Detailed information of TA system TA100023

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RHH(antitoxin)
• Location: 1028529..1029070
• Replicon: chromosome
• Accession: NZ_CP027727
• Organism: Pseudomonas sp. R5-89-07

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: C4J94_RS04600
• Protein ID: WP_124388921.1
• Coordinates: 1028792..1029070 (+)
• Length: 93 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: C4J94_RS04595
• Protein ID: WP_124385109.1
• Coordinates: 1028529..1028795 (+)
• Length: 89 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C4J94_RS04580	1024469..1026769	-	2301	WP_124385106.1	TonB-dependent siderophore receptor	-
C4J94_RS04585	1026975..1027655	+	681	WP_124385107.1	Fe2+-dependent dioxygenase	-
C4J94_RS04590	1027657..1028439	+	783	WP_124385108.1	sel1 repeat family protein	-
C4J94_RS04595	1028529..1028795	+	267	WP_124385109.1	ribbon-helix-helix domain-containing protein	Antitoxin
C4J94_RS04600	1028792..1029070	+	279	WP_124388921.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
C4J94_RS04605	1029153..1030316	-	1164	WP_014716890.1	type III PLP-dependent enzyme	-
C4J94_RS04610	1030790..1031947	-	1158	WP_005784718.1	ABC transporter ATP-binding protein	-
C4J94_RS04615	1031944..1032597	-	654	WP_124385110.1	ABC transporter permease	-
C4J94_RS04620	1032609..1033505	-	897	WP_124385111.1	glycine betaine ABC transporter substrate-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-91)

Antitoxin

• Ribbon-helix-helix protein, CopG (9-45)

Sequences

Toxin

Protein

• Length: 93 a.a.
• Molecular weight: 10918.56 Da
• Isoelectric Point: 9.9728

>T100023 WP_124388921.1 NZ_CP027727:1028792-1029070 [Pseudomonas sp. R5-89-07]
MMELKWTNKALSDLARLYDFLSVVNRQAAARTVQSLSQAPSILLSNPRIGERIEEFSPRDVRRVLVGHYEMRYEIQQSTL
YVLRLWHVREDR

Nucleotide

• Length: 279 bp

>T100023 NZ_CP027727:1028792-1029070 [Pseudomonas sp. R5-89-07]
CTGATGGAGCTGAAGTGGACAAACAAAGCTTTATCCGACTTGGCTCGATTGTATGACTTTCTCTCTGTAGTGAACCGCCA
AGCTGCCGCCCGCACCGTGCAGTCACTGTCCCAGGCGCCGAGTATATTGCTCAGTAATCCGCGTATCGGGGAAAGAATTG
AAGAGTTTTCGCCGCGAGACGTAAGAAGAGTTTTGGTCGGCCATTACGAAATGCGCTACGAAATTCAACAGTCCACACTT
TATGTTTTACGGTTATGGCACGTTCGCGAGGACCGCTGA

Antitoxin

Protein

• Length: 89 a.a.
• Molecular weight: 9683.95 Da
• Isoelectric Point: 4.7497

>AT100023 WP_124385109.1 NZ_CP027727:1028529-1028795 [Pseudomonas sp. R5-89-07]
MGADTKVMTAHIPTALAQKVDQMAARMDRSRGWVVKQALADWVDQEEERSRLTLEAMADVDAGRVIDHQAVQAWADSLGT
DSPLPVPR

Nucleotide

• Length: 267 bp

>AT100023 NZ_CP027727:1028529-1028795 [Pseudomonas sp. R5-89-07]
ATGGGTGCCGACACCAAAGTAATGACCGCTCACATTCCCACCGCTCTCGCTCAGAAAGTCGACCAGATGGCCGCGCGCAT
GGACCGCTCGCGTGGATGGGTGGTGAAGCAAGCGCTTGCCGATTGGGTCGATCAAGAGGAAGAGCGCAGTCGTTTGACGC
TTGAGGCGATGGCGGATGTCGATGCGGGTCGCGTGATTGATCATCAGGCAGTGCAGGCTTGGGCTGACAGCCTGGGTACG
GACTCGCCGCTGCCGGTTCCGCGCTGA