Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | PP_4151-4152/excise(antitoxin) |
Location | 4845367..4846409 | Replicon | chromosome |
Accession | NZ_CP027726 | ||
Organism | Pseudomonas orientalis strain R4-35-08 |
Toxin (Protein)
Gene name | PP_4152 | Uniprot ID | - |
Locus tag | C4J95_RS22230 | Protein ID | WP_124359747.1 |
Coordinates | 4845367..4845942 (-) | Length | 192 a.a. |
Antitoxin (Protein)
Gene name | PP_4151 | Uniprot ID | - |
Locus tag | C4J95_RS22235 | Protein ID | WP_124359748.1 |
Coordinates | 4845939..4846409 (-) | Length | 157 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
C4J95_RS22190 | 4840969..4841292 | + | 324 | WP_124359740.1 | hypothetical protein | - |
C4J95_RS22195 | 4841390..4841764 | + | 375 | WP_124359741.1 | cupin domain-containing protein | - |
C4J95_RS22200 | 4841842..4842312 | + | 471 | WP_124359742.1 | hypothetical protein | - |
C4J95_RS22205 | 4842315..4842599 | - | 285 | WP_065885099.1 | hypothetical protein | - |
C4J95_RS22210 | 4842630..4843526 | - | 897 | WP_124359743.1 | hypothetical protein | - |
C4J95_RS22215 | 4843737..4844066 | + | 330 | WP_124359744.1 | hypothetical protein | - |
C4J95_RS22220 | 4844074..4844709 | - | 636 | WP_124359745.1 | LysE family translocator | - |
C4J95_RS22225 | 4844867..4845238 | + | 372 | WP_124359746.1 | PH domain-containing protein | - |
C4J95_RS22230 | 4845367..4845942 | - | 576 | WP_124359747.1 | PIN domain-containing protein | Toxin |
C4J95_RS22235 | 4845939..4846409 | - | 471 | WP_124359748.1 | helix-turn-helix domain-containing protein | Antitoxin |
C4J95_RS22240 | 4846594..4847742 | + | 1149 | WP_124359749.1 | S-type pyocin domain-containing protein | - |
C4J95_RS22245 | 4847750..4848007 | + | 258 | WP_124359750.1 | colicin transporter | - |
C4J95_RS22250 | 4848118..4849032 | - | 915 | WP_124359751.1 | LysR family transcriptional regulator | - |
C4J95_RS22255 | 4849117..4849914 | + | 798 | WP_124359752.1 | NAD(P)H-dependent oxidoreductase | - |
C4J95_RS22260 | 4849964..4850338 | - | 375 | WP_124359753.1 | cytochrome c family protein | - |
C4J95_RS22265 | 4850532..4850912 | + | 381 | WP_124359754.1 | response regulator | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 192 a.a. Molecular weight: 21703.99 Da Isoelectric Point: 4.8632
>T100021 WP_124359747.1 NZ_CP027726:c4845942-4845367 [Pseudomonas orientalis]
MRCSPFTAVYDACVLYPAALRDLLMWLGLSGLYRARWTRQIHEEWKRNVFRNRPDLTPDQVDKISALMDQAIPDALVTGY
EDLCSSLDLPDPDDRHVLAAAIRSKAEVIVTFNLKDFPAHVLAAYDIESMHPDDFISDLWDLDQAAVLAAVQRQRRALAR
PPMNGEGYLEMLMRQGLVQTSKLLGPYEVML
MRCSPFTAVYDACVLYPAALRDLLMWLGLSGLYRARWTRQIHEEWKRNVFRNRPDLTPDQVDKISALMDQAIPDALVTGY
EDLCSSLDLPDPDDRHVLAAAIRSKAEVIVTFNLKDFPAHVLAAYDIESMHPDDFISDLWDLDQAAVLAAVQRQRRALAR
PPMNGEGYLEMLMRQGLVQTSKLLGPYEVML
Download Length: 576 bp
>T100021 NZ_CP027726:c4845942-4845367 [Pseudomonas orientalis]
ATGAGGTGTTCTCCGTTCACTGCGGTTTACGACGCCTGTGTCCTCTACCCTGCGGCTCTCAGGGATTTGTTGATGTGGCT
TGGTTTATCCGGGCTGTACCGAGCTCGATGGACCAGACAGATTCATGAGGAGTGGAAGCGTAACGTATTCAGGAACCGAC
CTGATCTAACTCCCGACCAGGTAGATAAAATATCGGCGTTGATGGACCAGGCCATACCGGACGCGTTGGTGACGGGATAC
GAAGATTTGTGTTCAAGTTTGGATTTGCCTGATCCGGATGATCGTCACGTATTGGCCGCGGCAATCCGGAGTAAGGCGGA
AGTCATCGTGACCTTTAATTTGAAAGACTTTCCAGCGCATGTGCTGGCGGCTTATGACATAGAATCGATGCATCCCGACG
ACTTTATCTCGGACCTTTGGGATTTGGATCAAGCTGCCGTATTGGCTGCAGTGCAGAGGCAAAGGCGCGCACTAGCGAGG
CCGCCGATGAATGGGGAAGGGTATCTCGAGATGTTGATGCGGCAGGGGCTGGTGCAGACCAGTAAGCTGCTTGGGCCCTA
TGAAGTAATGTTGTAG
ATGAGGTGTTCTCCGTTCACTGCGGTTTACGACGCCTGTGTCCTCTACCCTGCGGCTCTCAGGGATTTGTTGATGTGGCT
TGGTTTATCCGGGCTGTACCGAGCTCGATGGACCAGACAGATTCATGAGGAGTGGAAGCGTAACGTATTCAGGAACCGAC
CTGATCTAACTCCCGACCAGGTAGATAAAATATCGGCGTTGATGGACCAGGCCATACCGGACGCGTTGGTGACGGGATAC
GAAGATTTGTGTTCAAGTTTGGATTTGCCTGATCCGGATGATCGTCACGTATTGGCCGCGGCAATCCGGAGTAAGGCGGA
AGTCATCGTGACCTTTAATTTGAAAGACTTTCCAGCGCATGTGCTGGCGGCTTATGACATAGAATCGATGCATCCCGACG
ACTTTATCTCGGACCTTTGGGATTTGGATCAAGCTGCCGTATTGGCTGCAGTGCAGAGGCAAAGGCGCGCACTAGCGAGG
CCGCCGATGAATGGGGAAGGGTATCTCGAGATGTTGATGCGGCAGGGGCTGGTGCAGACCAGTAAGCTGCTTGGGCCCTA
TGAAGTAATGTTGTAG
Antitoxin
Download Length: 157 a.a. Molecular weight: 17670.31 Da Isoelectric Point: 5.9433
>AT100021 WP_124359748.1 NZ_CP027726:c4846409-4845939 [Pseudomonas orientalis]
MITHHLPKTIPPLEKEVEAAVQGQRELASLLSTKFETQRIDIFDKEDKPHSLVLPTSALRLLVDILGELALGNAVKVVPV
HAELTSQEAADLLNVSRPHLVKMLEEGAIPFTKTGRHRRIRFSDLMAFKQRRDEESQEAMEELVRQTRELGLGYDE
MITHHLPKTIPPLEKEVEAAVQGQRELASLLSTKFETQRIDIFDKEDKPHSLVLPTSALRLLVDILGELALGNAVKVVPV
HAELTSQEAADLLNVSRPHLVKMLEEGAIPFTKTGRHRRIRFSDLMAFKQRRDEESQEAMEELVRQTRELGLGYDE
Download Length: 471 bp
>AT100021 NZ_CP027726:c4846409-4845939 [Pseudomonas orientalis]
ATGATCACCCATCACCTCCCTAAAACAATTCCTCCGCTGGAAAAGGAAGTCGAAGCCGCCGTGCAAGGCCAACGCGAACT
GGCCTCGTTGCTATCGACCAAATTCGAAACCCAACGCATCGATATCTTCGACAAAGAAGACAAACCCCACTCCCTTGTAC
TCCCCACATCCGCGCTACGTCTGCTGGTTGATATTTTGGGTGAGCTGGCGCTGGGCAATGCCGTCAAGGTTGTACCCGTC
CATGCCGAATTGACCTCCCAGGAAGCTGCCGACCTGCTTAACGTTTCACGCCCGCATCTGGTCAAGATGTTGGAAGAAGG
CGCAATTCCCTTTACGAAGACAGGTCGTCATCGGCGTATTCGGTTTTCGGATTTGATGGCGTTCAAGCAGCGCCGTGATG
AAGAAAGTCAGGAGGCGATGGAGGAATTGGTACGGCAGACGCGGGAGTTGGGATTGGGGTATGACGAATGA
ATGATCACCCATCACCTCCCTAAAACAATTCCTCCGCTGGAAAAGGAAGTCGAAGCCGCCGTGCAAGGCCAACGCGAACT
GGCCTCGTTGCTATCGACCAAATTCGAAACCCAACGCATCGATATCTTCGACAAAGAAGACAAACCCCACTCCCTTGTAC
TCCCCACATCCGCGCTACGTCTGCTGGTTGATATTTTGGGTGAGCTGGCGCTGGGCAATGCCGTCAAGGTTGTACCCGTC
CATGCCGAATTGACCTCCCAGGAAGCTGCCGACCTGCTTAACGTTTCACGCCCGCATCTGGTCAAGATGTTGGAAGAAGG
CGCAATTCCCTTTACGAAGACAGGTCGTCATCGGCGTATTCGGTTTTCGGATTTGATGGCGTTCAAGCAGCGCCGTGATG
AAGAAAGTCAGGAGGCGATGGAGGAATTGGTACGGCAGACGCGGGAGTTGGGATTGGGGTATGACGAATGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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