCCGACCCTGATGTCGGCCGGCCCTATG
AGCCATCCCCCGAGTTGCGTGAGCTTGTGATCGCCTTCGGGGACGCCGGTTATGTTGCGTTATACCGCTTCATCCCTGCG
GATTCAGCGGTTATGGTCTTGGCCTTTCGGCACCAACGGGAAGCCGGGTACTGA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10470.63 Da        Isoelectric Point: 6.0804

>AT100025 WP_124386200.1 NZ_CP027727:2404909-2405181 [Pseudomonas sp. R5-89-07]
MATSIKIDDELKQRIQLLAGARQRTAHWIMREALSQYVEREEARESFKQEALSSWKNYQETGLHLSGSETRAWLDTWGTE
HASEPPKCHD

Download         Length: 273 bp

>AT100025 NZ_CP027727:2404909-2405181 [Pseudomonas sp. R5-89-07]
ATGGCCACGTCTATAAAAATTGACGATGAGTTGAAGCAGCGCATTCAGCTGTTGGCGGGTGCGCGGCAGCGTACCGCGCA
TTGGATCATGCGCGAAGCGCTCTCTCAGTATGTCGAGCGGGAGGAGGCGCGTGAGAGCTTCAAGCAGGAAGCGTTGTCGT
CCTGGAAAAACTATCAGGAAACGGGGTTGCACTTGAGCGGCTCCGAGACGCGAGCCTGGCTTGATACCTGGGGTACGGAG
CACGCTTCGGAGCCGCCCAAGTGCCACGACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References