100012

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 5224582..5226317 Replicon chromosome
Accession NZ_CP027725
Organism Pseudomonas orientalis strain R2-66-08W

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag C4J96_RS23835 Protein ID WP_124359983.1
Coordinates 5224582..5225226 (+) Length 215 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag C4J96_RS23840 Protein ID WP_124427678.1
Coordinates 5225223..5226317 (+) Length 365 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4J96_RS23800 5219884..5220540 + 657 WP_124359978.1 DedA family protein -
C4J96_RS23805 5220547..5221362 + 816 WP_124427676.1 zinc-dependent peptidase -
C4J96_RS23810 5221472..5221999 + 528 WP_005791810.1 inorganic diphosphatase -
C4J96_RS23815 5222211..5222981 + 771 WP_124425133.1 helix-turn-helix transcriptional regulator -
C4J96_RS23825 5223275..5223511 - 237 WP_124427677.1 hypothetical protein -
C4J96_RS23830 5224013..5224585 + 573 WP_124359982.1 DUF4433 domain-containing protein -
C4J96_RS23835 5224582..5225226 + 645 WP_124359983.1 DUF4433 domain-containing protein Toxin
C4J96_RS23840 5225223..5226317 + 1095 WP_124427678.1 macro domain-containing protein Antitoxin
C4J96_RS23845 5226366..5226764 - 399 WP_124427679.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
C4J96_RS23850 5226754..5227518 - 765 WP_124427680.1 type IV toxin-antitoxin system AbiEi family antitoxin -
C4J96_RS23855 5227726..5228358 + 633 WP_057703186.1 hydrolase -
C4J96_RS23860 5228495..5229634 + 1140 WP_124359988.1 Fic family protein -
C4J96_RS23865 5229709..5229951 + 243 WP_003176346.1 exodeoxyribonuclease VII small subunit -
C4J96_RS23870 5229948..5230835 + 888 WP_124427681.1 polyprenyl synthetase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(14-213)

Antitoxin

Macro domain

(18-130)


Sequences

Toxin        


Download         Length: 215 a.a.        Molecular weight: 24887.42 Da        Isoelectric Point: 6.4028

>T100012 WP_124359983.1 NZ_CP027725:5224582-5225226 [Pseudomonas orientalis]
MIYNNLNPEKALIWRIVHRDNLPWILDNGLHCASSEVQAAQYVNIGNVDLIDKRRTRCVPIAPSGFLSDYVPFYFTPFSV
MMKNIHSGWSVQQRNNDEIVILVSSLHRVAELGLPFVFTNAHAYPDWTDYYSDLADLHEIDWSILQRRDFKRDPDDPRKM
ERYQAEALIHHHLPITGLLGIMCYTDAMKERIEQDVAARGLTLPVYARPGWYFP

Download         Length: 645 bp

>T100012 NZ_CP027725:5224582-5225226 [Pseudomonas orientalis]
ATGATTTATAACAACCTGAATCCTGAAAAAGCTCTGATCTGGCGAATCGTTCATCGCGACAATCTGCCCTGGATTCTGGA
CAACGGCCTGCACTGCGCCAGCTCAGAGGTGCAGGCTGCGCAATATGTGAACATAGGCAATGTAGATTTAATCGACAAAC
GCCGCACGCGCTGTGTCCCCATCGCTCCTTCAGGCTTTTTGTCAGACTACGTTCCCTTCTATTTCACACCCTTCTCTGTG
ATGATGAAAAATATTCACTCCGGCTGGAGCGTTCAGCAACGCAACAATGACGAGATCGTGATTCTGGTCTCCAGCCTCCA
CCGCGTCGCCGAGCTTGGCCTACCGTTCGTCTTCACAAATGCACATGCGTACCCGGATTGGACAGACTATTACAGCGACC
TGGCGGATCTCCACGAGATCGATTGGTCAATCCTTCAACGGCGTGACTTCAAACGTGACCCCGATGACCCTCGCAAAATG
GAGCGTTATCAGGCTGAAGCGCTGATTCACCACCACTTACCGATTACAGGACTCCTTGGCATCATGTGTTACACCGATGC
GATGAAAGAACGCATAGAGCAGGACGTCGCCGCAAGAGGCCTGACGTTGCCTGTATATGCTCGTCCGGGATGGTATTTCC
CATGA

Antitoxin


Download         Length: 365 a.a.        Molecular weight: 41133.16 Da        Isoelectric Point: 6.5901

>AT100012 WP_124427678.1 NZ_CP027725:5225223-5226317 [Pseudomonas orientalis]
MIRFTQGNLLQANTEVLVNTVNTVGVMGKGIALMFKERFAENYRLYAAACKAGEVETGKVHVTAVNELDGPRWIVNFPTK
RHWRSPSQMAWITEGLHDLRRFLIENHVKSVAVPPLGAGNGGLKWLDVREQIEDVLSDLDVDVLVFEPSNQYLNVAKRSG
VEQLTPARALIAELVRRYWVLGMECSLLEIQKLAWFLERAIEKRPGLKNPLDLKFVAHKYGPYANRLEHLLNNLDGSYLH
CDKRISDAENSDVIWFDQDRRAFLQTYLRTEAKEYSQALELTAALIDGFESPFGMELLATVDWLLTQEDVAPTVPAVREA
LKRWDGGVAAAARKNKLFDDQALDIALKRLTSSSFSHQMASCHI

Download         Length: 1095 bp

>AT100012 NZ_CP027725:5225223-5226317 [Pseudomonas orientalis]
ATGATCAGATTCACCCAGGGCAACCTTCTGCAAGCCAACACCGAAGTCCTCGTCAATACGGTGAATACCGTGGGCGTCAT
GGGCAAGGGCATCGCGCTGATGTTCAAAGAGCGTTTTGCAGAAAACTATCGCCTGTACGCTGCTGCCTGTAAAGCTGGCG
AGGTAGAGACCGGAAAAGTGCACGTAACTGCGGTCAACGAACTGGACGGTCCTCGCTGGATCGTTAACTTCCCGACCAAA
CGTCACTGGCGATCACCATCGCAGATGGCATGGATAACCGAAGGCCTGCACGACCTCCGTCGTTTTCTGATTGAAAACCA
TGTGAAGTCAGTGGCGGTTCCTCCGTTAGGGGCCGGTAACGGTGGTCTGAAATGGCTGGACGTTCGCGAACAGATCGAGG
ATGTCTTGAGCGATCTGGATGTCGATGTGTTGGTTTTTGAGCCATCCAATCAGTATCTGAATGTCGCCAAACGCAGCGGC
GTAGAACAGCTTACGCCTGCGCGCGCGCTCATTGCGGAACTGGTTCGACGCTACTGGGTGTTAGGTATGGAATGCAGCCT
GCTTGAGATTCAGAAACTGGCTTGGTTCCTGGAGCGCGCAATTGAGAAGCGGCCAGGCCTCAAAAACCCACTGGACCTTA
AGTTTGTCGCTCATAAGTACGGGCCGTATGCCAACCGGTTGGAACACCTGCTTAACAATCTGGACGGTAGTTATCTGCAT
TGCGATAAGCGAATCAGCGATGCGGAAAACAGTGATGTGATCTGGTTTGACCAAGACCGCAGAGCCTTTCTACAAACCTA
TCTCAGGACAGAGGCCAAGGAATATTCCCAGGCCTTGGAGCTTACCGCGGCGTTGATCGATGGCTTTGAATCACCCTTCG
GCATGGAGCTATTGGCAACAGTTGACTGGCTGCTGACCCAGGAAGATGTAGCCCCAACCGTTCCGGCTGTACGTGAGGCA
CTGAAACGATGGGATGGCGGTGTCGCTGCAGCCGCTCGCAAAAACAAGCTGTTTGACGATCAAGCACTTGATATTGCGCT
TAAACGGCTCACTTCCAGCAGCTTCAGCCATCAAATGGCTTCCTGTCATATATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References