MGE detailed information
MGE type: Conjugative plasmid MGE length: 114748 bp
Accession: NZ_CP096232 Location: 1..114748 Organism: Klebsiella pneumoniae subsp. pneumoniae strain H39 Replicon: plasmid pKPC-H39
Accession: NZ_CP096232 Location: 1..114748 Organism: Klebsiella pneumoniae subsp. pneumoniae strain H39 Replicon: plasmid pKPC-H39
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| M0538_RS27505 (19) | 19..894 | + | 876 | WP_004098982.1 | replication initiation protein | - |
| M0538_RS27510 (1551) | 1551..2177 | + | 627 | WP_004197649.1 | Chromosome-partitioning ATPase Soj | VF |
| M0538_RS27515 (2174) | 2174..2476 | + | 303 | WP_004197636.1 | hypothetical protein | - |
| M0538_RS27520 (2972) | 2972..3766 | - | 795 | WP_004197635.1 | site-specific integrase | - |
| M0538_RS27525 (3964) | 3964..4980 | - | 1017 | WP_017899884.1 | hypothetical protein | - |
| M0538_RS27530 (4991) | 4991..5305 | - | 315 | WP_053389906.1 | hypothetical protein | - |
| M0538_RS27535 (5332) | 5332..5727 | - | 396 | WP_017899885.1 | hypothetical protein | - |
| M0538_RS27540 (5896) | 5896..6201 | - | 306 | WP_013023785.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| M0538_RS27545 (6203) | 6203..6421 | - | 219 | WP_001568025.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| M0538_RS27550 (6591) | 6591..7052 | - | 462 | WP_160866775.1 | hypothetical protein | - |
| M0538_RS27555 (7009) | 7009..7239 | + | 231 | WP_001261282.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| M0538_RS27560 (7236) | 7236..7652 | + | 417 | WP_001044770.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| M0538_RS27565 (7726) | 7726..7944 | + | 219 | Protein_12 | AAA family ATPase | - |
| M0538_RS27570 (7998) | 7998..8702 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| M0538_RS27575 (8839) | 8839..9699 | + | 861 | WP_002904004.1 | Beta-lactamase SHV-2 | ARG |
| M0538_RS27580 (9720) | 9720..10481 | - | 762 | WP_002210513.1 | DeoR/GlpR family DNA-binding transcription regulator | - |
| M0538_RS27585 (10743) | 10743..11645 | + | 903 | WP_002903955.1 | NAD(P)-dependent oxidoreductase | - |
| M0538_RS27590 (11657) | 11657..12909 | + | 1253 | Protein_17 | four-carbon acid sugar kinase family protein | - |
| M0538_RS27595 (12902) | 12902..13237 | + | 336 | Protein_18 | class II aldolase/adducin family protein | - |
| M0538_RS27600 (13292) | 13292..13996 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| M0538_RS27605 (14229) | 14229..15089 | + | 861 | WP_000557454.1 | SPBc2 prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD | ARG |
| M0538_RS27610 (15102) | 15102..15644 | + | 543 | WP_000587837.1 | AAA family ATPase | - |
| M0538_RS27615 (16126) | 16126..16317 | - | 192 | WP_000951934.1 | hypothetical protein | - |
| M0538_RS27620 (16341) | 16341..16568 | + | 228 | WP_000248278.1 | hypothetical protein | - |
| M0538_RS27625 (16619) | 16619..17755 | + | 1137 | WP_000080861.1 | DUF3883 domain-containing protein | - |
| M0538_RS27630 (17870) | 17870..19240 | + | 1371 | WP_000971921.1 | IS1182 family transposase ISCfr1 | Transposase |
| M0538_RS27635 (20061) | 20061..20921 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| M0538_RS27640 (21447) | 21447..22451 | - | 1005 | WP_000427619.1 | IS110 family transposase IS5075 | Transposase |
| M0538_RS27645 (22530) | 22530..22964 | - | 435 | WP_000429836.1 | IS607 family transposase ISChh1 | Transposase |
| M0538_RS27650 (23036) | 23036..23386 | + | 351 | WP_001294663.1 | mercuric transport protein MerT | - |
| M0538_RS27655 (23400) | 23400..23675 | + | 276 | WP_000732292.1 | mercury resistance system periplasmic binding protein MerP | - |
| M0538_RS27660 (23711) | 23711..24133 | + | 423 | WP_001340589.1 | organomercurial transporter MerC | - |
| M0538_RS27665 (24185) | 24185..25879 | + | 1695 | WP_000105636.1 | mercury(II) reductase | - |
| M0538_RS27670 (25897) | 25897..26259 | + | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| M0538_RS27675 (26256) | 26256..26492 | + | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| M0538_RS27680 (26528) | 26528..27196 | + | 669 | WP_001300294.1 | putative signaling protein | VF |
| M0538_RS27685 (27271) | 27271..28521 | + | 1251 | Protein_36 | transposase | - |
| M0538_RS27690 (28586) | 28586..29290 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| M0538_RS27695 (29342) | 29342..29803 | + | 462 | Protein_38 | Tn3 family transposase TnpR_Tn3 | Transposase |
| M0538_RS27700 (29926) | 29926..30906 | + | 981 | WP_013213985.1 | IS481 family transposase ISKpn27 | Transposase |
| M0538_RS27705 (31182) | 31182..32063 | + | 882 | WP_004199234.1 | Carbapenem-hydrolyzing beta-lactamase KPC | ARG |
| M0538_RS27710 (32313) | 32313..33194 | - | 882 | Protein_41 | IS1182 family transposase ISKpn6 | Transposase |
| M0538_RS27715 (33298) | 33298..33594 | - | 297 | WP_013213987.1 | transcriptional regulator | - |
| M0538_RS27720 (33640) | 33640..33795 | - | 156 | WP_013213988.1 | hypothetical protein | - |
| M0538_RS27725 (33923) | 33923..34348 | - | 426 | WP_013213989.1 | antirestriction protein | - |
| M0538_RS27730 (34459) | 34459..34737 | - | 279 | WP_013213990.1 | hypothetical protein | - |
| M0538_RS27735 (35271) | 35271..35888 | - | 618 | Protein_46 | replication protein | - |
| M0538_RS27740 (36280) | 36280..36840 | + | 561 | WP_001161490.1 | Tn3 family transposase TnpR_TnAs1 | Transposase |
| M0538_RS27745 (36844) | 36844..39810 | + | 2967 | WP_001138014.1 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| M0538_RS27750 (39844) | 39844..40146 | + | 303 | Protein_49 | IS6 family transposase IS26 | Transposase |
| M0538_RS27755 (40348) | 40348..40821 | - | 474 | WP_013213991.1 | GNAT family N-acetyltransferase | - |
| M0538_RS27760 (41241) | 41241..41753 | - | 513 | Protein_51 | ISL3 family transposase ISEc38 | Transposase |
| M0538_RS27765 (41757) | 41757..42089 | - | 333 | WP_013213994.1 | hypothetical protein | - |
| M0538_RS27770 (42475) | 42475..43386 | - | 912 | WP_013213995.1 | hypothetical protein | - |
| M0538_RS27775 (43438) | 43438..45380 | - | 1943 | Protein_54 | hypothetical protein | - |
| M0538_RS27780 (45384) | 45384..46277 | - | 894 | WP_013213999.1 | hypothetical protein | - |
| M0538_RS27785 (46285) | 46285..47547 | - | 1263 | WP_014343474.1 | N-6 DNA methylase | - |
| M0538_RS27790 (48846) | 48846..49721 | - | 876 | WP_072101968.1 | incFII family plasmid replication initiator RepA | - |
| M0538_RS27795 (50019) | 50019..50276 | - | 258 | WP_015344940.1 | replication regulatory protein RepA | - |
| M0538_RS27800 (50408) | 50408..50959 | - | 552 | WP_015344941.1 | Phospholipase D | VF |
| M0538_RS27805 (51063) | 51063..51371 | - | 309 | WP_004152383.1 | hypothetical protein | - |
| M0538_RS27810 (51368) | 51368..52018 | - | 651 | WP_014343480.1 | DUF2726 domain-containing protein | - |
| M0538_RS27815 (52074) | 52074..52718 | - | 645 | WP_004153014.1 | hypothetical protein | - |
| M0538_RS27820 (52768) | 52768..53370 | - | 603 | WP_013023836.1 | PIN domain-containing protein | - |
| M0538_RS27825 (53531) | 53531..54124 | - | 594 | WP_015344942.1 | fertility inhibition protein FinO | - |
| M0538_RS27830 (54196) | 54196..54921 | - | 726 | WP_015344943.1 | type-F conjugative transfer system pilin acetylase TraX | - |
| M0538_RS27835 (54965) | 54965..60226 | - | 5262 | WP_064291677.1 | Multifunctional conjugation protein TraI | Relaxase |
| M0538_RS27840 (60226) | 60226..62538 | - | 2313 | WP_072101984.1 | type IV conjugative transfer system coupling protein TraD | - |
| M0538_RS27845 (62667) | 62667..63356 | - | 690 | WP_072101983.1 | hypothetical protein | - |
| M0538_RS27850 (63549) | 63549..64280 | - | 732 | WP_004152629.1 | conjugal transfer complement resistance protein TraT | - |
| M0538_RS27855 (64466) | 64466..64999 | - | 534 | WP_014343486.1 | conjugal transfer protein TraS | - |
| M0538_RS27860 (65002) | 65002..67851 | - | 2850 | WP_013609534.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| M0538_RS27865 (67851) | 67851..69230 | - | 1380 | WP_014343487.1 | conjugal transfer pilus assembly protein TraH | - |
| M0538_RS27870 (69208) | 69208..69651 | - | 444 | WP_004194305.1 | F-type conjugal transfer protein TrbF | - |
| M0538_RS27875 (69697) | 69697..70254 | - | 558 | WP_013214031.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| M0538_RS27880 (70226) | 70226..70465 | - | 240 | WP_004144400.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| M0538_RS27885 (70476) | 70476..71228 | - | 753 | WP_004152677.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| M0538_RS27890 (71249) | 71249..71575 | - | 327 | WP_004152676.1 | hypothetical protein | - |
| M0538_RS27895 (71588) | 71588..71836 | - | 249 | WP_004152675.1 | hypothetical protein | - |
| M0538_RS27900 (71814) | 71814..72068 | - | 255 | WP_004152674.1 | conjugal transfer protein TrbE | - |
| M0538_RS27905 (72100) | 72100..74055 | - | 1956 | WP_030003482.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| M0538_RS27910 (74114) | 74114..74752 | - | 639 | WP_069985712.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| M0538_RS27915 (74765) | 74765..75754 | - | 990 | WP_029497420.1 | conjugal transfer pilus assembly protein TraU | - |
| M0538_RS27920 (75751) | 75751..76152 | - | 402 | WP_004194979.1 | hypothetical protein | - |
| M0538_RS27925 (76187) | 76187..76822 | - | 636 | WP_029497419.1 | type-F conjugative transfer system protein TraW | - |
| M0538_RS27930 (76822) | 76822..77211 | - | 390 | WP_004167468.1 | type-F conjugative transfer system protein TrbI | - |
| M0538_RS27935 (77211) | 77211..79850 | - | 2640 | WP_013214024.1 | type IV secretion system protein TraC | - |
| M0538_RS27940 (79922) | 79922..80320 | - | 399 | WP_023179972.1 | hypothetical protein | - |
| M0538_RS27945 (80699) | 80699..81103 | - | 405 | WP_004197817.1 | hypothetical protein | - |
| M0538_RS27950 (81170) | 81170..81481 | - | 312 | WP_029497417.1 | hypothetical protein | - |
| M0538_RS27955 (81482) | 81482..81700 | - | 219 | WP_004195468.1 | hypothetical protein | - |
| M0538_RS27960 (82023) | 82023..82607 | - | 585 | WP_032440547.1 | type IV conjugative transfer system lipoprotein TraV | - |
| M0538_RS27965 (82680) | 82680..84104 | - | 1425 | WP_004194260.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| M0538_RS27970 (84104) | 84104..84844 | - | 741 | WP_013023821.1 | type-F conjugative transfer system secretin TraK | - |
| M0538_RS27975 (84831) | 84831..85397 | - | 567 | WP_004144423.1 | type IV conjugative transfer system protein TraE | - |
| M0538_RS27980 (85417) | 85417..85722 | - | 306 | WP_004144424.1 | type IV conjugative transfer system protein TraL | - |
| M0538_RS27985 (85736) | 85736..86104 | - | 369 | WP_004194426.1 | type IV conjugative transfer system pilin TraA | - |
| M0538_RS27990 (86173) | 86173..86373 | - | 201 | WP_004194116.1 | TraY domain-containing protein | - |
| M0538_RS27995 (86459) | 86459..87160 | - | 702 | WP_004194113.1 | hypothetical protein | - |
| M0538_RS28000 (87390) | 87390..87782 | - | 393 | WP_004194114.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| M0538_RS28005 (88214) | 88214..88699 | + | 486 | WP_032440470.1 | hypothetical protein | VF |
| M0538_RS28010 (88732) | 88732..89061 | - | 330 | WP_071994324.1 | DUF5983 family protein | - |
| M0538_RS28015 (89094) | 89094..89915 | - | 822 | WP_023287138.1 | DUF932 domain-containing protein | - |
| M0538_RS28020 (90745) | 90745..91158 | - | 414 | WP_069985713.1 | helix-turn-helix domain-containing protein | - |
| M0538_RS28025 (91159) | 91159..91437 | - | 279 | WP_004152721.1 | helix-turn-helix transcriptional regulator | - |
| M0538_RS28030 (91427) | 91427..91747 | - | 321 | WP_004152720.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| M0538_RS28035 (91828) | 91828..92052 | - | 225 | WP_014343499.1 | hypothetical protein | - |
| M0538_RS28040 (92063) | 92063..92275 | - | 213 | WP_019706020.1 | hypothetical protein | - |
| M0538_RS28045 (92336) | 92336..92692 | - | 357 | WP_019706019.1 | hypothetical protein | - |
| M0538_RS28050 (93324) | 93324..93674 | - | 351 | WP_023287104.1 | hypothetical protein | - |
| M0538_RS28055 (93671) | 93671..93943 | - | 273 | WP_023287105.1 | hypothetical protein | - |
| M0538_RS28060 (94637) | 94637..94735 | - | 99 | WP_159224797.1 | Hok/Gef family protein | - |
| M0538_RS28065 (94710) | 94710..94766 | - | 57 | Protein_112 | modulator protein | - |
| M0538_RS28070 (94865) | 94865..95938 | + | 1074 | WP_048270288.1 | IS481 family transposase ISKpn28 | Transposase |
| - (95938) | 95938..96062 | - | 125 | NuclAT_0 | - | - |
| - (95938) | 95938..96062 | - | 125 | NuclAT_0 | - | - |
| - (95938) | 95938..96062 | - | 125 | NuclAT_0 | - | - |
| - (95938) | 95938..96062 | - | 125 | NuclAT_0 | - | - |
| M0538_RS28075 (96122) | 96122..96496 | - | 375 | WP_023287106.1 | hypothetical protein | - |
| M0538_RS28080 (96552) | 96552..96878 | - | 327 | WP_001568059.1 | hypothetical protein | - |
| M0538_RS28085 (96875) | 96875..97603 | - | 729 | WP_001568058.1 | plasmid SOS inhibition protein A | - |
| M0538_RS28090 (97600) | 97600..98031 | - | 432 | WP_001568057.1 | conjugation system SOS inhibitor PsiB | - |
| M0538_RS28095 (98076) | 98076..100133 | - | 2058 | WP_023287107.1 | ParB/RepB/Spo0J family partition protein | - |
| M0538_RS28100 (100203) | 100203..100451 | - | 249 | WP_009310026.1 | DUF905 domain-containing protein | - |
| M0538_RS28105 (100500) | 100500..101042 | - | 543 | WP_015065513.1 | single-stranded DNA-binding protein | - |
| M0538_RS28110 (101873) | 101873..102436 | - | 564 | WP_004152756.1 | methyltransferase | - |
| M0538_RS28115 (102484) | 102484..103839 | - | 1356 | WP_013054814.1 | DUF3560 domain-containing protein | - |
| M0538_RS28120 (103891) | 103891..104121 | - | 231 | WP_001568051.1 | hypothetical protein | - |
| M0538_RS28125 (104213) | 104213..104440 | - | 228 | WP_001568050.1 | hypothetical protein | - |
| M0538_RS28130 (105183) | 105183..105503 | - | 321 | WP_032436760.1 | hypothetical protein | - |
| M0538_RS28135 (105538) | 105538..105792 | - | 255 | WP_011977779.1 | DNA polymerase III subunit theta | - |
| M0538_RS28140 (105980) | 105980..106171 | - | 192 | WP_001568047.1 | hypothetical protein | - |
| M0538_RS28145 (106214) | 106214..106720 | - | 507 | WP_013214014.1 | antirestriction protein ArdA | - |
| M0538_RS28150 (106763) | 106763..107191 | - | 429 | WP_001568045.1 | antirestriction protein | - |
| M0538_RS28155 (107872) | 107872..108639 | - | 768 | WP_013214013.1 | hypothetical protein | - |
| M0538_RS28160 (108693) | 108693..109112 | - | 420 | WP_001568043.1 | DUF1380 domain-containing protein | - |
| M0538_RS28165 (109122) | 109122..109343 | - | 222 | WP_001568042.1 | hypothetical protein | - |
| M0538_RS28170 (109343) | 109343..110044 | - | 702 | WP_001568041.1 | DNA methylase | - |
| M0538_RS28175 (110116) | 110116..110285 | - | 170 | Protein_134 | hypothetical protein | - |
| M0538_RS28180 (110481) | 110481..110711 | - | 231 | WP_001568040.1 | hypothetical protein | - |
| M0538_RS28185 (110774) | 110774..111445 | - | 672 | WP_013214012.1 | plasmid partitioning/stability family protein | - |
| M0538_RS28190 (111448) | 111448..112419 | - | 972 | WP_004152353.1 | plasmid segregation protein ParM | - |
| M0538_RS28195 (112653) | 112653..113084 | + | 432 | WP_001568036.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| M0538_RS28200 (113084) | 113084..114355 | + | 1272 | WP_004197646.1 | Y-family DNA polymerase | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|