MGE detailed information

MGE type: Conjugative plasmid        MGE length: 202379 bp
Accession: NZ_LR130542        Location: 1..202379         Organism: Klebsiella pneumoniae strain AJ218 isolate AJ218       Replicon: plasmid 2


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EW045_RS27115 () 1..1011 + 1011 WP_004152063.1 RepB family plasmid replication initiator protein -
EW045_RS27125 () 1728..2468 - 741 WP_001515717.1 tyrosine-type recombinase/integrase -
EW045_RS27130 () 3612..4559 + 948 WP_004152065.1 sensor domain-containing diguanylate cyclase -
EW045_RS27135 () 4586..4897 - 312 WP_071527918.1 EAL domain-containing protein -
EW045_RS27145 () 4917..5885 + 969 WP_011977741.1 IS5 family transposase IS903B Transposase
EW045_RS27150 () 6558..6815 - 258 WP_004197688.1 hypothetical protein -
EW045_RS27155 () 7435..8871 + 1437 WP_080895248.1 putative cyclic di-GMP phosphodiesterase PdeB VF
EW045_RS27160 () 9854..11131 - 1278 WP_004152070.1 DUF2254 domain-containing protein -
EW045_RS27165 () 11194..13191 - 1998 WP_004178088.1 choline BCCT transporter BetT -
EW045_RS27170 () 13343..14040 - 698 Protein_9 IS1 family transposase IS1X2 Transposase
EW045_RS27180 () 15529..16013 + 485 Protein_11 IS1 family transposase IS1X2 Transposase
EW045_RS27185 () 16029..16571 + 543 Protein_12 ISL3 family transposase ISKpn25 Transposase
EW045_RS27190 () 16867..17298 - 432 WP_004178091.1 silver-binding protein SilE -
EW045_RS27195 () 17549..19024 - 1476 WP_003032875.1 copper/silver sensor histidine kinase SilS -
EW045_RS27200 () 19017..19697 - 681 WP_001572351.1 Transcriptional regulatory protein CusR VF
EW045_RS27205 () 19887..21272 + 1386 WP_000475512.1 Cation efflux system protein CusC VF
EW045_RS27210 () 21301..21654 + 354 WP_001246153.1 cation efflux system protein CusF -
EW045_RS27215 () 21768..23060 + 1293 WP_004152079.1 Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB -
EW045_RS27220 () 23071..26217 + 3147 WP_004098958.1 Cu(+)/Ag(+) efflux RND transporter permease subunit SilA -
EW045_RS27225 () 26304..26744 + 441 WP_000758228.1 hypothetical protein -
EW045_RS27230 () 26871..29318 + 2448 WP_004098955.1 Ag(+)-translocating P-type ATPase SilP -
EW045_RS27235 () 29359..29556 + 198 WP_000843497.1 DUF2933 domain-containing protein -
EW045_RS27240 () 29590..30327 - 738 WP_004118669.1 Murein DD-endopeptidase MepM VF
EW045_RS27245 () 30616..31065 - 450 WP_001023257.1 copper resistance protein -
EW045_RS27250 () 31299..33116 + 1818 WP_000925242.1 multicopper oxidase PcoA -
EW045_RS27255 () 33122..34012 + 891 WP_001378118.1 copper resistance outer membrane transporter PcoB -
EW045_RS27260 () 34052..34432 + 381 WP_000025662.1 copper resistance system metallochaperone PcoC -
EW045_RS27265 () 34437..35366 + 930 WP_004118344.1 copper resistance inner membrane protein PcoD -
EW045_RS27270 () 35421..36101 + 681 WP_001188930.1 Transcriptional activator protein CopR VF
EW045_RS27275 () 36098..37498 + 1401 WP_004152084.1 copper resistance membrane spanning protein PcoS -
EW045_RS27280 () 37715..38149 + 435 WP_004152085.1 copper resistance system metallochaperone PcoE -
EW045_RS27285 () 38381..38560 - 180 WP_004152086.1 type II toxin-antitoxin system RelE/ParE family toxin -
EW045_RS27290 () 38621..40241 - 1621 Protein_33 ISL3 family transposase -
EW045_RS27295 () 40303..40812 + 510 WP_031944101.1 aquaporin -
EW045_RS27300 () 40862..41359 - 498 WP_004152091.1 GNAT family N-acetyltransferase -
EW045_RS27305 () 41691..42017 + 327 WP_004152092.1 metalloregulator ArsR/SmtB family transcription factor -
EW045_RS27310 () 42014..42727 + 714 WP_004152093.1 arsenical resistance protein ArsH -
EW045_RS27315 () 42736..43281 + 546 WP_004182005.1 sigma-70 family RNA polymerase sigma factor -
EW045_RS27320 () 43357..43719 + 363 WP_004152095.1 arsenic metallochaperone ArsD family protein -
EW045_RS27325 () 43744..45494 + 1751 Protein_40 arsenical pump-driving ATPase -
EW045_RS27330 () 45616..46152 + 537 WP_004152096.1 GNAT family N-acetyltransferase -
EW045_RS27335 () 46185..46610 - 426 WP_004152097.1 glutaredoxin-dependent arsenate reductase -
EW045_RS27340 () 46623..47912 - 1290 WP_004152098.1 arsenite efflux transporter membrane subunit ArsB -
EW045_RS27345 () 47960..49711 - 1752 WP_004152099.1 Arsenical pump-driving ATPase VF
EW045_RS27350 () 49729..50091 - 363 WP_004152100.1 arsenite efflux transporter metallochaperone ArsD -
EW045_RS27355 () 50141..50491 - 351 WP_004152101.1 As(III)-sensing metalloregulatory transcriptional repressor ArsR -
EW045_RS27360 () 50849..51118 + 270 WP_004152102.1 hypothetical protein -
EW045_RS27365 () 51106..51681 + 576 WP_004152103.1 hypothetical protein -
EW045_RS27370 () 51712..52206 + 495 WP_004152104.1 DNA-binding protein -
EW045_RS27375 () 52250..52618 + 369 WP_004152105.1 hypothetical protein -
EW045_RS27380 () 52652..52855 + 204 WP_004152106.1 hemolysin expression modulator Hha -
EW045_RS27385 () 52904..53161 + 258 WP_004152107.1 hypothetical protein -
EW045_RS27390 () 53237..53491 + 255 WP_004152108.1 hypothetical protein -
EW045_RS27395 () 53667..53933 + 267 WP_003026799.1 DUF1778 domain-containing protein Antitoxin Detail
EW045_RS27400 () 53921..54403 + 483 WP_003026803.1 GNAT family N-acetyltransferase Toxin Detail
EW045_RS27405 () 54615..55961 + 1347 WP_020314316.1 ISNCY family transposase ISLad2 Transposase
EW045_RS27410 () 56462..57716 - 1255 Protein_57 IS3 family transposase ISKpn38 Transposase
EW045_RS27415 () 57804..58766 - 963 WP_004152113.1 M48 family metalloprotease -
EW045_RS27420 () 58753..59502 - 750 WP_009483782.1 phosphate-starvation-inducible PsiE family protein -
EW045_RS27430 () 59740..59937 - 198 WP_004152115.1 hypothetical protein -
EW045_RS27435 () 59937..62732 - 2796 WP_004152116.1 ATP-dependent Clp protease ATP-binding subunit ClpC VF
EW045_RS27440 () 62847..63416 - 570 WP_004152117.1 hypothetical protein VF
EW045_RS27445 () 63451..63732 - 282 WP_004152118.1 helix-turn-helix domain-containing protein -
EW045_RS28340 () 63976..64239 - 264 WP_004118208.1 hypothetical protein -
EW045_RS28345 () 64254..64517 + 264 WP_004118209.1 IS66 family transposase ISPpu19 Transposase
EW045_RS27455 () 64462..64578 + 117 Protein_66 transposase domain-containing protein -
EW045_RS27460 () 64763..65460 + 698 Protein_67 IS1 family transposase IS1X2 Transposase
EW045_RS27465 () 65719..66699 + 981 WP_000019473.1 IS5 family transposase ISKpn26 Transposase
EW045_RS27475 () 67281..67800 - 520 Protein_69 IS5 family transposase ISPst7 Transposase
EW045_RS27480 () 67908..68777 - 870 WP_004152692.1 HTH-type transcriptional activator CmpR VF
EW045_RS27485 () 68771..69781 - 1011 WP_004152693.1 phosphonate dehydrogenase PtxD -
EW045_RS27490 () 69790..70617 - 828 WP_129718447.1 phosphonate ABC transporter, permease protein PhnE -
EW045_RS27495 () 70626..71489 - 864 WP_004152695.1 phosphate/phosphite/phosphonate ABC transporter substrate-binding protein -
EW045_RS27500 () 71486..72313 - 828 WP_004153729.1 Glutamine transport ATP-binding protein GlnQ VF
EW045_RS27505 () 72655..72963 + 309 Protein_75 IS5 family transposase ISThi1 Transposase
EW045_RS27510 () 73169..73837 - 669 WP_044117068.1 IS6 family transposase IS26 Transposase
EW045_RS27515 () 73885..75078 - 1194 Protein_77 Tn3 family transposase TnpA_ISSba14 Transposase
EW045_RS27520 () 75141..75845 + 705 WP_004217321.1 IS6 family transposase IS26 Transposase
EW045_RS27525 () 75917..76405 + 489 Protein_79 IS110 family transposase ISKpn2 Transposase
EW045_RS27530 () 76631..76744 - 114 Protein_80 IS3 family transposase ISSen4 Transposase
EW045_RS27540 () 77014..77967 + 954 WP_001198018.1 cation diffusion facilitator family transporter -
EW045_RS27545 () 78079..78453 + 375 WP_011977761.1 hypothetical protein -
EW045_RS27550 () 78891..79472 + 582 WP_011977760.1 cytochrome b/b6 domain-containing protein -
EW045_RS27555 () 79608..80297 + 690 WP_016240364.1 VIT family protein -
EW045_RS27560 () 80440..80751 - 312 WP_011977758.1 hypothetical protein -
EW045_RS27565 () 80924..81438 + 515 Protein_86 IS3 family transposase ISEcl1 Transposase
EW045_RS27575 () 81468..81611 - 144 WP_158236233.1 hypothetical protein -
EW045_RS27580 () 81656..84628 - 2973 WP_001138073.1 Tn3 family transposase TnpA_TnAs3 Transposase
EW045_RS27585 () 84631..85188 - 558 WP_001162012.1 Tn3 family transposase TnpR_TnAs2 Transposase
EW045_RS27595 () 85510..86523 - 1014 WP_000845048.1 IS91 family transposase ISAzo26 Transposase
EW045_RS27600 () 86669..87460 + 792 WP_001206316.1 Streptomycin 3''-adenylyltransferase ARG
EW045_RS27605 () 87624..87971 + 348 WP_000679427.1 Multidrug transporter EmrE ARG
EW045_RS27610 () 87965..88804 + 840 WP_000259031.1 Dihydropteroate synthase ARG
EW045_RS27620 () 88932..89432 + 501 WP_000376623.1 GNAT family N-acetyltransferase -
EW045_RS27625 () 89608..90390 - 783 WP_001163403.1 IS21 family transposase IS1326 Transposase
EW045_RS27630 () 90380..91084 - 705 Protein_96 IS21 family transposase IS1326 Transposase
EW045_RS27635 () 91137..91841 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
EW045_RS27640 () 91853..92509 - 657 WP_000113282.1 Tetracycline repressor protein class H VF
EW045_RS27645 () 92605..93789 + 1185 WP_001039466.1 Tetracycline resistance protein, class B ARG
EW045_RS27650 () 93884..94993 + 1110 WP_000842134.1 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase -
EW045_RS27655 () 95015..95431 + 417 Protein_101 S-formylglutathione hydrolase -
EW045_RS27665 () 95483..96187 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
EW045_RS27670 () 96248..97129 + 882 Protein_103 oligosaccharide MFS transporter -
EW045_RS27675 () 97160..98248 - 1089 WP_001620097.1 AAA family ATPase -
EW045_RS27680 () 98335..98595 - 261 WP_001620096.1 hypothetical protein -
EW045_RS27685 () 98893..99753 + 861 WP_063864684.1 Beta-lactamase SHV-3 ARG
EW045_RS27690 () 99774..100535 - 762 WP_002210513.1 DeoR/GlpR family DNA-binding transcription regulator -
EW045_RS27695 () 100796..101698 + 903 WP_002903955.1 NAD(P)-dependent oxidoreductase -
EW045_RS27700 () 101710..102975 + 1266 WP_002210515.1 four-carbon acid sugar kinase family protein -
EW045_RS27705 () 102968..103588 + 621 WP_002210516.1 aldolase -
EW045_RS27710 () 103593..104246 + 654 Protein_111 2-oxo-tetronate isomerase VF
EW045_RS27715 () 104300..105004 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
EW045_RS27720 () 105583..105960 + 378 WP_004114613.1 IS66 family transposase ISSgsp1 Transposase
EW045_RS27725 () 105957..106304 + 348 WP_004152557.1 IS66 family transposase ISCfr14 Transposase
EW045_RS27730 () 106354..107891 + 1538 Protein_115 IS66 family transposase ISCfr14 Transposase
EW045_RS27735 () 107929..108306 + 378 Protein_116 IS66 family transposase ISEc22 Transposase
EW045_RS27740 () 110127..111860 - 1734 WP_004118832.1 Glutathione import ATP-binding protein GsiA VF
EW045_RS27745 () 111868..112815 - 948 WP_004118225.1 acetamidase/formamidase family protein -
EW045_RS27750 () 112860..114464 - 1605 WP_004152278.1 ABC transporter substrate-binding protein -
EW045_RS27755 () 114477..115397 - 921 WP_004118227.1 ABC transporter permease -
EW045_RS27760 () 115397..116245 - 849 WP_004152279.1 ABC transporter permease -
EW045_RS27765 () 116242..116835 - 594 WP_004118229.1 ANTAR domain-containing protein -
EW045_RS27770 () 116832..117959 - 1128 WP_004118840.1 transporter substrate-binding protein -
EW045_RS27775 () 118244..118411 - 168 WP_004118231.1 IS3 family transposase IS1400 Transposase
EW045_RS28850 () 118340..118552 + 213 WP_161989521.1 hypothetical protein -
EW045_RS27780 () 118553..119038 + 486 Protein_126 IS21 family transposase ISEc62 Transposase
EW045_RS27785 () 119514..120035 + 522 WP_004118235.1 putative RNA polymerase sigma factor FecI VF
EW045_RS27790 () 120032..120985 + 954 WP_004118237.1 fec operon regulator FecR -
EW045_RS27795 () 121071..123395 + 2325 WP_004152280.1 Fe(3+) dicitrate transport protein FecA -
EW045_RS27800 () 123440..124342 + 903 WP_004118241.1 Fe(3+) dicitrate ABC transporter substrate-binding protein FecB -
EW045_RS27805 () 124339..125337 + 999 WP_004118243.1 Fe(3+) dicitrate transport system permease protein FecC VF
EW045_RS27810 () 125334..126290 + 957 WP_004152281.1 Fe(3+) dicitrate transport system permease protein FecD VF
EW045_RS27815 () 126291..127058 + 768 WP_004152282.1 Fe(3+) dicitrate transport ATP-binding protein FecE VF
EW045_RS27820 () 127157..127450 + 294 WP_004118251.1 IS66 family transposase ISKpn24 Transposase
EW045_RS27825 () 127525..127752 + 228 Protein_135 IS66 family transposase -
EW045_RS27830 () 127781..128068 - 288 WP_165765869.1 EAL domain-containing protein -
EW045_RS27835 () 128402..129412 - 1011 WP_004152284.1 zinc-binding alcohol dehydrogenase family protein -
EW045_RS27845 () 129873..130955 + 1083 WP_004152286.1 DNA-binding transcriptional repressor LacI -
EW045_RS27850 () 131077..134151 + 3075 WP_004152287.1 beta-galactosidase -
EW045_RS27855 () 134203..135456 + 1254 WP_003846917.1 lactose permease -
EW045_RS27860 () 135548..136517 + 970 Protein_141 IS5 family transposase IS903B Transposase
EW045_RS27865 () 137162..139471 + 2310 WP_004152290.1 TerB N-terminal domain-containing protein -
EW045_RS27870 () 139475..140791 + 1317 WP_004152291.1 ATP-binding protein -
EW045_RS27875 () 140788..142983 + 2196 WP_000093087.1 DEAD/DEAH box helicase -
EW045_RS27890 () 144430..145287 - 858 WP_004152292.1 incFII family plasmid replication initiator RepA -
EW045_RS27895 () 145280..145357 - 78 WP_004171457.1 RepA leader peptide Tap -
EW045_RS27900 () 145574..145852 - 279 WP_004199332.1 replication regulatory protein RepA -
EW045_RS27905 () 146173..146652 - 480 WP_009485932.1 Phospholipase D VF
EW045_RS27910 () 146993..147271 - 279 WP_004152296.1 bacteriocin immunity protein -
EW045_RS27915 () 147273..149594 - 2322 WP_004178051.1 klebicin B-related nuclease bacteriocin -
EW045_RS27920 () 149951..150496 + 546 WP_004178052.1 hypothetical protein -
EW045_RS27925 () 150711..151058 - 348 WP_004152301.1 hypothetical protein -
EW045_RS27930 () 151078..151674 - 597 WP_004178053.1 fertility inhibition protein FinO -
EW045_RS27935 () 151832..152557 - 726 WP_004152303.1 type-F conjugative transfer system pilin acetylase TraX -
EW045_RS27940 () 152637..157898 - 5262 WP_004153029.1 Multifunctional conjugation protein TraI Relaxase
EW045_RS27945 () 157898..160207 - 2310 Protein_156 type IV conjugative transfer system coupling protein TraD -
EW045_RS27950 () 160567..161298 - 732 WP_004152629.1 complement resistance protein TraT -
EW045_RS27955 () 161488..162015 - 528 WP_004153030.1 hypothetical protein -
EW045_RS27960 () 162021..164870 - 2850 WP_004178054.1 conjugal transfer mating pair stabilization protein TraG -
EW045_RS27965 () 164870..166240 - 1371 WP_004178055.1 conjugal transfer protein TraH -
EW045_RS27970 () 166227..166655 - 429 WP_004152689.1 hypothetical protein -
EW045_RS27975 () 166648..167088 - 441 Protein_162 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
EW045_RS27980 () 167145..167842 + 698 Protein_163 IS1 family transposase IS1R Transposase
EW045_RS27985 () 167836..168066 - 231 WP_129718448.1 hypothetical protein -
EW045_RS27990 () 168059..169483 - 1425 WP_004152600.1 conjugal transfer protein TraB -
EW045_RS27995 () 169483..170223 - 741 WP_004152601.1 type-F conjugative transfer system secretin TraK -
EW045_RS28000 () 170210..170776 - 567 WP_004152602.1 type IV conjugative transfer system protein TraE -
EW045_RS28005 () 170796..171101 - 306 WP_004178059.1 type IV conjugative transfer system protein TraL -
EW045_RS28010 () 171115..171483 - 369 WP_004178060.1 type IV conjugative transfer system pilin TraA -
EW045_RS28015 () 171537..171908 - 372 WP_004208838.1 TraY domain-containing protein -
EW045_RS28020 () 171992..172678 - 687 WP_011977735.1 transcriptional regulator TraJ family protein -
EW045_RS28025 () 172901..173293 - 393 WP_004178062.1 relaxosome protein TraM -
EW045_RS28030 () 173727..174212 + 486 WP_004178063.1 hypothetical protein VF
EW045_RS28035 () 174245..174574 - 330 WP_011977736.1 hypothetical protein -
EW045_RS28040 () 174607..175428 - 822 WP_004178064.1 DUF945 domain-containing protein -
EW045_RS28060 () 176262..176675 - 414 WP_004152722.1 helix-turn-helix domain-containing protein -
EW045_RS28065 () 176676..176954 - 279 WP_004152721.1 helix-turn-helix domain-containing protein -
EW045_RS28070 () 176944..177264 - 321 WP_004152720.1 type II toxin-antitoxin system RelE/ParE family toxin -
EW045_RS28075 () 177345..177569 - 225 WP_004152719.1 hypothetical protein -
EW045_RS28080 () 177580..177792 - 213 WP_004152718.1 hypothetical protein -
EW045_RS28085 () 177853..178209 - 357 WP_004152717.1 hypothetical protein -
EW045_RS28095 () 178845..179195 - 351 WP_004152758.1 hypothetical protein -
EW045_RS28100 () 179192..179464 - 273 WP_004152759.1 hypothetical protein -
EW045_RS28105 () 180164..180325 - 162 WP_004118124.1 type I toxin-antitoxin system Hok family toxin -
EW045_RS28110 () 180397..181476 + 1080 WP_004220208.1 IS481 family transposase ISKpn28 Transposase
EW045_RS28120 () 181654..182028 - 375 WP_004152638.1 hypothetical protein -
EW045_RS28125 () 182084..182410 - 327 WP_004152639.1 hypothetical protein -
EW045_RS28130 () 182407..183135 - 729 WP_004152640.1 plasmid SOS inhibition protein A -
EW045_RS28135 () 183132..183563 - 432 WP_004152641.1 conjugation system SOS inhibitor PsiB -
EW045_RS28140 () 183630..185666 - 2037 WP_004178066.1 ParB/RepB/Spo0J family partition protein -
EW045_RS28145 () 185736..185984 - 249 WP_004152643.1 DUF905 domain-containing protein -
EW045_RS28150 () 186033..186575 - 543 WP_004152644.1 single-stranded DNA-binding protein -
EW045_RS28165 () 187351..187914 - 564 WP_004152645.1 methyltransferase -
EW045_RS28170 () 187962..189317 - 1356 WP_004178068.1 DUF3560 domain-containing protein -
EW045_RS28175 () 189369..189599 - 231 WP_004198570.1 hypothetical protein -
EW045_RS28180 () 189691..189918 - 228 WP_004178072.1 hypothetical protein -
EW045_RS28190 () 190700..191017 - 318 WP_004118473.1 hypothetical protein -
EW045_RS28195 () 191052..191306 - 255 WP_004152754.1 DNA polymerase III subunit theta -
EW045_RS28200 () 191543..191968 - 426 WP_004118478.1 antirestriction protein -
EW045_RS28210 () 192489..192719 - 231 WP_004152753.1 hypothetical protein -
EW045_RS28215 () 192953..194440 - 1488 WP_004178082.1 group II intron reverse transcriptase/maturase -
EW045_RS28225 () 194843..195268 + 426 WP_004178083.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
EW045_RS28230 () 195268..196539 + 1272 WP_004152715.1 Y-family DNA polymerase -
EW045_RS28235 () 196618..196833 + 216 Protein_204 type II toxin-antitoxin system Phd/YefM family antitoxin -
EW045_RS28240 () 196856..198054 - 1199 Protein_205 IS200-IS605 family transposase IS609 Transposase
EW045_RS28255 () 199491..200462 - 972 WP_004152062.1 ParB/RepB/Spo0J family plasmid partition protein -
EW045_RS28260 () 200462..201628 - 1167 WP_000523813.1 hypothetical protein VF

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance