MGE detailed information

MGE type: Non-Mobilizable plasmid        MGE length: 202753 bp
Accession: NZ_OU015947        Location: 1..202753         Organism: Enterococcus faecium isolate USZ_VRE5_P5       Replicon: plasmid pl1


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KKQ94_RS13950 1..1041 + 1041 WP_002326172.1 replication initiator protein A -
KKQ94_RS13955 1865..2197 + 333 WP_002323647.1 type IV conjugative transfer system protein TraE -
KKQ94_RS13960 2816..3157 + 342 WP_002295674.1 DUF5406 family protein -
KKQ94_RS13965 3394..4644 - 1251 WP_002297404.1 IS110 family transposase ISSpn10 Transposase
KKQ94_RS13970 5054..5293 + 240 WP_002295673.1 hypothetical protein -
KKQ94_RS13975 5360..5569 + 210 WP_002295672.1 hypothetical protein -
KKQ94_RS13980 5629..6300 + 672 WP_002336710.1 class A sortase -
KKQ94_RS13985 6353..8329 + 1977 WP_010729784.1 SpaA isopeptide-forming pilin-related protein -
KKQ94_RS13990 8342..9097 + 756 WP_010729785.1 hypothetical protein VF
KKQ94_RS13995 9094..9918 + 825 WP_002350398.1 pilin N-terminal domain-containing protein -
KKQ94_RS14000 10219..12318 + 2100 WP_010729786.1 isopeptide-forming domain-containing fimbrial protein -
KKQ94_RS14005 12356..14413 - 2058 WP_002350400.1 hypothetical protein VF
KKQ94_RS14010 14527..14739 - 213 WP_002296354.1 hypothetical protein -
KKQ94_RS14015 14926..15393 + 468 WP_002296355.1 hypothetical protein -
KKQ94_RS14020 15390..15632 + 243 WP_002321279.1 DUF5415 family protein -
KKQ94_RS14025 15650..15952 + 303 WP_002296358.1 hypothetical protein -
KKQ94_RS14030 16024..18078 + 2055 WP_059355965.1 hypothetical protein -
KKQ94_RS14035 18078..20690 + 2613 WP_059355955.1 type IV secretory system conjugative DNA transfer family protein -
KKQ94_RS14040 20687..23218 + 2532 WP_002321282.1 hypothetical protein -
KKQ94_RS14045 23270..23602 + 333 WP_002326876.1 hypothetical protein -
KKQ94_RS14050 23603..24196 + 594 WP_002313112.1 hypothetical protein -
KKQ94_RS14055 24359..26005 + 1647 Protein_21 ATPase -
KKQ94_RS14060 26741..28618 + 1878 WP_002305177.1 group II intron reverse transcriptase/maturase -
KKQ94_RS14065 28749..29126 + 378 Protein_23 ATPase -
KKQ94_RS14070 29126..30331 + 1206 WP_002296365.1 glucosaminidase domain-containing protein -
KKQ94_RS14075 30347..30991 + 645 WP_002296371.1 hypothetical protein -
KKQ94_RS14080 31002..31808 + 807 WP_060809402.1 hypothetical protein -
KKQ94_RS14085 31830..32060 + 231 WP_002313120.1 hypothetical protein -
KKQ94_RS14090 32606..32881 + 276 WP_002325546.1 hypothetical protein -
KKQ94_RS14095 32923..33345 + 423 WP_002330592.1 hypothetical protein -
KKQ94_RS14100 33364..34956 + 1593 WP_002330591.1 hypothetical protein Relaxase
KKQ94_RS14105 34968..35303 + 336 WP_002330590.1 hypothetical protein -
KKQ94_RS14110 35418..36377 - 960 WP_002301399.1 IS30 family transposase IS1062 Transposase
KKQ94_RS14115 36521..36715 + 195 WP_002330589.1 hypothetical protein -
KKQ94_RS14120 36747..39119 + 2373 WP_059355962.1 ArdC-like ssDNA-binding domain-containing protein -
KKQ94_RS14125 39180..40640 + 1461 WP_010729792.1 toprim domain-containing protein -
KKQ94_RS14130 40651..42855 + 2205 WP_059355967.1 type IA DNA topoisomerase -
KKQ94_RS14135 42871..43020 + 150 WP_002295632.1 hypothetical protein -
KKQ94_RS14140 43094..43687 + 594 WP_002330563.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein -
KKQ94_RS14145 43703..44602 + 900 WP_002322787.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
KKQ94_RS14150 44605..45090 + 486 WP_002296241.1 single-stranded DNA-binding protein -
KKQ94_RS14155 45456..45716 + 261 WP_002296240.1 hypothetical protein -
KKQ94_RS14160 46157..46363 + 207 WP_002296239.1 hypothetical protein -
KKQ94_RS14165 46363..46614 + 252 WP_002296238.1 hypothetical protein -
KKQ94_RS14170 46629..47066 + 438 WP_002296237.1 hypothetical protein -
KKQ94_RS14175 47059..47766 + 708 WP_002353391.1 hypothetical protein -
KKQ94_RS15635 47931..48131 + 201 WP_002330566.1 hypothetical protein -
KKQ94_RS14180 48147..48326 + 180 WP_002305761.1 hypothetical protein -
KKQ94_RS14185 48667..48930 + 264 WP_002287514.1 hypothetical protein Antitoxin Detail
KKQ94_RS14190 48924..49274 + 351 WP_213313539.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin Detail
KKQ94_RS14195 49298..49912 - 615 WP_010729795.1 Tn3 family transposase TnpR_TnAs2 Transposase
KKQ94_RS14200 50226..50648 + 423 WP_002288787.1 hypothetical protein -
KKQ94_RS14205 50658..50861 + 204 WP_002299573.1 hypothetical protein -
KKQ94_RS14210 51072..51656 + 585 WP_002299575.1 Tn3 family transposase TnBth3 Transposase
KKQ94_RS14215 51845..52525 - 681 WP_010861579.1 IS6 family transposase IS1216E Transposase
KKQ94_RS14220 52601..53244 - 644 Protein_55 transposase -
KKQ94_RS14225 53519..54061 + 543 WP_002298088.1 hypothetical protein -
KKQ94_RS14230 54217..54666 + 450 WP_010729386.1 TlpA disulfide reductase family protein -
KKQ94_RS14240 55934..56089 + 156 Protein_59 4Fe-4S binding protein -
KKQ94_RS14245 56108..57385 + 1278 WP_002301194.1 ABC transporter permease -
KKQ94_RS14250 57395..58051 + 657 WP_002298083.1 putative ABC transporter ATP-binding protein VF
KKQ94_RS14255 58051..59427 + 1377 WP_002301195.1 ABC transporter permease -
KKQ94_RS14260 59557..60756 + 1200 WP_010729384.1 IS256 family transposase ISBsu2 Transposase
KKQ94_RS14265 60728..62224 + 1497 WP_077974472.1 IS1182 family transposase ISEfa7 Transposase
KKQ94_RS15640 62701..62850 + 150 WP_002299930.1 hypothetical protein -
KKQ94_RS14270 62896..63429 + 534 WP_002389935.1 hypothetical protein -
KKQ94_RS14275 63573..64862 + 1290 WP_002299928.1 ABC transporter substrate-binding protein -
KKQ94_RS14280 64947..65819 + 873 WP_002299927.1 sugar ABC transporter permease -
KKQ94_RS14285 65809..66624 + 816 WP_002299926.1 carbohydrate ABC transporter permease -
KKQ94_RS14290 66640..67764 + 1125 WP_002299925.1 Oligosaccharides import ATP-binding protein MsmX VF
KKQ94_RS14295 67742..68545 + 804 WP_002299923.1 metallophosphoesterase -
KKQ94_RS14300 69005..69268 + 264 WP_002389939.1 type II toxin-antitoxin system RelB/DinJ family antitoxin -
KKQ94_RS14305 69252..69587 + 336 WP_014748798.1 type II toxin-antitoxin system PemK/MazF family toxin -
KKQ94_RS14310 69766..70980 - 1215 Protein_74 ISL3 family transposase ISEfa11 Transposase
KKQ94_RS14315 71181..72455 + 1275 WP_010729381.1 ISL3 family transposase IS1476 Transposase
KKQ94_RS14320 72838..73566 - 729 WP_002302980.1 helix-turn-helix domain-containing protein -
KKQ94_RS14325 73544..75118 - 1575 WP_002340467.1 histidine kinase -
KKQ94_RS14330 75347..76285 + 939 WP_002304874.1 sugar ABC transporter permease -
KKQ94_RS14335 76297..77208 + 912 WP_002289655.1 carbohydrate ABC transporter permease -
KKQ94_RS14340 77232..78704 + 1473 WP_010729380.1 extracellular solute-binding protein -
KKQ94_RS14345 78755..79366 + 612 WP_002304878.1 DUF624 domain-containing protein -
KKQ94_RS14350 79396..81309 + 1914 WP_002304880.1 beta-N-acetylhexosaminidase -
KKQ94_RS14355 81437..84418 + 2982 WP_002305865.1 glycoside hydrolase family 2 TIM barrel-domain containing protein -
KKQ94_RS14360 84415..86076 + 1662 WP_002288608.1 hypothetical protein VF
KKQ94_RS14365 86116..87048 + 933 WP_002288609.1 hypothetical protein -
KKQ94_RS14370 87440..88987 - 1548 WP_002296127.1 IS66 family transposase ISRob1 Transposase
KKQ94_RS14375 89089..89442 - 354 WP_002287659.1 IS66 family transposase ISDeal1 Transposase
KKQ94_RS14380 89432..89626 - 195 WP_002285758.1 hypothetical protein -
KKQ94_RS14385 89852..91054 - 1203 WP_010729379.1 site-specific integrase -
KKQ94_RS14390 91057..91251 - 195 WP_002351139.1 DUF3173 domain-containing protein -
KKQ94_RS14395 91298..92146 - 849 WP_010729378.1 rep protein -
KKQ94_RS14400 92351..92701 - 351 WP_010729377.1 hypothetical protein -
KKQ94_RS15645 92879..93742 + 864 WP_010729376.1 helix-turn-helix transcriptional regulator -
KKQ94_RS14410 94366..95358 + 993 WP_005233042.1 ABC transporter permease subunit -
KKQ94_RS14415 95374..96258 + 885 WP_005230433.1 carbohydrate ABC transporter permease -
KKQ94_RS14420 96307..97914 + 1608 WP_010729375.1 ABC transporter substrate-binding protein -
KKQ94_RS14425 97915..99399 + 1485 WP_010729374.1 glycoside hydrolase family 32 protein -
KKQ94_RS14430 99576..100568 + 993 WP_010729373.1 LacI family DNA-binding transcriptional regulator -
KKQ94_RS14435 100620..101489 + 870 WP_010729372.1 ROK family protein -
KKQ94_RS14440 101909..103522 - 1614 WP_002288610.1 glutamine-hydrolyzing GMP synthase -
KKQ94_RS14445 103529..104803 - 1275 WP_060855706.1 ISL3 family transposase IS1476 Transposase
KKQ94_RS14450 105091..105744 + 654 WP_002285815.1 Transcriptional regulatory protein QseB VF
KKQ94_RS14455 105741..107060 + 1320 WP_002300494.1 HAMP domain-containing sensor histidine kinase -
KKQ94_RS14460 107162..107842 - 681 WP_002325565.1 IS6 family transposase IS1216E Transposase
KKQ94_RS14465 107973..108425 + 453 WP_000751236.1 hypothetical protein -
KKQ94_RS14470 108439..109128 + 690 WP_000718009.1 hypothetical protein -
KKQ94_RS14475 109253..111604 + 2352 WP_000344083.1 DUF1906 domain-containing protein -
KKQ94_RS14480 111693..112079 + 387 WP_000391061.1 hypothetical protein -
KKQ94_RS14485 112404..113021 + 618 WP_001224538.1 Tn3 family transposase TnpR_TnAs2 Transposase
KKQ94_RS14490 113062..113361 + 300 WP_000366408.1 BRCT domain-containing protein -
KKQ94_RS14495 113395..113562 + 168 WP_000824191.1 hypothetical protein -
KKQ94_RS14500 113607..114212 - 606 WP_002321606.1 Tn3 family transposase TnpR_ISPa40 Transposase
KKQ94_RS15720 114337..114459 + 123 WP_010729369.1 hypothetical protein -
KKQ94_RS14505 114472..115152 - 681 WP_002319817.1 IS6 family transposase IS1297 Transposase
KKQ94_RS14510 115152..115325 - 174 WP_010729368.1 hypothetical protein -
KKQ94_RS14515 115620..116171 - 552 WP_002303113.1 DUF334 domain-containing protein -
KKQ94_RS14520 116266..116646 - 381 Protein_117 IS6 family transposase IS1216V Transposase
KKQ94_RS14525 116716..117396 + 681 WP_002319817.1 IS6 family transposase IS1297 Transposase
KKQ94_RS14530 117740..117994 + 255 Protein_119 replication initiation protein -
KKQ94_RS14535 118064..118576 + 513 WP_002387940.1 IS3 family transposase ISPa31 Transposase
KKQ94_RS14540 118573..119610 + 1038 WP_002303110.1 IS3 family transposase ISSde10 Transposase
KKQ94_RS14545 119770..119946 + 177 Protein_122 IS6 family transposase -
KKQ94_RS14550 120001..121311 + 1311 Protein_123 Bifunctional AAC/APH ARG
KKQ94_RS14555 121510..122190 + 681 WP_001015311.1 IS6 family transposase IS1216E Transposase
KKQ94_RS14560 122530..123699 - 1170 WP_002300493.1 IS256 family transposase ISEfa13 Transposase
KKQ94_RS14565 123937..124221 + 285 WP_074398953.1 Gfo/Idh/MocA family oxidoreductase -
KKQ94_RS14570 124259..124939 + 681 WP_001015311.1 IS6 family transposase IS1216E Transposase
KKQ94_RS14575 124921..125703 + 783 WP_255310292.1 PTS transporter subunit IIC -
KKQ94_RS14580 125737..126021 + 285 WP_002300838.1 PTS sugar transporter subunit IIB -
KKQ94_RS14585 126023..126538 + 516 WP_002300840.1 YjbQ family protein -
KKQ94_RS14590 126554..127216 + 663 WP_002300841.1 Ribulose-phosphate 3-epimerase VF
KKQ94_RS14595 127223..127795 + 573 WP_002300842.1 3-hexulose-6-phosphate isomerase VF
KKQ94_RS14600 127982..129502 - 1521 WP_002300843.1 IS66 family transposase ISDeal1 Transposase
KKQ94_RS14605 129745..129930 - 186 WP_002305884.1 IS66 family transposase ISEbi1 Transposase
KKQ94_RS14610 129914..130096 - 183 WP_002300846.1 hypothetical protein -
KKQ94_RS14615 130337..130555 + 219 Protein_136 IS256 family transposase ISLgar5 Transposase
KKQ94_RS14620 131050..131649 + 600 WP_002301839.1 Tyrosine recombinase XerC VF
KKQ94_RS14625 131713..132312 + 600 WP_002322465.1 AbiH family protein -
KKQ94_RS14630 132342..132993 - 652 Protein_139 IS6 family transposase IS1216V Transposase
KKQ94_RS14635 133328..134200 - 873 WP_002292418.1 ROK family protein -
KKQ94_RS14640 134464..136410 - 1947 WP_002293868.1 sucrose-specific PTS transporter subunit IIBC -
KKQ94_RS14645 136595..138034 + 1440 WP_002302078.1 sucrose-6-phosphate hydrolase -
KKQ94_RS14650 138036..138998 + 963 WP_002302077.1 LacI family DNA-binding transcriptional regulator -
KKQ94_RS14655 139219..140514 - 1296 WP_002297218.1 ISL3 family transposase ISEfa11 Transposase
KKQ94_RS14660 140690..142116 - 1427 Protein_145 IS3 family transposase ISEfa10 Transposase
KKQ94_RS14665 142359..142814 + 456 WP_002301718.1 IS200-IS605 family transposase ISAac3 Transposase
KKQ94_RS14670 143079..143177 + 99 Protein_147 IS30 family transposase -
KKQ94_RS15650 143400..143630 - 231 WP_002289255.1 resolvase -
KKQ94_RS14675 143860..144678 - 819 WP_002289254.1 MurR/RpiR family transcriptional regulator -
KKQ94_RS14680 144839..145528 + 690 WP_002289253.1 N-acetylmannosamine-6-phosphate 2-epimerase -
KKQ94_RS14685 145542..147044 + 1503 WP_002289252.1 PTS transporter subunit EIIC -
KKQ94_RS14690 147057..147533 + 477 WP_002300328.1 PTS glucose transporter subunit IIA -
KKQ94_RS14695 147630..147740 - 111 Protein_153 transposase -
KKQ94_RS14705 150311..150829 + 519 WP_002287870.1 ClbS/DfsB family four-helix bundle protein -
KKQ94_RS14710 151966..152373 - 408 WP_002329899.1 type II toxin-antitoxin system death-on-curing family toxin -
KKQ94_RS14715 152370..152603 - 234 WP_002290351.1 addiction module antitoxin -
KKQ94_RS14720 152937..154022 + 1086 WP_002290352.1 tyrosine recombinase XerS -
KKQ94_RS14725 154306..154971 - 666 WP_002324528.1 site-specific integrase -
KKQ94_RS14730 155125..155274 - 150 WP_002290356.1 hypothetical protein -
KKQ94_RS14735 155267..155476 - 210 WP_002290357.1 DUF3173 domain-containing protein -
KKQ94_RS14740 155798..156904 - 1107 Protein_162 IS4 family transposase IS641 Transposase
KKQ94_RS14745 156981..158441 - 1461 WP_002335326.1 sucrose phosphorylase -
KKQ94_RS14750 158438..159658 - 1221 WP_002342361.1 alpha-amylase family glycosyl hydrolase -
KKQ94_RS14755 159719..161902 - 2184 WP_002290367.1 alpha-galactosidase -
KKQ94_RS14760 161942..162772 - 831 WP_002290368.1 carbohydrate ABC transporter permease -
KKQ94_RS14765 162784..163656 - 873 WP_002290370.1 sugar ABC transporter permease -
KKQ94_RS14770 163666..164925 - 1260 WP_002290371.1 extracellular solute-binding protein -
KKQ94_RS14775 165073..166383 - 1311 WP_002329911.1 alpha-glucosidase/alpha-galactosidase -
KKQ94_RS14780 166415..167239 - 825 WP_002350071.1 carbohydrate ABC transporter permease -
KKQ94_RS14785 167255..168151 - 897 Protein_171 sugar ABC transporter permease -
KKQ94_RS14790 168234..169346 - 1113 Protein_172 sugar ABC transporter substrate-binding protein -
KKQ94_RS15725 169374..169499 - 126 WP_002290377.1 hypothetical protein -
KKQ94_RS14795 169637..170662 - 1026 WP_002338088.1 LacI family DNA-binding transcriptional regulator -
KKQ94_RS14800 170907..172178 - 1272 WP_002290379.1 substrate-binding domain-containing protein -
KKQ94_RS15655 172462..172833 - 372 WP_002290380.1 VOC family protein -
KKQ94_RS15660 172873..173409 - 537 WP_002342357.1 VOC family protein -
KKQ94_RS14810 173457..173894 + 438 WP_229033435.1 IS91 family transposase ISCARN110 Transposase
KKQ94_RS14815 174067..174621 - 555 WP_002290383.1 tyrosine-type recombinase/integrase -
KKQ94_RS14820 175094..176263 - 1170 WP_002300314.1 IS256 family transposase ISEfa13 Transposase
KKQ94_RS14825 177283..177822 - 540 WP_010728942.1 hypothetical protein -
KKQ94_RS14830 177962..178642 - 681 Protein_182 IS6 family transposase IS1297 Transposase
KKQ94_RS14835 178964..179185 - 222 WP_002311006.1 hypothetical protein -
KKQ94_RS14840 179283..179585 - 303 WP_002350363.1 hypothetical protein -
KKQ94_RS14845 179768..180382 + 615 Protein_185 Tn3 family transposase TnBth3 Transposase
KKQ94_RS14850 180752..181753 - 1002 WP_002344895.1 DUF4062 domain-containing protein -
KKQ94_RS14855 181912..182178 - 267 WP_002344896.1 helix-turn-helix transcriptional regulator -
KKQ94_RS14860 182168..182524 - 357 WP_002344897.1 type II toxin-antitoxin system RelE/ParE family toxin -
KKQ94_RS14865 182659..183339 + 681 WP_016252778.1 IS6 family transposase IS1216E Transposase
KKQ94_RS14870 183551..183736 - 186 Protein_190 type I restriction endonuclease subunit S -
KKQ94_RS14875 183792..184472 - 681 WP_044383156.1 IS6 family transposase IS1297 Transposase
KKQ94_RS15665 184681..184842 - 162 WP_002349958.1 hypothetical protein -
KKQ94_RS14885 185102..185650 - 549 WP_002292681.1 hypothetical protein -
KKQ94_RS14890 185651..186508 - 858 WP_002292680.1 ParA family protein -
KKQ94_RS14895 186792..187078 - 287 Protein_195 type II toxin-antitoxin system RelE/ParE family toxin -
KKQ94_RS14900 187068..187397 - 330 WP_002292678.1 AbrB family transcriptional regulator -
KKQ94_RS14905 187474..187746 - 273 WP_002314366.1 Txe/YoeB family addiction module toxin Toxin Detail
KKQ94_RS14910 187746..188009 - 264 WP_002297422.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin Detail
KKQ94_RS14915 188243..189151 + 909 Protein_199 IS982 family transposase ISEfm1 Transposase
KKQ94_RS14920 189154..190329 - 1176 WP_002336205.1 MFS transporter -
KKQ94_RS14925 190332..192581 - 2250 WP_002314387.1 alpha-galactosidase -
KKQ94_RS14930 192678..193469 - 792 Protein_202 AraC family transcriptional regulator -
KKQ94_RS14935 193631..194779 - 1149 WP_002287525.1 IS200-IS605 family transposase ISEfa4 Transposase
KKQ94_RS14940 194796..195200 - 405 WP_002287522.1 IS200-IS605 family transposase ISEfa4 Transposase
KKQ94_RS14945 195505..196413 - 909 Protein_205 IS982 family transposase ISEfm1 Transposase
KKQ94_RS14950 196507..197442 - 936 WP_002323400.1 hypothetical protein -
KKQ94_RS14955 198001..198318 - 318 WP_002290394.1 type II toxin-antitoxin system RelE/ParE family toxin -
KKQ94_RS14960 198319..198573 - 255 WP_002323399.1 hypothetical protein -
KKQ94_RS14965 198932..199336 + 405 WP_002287522.1 IS200-IS605 family transposase ISEfa4 Transposase
KKQ94_RS14970 199353..200501 + 1149 WP_002287525.1 IS200-IS605 family transposase ISEfa4 Transposase
KKQ94_RS15670 200724..200864 - 141 WP_002290398.1 hypothetical protein -
KKQ94_RS14985 201502..201588 - 87 Protein_212 single-stranded DNA-binding protein -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance