100022

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 5200642..5202377 Replicon chromosome
Accession NZ_CP027726
Organism Pseudomonas orientalis strain R4-35-08

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag C4J95_RS23880 Protein ID WP_124359983.1
Coordinates 5200642..5201286 (+) Length 215 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag C4J95_RS23885 Protein ID WP_124359984.1
Coordinates 5201283..5202377 (+) Length 365 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4J95_RS23845 5195944..5196600 + 657 WP_124359978.1 DedA family protein -
C4J95_RS23850 5196607..5197422 + 816 WP_124359979.1 zinc-dependent peptidase -
C4J95_RS23855 5197532..5198059 + 528 WP_005791810.1 inorganic diphosphatase -
C4J95_RS23860 5198271..5199041 + 771 WP_124359980.1 helix-turn-helix transcriptional regulator -
C4J95_RS23870 5199335..5199571 - 237 WP_124359981.1 hypothetical protein -
C4J95_RS23875 5200073..5200645 + 573 WP_124359982.1 DUF4433 domain-containing protein -
C4J95_RS23880 5200642..5201286 + 645 WP_124359983.1 DUF4433 domain-containing protein Toxin
C4J95_RS23885 5201283..5202377 + 1095 WP_124359984.1 macro domain-containing protein Antitoxin
C4J95_RS23890 5202426..5202824 - 399 WP_124359985.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
C4J95_RS23895 5202814..5203578 - 765 WP_124359986.1 type IV toxin-antitoxin system AbiEi family antitoxin -
C4J95_RS23900 5203786..5204418 + 633 WP_124359987.1 hydrolase -
C4J95_RS23905 5204555..5205694 + 1140 WP_124359988.1 Fic family protein -
C4J95_RS23910 5205769..5206011 + 243 WP_003176346.1 exodeoxyribonuclease VII small subunit -
C4J95_RS23915 5206008..5206895 + 888 WP_124359989.1 polyprenyl synthetase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(14-213)

Antitoxin

Macro domain

(18-130)


Sequences

Toxin        


Download         Length: 215 a.a.        Molecular weight: 24887.42 Da        Isoelectric Point: 6.4028

>T100022 WP_124359983.1 NZ_CP027726:5200642-5201286 [Pseudomonas orientalis]
MIYNNLNPEKALIWRIVHRDNLPWILDNGLHCASSEVQAAQYVNIGNVDLIDKRRTRCVPIAPSGFLSDYVPFYFTPFSV
MMKNIHSGWSVQQRNNDEIVILVSSLHRVAELGLPFVFTNAHAYPDWTDYYSDLADLHEIDWSILQRRDFKRDPDDPRKM
ERYQAEALIHHHLPITGLLGIMCYTDAMKERIEQDVAARGLTLPVYARPGWYFP

Download         Length: 645 bp

>T100022 NZ_CP027726:5200642-5201286 [Pseudomonas orientalis]
ATGATTTATAACAACCTGAATCCTGAAAAAGCTCTGATCTGGCGAATCGTTCATCGCGACAATCTGCCCTGGATTCTGGA
CAACGGCCTGCACTGCGCCAGCTCAGAGGTGCAGGCTGCGCAATATGTGAACATAGGCAATGTAGATTTAATCGACAAAC
GCCGCACGCGCTGTGTCCCCATCGCTCCTTCAGGCTTTTTGTCAGACTACGTTCCCTTCTATTTCACACCCTTCTCTGTG
ATGATGAAAAATATTCACTCCGGCTGGAGCGTTCAGCAACGCAACAATGACGAGATCGTGATTCTGGTCTCCAGCCTCCA
CCGCGTCGCCGAGCTTGGCCTACCGTTCGTCTTCACAAATGCACATGCGTACCCGGATTGGACAGACTATTACAGCGACC
TGGCGGATCTCCACGAGATCGATTGGTCAATCCTTCAACGGCGTGACTTCAAACGTGACCCCGATGACCCTCGCAAAATG
GAGCGTTATCAGGCTGAAGCGCTGATTCACCACCACTTACCGATTACAGGACTCCTTGGCATCATGTGTTACACCGATGC
GATGAAAGAACGCATAGAGCAGGACGTCGCCGCAAGAGGCCTGACGTTGCCTGTATATGCTCGTCCGGGATGGTATTTCC
CATGA

Antitoxin


Download         Length: 365 a.a.        Molecular weight: 41191.20 Da        Isoelectric Point: 6.4189

>AT100022 WP_124359984.1 NZ_CP027726:5201283-5202377 [Pseudomonas orientalis]
MIRFTQGNLLQANTEVLVNTVNTVGVMGKGIALMFKERFAENYRLYAAACKAGEVETGKVHVTAVNELDGPRWIVNFPTK
RHWRSPSQMAWITEGLHDLRRFLIENHVKSVAVPPLGAGNGGLKWLDVREQIEDVLSDLDVDVLVFEPSNQYLNVAKRSG
VEQLTPARALIAELVRRYWVLGMECSLLEIQKLAWFLERAIEKRPGLKNPLDLKFVAHKYGPYANRLEHLLNNLDGSYLH
CDKRISDAENSDVIWFDQDRRAFLQTYLRTEAKEYSQALELTAELIDGFESPFGMELLATVDWLLTQEDVAPTVPAVREA
LKRWDGGVAAAARKNKLFDDQALDIALKRLTSSSFSHQMASCHI

Download         Length: 1095 bp

>AT100022 NZ_CP027726:5201283-5202377 [Pseudomonas orientalis]
ATGATCAGATTCACCCAGGGCAACCTTCTGCAAGCCAACACCGAAGTCCTCGTCAATACGGTGAATACCGTGGGCGTCAT
GGGCAAGGGCATCGCGCTGATGTTCAAAGAGCGTTTTGCAGAAAACTATCGCCTGTACGCTGCTGCCTGTAAAGCTGGCG
AGGTAGAGACCGGAAAAGTGCACGTAACTGCGGTCAACGAACTGGACGGTCCTCGCTGGATCGTTAACTTCCCGACCAAA
CGTCACTGGCGATCACCATCGCAGATGGCATGGATAACCGAAGGCCTGCACGACCTCCGTCGTTTTCTGATTGAAAACCA
TGTGAAGTCAGTGGCGGTTCCTCCGTTAGGGGCCGGTAACGGTGGTCTGAAATGGCTGGACGTTCGCGAACAGATCGAGG
ATGTCTTGAGCGATCTGGATGTCGATGTGTTGGTTTTTGAGCCATCCAATCAGTATCTGAATGTCGCCAAACGCAGCGGC
GTAGAACAGCTTACGCCTGCGCGCGCGCTCATTGCGGAACTGGTTCGACGCTACTGGGTGTTAGGTATGGAATGCAGCCT
GCTTGAGATTCAGAAACTGGCTTGGTTCCTGGAGCGCGCAATTGAGAAGCGGCCAGGCCTCAAAAACCCACTGGACCTTA
AGTTTGTCGCTCATAAGTACGGGCCGTATGCCAACCGGTTGGAACACCTGCTTAACAATCTGGACGGTAGTTATCTGCAT
TGCGATAAGCGAATCAGCGATGCGGAAAACAGTGATGTGATCTGGTTTGACCAAGACCGCAGAGCCTTTCTACAAACCTA
TCTCAGGACAGAGGCCAAGGAATATTCCCAGGCCTTGGAGCTTACCGCGGAGTTGATCGATGGCTTTGAATCACCCTTCG
GCATGGAGCTATTGGCAACAGTTGACTGGCTGCTGACCCAGGAAGATGTAGCCCCAACCGTTCCGGCTGTACGTGAGGCA
CTGAAACGATGGGATGGCGGTGTCGCTGCAGCCGCTCGCAAAAACAAGCTGTTTGACGATCAAGCACTTGATATTGCGCT
TAAACGGCTCACTTCCAGCAGCTTCAGCCATCAAATGGCTTCCTGTCATATATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References