Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 4845367..4846409 Replicon chromosome
Accession NZ_CP027726
Organism Pseudomonas orientalis strain R4-35-08

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag C4J95_RS22230 Protein ID WP_124359747.1
Coordinates 4845367..4845942 (-) Length 192 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID -
Locus tag C4J95_RS22235 Protein ID WP_124359748.1
Coordinates 4845939..4846409 (-) Length 157 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4J95_RS22190 4840969..4841292 + 324 WP_124359740.1 hypothetical protein -
C4J95_RS22195 4841390..4841764 + 375 WP_124359741.1 cupin domain-containing protein -
C4J95_RS22200 4841842..4842312 + 471 WP_124359742.1 hypothetical protein -
C4J95_RS22205 4842315..4842599 - 285 WP_065885099.1 hypothetical protein -
C4J95_RS22210 4842630..4843526 - 897 WP_124359743.1 hypothetical protein -
C4J95_RS22215 4843737..4844066 + 330 WP_124359744.1 hypothetical protein -
C4J95_RS22220 4844074..4844709 - 636 WP_124359745.1 LysE family translocator -
C4J95_RS22225 4844867..4845238 + 372 WP_124359746.1 PH domain-containing protein -
C4J95_RS22230 4845367..4845942 - 576 WP_124359747.1 PIN domain-containing protein Toxin
C4J95_RS22235 4845939..4846409 - 471 WP_124359748.1 helix-turn-helix domain-containing protein Antitoxin
C4J95_RS22240 4846594..4847742 + 1149 WP_124359749.1 S-type pyocin domain-containing protein -
C4J95_RS22245 4847750..4848007 + 258 WP_124359750.1 colicin transporter -
C4J95_RS22250 4848118..4849032 - 915 WP_124359751.1 LysR family transcriptional regulator -
C4J95_RS22255 4849117..4849914 + 798 WP_124359752.1 NAD(P)H-dependent oxidoreductase -
C4J95_RS22260 4849964..4850338 - 375 WP_124359753.1 cytochrome c family protein -
C4J95_RS22265 4850532..4850912 + 381 WP_124359754.1 response regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(9-115)

Antitoxin

Helix-turn-helix domain, group 17

(84-132)


Sequences

Toxin        


Download         Length: 192 a.a.        Molecular weight: 21703.99 Da        Isoelectric Point: 4.8632

>T100021 WP_124359747.1 NZ_CP027726:c4845942-4845367 [Pseudomonas orientalis]
MRCSPFTAVYDACVLYPAALRDLLMWLGLSGLYRARWTRQIHEEWKRNVFRNRPDLTPDQVDKISALMDQAIPDALVTGY
EDLCSSLDLPDPDDRHVLAAAIRSKAEVIVTFNLKDFPAHVLAAYDIESMHPDDFISDLWDLDQAAVLAAVQRQRRALAR
PPMNGEGYLEMLMRQGLVQTSKLLGPYEVML

Download         Length: 576 bp

>T100021 NZ_CP027726:c4845942-4845367 [Pseudomonas orientalis]
ATGAGGTGTTCTCCGTTCACTGCGGTTTACGACGCCTGTGTCCTCTACCCTGCGGCTCTCAGGGATTTGTTGATGTGGCT
TGGTTTATCCGGGCTGTACCGAGCTCGATGGACCAGACAGATTCATGAGGAGTGGAAGCGTAACGTATTCAGGAACCGAC
CTGATCTAACTCCCGACCAGGTAGATAAAATATCGGCGTTGATGGACCAGGCCATACCGGACGCGTTGGTGACGGGATAC
GAAGATTTGTGTTCAAGTTTGGATTTGCCTGATCCGGATGATCGTCACGTATTGGCCGCGGCAATCCGGAGTAAGGCGGA
AGTCATCGTGACCTTTAATTTGAAAGACTTTCCAGCGCATGTGCTGGCGGCTTATGACATAGAATCGATGCATCCCGACG
ACTTTATCTCGGACCTTTGGGATTTGGATCAAGCTGCCGTATTGGCTGCAGTGCAGAGGCAAAGGCGCGCACTAGCGAGG
CCGCCGATGAATGGGGAAGGGTATCTCGAGATGTTGATGCGGCAGGGGCTGGTGCAGACCAGTAAGCTGCTTGGGCCCTA
TGAAGTAATGTTGTAG

Antitoxin


Download         Length: 157 a.a.        Molecular weight: 17670.31 Da        Isoelectric Point: 5.9433

>AT100021 WP_124359748.1 NZ_CP027726:c4846409-4845939 [Pseudomonas orientalis]
MITHHLPKTIPPLEKEVEAAVQGQRELASLLSTKFETQRIDIFDKEDKPHSLVLPTSALRLLVDILGELALGNAVKVVPV
HAELTSQEAADLLNVSRPHLVKMLEEGAIPFTKTGRHRRIRFSDLMAFKQRRDEESQEAMEELVRQTRELGLGYDE

Download         Length: 471 bp

>AT100021 NZ_CP027726:c4846409-4845939 [Pseudomonas orientalis]
ATGATCACCCATCACCTCCCTAAAACAATTCCTCCGCTGGAAAAGGAAGTCGAAGCCGCCGTGCAAGGCCAACGCGAACT
GGCCTCGTTGCTATCGACCAAATTCGAAACCCAACGCATCGATATCTTCGACAAAGAAGACAAACCCCACTCCCTTGTAC
TCCCCACATCCGCGCTACGTCTGCTGGTTGATATTTTGGGTGAGCTGGCGCTGGGCAATGCCGTCAAGGTTGTACCCGTC
CATGCCGAATTGACCTCCCAGGAAGCTGCCGACCTGCTTAACGTTTCACGCCCGCATCTGGTCAAGATGTTGGAAGAAGG
CGCAATTCCCTTTACGAAGACAGGTCGTCATCGGCGTATTCGGTTTTCGGATTTGATGGCGTTCAAGCAGCGCCGTGATG
AAGAAAGTCAGGAGGCGATGGAGGAATTGGTACGGCAGACGCGGGAGTTGGGATTGGGGTATGACGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References