MGE detailed information
MGE type: Conjugative plasmid MGE length: 100423 bp
Accession: NZ_CP119738 Location: 1..100423 Organism: Escherichia coli strain E92 Replicon: plasmid pE92-4
Accession: NZ_CP119738 Location: 1..100423 Organism: Escherichia coli strain E92 Replicon: plasmid pE92-4
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| P1J22_RS28005 (P1J22_28005) | 32..373 | - | 342 | WP_023909256.1 | 60 kDa chaperonin | VF |
| P1J22_RS28010 (P1J22_28010) | 334..783 | - | 450 | WP_013362817.1 | hypothetical protein | - |
| P1J22_RS28015 (P1J22_28015) | 1413..2150 | - | 738 | WP_013362818.1 | rRNA adenine N-6-methyltransferase | ARG |
| P1J22_RS28020 (P1J22_28020) | 2276..2371 | - | 96 | WP_013362819.1 | 23S rRNA methyltransferase attenuation leader peptide | - |
| P1J22_RS28025 (P1J22_28025) | 2506..3210 | + | 705 | WP_001067834.1 | IS6 family transposase IS26 | Transposase |
| P1J22_RS28030 (P1J22_28030) | 3332..4237 | + | 906 | WP_000219391.1 | hypothetical protein | ARG |
| P1J22_RS28035 (P1J22_28035) | 4234..5472 | + | 1239 | WP_000004159.1 | macrolide resistance MFS transporter Mrx(A) | - |
| P1J22_RS28040 (P1J22_28040) | 5472..5684 | + | 213 | Protein_7 | macrolide-binding transcriptional repressor MphR(A) | - |
| P1J22_RS28045 (P1J22_28045) | 5738..6442 | - | 705 | WP_001067845.1 | IS6 family transposase IS26 | Transposase |
| P1J22_RS28050 (P1J22_28050) | 6467..6991 | + | 525 | WP_050195267.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| P1J22_RS28055 (P1J22_28055) | 7068..8459 | + | 1392 | WP_000085084.1 | SIR2 family protein | - |
| P1J22_RS28060 (P1J22_28060) | 8456..10528 | + | 2073 | WP_001084041.1 | DUF87 domain-containing protein | - |
| P1J22_RS28065 (P1J22_28065) | 10718..10957 | - | 240 | WP_000371884.1 | hypothetical protein | - |
| P1J22_RS28070 (P1J22_28070) | 11125..11802 | + | 678 | WP_001339397.1 | IS66 family transposase ISCro1 | Transposase |
| P1J22_RS28075 (P1J22_28075) | 11802..12149 | + | 348 | WP_000624622.1 | IS66 family transposase ISCro1 | Transposase |
| P1J22_RS28080 (P1J22_28080) | 12169..13740 | + | 1572 | WP_029392005.1 | IS66 family transposase ISCro1 | Transposase |
| P1J22_RS28085 (P1J22_28085) | 13939..14430 | + | 492 | WP_000528930.1 | HEPN family nuclease | - |
| P1J22_RS28090 (P1J22_28090) | 14442..15200 | + | 759 | WP_000494510.1 | hypothetical protein | - |
| P1J22_RS28095 (P1J22_28095) | 15491..17014 | + | 1524 | WP_000921251.1 | hypothetical protein | - |
| P1J22_RS28100 (P1J22_28100) | 17049..18173 | + | 1125 | WP_000386705.1 | DUF4238 domain-containing protein | - |
| P1J22_RS28105 (P1J22_28105) | 18173..18463 | + | 291 | WP_000648897.1 | hypothetical protein | - |
| P1J22_RS28110 (P1J22_28110) | 18845..19768 | - | 924 | WP_001118645.1 | IS5 family transposase IS903B | Transposase |
| P1J22_RS28115 (P1J22_28115) | 20101..21102 | + | 1002 | WP_000785695.1 | DUF4238 domain-containing protein | - |
| P1J22_RS28120 (P1J22_28120) | 21276..21620 | - | 345 | WP_000792769.1 | hypothetical protein | - |
| P1J22_RS28125 (P1J22_28125) | 22118..22372 | - | 255 | WP_000678528.1 | hypothetical protein | - |
| P1J22_RS28130 (P1J22_28130) | 22422..23348 | - | 927 | WP_001290414.1 | hypothetical protein | - |
| P1J22_RS28135 (P1J22_28135) | 23907..24125 | + | 219 | WP_000813634.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| P1J22_RS28140 (P1J22_28140) | 24127..24432 | + | 306 | WP_001159871.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| P1J22_RS28145 (P1J22_28145) | 24433..25242 | + | 810 | WP_000016963.1 | site-specific integrase | - |
| P1J22_RS28150 (P1J22_28150) | 25414..25608 | + | 195 | Protein_29 | colicin M immunity protein | - |
| P1J22_RS28155 (P1J22_28155) | 25664..26361 | + | 698 | WP_223200906.1 | IS1 family transposase IS1R | Transposase |
| P1J22_RS28160 (P1J22_28160) | 26377..26967 | - | 591 | Protein_31 | colicin-like bacteriocin tRNase domain-containing protein | - |
| P1J22_RS28165 (P1J22_28165) | 27147..27573 | + | 427 | Protein_32 | tyrosine-type recombinase/integrase | - |
| P1J22_RS28170 (P1J22_28170) | 27765..28040 | - | 276 | WP_000239529.1 | hypothetical protein | - |
| P1J22_RS28175 (P1J22_28175) | 28034..28678 | - | 645 | WP_000633913.1 | division plane positioning ATPase MipZ | - |
| P1J22_RS28180 (P1J22_28180) | 28907..29878 | + | 972 | WP_001103697.1 | plasmid segregation protein ParM | - |
| P1J22_RS28185 (P1J22_28185) | 29883..30275 | + | 393 | WP_000340829.1 | plasmid partitioning/stability family protein | - |
| P1J22_RS28190 (P1J22_28190) | 30280..31551 | - | 1272 | WP_000457496.1 | Y-family DNA polymerase | - |
| P1J22_RS28195 (P1J22_28195) | 31551..31988 | - | 438 | WP_000109071.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| P1J22_RS28200 (P1J22_28200) | 31985..32233 | - | 249 | WP_000618110.1 | DinI-like family protein | - |
| P1J22_RS28205 (P1J22_28205) | 32651..33553 | + | 903 | WP_001302618.1 | DUF1281 domain-containing protein | - |
| P1J22_RS28210 (P1J22_28210) | 33557..33862 | + | 306 | WP_032155763.1 | hypothetical protein | - |
| P1J22_RS28215 (P1J22_28215) | 33938..34621 | + | 684 | WP_000086160.1 | DNA methylase | - |
| P1J22_RS28220 (P1J22_28220) | 34622..34843 | + | 222 | WP_001104887.1 | hypothetical protein | - |
| P1J22_RS28225 (P1J22_28225) | 34803..35289 | + | 487 | Protein_44 | DUF1380 family protein | - |
| P1J22_RS28230 (P1J22_28230) | 35334..36104 | + | 771 | WP_001006225.1 | hypothetical protein | - |
| P1J22_RS28235 (P1J22_28235) | 36518..36943 | + | 426 | WP_089079046.1 | antirestriction protein | - |
| P1J22_RS28240 (P1J22_28240) | 36990..37412 | + | 423 | WP_000271762.1 | DUF1380 family protein | - |
| P1J22_RS28245 (P1J22_28245) | 37409..37600 | + | 192 | WP_001027495.1 | hypothetical protein | - |
| P1J22_RS28250 (P1J22_28250) | 37914..39581 | - | 1668 | WP_052991863.1 | group II intron reverse transcriptase/maturase | - |
| P1J22_RS28255 (P1J22_28255) | 40310..40464 | - | 155 | Protein_50 | hypothetical protein | - |
| P1J22_RS28260 (P1J22_28260) | 40981..41211 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| P1J22_RS28265 (P1J22_28265) | 41263..42624 | + | 1362 | WP_000170695.1 | DUF3560 domain-containing protein | - |
| P1J22_RS28270 (P1J22_28270) | 42671..43234 | + | 564 | WP_001298559.1 | class I SAM-dependent methyltransferase | - |
| P1J22_RS28275 (P1J22_28275) | 43320..43769 | - | 450 | Protein_54 | hypothetical protein | - |
| P1J22_RS28280 (P1J22_28280) | 44069..44365 | + | 297 | WP_001272251.1 | hypothetical protein | - |
| P1J22_RS28285 (P1J22_28285) | 44476..45297 | + | 822 | WP_001234445.1 | DUF932 domain-containing protein | - |
| P1J22_RS28290 (P1J22_28290) | 45594..46184 | - | 591 | WP_000252683.1 | hypothetical protein | VF |
| P1J22_RS28295 (P1J22_28295) | 46519..46902 | + | 384 | WP_001354030.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| P1J22_RS28300 (P1J22_28300) | 47096..47767 | + | 672 | WP_000283561.1 | conjugal transfer transcriptional regulator TraJ | - |
| P1J22_RS28305 (P1J22_28305) | 47904..48131 | + | 228 | WP_000089263.1 | conjugal transfer relaxosome protein TraY | - |
| P1J22_RS28310 (P1J22_28310) | 48164..48523 | + | 360 | WP_001098992.1 | type IV conjugative transfer system pilin TraA | - |
| P1J22_RS28315 (P1J22_28315) | 48538..48849 | + | 312 | WP_000012113.1 | type IV conjugative transfer system protein TraL | - |
| P1J22_RS28320 (P1J22_28320) | 48871..49437 | + | 567 | WP_000399793.1 | type IV conjugative transfer system protein TraE | - |
| P1J22_RS28325 (P1J22_28325) | 49424..50152 | + | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
| P1J22_RS28330 (P1J22_28330) | 50152..51603 | + | 1452 | WP_000146675.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| P1J22_RS28335 (P1J22_28335) | 51593..52159 | + | 567 | WP_000896599.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| P1J22_RS28340 (P1J22_28340) | 52146..52466 | + | 321 | WP_001057307.1 | conjugal transfer protein TrbD | - |
| P1J22_RS28345 (P1J22_28345) | 52463..52978 | + | 516 | WP_000809881.1 | type IV conjugative transfer system lipoprotein TraV | - |
| P1J22_RS28350 (P1J22_28350) | 53113..53334 | + | 222 | WP_001278683.1 | conjugal transfer protein TraR | - |
| P1J22_RS28355 (P1J22_28355) | 53370..54338 | + | 969 | WP_000654804.1 | IS5 family transposase IS903B | Transposase |
| P1J22_RS28360 (P1J22_28360) | 54378..54806 | + | 429 | WP_089438737.1 | hypothetical protein | - |
| P1J22_RS28365 (P1J22_28365) | 54799..55272 | + | 474 | WP_000549568.1 | hypothetical protein | - |
| P1J22_RS28370 (P1J22_28370) | 55352..55570 | + | 219 | WP_000556745.1 | hypothetical protein | - |
| P1J22_RS28375 (P1J22_28375) | 55598..55945 | + | 348 | WP_000836682.1 | hypothetical protein | - |
| P1J22_RS28380 (P1J22_28380) | 56071..58701 | + | 2631 | WP_000069777.1 | type IV secretion system protein TraC | - |
| P1J22_RS28385 (P1J22_28385) | 58698..59084 | + | 387 | WP_000214084.1 | type-F conjugative transfer system protein TrbI | - |
| P1J22_RS28390 (P1J22_28390) | 59081..59713 | + | 633 | WP_094885485.1 | type-F conjugative transfer system protein TraW | - |
| P1J22_RS28395 (P1J22_28395) | 59710..60702 | + | 993 | WP_000830838.1 | conjugal transfer pilus assembly protein TraU | - |
| P1J22_RS28400 (P1J22_28400) | 60732..61037 | + | 306 | WP_000224416.1 | hypothetical protein | - |
| P1J22_RS28405 (P1J22_28405) | 61046..61684 | + | 639 | WP_001080256.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| P1J22_RS28410 (P1J22_28410) | 61681..63531 | + | 1851 | WP_000821856.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| P1J22_RS28415 (P1J22_28415) | 63558..63815 | + | 258 | WP_000864353.1 | conjugal transfer protein TrbE | - |
| P1J22_RS28420 (P1J22_28420) | 63808..64551 | + | 744 | WP_001030371.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| P1J22_RS28425 (P1J22_28425) | 64565..64909 | + | 345 | WP_000556796.1 | conjugal transfer protein TrbA | - |
| P1J22_RS28430 (P1J22_28430) | 65028..65312 | + | 285 | WP_000624194.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| P1J22_RS28435 (P1J22_28435) | 65299..65844 | + | 546 | WP_000059831.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| P1J22_RS28440 (P1J22_28440) | 65774..66121 | + | 348 | WP_001309242.1 | P-type conjugative transfer protein TrbJ | - |
| P1J22_RS28445 (P1J22_28445) | 66102..66494 | + | 393 | WP_000660699.1 | F-type conjugal transfer protein TrbF | - |
| P1J22_RS28450 (P1J22_28450) | 66481..67854 | + | 1374 | WP_000944331.1 | conjugal transfer pilus assembly protein TraH | - |
| P1J22_RS28455 (P1J22_28455) | 67851..70673 | + | 2823 | WP_001007039.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| P1J22_RS28460 (P1J22_28460) | 70689..71174 | + | 486 | WP_000605870.1 | hypothetical protein | - |
| P1J22_RS28465 (P1J22_28465) | 71223..71954 | + | 732 | WP_000782451.1 | conjugal transfer complement resistance protein TraT | - |
| P1J22_RS28470 (P1J22_28470) | 72157..72894 | + | 738 | WP_000199905.1 | hypothetical protein | - |
| P1J22_RS28475 (P1J22_28475) | 72945..75251 | + | 2307 | WP_099004446.1 | Coupling protein TraD | VF |
| P1J22_RS28480 (P1J22_28480) | 75251..80521 | + | 5271 | WP_000948354.1 | Multifunctional conjugation protein TraI | Relaxase |
| P1J22_RS28485 (P1J22_28485) | 80541..81287 | + | 747 | WP_000205725.1 | conjugal transfer pilus acetylase TraX | - |
| P1J22_RS28490 (P1J22_28490) | 81346..82206 | + | 861 | WP_000704523.1 | Quorum-quenching protein AidA | VF |
| P1J22_RS28495 (P1J22_28495) | 82309..82869 | + | 561 | WP_000139323.1 | fertility inhibition protein FinO | - |
| P1J22_RS28500 (P1J22_28500) | 82998..83210 | + | 213 | WP_001309245.1 | ANR family transcriptional regulator | - |
| P1J22_RS28505 (P1J22_28505) | 83455..83916 | + | 462 | WP_001233838.1 | thermonuclease family protein | - |
| P1J22_RS28510 (P1J22_28510) | 83962..84171 | + | 210 | WP_001298565.1 | hemolysin expression modulator Hha | - |
| P1J22_RS28515 (P1J22_28515) | 84209..84799 | + | 591 | WP_000766807.1 | DUF2726 domain-containing protein | - |
| P1J22_RS28520 (P1J22_28520) | 85039..85293 | + | 255 | WP_000083830.1 | replication regulatory protein RepA | - |
| P1J22_RS28525 (P1J22_28525) | 85531..85605 | + | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| P1J22_RS28530 (P1J22_28530) | 85598..86455 | + | 858 | WP_000130646.1 | incFII family plasmid replication initiator RepA | - |
| P1J22_RS28535 (P1J22_28535) | 87394..88047 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| P1J22_RS28540 (P1J22_28540) | 88140..88397 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| P1J22_RS28545 (P1J22_28545) | 88330..88731 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| P1J22_RS28550 (P1J22_28550) | 88980..89677 | + | 698 | WP_095033700.1 | IS1 family transposase IS1R | Transposase |
| P1J22_RS28555 (P1J22_28555) | 89784..90218 | - | 435 | WP_000429836.1 | IS607 family transposase ISChh1 | Transposase |
| P1J22_RS28560 (P1J22_28560) | 90290..90640 | + | 351 | WP_001294663.1 | mercuric transport protein MerT | - |
| P1J22_RS28565 (P1J22_28565) | 90654..90929 | + | 276 | WP_000732292.1 | mercury resistance system periplasmic binding protein MerP | - |
| P1J22_RS28570 (P1J22_28570) | 90965..91387 | + | 423 | WP_001340589.1 | organomercurial transporter MerC | - |
| P1J22_RS28575 (P1J22_28575) | 91439..93133 | + | 1695 | WP_000105636.1 | mercury(II) reductase | - |
| P1J22_RS28580 (P1J22_28580) | 93151..93513 | + | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| P1J22_RS28585 (P1J22_28585) | 93510..93746 | + | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| P1J22_RS28590 (P1J22_28590) | 93782..94450 | + | 669 | WP_001300294.1 | putative signaling protein | VF |
| P1J22_RS28595 (P1J22_28595) | 94525..95775 | + | 1251 | Protein_118 | transposase | - |
| P1J22_RS28600 (P1J22_28600) | 95840..96544 | + | 705 | WP_001067834.1 | IS6 family transposase IS26 | Transposase |
| P1J22_RS28605 (P1J22_28605) | 96867..97859 | - | 993 | WP_276171336.1 | IS91 family transposase ISVsa3 | Transposase |
| P1J22_RS28610 (P1J22_28610) | 98087..99274 | - | 1188 | WP_276171320.1 | IS91 family transposase IS91 | Transposase |
| P1J22_RS28615 (P1J22_28615) | 99274..99639 | - | 366 | WP_000124096.1 | hypothetical protein | - |
| P1J22_RS28620 (P1J22_28620) | 99743..100180 | - | 438 | Protein_123 | transposase zinc-binding domain-containing protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|