MGE detailed information
MGE type: Integrative_Conjugative_Elements MGE length: 150324 bp
Accession: NZ_LR135226 Location: 197977..348300 Organism: Enterococcus faecium isolate E7025 Replicon: chromosome
Accession: NZ_LR135226 Location: 197977..348300 Organism: Enterococcus faecium isolate E7025 Replicon: chromosome
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EQB58_RS01020 () | 193299..193622 | - | 324 | WP_002289744.1 | DUF960 domain-containing protein | - |
| EQB58_RS01025 () | 193947..194552 | - | 606 | WP_002289745.1 | 50S ribosomal protein L25/general stress protein Ctc | - |
| EQB58_RS01030 () | 194882..195598 | + | 717 | WP_002289747.1 | pseudouridine synthase | - |
| EQB58_RS01035 () | 195611..196306 | + | 696 | WP_002289749.1 | YjjG family noncanonical pyrimidine nucleotidase | - |
| EQB58_RS01040 () | 196390..197019 | + | 630 | WP_002289751.1 | uridine kinase | - |
| EQB58_RS01050 () | 197534..198873 | + | 1340 | WP_086953915.1 | IS3 family transposase ISEnfa3 | Transposase |
| EQB58_RS01055 () | 198942..199544 | + | 603 | WP_002294220.1 | TVP38/TMEM64 family protein | - |
| EQB58_RS01060 () | 199566..200054 | + | 489 | WP_002296548.1 | GNAT family N-acetyltransferase | - |
| EQB58_RS01065 () | 200376..201749 | + | 1374 | WP_002296549.1 | hypothetical protein | - |
| EQB58_RS01070 () | 201733..202170 | + | 438 | WP_002296550.1 | YaiI/YqxD family protein | - |
| EQB58_RS01075 () | 202450..204195 | - | 1746 | WP_002296551.1 | AarF/ABC1/UbiB kinase family protein | - |
| EQB58_RS01080 () | 204391..205467 | + | 1077 | WP_002293424.1 | D-alanine--D-alanine ligase | - |
| EQB58_RS01085 () | 205620..206972 | + | 1353 | WP_002304063.1 | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase | - |
| EQB58_RS01090 () | 207294..208805 | + | 1512 | WP_002296553.1 | DEAD/DEAH box helicase | - |
| EQB58_RS01095 () | 208935..209285 | + | 351 | WP_002296554.1 | holo-ACP synthase | - |
| EQB58_RS01100 () | 209301..210422 | + | 1122 | WP_002296555.1 | alanine racemase | - |
| EQB58_RS01105 () | 210433..210795 | + | 363 | WP_002289874.1 | type II toxin-antitoxin system PemK/MazF family toxin | - |
| EQB58_RS01115 () | 210971..211240 | - | 270 | WP_002293413.1 | 30S ribosomal protein S14 | - |
| EQB58_RS01120 () | 211430..212377 | + | 948 | WP_002294206.1 | NADP-dependent oxidoreductase | - |
| EQB58_RS01125 () | 212683..215388 | + | 2706 | WP_002296556.1 | YhgE/Pip domain-containing protein | - |
| EQB58_RS01135 () | 215986..217809 | + | 1824 | WP_002294202.1 | APC family permease | - |
| EQB58_RS01140 () | 217951..218136 | - | 186 | WP_002296558.1 | transcriptional regulator | - |
| EQB58_RS01150 () | 218612..218875 | + | 264 | WP_002296559.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| EQB58_RS01155 () | 218875..219141 | + | 267 | WP_002296560.1 | Txe/YoeB family addiction module toxin | Toxin Detail |
| EQB58_RS01160 () | 219342..219830 | + | 489 | WP_002296561.1 | mannosyl-glycoprotein endo-beta-N-acetylglucosamidase | - |
| EQB58_RS01165 () | 220371..221042 | - | 672 | WP_002302663.1 | ABC transporter permease | - |
| EQB58_RS01170 () | 221039..221956 | - | 918 | WP_002296564.1 | osmoprotectant ABC transporter substrate-binding protein | - |
| EQB58_RS01175 () | 221953..222594 | - | 642 | WP_002293405.1 | ABC transporter permease | - |
| EQB58_RS01180 () | 222598..223765 | - | 1168 | Protein_220 | Carnitine transport ATP-binding protein OpuCA | VF |
| EQB58_RS01185 () | 223958..224989 | + | 1032 | WP_002296565.1 | tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA | - |
| EQB58_RS01190 () | 225608..228247 | + | 2640 | WP_002289743.1 | cation-translocating P-type ATPase | - |
| EQB58_RS01195 () | 228415..229113 | - | 699 | WP_002296566.1 | DUF975 family protein | - |
| EQB58_RS01200 () | 229331..230476 | + | 1146 | WP_002294183.1 | tRNA guanosine(34) transglycosylase Tgt | - |
| EQB58_RS01205 () | 230573..230953 | + | 381 | WP_002294182.1 | preprotein translocase subunit YajC | - |
| EQB58_RS01210 () | 231258..233855 | + | 2598 | WP_002296567.1 | Aldehyde-alcohol dehydrogenase | VF |
| EQB58_RS01215 () | 234084..235190 | + | 1107 | WP_002288261.1 | glycosyl hydrolase | - |
| EQB58_RS01220 () | 235207..236231 | + | 1025 | Protein_228 | TRAP transporter substrate-binding protein | - |
| EQB58_RS01225 () | 236237..236716 | + | 480 | WP_002300788.1 | TRAP transporter small permease | - |
| EQB58_RS01230 () | 236732..237310 | + | 579 | WP_002300787.1 | TRAP transporter large permease subunit | - |
| EQB58_RS01235 () | 237342..238681 | + | 1340 | WP_086953915.1 | IS3 family transposase ISEnfa3 | Transposase |
| EQB58_RS01240 () | 238725..238931 | + | 207 | WP_126145175.1 | TRAP transporter large permease subunit | - |
| EQB58_RS01245 () | 238913..239218 | + | 306 | WP_002300046.1 | 5-dehydro-4-deoxy-D-glucuronate isomerase | - |
| EQB58_RS01250 () | 239238..240041 | + | 804 | WP_033582433.1 | 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase | VF |
| EQB58_RS01255 () | 240290..241354 | - | 1065 | WP_002300048.1 | type 2 isopentenyl-diphosphate Delta-isomerase | - |
| EQB58_RS01260 () | 241351..242436 | - | 1086 | WP_002288233.1 | phosphomevalonate kinase | - |
| EQB58_RS01265 () | 242449..243426 | - | 978 | WP_002300050.1 | diphosphomevalonate decarboxylase | - |
| EQB58_RS01270 () | 243419..244363 | - | 945 | WP_002288231.1 | mevalonate kinase | - |
| EQB58_RS01275 () | 244679..245338 | + | 660 | WP_002352356.1 | deoxynucleoside kinase | - |
| EQB58_RS01280 () | 245423..246328 | + | 906 | WP_002300052.1 | magnesium transporter CorA family protein | - |
| EQB58_RS01285 () | 246330..246962 | - | 633 | WP_002300053.1 | pentapeptide repeat-containing protein | - |
| EQB58_RS01290 () | 247282..247806 | + | 525 | WP_002293357.1 | translation initiation factor IF-3 | - |
| EQB58_RS01295 () | 247878..248078 | + | 201 | WP_002289309.1 | 50S ribosomal protein L35 | - |
| EQB58_RS01300 () | 248131..248490 | + | 360 | WP_002289310.1 | 50S ribosomal protein L20 | - |
| EQB58_RS01305 () | 248926..249267 | + | 342 | WP_002341586.1 | hypothetical protein | - |
| EQB58_RS01310 () | 249374..250561 | - | 1188 | WP_002296840.1 | IS256 family transposase IS16 | Transposase |
| EQB58_RS01315 () | 250658..251554 | + | 897 | WP_080388548.1 | citrate transporter | - |
| EQB58_RS01320 () | 251602..253731 | + | 2130 | WP_002341584.1 | hydantoinase/oxoprolinase | - |
| EQB58_RS01325 () | 253706..254395 | + | 690 | WP_002302159.1 | hypothetical protein | - |
| EQB58_RS01335 () | 254803..255489 | - | 687 | WP_002289316.1 | GntR family transcriptional regulator | - |
| EQB58_RS01340 () | 255625..255819 | - | 195 | WP_002315615.1 | hypothetical protein | - |
| EQB58_RS01345 () | 255869..256309 | - | 441 | WP_002301667.1 | acyl-CoA thioesterase | - |
| EQB58_RS01350 () | 256313..257158 | - | 846 | WP_002299303.1 | NAD(P)H-hydrate dehydratase | - |
| EQB58_RS01355 () | 257307..258725 | + | 1419 | WP_002294157.1 | dipeptidase PepV | - |
| EQB58_RS01360 () | 258823..260118 | - | 1296 | WP_002297218.1 | ISL3 family transposase ISEfa11 | Transposase |
| EQB58_RS01370 () | 260323..261525 | - | 1203 | WP_002299302.1 | hypothetical protein | - |
| EQB58_RS01375 () | 261512..263299 | - | 1788 | WP_002299301.1 | hypothetical protein | - |
| EQB58_RS01380 () | 263312..264265 | - | 954 | WP_002299300.1 | glycosyltransferase family 2 protein | - |
| EQB58_RS01385 () | 264450..264800 | - | 351 | WP_002309710.1 | PepSY domain-containing protein | - |
| EQB58_RS01390 () | 265000..266079 | + | 1080 | WP_002294156.1 | glutamyl aminopeptidase | - |
| EQB58_RS01395 () | 266222..266542 | + | 321 | WP_002292632.1 | thioredoxin family protein | - |
| EQB58_RS01400 () | 266564..267028 | + | 465 | WP_002345012.1 | universal stress protein | - |
| EQB58_RS01410 () | 267224..267829 | + | 606 | WP_002313997.1 | DUF4479 domain-containing tRNA-binding protein | - |
| EQB58_RS01415 () | 267868..269157 | - | 1290 | WP_002290101.1 | Serine protease Do-like HtrA | VF |
| EQB58_RS01420 () | 269585..270064 | + | 480 | WP_002345011.1 | 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH | - |
| EQB58_RS01430 () | 270417..270731 | + | 315 | WP_000420682.1 | YdcP family protein | - |
| EQB58_RS01435 () | 270747..271133 | + | 387 | WP_000985015.1 | YdcP family protein | - |
| EQB58_RS01440 () | 271162..272547 | + | 1386 | WP_000813488.1 | DNA translocase FtsK | - |
| EQB58_RS01445 () | 272550..272703 | + | 154 | Protein_269 | conjugal transfer protein | - |
| EQB58_RS01450 () | 272726..273931 | + | 1206 | WP_000398284.1 | replication initiation factor domain-containing protein | - |
| EQB58_RS01455 () | 274715..276625 | + | 1911 | WP_002286940.1 | group II intron reverse transcriptase/maturase | - |
| EQB58_RS01460 () | 276729..276953 | + | 225 | WP_032509114.1 | hypothetical protein | - |
| EQB58_RS01465 () | 277070..277567 | + | 498 | WP_002345010.1 | antirestriction protein ArdA | - |
| EQB58_RS01470 () | 277654..278046 | + | 393 | WP_002345009.1 | conjugal transfer protein | - |
| EQB58_RS01475 () | 278030..280477 | + | 2448 | WP_000331148.1 | ATP-binding protein | - |
| EQB58_RS01480 () | 280480..282663 | + | 2184 | WP_002345008.1 | membrane protein | - |
| EQB58_RS01485 () | 282660..283661 | + | 1002 | WP_002345007.1 | hypothetical protein | VF |
| EQB58_RS01490 () | 283676..284590 | + | 915 | WP_002345006.1 | conjugal transfer protein | - |
| EQB58_RS01495 () | 284835..284951 | + | 117 | WP_001814923.1 | tetracycline resistance determinant leader peptide | - |
| EQB58_RS01500 () | 284967..286886 | + | 1920 | WP_002345005.1 | tetracycline resistance ribosomal protection protein Tet(M) | VF |
| EQB58_RS01505 () | 286984..288357 | + | 1374 | WP_002345004.1 | tetracycline efflux MFS transporter Tet(L) | ARG |
| EQB58_RS01515 () | 288921..290183 | + | 1263 | WP_000119405.1 | plasmid recombination protein | - |
| EQB58_RS01520 () | 290428..291315 | + | 888 | WP_025479406.1 | protein rep | - |
| EQB58_RS01525 () | 291338..292018 | - | 681 | WP_001015311.1 | IS6 family transposase IS1216E | Transposase |
| EQB58_RS01530 () | 292770..292916 | - | 147 | Protein_285 | 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B) | - |
| EQB58_RS01535 () | 292971..293651 | - | 681 | WP_001015311.1 | IS6 family transposase IS1216E | Transposase |
| EQB58_RS01540 () | 293922..295964 | + | 2043 | WP_002336644.1 | PTS sugar transporter subunit IIA | - |
| EQB58_RS01545 () | 295975..296595 | + | 621 | WP_002336645.1 | bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase | - |
| EQB58_RS01550 () | 296607..297065 | + | 459 | WP_002336646.1 | PTS sugar transporter subunit IIA | - |
| EQB58_RS01555 () | 297084..297362 | + | 279 | WP_002331203.1 | PTS sugar transporter subunit IIB | - |
| EQB58_RS01560 () | 297387..298754 | + | 1368 | WP_002336647.1 | PTS galactitol transporter subunit IIC | - |
| EQB58_RS01565 () | 298769..299914 | + | 1146 | WP_002331205.1 | galactonate dehydratase | - |
| EQB58_RS01570 () | 299941..300432 | + | 492 | WP_002331206.1 | hypothetical protein | - |
| EQB58_RS01575 () | 300875..302074 | + | 1200 | WP_002345001.1 | MFS transporter | - |
| EQB58_RS01580 () | 302569..303327 | - | 759 | WP_002331208.1 | MurR/RpiR family transcriptional regulator | - |
| EQB58_RS01585 () | 303495..304430 | + | 936 | WP_002331209.1 | 1-phosphofructokinase | - |
| EQB58_RS01590 () | 304427..305872 | + | 1446 | WP_002336649.1 | PTS fructose transporter subunit IIBC | - |
| EQB58_RS01595 () | 305900..306355 | + | 456 | WP_002336650.1 | fructose PTS transporter subunit IIA | - |
| EQB58_RS01600 () | 306374..307348 | + | 975 | WP_002336651.1 | tagatose-bisphosphate aldolase | - |
| EQB58_RS01605 () | 307459..308020 | - | 562 | Protein_300 | TetR/AcrR family transcriptional regulator | - |
| EQB58_RS01610 () | 308164..308778 | + | 615 | WP_002336652.1 | GNAT family N-acetyltransferase | - |
| EQB58_RS01615 () | 309019..309402 | + | 384 | WP_002331215.1 | GntR family transcriptional regulator | - |
| EQB58_RS01625 () | 309765..310274 | + | 510 | WP_002301781.1 | DUF1456 family protein | - |
| EQB58_RS01630 () | 310374..311024 | + | 651 | WP_002298023.1 | hypothetical protein | - |
| EQB58_RS01635 () | 311475..312413 | + | 939 | WP_002291914.1 | 2-dehydropantoate 2-reductase | - |
| EQB58_RS01640 () | 312426..313478 | + | 1053 | WP_002291912.1 | PTS sugar transporter subunit IIC | - |
| EQB58_RS01645 () | 313536..313982 | + | 447 | Protein_307 | DUF998 domain-containing protein | - |
| EQB58_RS01650 () | 314034..314312 | - | 279 | Protein_308 | IS6 family transposase | - |
| EQB58_RS01665 () | 315935..316033 | + | 99 | Protein_310 | IS30 family transposase | - |
| EQB58_RS01670 () | 316256..316486 | - | 231 | WP_002289255.1 | resolvase | - |
| EQB58_RS01675 () | 316716..317534 | - | 819 | WP_002289254.1 | MurR/RpiR family transcriptional regulator | - |
| EQB58_RS01680 () | 317695..318384 | + | 690 | WP_002289253.1 | N-acetylmannosamine-6-phosphate 2-epimerase | - |
| EQB58_RS01685 () | 318398..319900 | + | 1503 | WP_002289252.1 | PTS transporter subunit EIIC | - |
| EQB58_RS01690 () | 319913..320389 | + | 477 | WP_002300328.1 | PTS glucose transporter subunit IIA | - |
| EQB58_RS01695 () | 320548..321507 | - | 960 | WP_002293280.1 | IS30 family transposase IS6770 | Transposase |
| EQB58_RS01700 () | 321744..322922 | + | 1179 | WP_000997695.1 | IS256 family transposase ISEf1 | Transposase |
| EQB58_RS01705 () | 323001..323336 | - | 336 | WP_002300909.1 | PRD domain-containing protein | - |
| EQB58_RS01710 () | 323622..325502 | + | 1881 | WP_002300907.1 | heavy metal translocating P-type ATPase | - |
| EQB58_RS01715 () | 325581..325808 | + | 228 | WP_002300905.1 | cation transporter | - |
| EQB58_RS01720 () | 325813..326355 | + | 543 | WP_002300904.1 | DNA-binding protein | - |
| EQB58_RS01725 () | 326606..327283 | + | 678 | WP_025477866.1 | DUF4767 domain-containing protein | - |
| EQB58_RS01730 () | 327604..328845 | + | 1242 | WP_002300900.1 | serine/threonine transporter SstT | - |
| EQB58_RS01735 () | 328992..329627 | + | 636 | WP_002294730.1 | DUF998 domain-containing protein | - |
| EQB58_RS01740 () | 329818..330561 | + | 744 | WP_002300898.1 | tRNA pseudouridine(38-40) synthase TruA | - |
| EQB58_RS01745 () | 330795..331628 | + | 834 | WP_002300896.1 | Peptide methionine sulfoxide reductase MsrA | VF |
| EQB58_RS01750 () | 331742..332702 | + | 961 | Protein_327 | aldo/keto reductase | - |
| EQB58_RS01755 () | 332991..333689 | + | 699 | WP_002300890.1 | FadR family transcriptional regulator | - |
| EQB58_RS01760 () | 333839..334294 | + | 456 | Protein_329 | PTS sugar transporter subunit IIC | - |
| EQB58_RS01765 () | 334375..335501 | + | 1127 | WP_127823948.1 | IS3 family transposase ISBce13 | Transposase |
| EQB58_RS01770 () | 335546..336502 | + | 957 | Protein_331 | glycoside hydrolase family 1 protein | - |
| EQB58_RS01775 () | 336768..338063 | - | 1296 | WP_002297185.1 | ISL3 family transposase ISEfa5 | Transposase |
| EQB58_RS01780 () | 338425..338745 | + | 321 | WP_002301150.1 | PTS sugar transporter subunit IIB | - |
| EQB58_RS01785 () | 338771..339088 | + | 318 | WP_002287579.1 | PTS lactose/cellobiose transporter subunit IIA | - |
| EQB58_RS01790 () | 339117..340366 | + | 1250 | Protein_335 | PTS sugar transporter subunit IIC | - |
| EQB58_RS01795 () | 340495..340959 | + | 465 | WP_002299899.1 | GNAT family N-acetyltransferase | - |
| EQB58_RS01800 () | 340988..341308 | - | 321 | WP_002287574.1 | YrhK family protein | - |
| EQB58_RS01805 () | 341339..342472 | - | 1134 | WP_002301143.1 | alcohol dehydrogenase catalytic domain-containing protein | - |
| EQB58_RS01810 () | 342850..343023 | - | 174 | WP_172442912.1 | hypothetical protein | - |
| EQB58_RS16605 () | 343000..343119 | - | 120 | Protein_340 | tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD | - |
| EQB58_RS01815 () | 343123..344817 | - | 1695 | WP_002299871.1 | oleate hydratase | - |
| EQB58_RS01820 () | 344874..345002 | - | 129 | WP_002287569.1 | hypothetical protein | - |
| EQB58_RS01825 () | 345001..345249 | + | 249 | WP_002321251.1 | hypothetical protein | - |
| EQB58_RS01830 () | 345441..345806 | + | 366 | WP_002287567.1 | DUF1622 domain-containing protein | - |
| EQB58_RS01835 () | 345803..346168 | + | 366 | WP_002287564.1 | DUF1622 domain-containing protein | - |
| EQB58_RS01840 () | 346260..347564 | - | 1305 | WP_002344946.1 | hypothetical protein | - |
| EQB58_RS01845 () | 347697..349049 | + | 1353 | Protein_347 | IS3 family transposase | - |
| EQB58_RS01850 () | 349469..350428 | - | 960 | WP_002293280.1 | IS30-like element IS6770 family transposase | - |
| EQB58_RS01855 () | 350655..352490 | + | 1836 | WP_002302155.1 | tyrosine decarboxylase | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|