MGE detailed information

MGE type: Conjugative plasmid        MGE length: 219384 bp
Accession: NZ_CP095151        Location: 1..219384         Organism: Klebsiella pneumoniae strain Iso00073       Replicon: plasmid pIso00073_01


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MU411_RS26355 1..1011 + 1011 WP_004152063.1 RepB family plasmid replication initiator protein -
MU411_RS26360 1728..2468 - 741 WP_001515717.1 tyrosine-type recombinase/integrase -
MU411_RS26365 3612..4559 + 948 WP_004152065.1 sensor domain-containing diguanylate cyclase -
MU411_RS26370 4586..4897 - 312 WP_071527918.1 EAL domain-containing protein -
MU411_RS26375 4917..5885 + 969 WP_011977741.1 IS5 family transposase IS903B Transposase
MU411_RS26380 6558..6815 - 258 WP_004197688.1 hypothetical protein -
MU411_RS26385 7456..7971 + 516 Protein_6 putative cyclic di-GMP phosphodiesterase PdeB VF
MU411_RS26390 8035..8871 + 837 WP_004178087.1 putative cyclic di-GMP phosphodiesterase PdeB VF
MU411_RS26395 9854..11131 - 1278 WP_004152070.1 DUF2254 domain-containing protein -
MU411_RS26400 11194..13191 - 1998 WP_004178088.1 choline BCCT transporter BetT -
MU411_RS26415 15529..16013 + 485 Protein_12 IS1 family transposase IS1X2 Transposase
MU411_RS26420 16029..16571 + 543 Protein_13 ISL3 family transposase ISKpn25 Transposase
MU411_RS26425 16867..17298 - 432 WP_004178091.1 silver-binding protein SilE -
MU411_RS26430 17549..19024 - 1476 WP_003032875.1 copper/silver sensor histidine kinase SilS -
MU411_RS26435 19017..19697 - 681 WP_001572351.1 Transcriptional regulatory protein CusR VF
MU411_RS26440 19887..21272 + 1386 WP_000475512.1 Cation efflux system protein CusC VF
MU411_RS26445 21301..21654 + 354 WP_001246153.1 cation efflux system protein CusF -
MU411_RS26450 21768..23060 + 1293 WP_004152079.1 Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB -
MU411_RS26455 23071..26217 + 3147 WP_004098958.1 Cu(+)/Ag(+) efflux RND transporter permease subunit SilA -
MU411_RS26460 26304..26744 + 441 WP_000758228.1 DUF411 domain-containing protein -
MU411_RS26465 26871..29318 + 2448 WP_004098955.1 Ag(+)-translocating P-type ATPase SilP -
MU411_RS26470 29359..29556 + 198 WP_000843497.1 DUF2933 domain-containing protein -
MU411_RS26475 29590..30327 - 738 WP_004118669.1 Murein DD-endopeptidase MepM VF
MU411_RS26480 30616..31065 - 450 WP_001023257.1 copper resistance protein -
MU411_RS26485 31299..33116 + 1818 WP_000925242.1 multicopper oxidase PcoA -
MU411_RS26490 33122..34012 + 891 WP_001378118.1 copper resistance outer membrane transporter PcoB -
MU411_RS26495 34052..34432 + 381 WP_000025662.1 copper resistance system metallochaperone PcoC -
MU411_RS26500 34437..35366 + 930 WP_004118344.1 copper resistance inner membrane protein PcoD -
MU411_RS26505 35421..36101 + 681 WP_001188930.1 Transcriptional activator protein CopR VF
MU411_RS26510 36098..37498 + 1401 WP_004152084.1 copper resistance membrane spanning protein PcoS -
MU411_RS26515 37715..38149 + 435 WP_004152085.1 copper resistance system metallochaperone PcoE -
MU411_RS26520 38381..38560 - 180 WP_004152086.1 type II toxin-antitoxin system RelE/ParE family toxin -
MU411_RS26525 38621..40241 - 1621 Protein_34 ISL3 family transposase ISEc38 Transposase
MU411_RS26530 40303..40812 + 510 WP_031944101.1 aquaporin -
MU411_RS26535 40862..41359 - 498 WP_004152091.1 GNAT family N-acetyltransferase -
MU411_RS26540 41691..42017 + 327 WP_004152092.1 metalloregulator ArsR/SmtB family transcription factor -
MU411_RS26545 42014..42727 + 714 WP_004152093.1 arsenical resistance protein ArsH -
MU411_RS26550 42736..43281 + 546 WP_004182005.1 sigma-70 family RNA polymerase sigma factor -
MU411_RS26555 43357..43719 + 363 WP_004152095.1 arsenic metallochaperone ArsD family protein -
MU411_RS26560 43738..45494 + 1757 Protein_41 arsenical pump-driving ATPase -
MU411_RS26565 45616..46152 + 537 WP_004152096.1 GNAT family N-acetyltransferase -
MU411_RS26570 46185..46610 - 426 WP_004152097.1 glutaredoxin-dependent arsenate reductase -
MU411_RS26575 46623..47912 - 1290 WP_004152098.1 arsenite efflux transporter membrane subunit ArsB -
MU411_RS26580 47960..49711 - 1752 WP_004152099.1 Arsenical pump-driving ATPase VF
MU411_RS26585 49729..50091 - 363 WP_004152100.1 arsenite efflux transporter metallochaperone ArsD -
MU411_RS26590 50141..50491 - 351 WP_004152101.1 As(III)-sensing metalloregulatory transcriptional repressor ArsR -
MU411_RS26595 50849..51118 + 270 WP_004152102.1 hypothetical protein -
MU411_RS26600 51106..51681 + 576 WP_004152103.1 hypothetical protein -
MU411_RS26605 51712..52206 + 495 WP_004152104.1 DNA-binding protein -
MU411_RS26610 52250..52618 + 369 WP_004152105.1 hypothetical protein -
MU411_RS26615 52652..52855 + 204 WP_004152106.1 HHA domain-containing protein -
MU411_RS26620 52904..53161 + 258 WP_004152107.1 hypothetical protein -
MU411_RS26625 53237..53491 + 255 WP_004152108.1 hypothetical protein -
MU411_RS26630 53667..53933 + 267 WP_003026799.1 DUF1778 domain-containing protein Antitoxin Detail
MU411_RS26635 53921..54403 + 483 WP_003026803.1 GNAT family N-acetyltransferase Toxin Detail
MU411_RS26640 54615..55961 + 1347 WP_020314316.1 ISNCY family transposase ISLad2 Transposase
MU411_RS28510 56122..56253 + 132 WP_004218042.1 hypothetical protein -
MU411_RS26645 56462..57627 - 1166 Protein_59 IS3 family transposase ISKpn38 Transposase
MU411_RS26650 57804..58766 - 963 WP_004152113.1 zinc metalloprotease HtpX -
MU411_RS26655 58753..59241 - 489 WP_004152114.1 phosphate-starvation-inducible PsiE family protein -
MU411_RS26660 59356..59502 - 147 Protein_62 diguanylate cyclase -
MU411_RS26665 59740..59937 - 198 WP_004152115.1 hypothetical protein -
MU411_RS26670 59937..62732 - 2796 WP_004152116.1 ATP-dependent Clp protease ATP-binding subunit ClpC VF
MU411_RS26675 62847..63416 - 570 WP_004152117.1 Spore protein SP21 VF
MU411_RS26680 63451..63732 - 282 WP_004152118.1 helix-turn-helix domain-containing protein -
MU411_RS26685 63976..64239 - 264 WP_004118208.1 hypothetical protein -
MU411_RS26690 64254..64517 + 264 WP_004118209.1 transposase -
MU411_RS26695 64462..64578 + 117 Protein_69 transposase domain-containing protein -
MU411_RS26700 64763..65460 + 698 WP_223174644.1 IS1 family transposase IS1X2 Transposase
MU411_RS26705 65719..66699 + 981 WP_000019473.1 IS5 family transposase ISKpn26 Transposase
MU411_RS26710 66962..67722 + 761 WP_085947932.1 IS5 family transposase ISKpn12 Transposase
MU411_RS26715 68614..68799 + 186 WP_004197549.1 hypothetical protein -
MU411_RS26720 68865..69347 - 483 Protein_74 IS3 family transposase ISKpn11 Transposase
MU411_RS26725 69416..70924 - 1509 WP_001189111.1 group II intron reverse transcriptase/maturase -
MU411_RS26730 71588..72273 - 686 Protein_76 IS3 family transposase ISKpn11 Transposase
MU411_RS26735 72359..72619 - 261 Protein_77 hypothetical protein -
MU411_RS26740 72632..73492 - 861 WP_000557452.1 SPBc2 prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD ARG
MU411_RS26745 73634..74494 - 861 WP_000027057.1 Beta-lactamase TEM ARG
MU411_RS26750 74677..75234 - 558 WP_001235713.1 Tn3 family transposase TnpR_Tn3 Transposase
MU411_RS26755 75398..75616 + 219 WP_001143771.1 Tn3 family transposase TnpA_Tn3 Transposase
MU411_RS26760 75798..77060 + 1263 WP_000608644.1 IS1380 family transposase ISEcp1 Transposase
MU411_RS26765 77316..78191 + 876 WP_000239590.1 Beta-lactamase CTX-M-1 ARG
MU411_RS26770 78238..78582 - 345 Protein_84 WbuC family cupin fold metalloprotein -
MU411_RS26775 78596..81379 + 2784 Protein_85 Tn3 family transposase TnpA_Tn3 Transposase
MU411_RS26780 81399..81959 - 561 Protein_86 IS6 family transposase IS15DII Transposase
MU411_RS26785 82091..82327 - 237 WP_001087807.1 broad-spectrum mercury transporter MerE -
MU411_RS26790 82324..82689 - 366 WP_001277466.1 mercury resistance co-regulator MerD -
MU411_RS26795 82707..84392 - 1686 WP_000209296.1 mercury(II) reductase -
MU411_RS26800 84431..84856 - 426 WP_000522996.1 organomercurial transporter MerC -
MU411_RS26805 84884..85159 - 276 WP_000732275.1 mercury resistance system periplasmic binding protein MerP -
MU411_RS26810 85175..85555 - 381 WP_031944092.1 mercuric ion transporter MerT -
MU411_RS26815 85627..86082 + 456 WP_001166628.1 IS607 family transposase ISChh1 Transposase
MU411_RS26820 86192..87282 - 1091 Protein_94 IS3 family transposase ISEc36 Transposase
MU411_RS26825 87759..88031 + 273 WP_000333416.1 His-Xaa-Ser system protein HxsD -
MU411_RS26830 88031..89419 + 1389 WP_004118216.1 His-Xaa-Ser system radical SAM maturase HxsB -
MU411_RS26835 89412..90524 + 1113 WP_000005560.1 His-Xaa-Ser system radical SAM maturase HxsC -
MU411_RS26840 90521..91156 + 636 WP_004118217.1 His-Xaa-Ser repeat protein HxsA -
MU411_RS26845 91713..92090 + 378 WP_004114613.1 IS66 family transposase ISSgsp1 Transposase
MU411_RS26850 92087..92434 + 348 WP_004152557.1 IS66 family transposase ISCfr14 Transposase
MU411_RS26855 92484..94021 + 1538 Protein_101 IS66 family transposase ISCfr14 Transposase
MU411_RS26860 94059..94436 + 378 Protein_102 IS66 family transposase ISEc22 Transposase
MU411_RS26865 96257..97990 - 1734 WP_004118832.1 Glutathione import ATP-binding protein GsiA VF
MU411_RS26870 97998..98945 - 948 WP_004118225.1 acetamidase/formamidase family protein -
MU411_RS26875 98990..100594 - 1605 WP_004152278.1 ABC transporter substrate-binding protein -
MU411_RS26880 100607..101527 - 921 WP_004118227.1 ABC transporter permease -
MU411_RS26885 101527..102375 - 849 WP_004152279.1 ABC transporter permease -
MU411_RS26890 102372..102965 - 594 WP_004118229.1 ANTAR domain-containing protein -
MU411_RS26895 102962..104089 - 1128 WP_004118840.1 transporter substrate-binding protein -
MU411_RS26900 104374..104475 - 102 Protein_110 integrase -
MU411_RS26905 104683..105168 + 486 Protein_111 IS21 family transposase ISEc62 Transposase
MU411_RS26910 105438..105507 - 70 Protein_112 hypothetical protein -
MU411_RS26915 105644..106165 + 522 WP_004118235.1 putative RNA polymerase sigma factor FecI VF
MU411_RS26920 106162..107115 + 954 WP_004118237.1 ferric citrate uptake sigma factor regulator FecR -
MU411_RS26925 107201..109525 + 2325 WP_004152280.1 TonB-dependent Fe(3+) dicitrate receptor FecA -
MU411_RS26930 109570..110472 + 903 WP_004118241.1 Fe(3+) dicitrate ABC transporter substrate-binding protein FecB -
MU411_RS26935 110469..111467 + 999 WP_004118243.1 Fe(3+) dicitrate transport system permease protein FecC VF
MU411_RS26940 111464..112420 + 957 WP_245114385.1 Fe(3+) dicitrate transport system permease protein FecD VF
MU411_RS26945 112421..113188 + 768 WP_004152282.1 Fe(3+) dicitrate transport ATP-binding protein FecE VF
MU411_RS26950 113287..113580 + 294 WP_004118251.1 IS66 family transposase ISKpn24 Transposase
MU411_RS26955 113630..113882 + 253 Protein_121 IS66 family transposase -
MU411_RS26960 113911..114108 - 198 WP_072050298.1 EAL domain-containing protein -
MU411_RS26965 114451..115455 - 1005 WP_000427619.1 IS110 family transposase IS5075 Transposase
MU411_RS26970 115859..116869 - 1011 WP_004152284.1 zinc-binding alcohol dehydrogenase family protein -
MU411_RS26975 117212..117294 + 83 Protein_125 hypothetical protein -
MU411_RS26980 117330..118412 + 1083 WP_004152286.1 DNA-binding transcriptional repressor LacI -
MU411_RS26985 118534..121608 + 3075 WP_004152287.1 beta-galactosidase -
MU411_RS26990 121660..122913 + 1254 WP_003846917.1 lactose permease -
MU411_RS26995 123005..123973 + 969 WP_011977764.1 IS5 family transposase IS903B Transposase
MU411_RS27000 124618..126927 + 2310 WP_004152290.1 TerB N-terminal domain-containing protein -
MU411_RS27005 126931..128247 + 1317 WP_004152291.1 ATP-binding protein -
MU411_RS27010 128244..130439 + 2196 WP_000093087.1 DEAD/DEAH box helicase -
MU411_RS27015 131887..132744 - 858 WP_013023768.1 incFII family plasmid replication initiator RepA -
MU411_RS27020 133031..133309 - 279 WP_004099069.1 replication regulatory protein RepA -
MU411_RS27025 133629..134180 - 552 WP_013213996.1 Phospholipase D VF
MU411_RS27030 134285..134364 - 80 Protein_136 hypothetical protein -
MU411_RS27035 134466..134667 - 202 Protein_137 bacteriocin immunity protein -
MU411_RS27040 134780..136318 - 1539 WP_031944116.1 IS66 family transposase ISKpn24 Transposase
MU411_RS27045 136367..136714 - 348 WP_000612626.1 IS66 family transposase ISKpn24 Transposase
MU411_RS27050 136711..137115 - 405 WP_003031976.1 IS66 family transposase ISKpn24 Transposase
MU411_RS27055 137193..137348 + 156 Protein_141 IS3 family transposase ISEc14 Transposase
MU411_RS27060 137569..143304 - 5736 WP_021314612.1 DUF4011 domain-containing protein -
MU411_RS27065 143491..145533 - 2043 WP_013214046.1 DUF262 domain-containing protein -
MU411_RS27070 145526..146977 - 1452 WP_000443938.1 DUF262 domain-containing protein -
MU411_RS27075 147002..147310 - 309 Protein_145 integrase core domain-containing protein -
MU411_RS27080 147327..147566 - 240 Protein_146 IS110 family transposase -
MU411_RS27085 147565..147750 - 186 Protein_147 IS1 family transposase IS1A Transposase
MU411_RS27090 147837..148592 - 756 WP_009310009.1 SprT family zinc-dependent metalloprotease -
MU411_RS27095 148589..151873 - 3285 WP_013214044.1 type I restriction endonuclease subunit R -
MU411_RS27100 151926..152609 - 684 WP_001459731.1 YecA family protein -
MU411_RS27105 152606..153880 - 1275 WP_031944114.1 restriction endonuclease subunit S -
MU411_RS27110 153870..155393 - 1524 WP_013214042.1 type I restriction-modification system subunit M -
MU411_RS27115 155697..156394 - 698 Protein_153 IS1 family transposase -
MU411_RS27120 156526..157128 - 603 WP_015060010.1 PIN domain-containing protein -
MU411_RS27125 157289..157882 - 594 WP_023280883.1 fertility inhibition protein FinO -
MU411_RS27130 158039..158764 - 726 WP_031944112.1 type-F conjugative transfer system pilin acetylase TraX -
MU411_RS27135 158808..164069 - 5262 WP_031944111.1 Multifunctional conjugation protein TraI Relaxase
MU411_RS27140 164069..166381 - 2313 WP_031944110.1 type IV conjugative transfer system coupling protein TraD -
MU411_RS27145 166741..167472 - 732 WP_004152629.1 conjugal transfer complement resistance protein TraT -
MU411_RS27150 167662..168189 - 528 WP_004153030.1 hypothetical protein -
MU411_RS27155 168195..171044 - 2850 WP_004178054.1 conjugal transfer mating-pair stabilization protein TraG -
MU411_RS27160 171044..172414 - 1371 WP_004178055.1 conjugal transfer pilus assembly protein TraH -
MU411_RS27165 172401..172829 - 429 WP_004152689.1 hypothetical protein -
MU411_RS27170 172822..173394 - 573 WP_004152688.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
MU411_RS27175 173366..173605 - 240 WP_004152687.1 type-F conjugative transfer system pilin chaperone TraQ -
MU411_RS27180 173616..174368 - 753 WP_004152686.1 type-F conjugative transfer system pilin assembly protein TraF -
MU411_RS27185 174389..174715 - 327 WP_004152685.1 hypothetical protein -
MU411_RS27190 174943..175179 - 237 WP_004152683.1 conjugal transfer protein TrbE -
MU411_RS27195 175211..177166 - 1956 WP_004153093.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
MU411_RS27200 177214..177852 - 639 WP_004152682.1 type-F conjugative transfer system pilin assembly protein TrbC -
MU411_RS27205 177865..178824 - 960 WP_015065634.1 conjugal transfer pilus assembly protein TraU -
MU411_RS27210 178868..179494 - 627 WP_004152590.1 type-F conjugative transfer system protein TraW -
MU411_RS27215 179494..179883 - 390 WP_004152591.1 type-F conjugative transfer system protein TrbI -
MU411_RS27220 179883..182522 - 2640 WP_004152592.1 type IV secretion system protein TraC -
MU411_RS27225 182594..182992 - 399 WP_004153071.1 hypothetical protein -
MU411_RS27230 183288..183692 - 405 WP_031944109.1 hypothetical protein -
MU411_RS27235 183759..184076 - 318 WP_115830989.1 hypothetical protein -
MU411_RS27240 184077..184295 - 219 WP_004171484.1 hypothetical protein -
MU411_RS27245 184319..184609 - 291 WP_004152596.1 hypothetical protein -
MU411_RS27250 184614..185024 - 411 WP_004152597.1 lipase chaperone -
MU411_RS27255 185156..185725 - 570 WP_004152598.1 type IV conjugative transfer system lipoprotein TraV -
MU411_RS27260 185748..186344 - 597 WP_004152599.1 conjugal transfer pilus-stabilizing protein TraP -
MU411_RS27265 186337..187761 - 1425 WP_004152600.1 F-type conjugal transfer pilus assembly protein TraB -
MU411_RS27270 187761..188501 - 741 WP_004152601.1 type-F conjugative transfer system secretin TraK -
MU411_RS27275 188488..189054 - 567 WP_004152602.1 type IV conjugative transfer system protein TraE -
MU411_RS27280 189074..189379 - 306 WP_004178059.1 type IV conjugative transfer system protein TraL -
MU411_RS27285 189393..189761 - 369 WP_004178060.1 type IV conjugative transfer system pilin TraA -
MU411_RS27290 189815..190186 - 372 WP_004208838.1 TraY domain-containing protein -
MU411_RS27295 190270..190965 - 696 WP_004178061.1 transcriptional regulator TraJ family protein -
MU411_RS27300 191179..191571 - 393 WP_004178062.1 conjugal transfer relaxosome DNA-binding protein TraM -
MU411_RS27305 192005..192490 + 486 WP_004178063.1 hypothetical protein VF
MU411_RS27310 192523..192852 - 330 WP_011977736.1 DUF5983 family protein -
MU411_RS27315 192885..193706 - 822 WP_004178064.1 DUF932 domain-containing protein -
MU411_RS27320 194540..194953 - 414 WP_004152722.1 helix-turn-helix domain-containing protein -
MU411_RS27325 194954..195232 - 279 WP_004152721.1 helix-turn-helix transcriptional regulator -
MU411_RS27330 195222..195542 - 321 WP_004152720.1 type II toxin-antitoxin system RelE/ParE family toxin -
MU411_RS27335 195623..195847 - 225 WP_004152719.1 hypothetical protein -
MU411_RS27340 195858..196070 - 213 WP_004152718.1 hypothetical protein -
MU411_RS27345 196131..196487 - 357 WP_004152717.1 hypothetical protein -
MU411_RS27350 197123..197473 - 351 WP_004152758.1 hypothetical protein -
MU411_RS27355 197470..197742 - 273 WP_004152759.1 hypothetical protein -
MU411_RS27360 198442..198564 - 123 WP_085842394.1 Hok/Gef family protein -
MU411_RS27365 198509..198661 - 153 Protein_203 DUF5431 family protein -
MU411_RS27370 198831..199205 - 375 WP_004152638.1 hypothetical protein -
MU411_RS27375 199261..199587 - 327 WP_004152639.1 hypothetical protein -
MU411_RS27380 199584..200312 - 729 WP_004152640.1 plasmid SOS inhibition protein A -
MU411_RS27385 200309..200740 - 432 WP_004152641.1 conjugation system SOS inhibitor PsiB -
MU411_RS27390 200785..202843 - 2059 Protein_208 ParB/RepB/Spo0J family partition protein -
MU411_RS27395 202913..203161 - 249 WP_004152643.1 DUF905 domain-containing protein -
MU411_RS27400 203210..203752 - 543 WP_004152644.1 single-stranded DNA-binding protein -
MU411_RS27405 204528..205091 - 564 WP_004152645.1 methyltransferase -
MU411_RS27410 205139..206494 - 1356 WP_004178068.1 DUF3560 domain-containing protein -
MU411_RS27415 206546..206776 - 231 WP_004198570.1 hypothetical protein -
MU411_RS27420 206868..207095 - 228 WP_004178072.1 hypothetical protein -
MU411_RS27425 207877..208194 - 318 WP_004118473.1 hypothetical protein -
MU411_RS27430 208229..208483 - 255 WP_004152754.1 DNA polymerase III subunit theta -
MU411_RS27435 208720..209145 - 426 WP_004118478.1 antirestriction protein -
MU411_RS27440 209666..209896 - 231 WP_004152753.1 hypothetical protein -
MU411_RS27445 210130..211617 - 1488 WP_004178082.1 group II intron reverse transcriptase/maturase -
MU411_RS27450 212020..212445 + 426 WP_004178083.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
MU411_RS27455 212445..213716 + 1272 WP_004152715.1 Y-family DNA polymerase -
MU411_RS27460 213855..214010 + 156 WP_001776126.1 hypothetical protein -
MU411_RS27465 214033..215231 - 1199 Protein_223 IS200-IS605 family transposase IS609 Transposase
MU411_RS27470 216496..217467 - 972 WP_004152062.1 ParB/RepB/Spo0J family plasmid partition protein -
MU411_RS27475 217467..218633 - 1167 WP_000523813.1 Sporulation initiation inhibitor protein Soj VF

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance