MGE detailed information
MGE type: Non-Mobilizable plasmid MGE length: 149005 bp
Accession: NZ_LR135175 Location: 1..149005 Organism: Enterococcus faecium isolate E4402 Replicon: plasmid 2
Accession: NZ_LR135175 Location: 1..149005 Organism: Enterococcus faecium isolate E4402 Replicon: plasmid 2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EL348_RS13825 () | 1..1041 | + | 1041 | WP_002323095.1 | replication initiator protein A | - |
| EL348_RS13830 () | 1881..2213 | + | 333 | WP_002322486.1 | hypothetical protein | - |
| EL348_RS14895 () | 2832..2987 | + | 156 | WP_002299035.1 | DUF5406 family protein | - |
| EL348_RS13835 () | 2991..3173 | + | 183 | WP_002317437.1 | DUF5406 family protein | - |
| EL348_RS13840 () | 3340..3579 | + | 240 | WP_002347362.1 | hypothetical protein | - |
| EL348_RS13845 () | 3645..3884 | + | 240 | WP_002322851.1 | hypothetical protein | - |
| EL348_RS14930 () | 4011..4205 | + | 195 | Protein_6 | sortase | - |
| EL348_RS14900 () | 4194..4888 | + | 695 | Protein_7 | EpaQ family protein | - |
| EL348_RS13855 () | 4970..5641 | + | 672 | WP_002347361.1 | class A sortase | - |
| EL348_RS13860 () | 5694..7670 | + | 1977 | WP_002347360.1 | isopeptide-forming domain-containing fimbrial protein | - |
| EL348_RS13865 () | 7685..8437 | + | 753 | WP_002293487.1 | hypothetical protein | VF |
| EL348_RS13870 () | 8453..9214 | + | 762 | WP_002295669.1 | hypothetical protein | - |
| EL348_RS13875 () | 9227..9487 | + | 261 | WP_002293489.1 | hypothetical protein | - |
| EL348_RS13880 () | 9484..11574 | + | 2091 | WP_002326524.1 | isopeptide-forming domain-containing fimbrial protein | - |
| EL348_RS13885 () | 11601..12065 | + | 465 | WP_025477618.1 | hypothetical protein | - |
| EL348_RS13890 () | 12062..12304 | + | 243 | WP_002305229.1 | DUF5415 family protein | - |
| EL348_RS13895 () | 12322..12624 | + | 303 | WP_002295662.1 | hypothetical protein | - |
| EL348_RS13900 () | 12694..14748 | + | 2055 | WP_002323241.1 | hypothetical protein | - |
| EL348_RS13905 () | 14748..17189 | + | 2442 | Protein_18 | type IV secretory system conjugative DNA transfer family protein | - |
| EL348_RS13910 () | 17282..18241 | + | 960 | WP_002305939.1 | IS30 family transposase IS1062 | Transposase |
| EL348_RS14905 () | 18288..18425 | + | 138 | WP_172598299.1 | hypothetical protein | - |
| EL348_RS13915 () | 18422..20818 | + | 2397 | WP_002295657.1 | hypothetical protein | - |
| EL348_RS13920 () | 20870..21202 | + | 333 | WP_002295656.1 | hypothetical protein | - |
| EL348_RS13925 () | 21203..21796 | + | 594 | WP_002305169.1 | hypothetical protein | - |
| EL348_RS13930 () | 21821..22399 | + | 579 | WP_002295653.1 | hypothetical protein | - |
| EL348_RS13935 () | 22569..24593 | + | 2025 | WP_002295651.1 | ATPase | - |
| EL348_RS13940 () | 24593..25798 | + | 1206 | WP_002326165.1 | glucosaminidase domain-containing protein | - |
| EL348_RS13945 () | 25814..26458 | + | 645 | WP_002326164.1 | hypothetical protein | - |
| EL348_RS13950 () | 26469..27275 | + | 807 | WP_002326163.1 | hypothetical protein | - |
| EL348_RS13955 () | 27297..27527 | + | 231 | WP_002313120.1 | hypothetical protein | - |
| EL348_RS13960 () | 28040..28336 | + | 297 | WP_002326162.1 | hypothetical protein | - |
| EL348_RS13965 () | 28338..28760 | + | 423 | WP_002322781.1 | hypothetical protein | - |
| EL348_RS13970 () | 28779..30371 | + | 1593 | WP_033627820.1 | hypothetical protein | Relaxase |
| EL348_RS13975 () | 30383..30718 | + | 336 | WP_002326160.1 | hypothetical protein | - |
| EL348_RS13980 () | 30864..31058 | + | 195 | WP_002302840.1 | hypothetical protein | - |
| EL348_RS13985 () | 31194..32444 | - | 1251 | WP_002287107.1 | IS110 family transposase ISSpn10 | Transposase |
| EL348_RS13990 () | 32854..35226 | + | 2373 | WP_002347293.1 | hypothetical protein | - |
| EL348_RS13995 () | 35287..36747 | + | 1461 | WP_002326158.1 | toprim domain-containing protein | - |
| EL348_RS14000 () | 36758..38962 | + | 2205 | WP_025478649.1 | type IA DNA topoisomerase | - |
| EL348_RS14910 () | 38978..39127 | + | 150 | WP_002295632.1 | hypothetical protein | - |
| EL348_RS14005 () | 39208..39804 | + | 597 | WP_002322762.1 | type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein | - |
| EL348_RS14010 () | 39817..40716 | + | 900 | WP_002322763.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | - |
| EL348_RS14015 () | 40719..41204 | + | 486 | WP_002334021.1 | single-stranded DNA-binding protein | - |
| EL348_RS14020 () | 41226..41483 | + | 258 | WP_002322647.1 | hypothetical protein | - |
| EL348_RS14025 () | 41642..41764 | - | 123 | WP_002295624.1 | putative holin-like toxin | - |
| EL348_RS14030 () | 41918..42178 | + | 261 | WP_002324498.1 | hypothetical protein | - |
| EL348_RS14035 () | 42626..42832 | + | 207 | WP_002324499.1 | hypothetical protein | - |
| EL348_RS14040 () | 42832..43083 | + | 252 | WP_002287517.1 | hypothetical protein | - |
| EL348_RS14045 () | 43099..43536 | + | 438 | WP_002305049.1 | hypothetical protein | - |
| EL348_RS14050 () | 43529..44236 | + | 708 | WP_002322978.1 | hypothetical protein | - |
| EL348_RS14060 () | 44858..45042 | + | 185 | Protein_50 | type II toxin-antitoxin system HicA family toxin | - |
| EL348_RS14065 () | 45076..45507 | + | 432 | WP_002305052.1 | type II toxin-antitoxin system HicB family antitoxin | - |
| EL348_RS14070 () | 45681..46634 | - | 954 | WP_002328317.1 | IS30 family transposase IS1252 | Transposase |
| EL348_RS14075 () | 46937..48211 | + | 1275 | WP_002322783.1 | MFS transporter | - |
| EL348_RS14080 () | 48265..49692 | + | 1428 | WP_002322784.1 | glycoside hydrolase family 32 protein | - |
| EL348_RS14085 () | 49705..50577 | + | 873 | WP_002322785.1 | ROK family protein | - |
| EL348_RS14090 () | 50672..51667 | + | 996 | WP_002305056.1 | LacI family DNA-binding transcriptional regulator | - |
| EL348_RS14100 () | 52289..52636 | + | 348 | Protein_57 | Tn3 family transposase TnpR_ISAzs17 | Transposase |
| EL348_RS14105 () | 52940..53194 | + | 255 | WP_002322771.1 | hypothetical protein | - |
| EL348_RS14110 () | 53253..53930 | - | 678 | WP_080011922.1 | GntR family transcriptional regulator | - |
| EL348_RS14115 () | 54115..55560 | + | 1446 | WP_002323045.1 | glycoside hydrolase family 1 protein | - |
| EL348_RS14120 () | 55563..56864 | + | 1302 | WP_002323046.1 | PTS sugar transporter subunit IIC | - |
| EL348_RS14125 () | 57078..57353 | + | 276 | Protein_62 | hypothetical protein | - |
| EL348_RS14130 () | 57669..58622 | - | 954 | WP_060799464.1 | IS30 family transposase IS1252 | Transposase |
| EL348_RS14135 () | 58744..59007 | + | 264 | WP_002300807.1 | uberolysin/carnocyclin family circular bacteriocin | - |
| EL348_RS14145 () | 59379..60557 | + | 1179 | WP_000997695.1 | IS256 family transposase ISEf1 | Transposase |
| EL348_RS14150 () | 60946..62892 | + | 1947 | WP_002300833.1 | PTS sugar transporter subunit IIA | - |
| EL348_RS14155 () | 62895..63350 | + | 456 | WP_002300835.1 | PTS sugar transporter subunit IIA | - |
| EL348_RS14160 () | 63364..64692 | + | 1329 | WP_002300836.1 | PTS galactitol transporter subunit IIC | - |
| EL348_RS14165 () | 64726..65010 | + | 285 | WP_002300838.1 | PTS sugar transporter subunit IIB | - |
| EL348_RS14170 () | 65012..65527 | + | 516 | WP_002300840.1 | YjbQ family protein | - |
| EL348_RS14175 () | 65543..66205 | + | 663 | WP_002300841.1 | Ribulose-phosphate 3-epimerase | VF |
| EL348_RS14180 () | 66212..66784 | + | 573 | WP_002300842.1 | 3-hexulose-6-phosphate isomerase | VF |
| EL348_RS14185 () | 66971..68491 | - | 1521 | WP_002300843.1 | IS66 family transposase ISDeal1 | Transposase |
| EL348_RS14190 () | 68734..68919 | - | 186 | WP_002305884.1 | IS66 family transposase ISEbi1 | Transposase |
| EL348_RS14195 () | 68903..69085 | - | 183 | WP_002300846.1 | hypothetical protein | - |
| EL348_RS14200 () | 69326..69544 | + | 219 | Protein_76 | IS256 family transposase ISLgar5 | Transposase |
| EL348_RS14205 () | 70039..70638 | + | 600 | WP_002301839.1 | Tyrosine recombinase XerD | VF |
| EL348_RS14210 () | 70702..71301 | + | 600 | WP_002322465.1 | bacteriophage abortive infection AbiH family protein | - |
| EL348_RS14215 () | 71331..71982 | - | 652 | Protein_79 | IS6 family transposase IS1216V | Transposase |
| EL348_RS14220 () | 72317..73189 | - | 873 | WP_002292418.1 | ROK family protein | - |
| EL348_RS14225 () | 73453..75399 | - | 1947 | WP_002293868.1 | sucrose-specific PTS transporter subunit IIBC | - |
| EL348_RS14230 () | 75584..77023 | + | 1440 | WP_002302078.1 | sucrose-6-phosphate hydrolase | - |
| EL348_RS14235 () | 77025..77987 | + | 963 | WP_002302077.1 | LacI family DNA-binding transcriptional regulator | - |
| EL348_RS14245 () | 79674..80969 | - | 1296 | WP_002297218.1 | ISL3 family transposase ISEfa11 | Transposase |
| EL348_RS14250 () | 81348..81803 | + | 456 | WP_002301718.1 | IS200-IS605 family transposase ISAac3 | Transposase |
| EL348_RS14260 () | 82068..82166 | + | 99 | Protein_87 | IS30 family transposase | - |
| EL348_RS14270 () | 82849..83667 | - | 819 | WP_002289254.1 | MurR/RpiR family transcriptional regulator | - |
| EL348_RS14275 () | 83828..84517 | + | 690 | WP_002289253.1 | N-acetylmannosamine-6-phosphate 2-epimerase | - |
| EL348_RS14280 () | 84531..86033 | + | 1503 | WP_002289252.1 | PTS transporter subunit EIIC | - |
| EL348_RS14285 () | 86046..86522 | + | 477 | WP_002300328.1 | PTS glucose transporter subunit IIA | - |
| EL348_RS14305 () | 89300..89818 | + | 519 | WP_002287870.1 | ClbS/DfsB family four-helix bundle protein | - |
| EL348_RS14315 () | 90955..91362 | - | 408 | WP_002297442.1 | type II toxin-antitoxin system death-on-curing family toxin | - |
| EL348_RS14320 () | 91359..91592 | - | 234 | WP_002297441.1 | addiction module antitoxin | - |
| EL348_RS14325 () | 91925..93010 | + | 1086 | WP_002297440.1 | tyrosine recombinase XerS | - |
| EL348_RS14330 () | 93296..94474 | + | 1179 | WP_000997695.1 | IS256 family transposase ISEf1 | Transposase |
| EL348_RS14335 () | 94708..95598 | + | 891 | WP_002297439.1 | hypothetical protein | - |
| EL348_RS14340 () | 96035..96589 | - | 555 | WP_002295761.1 | tyrosine-type recombinase/integrase | - |
| EL348_RS14345 () | 97063..98241 | - | 1179 | WP_000997695.1 | IS256 family transposase ISEf1 | Transposase |
| EL348_RS14350 () | 98678..99238 | + | 561 | WP_002347210.1 | hypothetical protein | - |
| EL348_RS14355 () | 99271..100083 | - | 813 | WP_002322679.1 | AAA family ATPase | - |
| EL348_RS14360 () | 100076..101512 | - | 1437 | WP_002322678.1 | DDE-type integrase/transposase/recombinase | - |
| EL348_RS14365 () | 101484..102077 | - | 594 | WP_002322677.1 | Tn3 family transposase TnBth3 | Transposase |
| EL348_RS14370 () | 102309..102539 | + | 231 | WP_002322676.1 | hypothetical protein | Antitoxin Detail |
| EL348_RS14375 () | 102539..102880 | + | 342 | WP_002322675.1 | type II toxin-antitoxin system PemK/MazF family toxin | Toxin Detail |
| EL348_RS14380 () | 103094..104596 | - | 1503 | WP_002322674.1 | xylulokinase | - |
| EL348_RS14385 () | 104669..105721 | - | 1053 | WP_002323515.1 | sugar ABC transporter substrate-binding protein | - |
| EL348_RS14390 () | 105774..106742 | - | 969 | WP_002322672.1 | ABC transporter permease | - |
| EL348_RS14395 () | 106807..108315 | - | 1509 | WP_002322671.1 | sugar ABC transporter ATP-binding protein | - |
| EL348_RS14400 () | 108365..109975 | - | 1611 | WP_002322670.1 | glycoside hydrolase family 43 protein | - |
| EL348_RS14405 () | 110075..111382 | - | 1308 | WP_002322669.1 | xylose isomerase | - |
| EL348_RS14410 () | 111695..112849 | + | 1155 | WP_002323041.1 | ROK family transcriptional regulator | - |
| EL348_RS14415 () | 113375..113620 | + | 246 | WP_002323040.1 | hypothetical protein | - |
| EL348_RS14420 () | 113617..114114 | - | 498 | WP_002316138.1 | Spermidine/spermine N(1)-acetyltransferase | VF |
| EL348_RS14425 () | 114170..115078 | - | 909 | WP_002295743.1 | IS982 family transposase ISEfm1 | Transposase |
| EL348_RS14435 () | 115839..117026 | + | 1188 | WP_002296840.1 | IS256 family transposase IS16 | Transposase |
| EL348_RS14440 () | 117359..118039 | - | 681 | WP_085803942.1 | IS6 family transposase ISS1W | Transposase |
| EL348_RS14935 () | 118110..118199 | - | 90 | Protein_119 | metal-binding protein | - |
| EL348_RS14445 () | 118346..119200 | - | 855 | WP_002322689.1 | prolipoprotein diacylglyceryl transferase | - |
| EL348_RS14450 () | 119185..119523 | - | 339 | WP_002300938.1 | hypothetical protein | - |
| EL348_RS14455 () | 119751..120455 | - | 705 | WP_002292156.1 | Crp/Fnr family transcriptional regulator | - |
| EL348_RS14460 () | 120600..121172 | - | 573 | WP_002292150.1 | DNA protection during starvation protein | VF |
| EL348_RS14470 () | 121727..122899 | + | 1173 | WP_002323279.1 | IS256 family transposase IS256 | Transposase |
| EL348_RS14475 () | 123053..123583 | - | 531 | Protein_125 | IS982 family transposase ISEfm1 | Transposase |
| EL348_RS14480 () | 123655..124947 | + | 1293 | WP_002298232.1 | ISL3 family transposase IS1251 | Transposase |
| EL348_RS14485 () | 125159..126001 | - | 843 | WP_002289586.1 | PRD domain-containing protein | - |
| EL348_RS14490 () | 126038..127504 | - | 1467 | WP_002289584.1 | glycoside hydrolase family 1 protein | - |
| EL348_RS14495 () | 127560..129404 | - | 1845 | WP_002298230.1 | beta-glucoside-specific PTS transporter subunit IIABC | - |
| EL348_RS14500 () | 130006..130956 | + | 951 | WP_002300609.1 | Transcriptional regulatory protein DagR | VF |
| EL348_RS14505 () | 131001..131634 | - | 634 | Protein_131 | peptidase | - |
| EL348_RS14510 () | 131894..132442 | - | 549 | WP_002292681.1 | hypothetical protein | - |
| EL348_RS14515 () | 132443..133300 | - | 858 | WP_002292680.1 | AAA family ATPase | - |
| EL348_RS14520 () | 133586..133873 | - | 288 | WP_002300557.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| EL348_RS14525 () | 133863..134192 | - | 330 | WP_002292678.1 | AbrB family transcriptional regulator | - |
| EL348_RS14530 () | 134269..134415 | - | 147 | Protein_136 | Txe/YoeB family addiction module toxin | - |
| EL348_RS14535 () | 134467..135147 | - | 681 | Protein_137 | IS6 family transposase IS1216V | Transposase |
| EL348_RS14915 () | 135201..135368 | - | 168 | WP_002322961.1 | hypothetical protein | - |
| EL348_RS14540 () | 135401..136801 | - | 1401 | WP_002298077.1 | YfcC family protein | - |
| EL348_RS14545 () | 136849..137226 | - | 378 | Protein_140 | amidohydrolase family protein | - |
| EL348_RS14550 () | 137336..138523 | + | 1188 | WP_002296840.1 | IS256 family transposase IS16 | Transposase |
| EL348_RS14555 () | 138581..139822 | - | 1242 | WP_002288620.1 | amidohydrolase family protein | - |
| EL348_RS14560 () | 139858..140568 | - | 711 | WP_002288618.1 | GntR family transcriptional regulator | - |
| EL348_RS14565 () | 140636..141451 | - | 816 | WP_002288615.1 | fructoselysine 6-kinase | - |
| EL348_RS14570 () | 141462..142430 | - | 969 | WP_002288613.1 | SIS domain-containing protein | - |
| EL348_RS14575 () | 143240..144193 | + | 954 | WP_060797334.1 | IS30 family transposase IS1252 | Transposase |
| EL348_RS14580 () | 144902..145219 | - | 318 | WP_002290394.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| EL348_RS14585 () | 145220..145474 | - | 255 | WP_002290397.1 | AbrB family transcriptional regulator | - |
| EL348_RS14590 () | 145734..145952 | - | 219 | Protein_149 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| EL348_RS14595 () | 146408..146494 | - | 87 | Protein_150 | single-stranded DNA-binding protein | - |
| EL348_RS14600 () | 146950..148128 | + | 1179 | WP_000997695.1 | IS256 family transposase ISEf1 | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|