Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 4809455..4810497 Replicon chromosome
Accession NZ_CP027725
Organism Pseudomonas orientalis strain R2-66-08W

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag C4J96_RS21840 Protein ID WP_124427489.1
Coordinates 4809455..4810030 (-) Length 192 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID -
Locus tag C4J96_RS21845 Protein ID WP_124359748.1
Coordinates 4810027..4810497 (-) Length 157 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4J96_RS21800 4805057..4805380 + 324 WP_124427482.1 hypothetical protein -
C4J96_RS21805 4805478..4805852 + 375 WP_124427483.1 cupin domain-containing protein -
C4J96_RS21810 4805930..4806400 + 471 WP_124427484.1 hypothetical protein -
C4J96_RS21815 4806403..4806687 - 285 WP_124427485.1 hypothetical protein -
C4J96_RS21820 4806718..4807614 - 897 WP_124427486.1 hypothetical protein -
C4J96_RS21825 4807825..4808154 + 330 WP_124427487.1 hypothetical protein -
C4J96_RS21830 4808162..4808797 - 636 WP_124427488.1 LysE family translocator -
C4J96_RS21835 4808955..4809326 + 372 WP_048722821.1 PH domain-containing protein -
C4J96_RS21840 4809455..4810030 - 576 WP_124427489.1 PIN domain-containing protein Toxin
C4J96_RS21845 4810027..4810497 - 471 WP_124359748.1 helix-turn-helix domain-containing protein Antitoxin
C4J96_RS21850 4810682..4811829 + 1148 Protein_4193 S-type pyocin domain-containing protein -
C4J96_RS21855 4811837..4812094 + 258 WP_124359750.1 colicin transporter -
C4J96_RS21860 4812204..4813118 - 915 WP_124359751.1 LysR family transcriptional regulator -
C4J96_RS21865 4813203..4814000 + 798 WP_124427490.1 NAD(P)H-dependent oxidoreductase -
C4J96_RS21870 4814050..4814424 - 375 WP_124359753.1 cytochrome c family protein -
C4J96_RS21875 4814618..4814998 + 381 WP_057723990.1 response regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(9-115)

Antitoxin

Helix-turn-helix domain, group 17

(84-132)


Sequences

Toxin        


Download         Length: 192 a.a.        Molecular weight: 21680.01 Da        Isoelectric Point: 4.8632

>T100011 WP_124427489.1 NZ_CP027725:c4810030-4809455 [Pseudomonas orientalis]
MRCSPFTAVYDACVLYPAALRDLLMWLGLSGLYRARWTRQIHEEWKRNVLRNRPDLTPDQVDKISALMDQAIPDALVTGY
EDLCSSLDLPDPDDRHVLAAAIRSKAEVIVTFNLKDFPAHVLAAYDIEPMHPDDFISDLWDLDQAAVLAAVQRQRRALAR
PPMNGEGYLEMLMRQGLVQTSKLLGPYEVML

Download         Length: 576 bp

>T100011 NZ_CP027725:c4810030-4809455 [Pseudomonas orientalis]
ATGAGGTGTTCTCCGTTCACTGCGGTTTACGACGCCTGTGTCCTCTACCCTGCGGCTCTCAGGGATTTGTTGATGTGGCT
TGGTTTATCCGGGCTGTACCGAGCTCGATGGACCAGACAGATTCATGAGGAGTGGAAGCGTAACGTACTCAGGAACCGAC
CTGATCTAACTCCCGACCAGGTAGATAAAATATCGGCGTTGATGGACCAGGCCATACCGGACGCGTTGGTGACGGGATAC
GAAGATTTGTGTTCAAGTTTGGATTTGCCTGATCCGGATGATCGTCACGTATTGGCCGCGGCAATCCGGAGTAAGGCGGA
AGTCATCGTGACCTTTAATTTGAAAGACTTTCCAGCGCATGTGCTGGCGGCTTATGACATAGAACCGATGCATCCCGACG
ACTTTATCTCGGACCTTTGGGATTTGGATCAAGCTGCCGTATTGGCTGCAGTGCAGAGGCAAAGGCGCGCACTAGCGAGG
CCGCCGATGAATGGGGAAGGGTATCTCGAGATGTTGATGCGGCAGGGGCTGGTGCAGACCAGTAAGCTGCTTGGGCCCTA
TGAAGTAATGTTGTAG

Antitoxin


Download         Length: 157 a.a.        Molecular weight: 17670.31 Da        Isoelectric Point: 5.9433

>AT100011 WP_124359748.1 NZ_CP027725:c4810497-4810027 [Pseudomonas orientalis]
MITHHLPKTIPPLEKEVEAAVQGQRELASLLSTKFETQRIDIFDKEDKPHSLVLPTSALRLLVDILGELALGNAVKVVPV
HAELTSQEAADLLNVSRPHLVKMLEEGAIPFTKTGRHRRIRFSDLMAFKQRRDEESQEAMEELVRQTRELGLGYDE

Download         Length: 471 bp

>AT100011 NZ_CP027725:c4810497-4810027 [Pseudomonas orientalis]
ATGATCACCCATCACCTCCCTAAAACAATTCCTCCGCTGGAAAAGGAAGTCGAAGCCGCCGTGCAAGGCCAACGCGAACT
GGCCTCGTTGCTATCGACCAAATTCGAAACCCAACGCATCGATATCTTCGACAAAGAAGACAAACCCCACTCCCTTGTAC
TCCCCACATCCGCGCTACGTCTGCTGGTTGATATTTTGGGTGAGCTGGCGCTGGGCAATGCCGTCAAGGTTGTACCCGTC
CATGCCGAATTGACCTCCCAGGAAGCTGCCGACCTGCTTAACGTTTCACGCCCGCATCTGGTCAAGATGTTGGAAGAAGG
CGCAATTCCCTTTACGAAGACAGGTCGTCATCGGCGTATTCGGTTTTCGGATTTGATGGCGTTCAAGCAGCGCCGTGATG
AAGAAAGTCAGGAGGCGATGGAGGAATTGGTACGGCAGACGCGGGAGTTGGGATTGGGGTATGACGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References