MGE detailed information

MGE type: Conjugative plasmid        MGE length: 221581 bp
Accession: NZ_CP095141        Location: 1..221581         Organism: Klebsiella pneumoniae strain Iso00199       Replicon: plasmid pIso00199_01


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MU413_RS26445 1..1011 + 1011 WP_004152063.1 RepB family plasmid replication initiator protein -
MU413_RS26450 1728..2468 - 741 WP_001515717.1 tyrosine-type recombinase/integrase -
MU413_RS26455 3612..4559 + 948 WP_004152065.1 sensor domain-containing diguanylate cyclase -
MU413_RS26460 4586..4897 - 312 WP_071527918.1 EAL domain-containing protein -
MU413_RS26465 4917..5885 + 969 WP_011977741.1 IS5 family transposase IS903B Transposase
MU413_RS26470 6558..6815 - 258 WP_004197688.1 hypothetical protein -
MU413_RS26475 7456..7971 + 516 Protein_6 hypothetical protein VF
MU413_RS26480 8035..8871 + 837 WP_004178087.1 hypothetical protein VF
MU413_RS26485 9854..11131 - 1278 WP_004152070.1 DUF2254 domain-containing protein -
MU413_RS26490 11194..13191 - 1998 WP_004178088.1 choline BCCT transporter BetT -
MU413_RS26505 15529..16013 + 485 Protein_12 IS1 family transposase IS1X2 Transposase
MU413_RS26510 16029..16571 + 543 Protein_13 ISL3 family transposase ISKpn25 Transposase
MU413_RS26515 16867..17298 - 432 WP_004178091.1 silver-binding protein SilE -
MU413_RS26520 17549..19024 - 1476 WP_003032875.1 copper/silver sensor histidine kinase SilS -
MU413_RS26525 19017..19697 - 681 WP_001572351.1 Regulator of RpoS VF
MU413_RS26530 19887..21272 + 1386 WP_000475512.1 hypothetical protein VF
MU413_RS26535 21301..21654 + 354 WP_001246153.1 cation efflux system protein CusF -
MU413_RS26540 21768..23060 + 1293 WP_004152079.1 Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB -
MU413_RS26545 23071..26217 + 3147 WP_004098958.1 Cu(+)/Ag(+) efflux RND transporter permease subunit SilA -
MU413_RS26550 26304..26744 + 441 WP_000758228.1 DUF411 domain-containing protein -
MU413_RS26555 26871..29318 + 2448 WP_004098955.1 Ag(+)-translocating P-type ATPase SilP -
MU413_RS26560 29359..29556 + 198 WP_000843497.1 DUF2933 domain-containing protein -
MU413_RS26565 29590..30327 - 738 WP_004118669.1 hypothetical protein VF
MU413_RS26570 30616..31065 - 450 WP_001023257.1 copper resistance protein -
MU413_RS26575 31299..33116 + 1818 WP_000925242.1 multicopper oxidase PcoA -
MU413_RS26580 33122..34012 + 891 WP_001378118.1 copper resistance outer membrane transporter PcoB -
MU413_RS26585 34052..34432 + 381 WP_000025662.1 copper resistance system metallochaperone PcoC -
MU413_RS26590 34437..35366 + 930 WP_004118344.1 copper resistance inner membrane protein PcoD -
MU413_RS26595 35421..36101 + 681 WP_001188930.1 Regulator of RpoS VF
MU413_RS26600 36098..37498 + 1401 WP_004152084.1 copper resistance membrane spanning protein PcoS -
MU413_RS26605 37715..38149 + 435 WP_004152085.1 copper resistance system metallochaperone PcoE -
MU413_RS26610 38381..38560 - 180 WP_004152086.1 type II toxin-antitoxin system RelE/ParE family toxin -
MU413_RS26615 38621..40241 - 1621 Protein_34 ISL3 family transposase ISEc38 Transposase
MU413_RS26620 40303..40812 + 510 WP_031944101.1 aquaporin -
MU413_RS26625 40862..41359 - 498 WP_004152091.1 GNAT family N-acetyltransferase -
MU413_RS26630 41691..42017 + 327 WP_004152092.1 metalloregulator ArsR/SmtB family transcription factor -
MU413_RS26635 42014..42727 + 714 WP_004152093.1 arsenical resistance protein ArsH -
MU413_RS26640 42736..43281 + 546 WP_004182005.1 sigma-70 family RNA polymerase sigma factor -
MU413_RS26645 43357..43719 + 363 WP_004152095.1 arsenic metallochaperone ArsD family protein -
MU413_RS26650 43738..45494 + 1757 Protein_41 arsenical pump-driving ATPase -
MU413_RS26655 45616..46152 + 537 WP_004152096.1 GNAT family N-acetyltransferase -
MU413_RS26660 46185..46610 - 426 WP_004152097.1 glutaredoxin-dependent arsenate reductase -
MU413_RS26665 46623..47912 - 1290 WP_004152098.1 arsenite efflux transporter membrane subunit ArsB -
MU413_RS26670 47960..49711 - 1752 WP_004152099.1 Iron-sulfur cluster carrier protein VF
MU413_RS26675 49729..50091 - 363 WP_004152100.1 arsenite efflux transporter metallochaperone ArsD -
MU413_RS26680 50141..50491 - 351 WP_004152101.1 As(III)-sensing metalloregulatory transcriptional repressor ArsR -
MU413_RS26685 50849..51118 + 270 WP_004152102.1 hypothetical protein -
MU413_RS26690 51106..51681 + 576 WP_004152103.1 hypothetical protein -
MU413_RS26695 51712..52206 + 495 WP_004152104.1 DNA-binding protein -
MU413_RS26700 52250..52618 + 369 WP_004152105.1 hypothetical protein -
MU413_RS26705 52652..52855 + 204 WP_004152106.1 HHA domain-containing protein -
MU413_RS26710 52904..53161 + 258 WP_004152107.1 hypothetical protein -
MU413_RS26715 53237..53491 + 255 WP_004152108.1 hypothetical protein -
MU413_RS26720 53667..53933 + 267 WP_003026799.1 DUF1778 domain-containing protein Antitoxin Detail
MU413_RS26725 53921..54403 + 483 WP_003026803.1 GNAT family N-acetyltransferase Toxin Detail
MU413_RS26730 54615..55961 + 1347 WP_020314316.1 ISNCY family transposase ISLad2 Transposase
MU413_RS28020 56122..56253 + 132 WP_004218042.1 hypothetical protein -
MU413_RS26735 56462..57627 - 1166 Protein_59 IS3 family transposase ISKpn38 Transposase
MU413_RS26740 57804..58766 - 963 WP_004152113.1 zinc metalloprotease HtpX -
MU413_RS26745 58753..59241 - 489 WP_004152114.1 phosphate-starvation-inducible PsiE family protein -
MU413_RS26750 59356..59502 - 147 Protein_62 diguanylate cyclase -
MU413_RS26755 59740..59937 - 198 WP_004152115.1 hypothetical protein -
MU413_RS26760 59937..62732 - 2796 WP_004152116.1 ATP-dependent Clp protease ATP-binding subunit ClpX VF
MU413_RS26765 62847..63416 - 570 WP_004152117.1 Small heat shock protein IbpA VF
MU413_RS26770 63451..63732 - 282 WP_004152118.1 helix-turn-helix domain-containing protein -
MU413_RS26775 63976..64239 - 264 WP_004118208.1 hypothetical protein -
MU413_RS26780 64254..64517 + 264 WP_004118209.1 transposase -
MU413_RS26785 64462..64578 + 117 Protein_69 transposase domain-containing protein -
MU413_RS26790 64763..65460 + 698 WP_223174644.1 IS1 family transposase IS1X2 Transposase
MU413_RS26795 65719..66699 + 981 WP_000019473.1 IS5 family transposase ISKpn26 Transposase
MU413_RS26800 66957..67717 + 761 WP_085947932.1 IS5 family transposase ISKpn12 Transposase
MU413_RS26805 68609..68794 + 186 WP_004197549.1 hypothetical protein -
MU413_RS26810 68860..69342 - 483 Protein_74 IS3 family transposase ISKpn11 Transposase
MU413_RS26815 69411..70919 - 1509 WP_001189111.1 group II intron reverse transcriptase/maturase -
MU413_RS26820 71583..72268 - 686 Protein_76 IS3 family transposase ISKpn11 Transposase
MU413_RS26825 72354..72614 - 261 Protein_77 hypothetical protein -
MU413_RS26830 72627..73487 - 861 WP_000557452.1 hypothetical protein ARG
MU413_RS26835 73629..74489 - 861 WP_000027057.1 hypothetical protein ARG
MU413_RS26840 74672..75229 - 558 WP_001235713.1 Tn3 family transposase TnpR_Tn3 Transposase
MU413_RS26845 75393..75611 + 219 WP_001143771.1 Tn3 family transposase TnpA_Tn3 Transposase
MU413_RS26850 75793..77055 + 1263 WP_000608644.1 IS1380 family transposase ISEcp1 Transposase
MU413_RS26855 77311..78186 + 876 WP_000239590.1 hypothetical protein ARG
MU413_RS26860 78233..78577 - 345 Protein_84 WbuC family cupin fold metalloprotein -
MU413_RS26865 78591..81374 + 2784 Protein_85 Tn3 family transposase TnpA_Tn3 Transposase
MU413_RS26870 81394..81954 - 561 Protein_86 IS6 family transposase IS15DII Transposase
MU413_RS26875 82086..82322 - 237 WP_001087807.1 broad-spectrum mercury transporter MerE -
MU413_RS26880 82319..82684 - 366 WP_001277466.1 mercury resistance co-regulator MerD -
MU413_RS26885 82702..84387 - 1686 WP_000209296.1 mercury(II) reductase -
MU413_RS26890 84426..84851 - 426 WP_000522996.1 organomercurial transporter MerC -
MU413_RS26895 84879..85154 - 276 WP_000732275.1 mercury resistance system periplasmic binding protein MerP -
MU413_RS26900 85170..85550 - 381 WP_001294654.1 mercuric ion transporter MerT -
MU413_RS26905 85622..86077 + 456 WP_001166628.1 IS607 family transposase ISChh1 Transposase
MU413_RS26910 86187..87277 - 1091 Protein_94 IS3 family transposase ISEc36 Transposase
MU413_RS26915 87754..88026 + 273 WP_000333416.1 His-Xaa-Ser system protein HxsD -
MU413_RS26920 88026..89414 + 1389 WP_004118216.1 His-Xaa-Ser system radical SAM maturase HxsB -
MU413_RS26925 89407..90519 + 1113 WP_000005560.1 His-Xaa-Ser system radical SAM maturase HxsC -
MU413_RS26930 90516..91151 + 636 WP_004118217.1 His-Xaa-Ser repeat protein HxsA -
MU413_RS26935 91708..92085 + 378 WP_004114613.1 IS66 family transposase ISSgsp1 Transposase
MU413_RS26940 92082..92429 + 348 WP_004152557.1 IS66 family transposase ISCfr14 Transposase
MU413_RS26945 92479..94016 + 1538 Protein_101 IS66 family transposase ISCfr14 Transposase
MU413_RS26950 94054..94431 + 378 Protein_102 IS66 family transposase ISEc22 Transposase
MU413_RS26955 96252..97985 - 1734 WP_004118832.1 Vitamin B12 import ATP-binding protein BtuD VF
MU413_RS26960 97993..98940 - 948 WP_004118225.1 acetamidase/formamidase family protein -
MU413_RS26965 98985..100589 - 1605 WP_004152278.1 ABC transporter substrate-binding protein -
MU413_RS26970 100602..101522 - 921 WP_004118227.1 ABC transporter permease -
MU413_RS26975 101522..102370 - 849 WP_004152279.1 ABC transporter permease -
MU413_RS26980 102367..102960 - 594 WP_004118229.1 ANTAR domain-containing protein -
MU413_RS26985 102957..104084 - 1128 WP_004118840.1 transporter substrate-binding protein -
MU413_RS26990 104369..104470 - 102 Protein_110 integrase -
MU413_RS26995 104465..104677 + 213 WP_161989521.1 hypothetical protein -
MU413_RS27000 104678..105163 + 486 Protein_112 IS21 family transposase ISEc62 Transposase
MU413_RS27005 105433..105502 - 70 Protein_113 hypothetical protein -
MU413_RS27010 105639..106160 + 522 WP_004118235.1 hypothetical protein VF
MU413_RS27015 106157..107110 + 954 WP_004118237.1 ferric citrate uptake sigma factor regulator FecR -
MU413_RS27020 107196..109520 + 2325 WP_004152280.1 TonB-dependent Fe(3+) dicitrate receptor FecA -
MU413_RS27025 109565..110467 + 903 WP_004118241.1 Fe(3+) dicitrate ABC transporter substrate-binding protein FecB -
MU413_RS27030 110464..111462 + 999 WP_004118243.1 Vitamin B12 import system permease protein BtuC VF
MU413_RS27035 111459..112415 + 957 WP_004152281.1 Vitamin B12 import system permease protein BtuC VF
MU413_RS27040 112416..113183 + 768 WP_004152282.1 Vitamin B12 import ATP-binding protein BtuD VF
MU413_RS27045 113282..113575 + 294 WP_004118251.1 IS66 family transposase ISKpn24 Transposase
MU413_RS27050 113625..113877 + 253 Protein_122 IS66 family transposase -
MU413_RS27055 113906..114103 - 198 WP_072050298.1 EAL domain-containing protein -
MU413_RS27060 114446..115450 - 1005 WP_000427619.1 IS110 family transposase IS5075 Transposase
MU413_RS27065 115854..116864 - 1011 WP_004152284.1 zinc-binding alcohol dehydrogenase family protein -
MU413_RS27070 117207..117289 + 83 Protein_126 hypothetical protein -
MU413_RS27075 117325..118407 + 1083 WP_004152286.1 DNA-binding transcriptional repressor LacI -
MU413_RS27080 118529..121603 + 3075 WP_004152287.1 beta-galactosidase -
MU413_RS27085 121655..122908 + 1254 WP_003846917.1 lactose permease -
MU413_RS27090 123000..123968 + 969 WP_011977764.1 IS5 family transposase IS903B Transposase
MU413_RS27095 124613..126922 + 2310 WP_004152290.1 TerB N-terminal domain-containing protein -
MU413_RS27100 126926..128242 + 1317 WP_004152291.1 ATP-binding protein -
MU413_RS27105 128239..130434 + 2196 WP_000093087.1 DEAD/DEAH box helicase -
MU413_RS27110 131882..132739 - 858 WP_013023768.1 incFII family plasmid replication initiator RepA -
MU413_RS27115 133026..133304 - 279 WP_004099069.1 replication regulatory protein RepA -
MU413_RS27120 133624..134175 - 552 WP_013213996.1 Cardiolipin synthase B VF
MU413_RS27125 134280..134359 - 80 Protein_137 hypothetical protein -
MU413_RS27130 134461..134662 - 202 Protein_138 bacteriocin immunity protein -
MU413_RS27135 134775..136313 - 1539 WP_097404981.1 IS66 family transposase ISKpn24 Transposase
MU413_RS27140 136362..136709 - 348 WP_000612626.1 IS66 family transposase ISKpn24 Transposase
MU413_RS27145 136706..137110 - 405 WP_003031976.1 IS66 family transposase ISKpn24 Transposase
MU413_RS27150 137188..137343 + 156 Protein_142 IS3 family transposase ISEc14 Transposase
MU413_RS27155 137564..143299 - 5736 WP_021314612.1 DUF4011 domain-containing protein -
MU413_RS27160 143486..145528 - 2043 WP_013214046.1 DUF262 domain-containing protein -
MU413_RS27165 145521..146972 - 1452 WP_000443938.1 DUF262 domain-containing protein -
MU413_RS27170 146997..147305 - 309 Protein_146 integrase core domain-containing protein -
MU413_RS27175 147322..147561 - 240 Protein_147 IS110 family transposase -
MU413_RS27180 147560..147745 - 186 Protein_148 IS1-like element transposase -
MU413_RS27185 147832..148587 - 756 WP_009310009.1 SprT family zinc-dependent metalloprotease -
MU413_RS27190 148584..151868 - 3285 WP_013214044.1 type I restriction endonuclease subunit R -
MU413_RS27195 151921..152604 - 684 WP_001459731.1 YecA family protein -
MU413_RS27200 152601..153875 - 1275 WP_031944114.1 restriction endonuclease subunit S -
MU413_RS27205 153865..155388 - 1524 WP_013214042.1 type I restriction-modification system subunit M -
MU413_RS27210 155692..156389 - 698 Protein_154 IS1 family transposase -
MU413_RS27215 156521..157123 - 603 WP_015060010.1 PIN domain-containing protein -
MU413_RS27220 157284..157877 - 594 WP_023280883.1 fertility inhibition protein FinO -
MU413_RS27225 158034..158759 - 726 WP_031944112.1 type-F conjugative transfer system pilin acetylase TraX -
MU413_RS27230 158803..164064 - 5262 WP_031944111.1 Multifunctional conjugation protein TraI Relaxase
MU413_RS27235 164064..166376 - 2313 WP_031944110.1 type IV conjugative transfer system coupling protein TraD -
MU413_RS27240 166736..167467 - 732 WP_004152629.1 conjugal transfer complement resistance protein TraT -
MU413_RS27245 167657..168184 - 528 WP_004153030.1 hypothetical protein -
MU413_RS27250 168190..171039 - 2850 WP_004178054.1 conjugal transfer mating-pair stabilization protein TraG -
MU413_RS27255 171039..172409 - 1371 WP_004178055.1 conjugal transfer pilus assembly protein TraH -
MU413_RS27260 172396..172824 - 429 WP_004152689.1 hypothetical protein -
MU413_RS27265 172817..173389 - 573 WP_004152688.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
MU413_RS27270 173361..173600 - 240 WP_004152687.1 type-F conjugative transfer system pilin chaperone TraQ -
MU413_RS27275 173611..174363 - 753 WP_004152686.1 type-F conjugative transfer system pilin assembly protein TraF -
MU413_RS27280 174384..174710 - 327 WP_004152685.1 hypothetical protein -
MU413_RS27285 174938..175174 - 237 WP_004152683.1 conjugal transfer protein TrbE -
MU413_RS27290 175206..177161 - 1956 WP_004153093.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
MU413_RS27295 177209..177847 - 639 WP_004152682.1 type-F conjugative transfer system pilin assembly protein TrbC -
MU413_RS27300 177860..178819 - 960 WP_015065634.1 conjugal transfer pilus assembly protein TraU -
MU413_RS27305 178863..179489 - 627 WP_004152590.1 type-F conjugative transfer system protein TraW -
MU413_RS27310 179489..179878 - 390 WP_004152591.1 type-F conjugative transfer system protein TrbI -
MU413_RS27315 179878..182517 - 2640 WP_004152592.1 type IV secretion system protein TraC -
MU413_RS27320 182589..182987 - 399 WP_004153071.1 hypothetical protein -
MU413_RS27325 183283..183687 - 405 WP_031944109.1 hypothetical protein -
MU413_RS27330 183754..184071 - 318 WP_004152595.1 hypothetical protein -
MU413_RS27335 184072..184290 - 219 WP_004171484.1 hypothetical protein -
MU413_RS27340 184314..184604 - 291 WP_004152596.1 hypothetical protein -
MU413_RS27345 184609..185019 - 411 WP_004152597.1 lipase chaperone -
MU413_RS27350 185151..185720 - 570 WP_004152598.1 type IV conjugative transfer system lipoprotein TraV -
MU413_RS27355 185743..186339 - 597 WP_004152599.1 conjugal transfer pilus-stabilizing protein TraP -
MU413_RS27360 186332..187756 - 1425 WP_004152600.1 F-type conjugal transfer pilus assembly protein TraB -
MU413_RS27365 187756..188496 - 741 WP_004152601.1 type-F conjugative transfer system secretin TraK -
MU413_RS27370 188483..189049 - 567 WP_004152602.1 type IV conjugative transfer system protein TraE -
MU413_RS27375 189069..189374 - 306 WP_004178059.1 type IV conjugative transfer system protein TraL -
MU413_RS27380 189388..189756 - 369 WP_004178060.1 type IV conjugative transfer system pilin TraA -
MU413_RS27385 189810..190181 - 372 WP_004208838.1 TraY domain-containing protein -
MU413_RS27390 190265..190960 - 696 WP_004178061.1 transcriptional regulator TraJ family protein -
MU413_RS27395 191174..191566 - 393 WP_004178062.1 conjugal transfer relaxosome DNA-binding protein TraM -
MU413_RS27400 192000..192485 + 486 WP_004178063.1 hypothetical protein VF
MU413_RS27405 192518..192847 - 330 WP_011977736.1 DUF5983 family protein -
MU413_RS27410 192880..193701 - 822 WP_004178064.1 DUF932 domain-containing protein -
MU413_RS27415 194535..194948 - 414 WP_004152722.1 helix-turn-helix domain-containing protein -
MU413_RS27420 194949..195227 - 279 WP_004152721.1 helix-turn-helix transcriptional regulator -
MU413_RS27425 195217..195537 - 321 WP_004152720.1 type II toxin-antitoxin system RelE/ParE family toxin -
MU413_RS27430 195618..195842 - 225 WP_004152719.1 hypothetical protein -
MU413_RS27435 195853..196065 - 213 WP_004152718.1 hypothetical protein -
MU413_RS27440 196126..196482 - 357 WP_004152717.1 hypothetical protein -
MU413_RS27445 197118..197468 - 351 WP_004152758.1 hypothetical protein -
MU413_RS27450 197465..197737 - 273 WP_004152759.1 hypothetical protein -
MU413_RS27455 198437..198598 - 162 WP_004118124.1 type I toxin-antitoxin system Hok family toxin -
MU413_RS27460 198670..199719 + 1050 WP_032448955.1 IS481 family transposase ISKpn28 Transposase
MU413_RS27465 199771..200850 + 1080 WP_004220208.1 IS481 family transposase ISKpn28 Transposase
MU413_RS27470 201028..201402 - 375 WP_004152638.1 hypothetical protein -
MU413_RS27475 201458..201784 - 327 WP_004152639.1 hypothetical protein -
MU413_RS27480 201781..202509 - 729 WP_004152640.1 plasmid SOS inhibition protein A -
MU413_RS27485 202506..202937 - 432 WP_004152641.1 conjugation system SOS inhibitor PsiB -
MU413_RS27490 202982..205040 - 2059 Protein_210 ParB/RepB/Spo0J family partition protein -
MU413_RS27495 205110..205358 - 249 WP_004152643.1 DUF905 domain-containing protein -
MU413_RS27500 205407..205949 - 543 WP_004152644.1 single-stranded DNA-binding protein -
MU413_RS27505 206725..207288 - 564 WP_004152645.1 methyltransferase -
MU413_RS27510 207336..208691 - 1356 WP_004178068.1 DUF3560 domain-containing protein -
MU413_RS27515 208743..208973 - 231 WP_004198570.1 hypothetical protein -
MU413_RS27520 209065..209292 - 228 WP_004178072.1 hypothetical protein -
MU413_RS27525 210074..210391 - 318 WP_004118473.1 hypothetical protein -
MU413_RS27530 210426..210680 - 255 WP_004152754.1 DNA polymerase III subunit theta -
MU413_RS27535 210917..211342 - 426 WP_004118478.1 antirestriction protein -
MU413_RS27540 211863..212093 - 231 WP_004152753.1 hypothetical protein -
MU413_RS27545 212327..213814 - 1488 WP_004178082.1 group II intron reverse transcriptase/maturase -
MU413_RS27550 214217..214642 + 426 WP_004178083.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
MU413_RS27555 214642..215913 + 1272 WP_004152715.1 Y-family DNA polymerase -
MU413_RS27560 216052..216207 + 156 WP_001776126.1 hypothetical protein -
MU413_RS27565 216230..217428 - 1199 Protein_225 IS200-IS605 family transposase IS609 Transposase
MU413_RS27570 218693..219664 - 972 WP_004152062.1 ParB/RepB/Spo0J family plasmid partition protein -
MU413_RS27575 219664..220830 - 1167 WP_000523813.1 Sporulation initiation inhibitor protein Soj VF

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance