Detailed information of TA system TA100005

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 3870724..3871324
• Replicon: chromosome
• Accession: NZ_CP027724
• Organism: Pseudomonas orientalis strain L1-3-08

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: C4J97_RS17255
• Protein ID: WP_124425635.1
• Coordinates: 3871001..3871324 (+)
• Length: 108 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: C4J97_RS17250
• Protein ID: WP_124424253.1
• Coordinates: 3870724..3871011 (+)
• Length: 96 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C4J97_RS17225	3865881..3867281	+	1401	WP_124424248.1	heavy metal sensor histidine kinase	-
C4J97_RS17230	3867289..3867747	-	459	WP_124424249.1	RcnB family protein	-
C4J97_RS17235	3867810..3868439	-	630	WP_124424250.1	pyroglutamyl-peptidase I	-
C4J97_RS17240	3868447..3869397	-	951	WP_124424251.1	DUF979 domain-containing protein	-
C4J97_RS17245	3869394..3870107	-	714	WP_124424252.1	DUF969 domain-containing protein	-
C4J97_RS17250	3870724..3871011	+	288	WP_124424253.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
C4J97_RS17255	3871001..3871324	+	324	WP_124425635.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
C4J97_RS17260	3871545..3871762	+	218	Protein_3314	tyrosine-type recombinase/integrase	-
C4J97_RS17265	3872239..3874179	-	1941	WP_124424254.1	methyl-accepting chemotaxis protein	-
C4J97_RS17270	3874980..3875747	-	768	WP_124424255.1	DNA adenine methylase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	3843680..3935334	91654

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (7-85)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (10-71)

Sequences

Toxin

Protein

• Length: 108 a.a.
• Molecular weight: 12345.39 Da
• Isoelectric Point: 10.3333

>T100005 WP_124425635.1 NZ_CP027724:3871001-3871324 [Pseudomonas orientalis]
IANEYTVQWDPKALKELRKLDGTIRLQFLKKLQERQTGPRVPSDALHGMKDCYKIKLRSAGYRMVYRVEDERIVILVLAV
GKRERSSVYEQAGKRQAGPLQCKNGEL

Nucleotide

• Length: 324 bp

>T100005 NZ_CP027724:3871001-3871324 [Pseudomonas orientalis]
ATAGCCAATGAGTACACCGTCCAGTGGGATCCAAAAGCACTGAAAGAATTGCGAAAACTCGATGGCACTATCCGCCTGCA
GTTTTTGAAAAAGCTGCAGGAGCGCCAGACCGGACCGCGTGTGCCAAGTGACGCGCTTCACGGTATGAAGGATTGCTACA
AAATCAAATTGCGCAGCGCCGGCTACCGAATGGTGTACCGAGTTGAAGATGAGCGAATTGTCATCCTCGTGTTGGCTGTC
GGTAAACGTGAGCGCAGCTCCGTGTACGAGCAGGCGGGGAAGCGACAGGCTGGGCCATTACAGTGTAAAAATGGCGAATT
GTGA

Antitoxin

Protein

• Length: 96 a.a.
• Molecular weight: 10150.55 Da
• Isoelectric Point: 4.0606

>AT100005 WP_124424253.1 NZ_CP027724:3870724-3871011 [Pseudomonas orientalis]
VQNILADVAVSVSELKKNPSSVLSGANGLPVAVLNHNRVVGYMVPANVYEAMVERLDELELVQLVKARLEANETPVQIAL
DDLIGEAEADIANSQ

Nucleotide

• Length: 288 bp

>AT100005 NZ_CP027724:3870724-3871011 [Pseudomonas orientalis]
GTGCAAAATATTCTGGCTGACGTGGCCGTCAGCGTATCTGAACTGAAGAAGAACCCCTCCTCAGTATTGAGTGGCGCCAA
TGGCTTGCCCGTGGCCGTGTTAAACCACAACCGCGTCGTGGGCTACATGGTCCCTGCCAACGTCTATGAAGCAATGGTCG
AACGCCTGGACGAGCTGGAGCTGGTCCAACTGGTCAAGGCTCGTCTCGAAGCCAACGAAACACCCGTTCAAATAGCGCTC
GACGATCTTATTGGCGAGGCGGAGGCGGATATCGCCAATAGCCAATGA