MGE detailed information
MGE type: Mobilizable plasmid MGE length: 133775 bp
Accession: NZ_CP092795 Location: 1..133775 Organism: Klebsiella pneumoniae strain XH1507 Replicon: plasmid pXH1507-2
Accession: NZ_CP092795 Location: 1..133775 Organism: Klebsiella pneumoniae strain XH1507 Replicon: plasmid pXH1507-2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ML258_RS28150 (1) | 1..858 | + | 858 | WP_032495102.1 | incFII family plasmid replication initiator RepA | - |
| ML258_RS28155 (1797) | 1797..2450 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| ML258_RS28160 (2543) | 2543..2800 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| ML258_RS28165 (2733) | 2733..3134 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| ML258_RS28170 (3383) | 3383..3798 | + | 416 | Protein_4 | IS1-like element IS1B family transposase | - |
| ML258_RS28175 (3834) | 3834..4379 | - | 546 | Protein_5 | Tn3 family transposase TnpA_Tn3 | Transposase |
| ML258_RS28180 (4445) | 4445..5149 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| ML258_RS28185 (5219) | 5219..5410 | + | 192 | Protein_7 | IS1380 family transposase | - |
| ML258_RS28190 (5660) | 5660..6535 | + | 876 | WP_013188475.1 | Beta-lactamase Toho-1 | ARG |
| ML258_RS28195 (6570) | 6570..7538 | + | 969 | WP_013362812.1 | IS5 family transposase IS903B | Transposase |
| ML258_RS28200 (7595) | 7595..8692 | + | 1098 | Protein_10 | TonB-dependent receptor | - |
| ML258_RS28205 (8760) | 8760..9236 | - | 477 | Protein_11 | PAS domain-containing protein | - |
| ML258_RS28210 (9289) | 9289..9993 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| ML258_RS28215 (10058) | 10058..10648 | + | 591 | Protein_13 | IS91 family transposase ISSbo1 | Transposase |
| ML258_RS28220 (11104) | 11104..11808 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| ML258_RS28225 (11859) | 11859..12476 | - | 618 | Protein_15 | IS91 family transposase ISSbo1 | Transposase |
| ML258_RS28230 (12486) | 12486..12674 | - | 189 | WP_000957857.1 | hypothetical protein | - |
| ML258_RS28235 (12766) | 12766..13302 | + | 537 | WP_064441864.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| ML258_RS28240 (13485) | 13485..14345 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| ML258_RS28245 (14515) | 14515..15270 | + | 756 | WP_012372818.1 | 16S rRNA (guanine(1405)-N(7))-methyltransferase | ARG |
| ML258_RS28250 (15351) | 15351..15665 | - | 315 | Protein_20 | hypothetical protein | - |
| ML258_RS28255 (15720) | 15720..16424 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| ML258_RS28260 (16490) | 16490..16555 | + | 66 | Protein_22 | IS1 family transposase | - |
| ML258_RS28265 (18004) | 18004..18238 | + | 235 | Protein_23 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| ML258_RS28270 (18366) | 18366..18647 | + | 282 | WP_001333089.1 | hypothetical protein | - |
| ML258_RS28275 (18770) | 18770..19120 | - | 351 | WP_000361389.1 | plasmid partitioning/stability family protein | - |
| ML258_RS28280 (19123) | 19123..20085 | - | 963 | WP_000959884.1 | plasmid segregation protein ParM | - |
| ML258_RS28285 (20232) | 20232..20525 | + | 294 | WP_032146011.1 | hypothetical protein | - |
| ML258_RS28290 (20602) | 20602..21285 | + | 684 | WP_000085883.1 | DNA methylase | - |
| ML258_RS28295 (21286) | 21286..21507 | + | 222 | WP_001104881.1 | hypothetical protein | - |
| ML258_RS28300 (21521) | 21521..21955 | + | 435 | WP_000274503.1 | DUF1380 family protein | - |
| ML258_RS28305 (22006) | 22006..22782 | + | 777 | WP_001383963.1 | hypothetical protein | - |
| ML258_RS28310 (23200) | 23200..23625 | + | 426 | WP_001198928.1 | antirestriction protein | - |
| ML258_RS28315 (23672) | 23672..24094 | + | 423 | WP_000271762.1 | DUF1380 family protein | - |
| ML258_RS28320 (24091) | 24091..24282 | + | 192 | WP_001027493.1 | hypothetical protein | - |
| ML258_RS28325 (24596) | 24596..26263 | - | 1668 | WP_012372796.1 | group II intron reverse transcriptase/maturase | - |
| ML258_RS28330 (26992) | 26992..27146 | - | 155 | Protein_36 | hypothetical protein | - |
| ML258_RS28335 (27663) | 27663..27893 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| ML258_RS28340 (27945) | 27945..29306 | + | 1362 | WP_000170695.1 | DUF3560 domain-containing protein | - |
| ML258_RS28345 (29353) | 29353..29916 | + | 564 | WP_015059007.1 | class I SAM-dependent methyltransferase | - |
| ML258_RS28350 (30002) | 30002..30457 | - | 456 | Protein_40 | hypothetical protein | - |
| ML258_RS28355 (30759) | 30759..31286 | + | 528 | WP_000290834.1 | single-stranded DNA-binding protein | - |
| ML258_RS28360 (31344) | 31344..31577 | + | 234 | WP_000006003.1 | DUF905 family protein | - |
| ML258_RS28365 (31638) | 31638..33661 | + | 2024 | Protein_43 | ParB/RepB/Spo0J family partition protein | - |
| ML258_RS28370 (33730) | 33730..34164 | + | 435 | WP_000845953.1 | conjugation system SOS inhibitor PsiB | - |
| ML258_RS28375 (34161) | 34161..34880 | + | 720 | WP_001276217.1 | plasmid SOS inhibition protein A | - |
| - (34892) | 34892..35116 | + | 225 | NuclAT_0 | - | - |
| - (34892) | 34892..35116 | + | 225 | NuclAT_0 | - | - |
| - (34892) | 34892..35116 | + | 225 | NuclAT_0 | - | - |
| - (34892) | 34892..35116 | + | 225 | NuclAT_0 | - | - |
| ML258_RS28380 (35102) | 35102..35251 | + | 150 | Protein_46 | plasmid maintenance protein Mok | - |
| ML258_RS28385 (35193) | 35193..35318 | + | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| ML258_RS28390 (35637) | 35637..35933 | - | 297 | Protein_48 | hypothetical protein | - |
| ML258_RS28395 (36233) | 36233..36529 | + | 297 | WP_001272251.1 | hypothetical protein | - |
| ML258_RS28400 (36640) | 36640..37461 | + | 822 | WP_001234445.1 | DUF932 domain-containing protein | - |
| ML258_RS28405 (37758) | 37758..38405 | - | 648 | WP_015059008.1 | hypothetical protein | VF |
| ML258_RS28410 (38682) | 38682..39065 | + | 384 | WP_000124981.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| ML258_RS28415 (39346) | 39346..40050 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| ML258_RS28420 (40104) | 40104..40427 | - | 324 | Protein_54 | class II aldolase/adducin family protein | - |
| ML258_RS28425 (40420) | 40420..41672 | - | 1253 | Protein_55 | four-carbon acid sugar kinase family protein | - |
| ML258_RS28430 (41684) | 41684..42586 | - | 903 | WP_002903955.1 | NAD(P)-dependent oxidoreductase | - |
| ML258_RS28435 (42848) | 42848..43609 | + | 762 | WP_002210513.1 | DeoR/GlpR family DNA-binding transcription regulator | - |
| ML258_RS28440 (43630) | 43630..44490 | - | 861 | WP_002904004.1 | Beta-lactamase SHV-2 | ARG |
| ML258_RS28445 (44627) | 44627..44695 | + | 69 | Protein_59 | IS6 family transposase | - |
| ML258_RS28450 (44731) | 44731..47697 | - | 2967 | WP_001138014.1 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| ML258_RS28455 (47701) | 47701..48261 | - | 561 | WP_001161490.1 | Tn3 family transposase TnpR_TnAs1 | Transposase |
| ML258_RS28460 (48653) | 48653..49270 | + | 618 | Protein_62 | replication protein | - |
| ML258_RS28465 (49804) | 49804..50082 | + | 279 | WP_013213990.1 | hypothetical protein | - |
| ML258_RS28470 (50193) | 50193..50618 | + | 426 | WP_013213989.1 | antirestriction protein | - |
| ML258_RS28475 (50746) | 50746..50901 | + | 156 | WP_013213988.1 | hypothetical protein | - |
| ML258_RS28480 (50947) | 50947..51243 | + | 297 | WP_013213987.1 | transcriptional regulator | - |
| ML258_RS28485 (51347) | 51347..52228 | + | 882 | Protein_67 | IS1182 family transposase ISKpn6 | Transposase |
| ML258_RS28490 (52478) | 52478..53359 | - | 882 | WP_004199234.1 | Carbapenem-hydrolyzing beta-lactamase KPC | ARG |
| ML258_RS28495 (53635) | 53635..54615 | - | 981 | WP_013213985.1 | IS481 family transposase ISKpn27 | Transposase |
| ML258_RS28500 (54738) | 54738..55199 | - | 462 | Protein_70 | Tn3 family transposase TnpR_Tn3 | Transposase |
| ML258_RS28505 (55251) | 55251..55955 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| ML258_RS28510 (56020) | 56020..57192 | - | 1173 | Protein_72 | transposase | - |
| ML258_RS28515 (57267) | 57267..57935 | - | 669 | WP_001300294.1 | putative signaling protein | VF |
| ML258_RS28520 (57971) | 57971..58207 | - | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| ML258_RS28525 (58204) | 58204..58566 | - | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| ML258_RS28530 (58584) | 58584..60278 | - | 1695 | WP_000105636.1 | mercury(II) reductase | - |
| ML258_RS28535 (60330) | 60330..60752 | - | 423 | WP_001340589.1 | organomercurial transporter MerC | - |
| ML258_RS28540 (60788) | 60788..61063 | - | 276 | WP_000732292.1 | mercury resistance system periplasmic binding protein MerP | - |
| ML258_RS28545 (61077) | 61077..61427 | - | 351 | WP_001294663.1 | mercuric transport protein MerT | - |
| ML258_RS28550 (61499) | 61499..61933 | + | 435 | WP_000429836.1 | IS607 family transposase ISChh1 | Transposase |
| ML258_RS28555 (62012) | 62012..63016 | + | 1005 | WP_000427619.1 | IS110 family transposase IS5075 | Transposase |
| ML258_RS28560 (63544) | 63544..64944 | - | 1401 | WP_004152084.1 | copper resistance membrane spanning protein PcoS | - |
| ML258_RS28565 (64941) | 64941..65621 | - | 681 | WP_001188930.1 | Transcriptional activator protein CopR | VF |
| ML258_RS28570 (65676) | 65676..66605 | - | 930 | WP_004213583.1 | copper resistance inner membrane protein PcoD | - |
| ML258_RS28575 (66610) | 66610..66990 | - | 381 | WP_000025662.1 | copper resistance system metallochaperone PcoC | - |
| ML258_RS28580 (67030) | 67030..67920 | - | 891 | WP_029884201.1 | copper resistance outer membrane transporter PcoB | - |
| ML258_RS28585 (67926) | 67926..69743 | - | 1818 | WP_004213580.1 | multicopper oxidase PcoA | - |
| ML258_RS28590 (69977) | 69977..70444 | + | 468 | WP_048336866.1 | hypothetical protein | - |
| ML258_RS28595 (70711) | 70711..71448 | + | 738 | WP_004118669.1 | Murein DD-endopeptidase MepM | VF |
| ML258_RS28600 (71482) | 71482..71679 | - | 198 | WP_000843497.1 | DUF2933 domain-containing protein | - |
| ML258_RS28605 (71720) | 71720..74167 | - | 2448 | WP_004098955.1 | Ag(+)-translocating P-type ATPase SilP | - |
| ML258_RS28610 (74294) | 74294..74734 | - | 441 | WP_000758228.1 | DUF411 domain-containing protein | - |
| ML258_RS28615 (74821) | 74821..77967 | - | 3147 | WP_004098958.1 | Cu(+)/Ag(+) efflux RND transporter permease subunit SilA | - |
| ML258_RS28620 (77978) | 77978..79270 | - | 1293 | WP_004213579.1 | Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB | - |
| ML258_RS28625 (79384) | 79384..79746 | - | 363 | WP_004213578.1 | cation efflux system protein CusF | - |
| ML258_RS28630 (79775) | 79775..81160 | - | 1386 | WP_004213577.1 | Cation efflux system protein CusC | VF |
| ML258_RS28635 (81350) | 81350..82030 | + | 681 | WP_004213574.1 | Transcriptional regulatory protein CusR | VF |
| ML258_RS28640 (82023) | 82023..83498 | + | 1476 | WP_000555737.1 | copper/silver sensor histidine kinase SilS | - |
| ML258_RS28645 (83749) | 83749..84180 | + | 432 | WP_023302802.1 | silver-binding protein SilE | - |
| ML258_RS28650 (84324) | 84324..84674 | + | 351 | WP_004213569.1 | DUF305 domain-containing protein | - |
| ML258_RS28655 (85061) | 85061..85969 | - | 909 | WP_023302803.1 | HNH endonuclease | - |
| ML258_RS28660 (86606) | 86606..87580 | + | 975 | WP_004213565.1 | sensor domain-containing diguanylate cyclase | - |
| ML258_RS28665 (87759) | 87759..88004 | + | 246 | Protein_103 | hypothetical protein | - |
| ML258_RS28670 (88165) | 88165..89109 | + | 945 | WP_011977810.1 | hypothetical protein | - |
| ML258_RS28675 (89146) | 89146..89538 | + | 393 | WP_011977811.1 | hypothetical protein | - |
| ML258_RS28680 (89596) | 89596..90117 | + | 522 | WP_013214008.1 | hypothetical protein | - |
| ML258_RS28685 (90163) | 90163..90366 | + | 204 | WP_011977813.1 | hypothetical protein | - |
| ML258_RS28690 (90396) | 90396..91400 | + | 1005 | WP_011977814.1 | hypothetical protein | - |
| ML258_RS28695 (91584) | 91584..92363 | + | 780 | WP_013214009.1 | site-specific integrase | - |
| ML258_RS28700 (92409) | 92409..92666 | - | 258 | WP_013214010.1 | hypothetical protein | - |
| ML258_RS28705 (92795) | 92795..92908 | - | 114 | WP_014343462.1 | hypothetical protein | - |
| ML258_RS28710 (93444) | 93444..94310 | + | 867 | WP_004118283.1 | replication initiation protein | - |
| ML258_RS28715 (95420) | 95420..96625 | + | 1206 | WP_011977818.1 | AAA family ATPase | - |
| ML258_RS28720 (96625) | 96625..97599 | + | 975 | WP_011977819.1 | ParB family protein | - |
| ML258_RS28725 (97681) | 97681..98952 | - | 1272 | WP_013214011.1 | Y-family DNA polymerase | - |
| ML258_RS28730 (98952) | 98952..99383 | - | 432 | WP_001568036.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| ML258_RS28735 (99790) | 99790..101277 | + | 1488 | WP_004178082.1 | group II intron reverse transcriptase/maturase | - |
| ML258_RS28740 (101526) | 101526..102497 | + | 972 | WP_004152353.1 | plasmid segregation protein ParM | - |
| ML258_RS28745 (102500) | 102500..103171 | + | 672 | WP_013214012.1 | plasmid partitioning/stability family protein | - |
| ML258_RS28750 (103234) | 103234..103464 | + | 231 | WP_001568040.1 | hypothetical protein | - |
| ML258_RS28755 (103660) | 103660..103829 | + | 170 | Protein_121 | hypothetical protein | - |
| ML258_RS28760 (103901) | 103901..104602 | + | 702 | WP_001568041.1 | DNA methylase | - |
| ML258_RS28765 (104602) | 104602..104823 | + | 222 | WP_001568042.1 | hypothetical protein | - |
| ML258_RS28770 (104833) | 104833..105252 | + | 420 | WP_001568043.1 | DUF1380 domain-containing protein | - |
| ML258_RS28775 (105306) | 105306..106073 | + | 768 | WP_013214013.1 | hypothetical protein | - |
| ML258_RS28780 (106754) | 106754..107182 | + | 429 | WP_001568045.1 | antirestriction protein | - |
| ML258_RS28785 (107225) | 107225..107731 | + | 507 | WP_013214014.1 | antirestriction protein ArdA | - |
| ML258_RS28790 (107774) | 107774..107965 | + | 192 | WP_001568047.1 | hypothetical protein | - |
| ML258_RS28795 (108153) | 108153..108407 | + | 255 | WP_011977779.1 | DNA polymerase III subunit theta | - |
| ML258_RS28800 (108442) | 108442..108762 | + | 321 | WP_001568049.1 | hypothetical protein | - |
| ML258_RS28805 (109443) | 109443..109670 | + | 228 | WP_001568050.1 | hypothetical protein | - |
| ML258_RS28810 (109762) | 109762..109992 | + | 231 | WP_001568051.1 | hypothetical protein | - |
| ML258_RS28815 (110044) | 110044..111399 | + | 1356 | WP_014343515.1 | DUF3560 domain-containing protein | - |
| ML258_RS28820 (111447) | 111447..112010 | + | 564 | WP_014343514.1 | methyltransferase | - |
| ML258_RS28825 (112843) | 112843..113385 | + | 543 | WP_014343512.1 | single-stranded DNA-binding protein | - |
| ML258_RS28830 (113434) | 113434..113682 | + | 249 | WP_001568055.1 | DUF905 domain-containing protein | - |
| ML258_RS28835 (113752) | 113752..115809 | + | 2058 | WP_015493064.1 | ParB/RepB/Spo0J family partition protein | - |
| ML258_RS28840 (115854) | 115854..116285 | + | 432 | WP_001568057.1 | conjugation system SOS inhibitor PsiB | - |
| ML258_RS28845 (116282) | 116282..117010 | + | 729 | WP_001568058.1 | plasmid SOS inhibition protein A | - |
| ML258_RS28850 (117007) | 117007..117333 | + | 327 | WP_013023807.1 | hypothetical protein | - |
| ML258_RS28855 (117389) | 117389..117763 | + | 375 | WP_014343510.1 | hypothetical protein | - |
| ML258_RS28860 (117933) | 117933..118085 | + | 153 | WP_004150508.1 | DUF5431 family protein | - |
| ML258_RS28865 (118030) | 118030..118149 | + | 120 | WP_159376494.1 | type I toxin-antitoxin system Hok family toxin | - |
| ML258_RS28870 (118842) | 118842..119114 | + | 273 | WP_040245921.1 | hypothetical protein | - |
| ML258_RS28875 (119111) | 119111..119461 | + | 351 | WP_040245917.1 | hypothetical protein | - |
| ML258_RS28880 (119476) | 119476..119793 | + | 318 | WP_014343505.1 | hypothetical protein | - |
| ML258_RS28885 (120634) | 120634..120990 | + | 357 | WP_014343501.1 | hypothetical protein | - |
| ML258_RS28890 (121051) | 121051..121263 | + | 213 | WP_014343500.1 | hypothetical protein | - |
| ML258_RS28895 (121274) | 121274..121498 | + | 225 | WP_014343499.1 | hypothetical protein | - |
| ML258_RS28900 (121579) | 121579..121899 | + | 321 | WP_014343498.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| ML258_RS28905 (121889) | 121889..122167 | + | 279 | WP_004152721.1 | helix-turn-helix transcriptional regulator | - |
| ML258_RS28910 (122171) | 122171..122275 | + | 105 | Protein_152 | transcriptional regulator | - |
| ML258_RS28915 (123106) | 123106..123927 | + | 822 | WP_004152492.1 | DUF932 domain-containing protein | - |
| ML258_RS28920 (123960) | 123960..124289 | + | 330 | WP_013214015.1 | DUF5983 family protein | - |
| ML258_RS28925 (124322) | 124322..124807 | - | 486 | WP_014343495.1 | hypothetical protein | VF |
| ML258_RS28930 (125198) | 125198..125614 | + | 417 | WP_014343494.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| ML258_RS28935 (125814) | 125814..126551 | + | 738 | WP_154244330.1 | conjugal transfer protein TrbJ | - |
| ML258_RS28940 (126666) | 126666..126872 | + | 207 | WP_171773970.1 | TraY domain-containing protein | - |
| ML258_RS28945 (126934) | 126934..127302 | + | 369 | WP_004194426.1 | type IV conjugative transfer system pilin TraA | - |
| ML258_RS28950 (127316) | 127316..127621 | + | 306 | WP_004144424.1 | type IV conjugative transfer system protein TraL | - |
| ML258_RS28955 (127641) | 127641..128006 | + | 366 | Protein_161 | type IV conjugative transfer system protein TraE | - |
| ML258_RS28960 (128061) | 128061..128405 | - | 345 | Protein_162 | IS6 family transposase IS26 | Transposase |
| ML258_RS28965 (128457) | 128457..129161 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| ML258_RS28970 (129186) | 129186..129386 | + | 201 | WP_072354025.1 | hypothetical protein | - |
| ML258_RS28975 (129406) | 129406..130152 | + | 747 | WP_000205770.1 | conjugal transfer pilus acetylase TraX | - |
| ML258_RS28980 (130207) | 130207..130767 | + | 561 | WP_000139328.1 | fertility inhibition protein FinO | - |
| ML258_RS28985 (130899) | 130899..131099 | + | 201 | WP_015059022.1 | hypothetical protein | - |
| ML258_RS28990 (131485) | 131485..132084 | + | 600 | WP_032083981.1 | PIN domain-containing protein | - |
| ML258_RS28995 (132146) | 132146..132478 | + | 333 | WP_152916585.1 | hypothetical protein | - |
| - (132679) | 132679..132738 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| - (132679) | 132679..132738 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| - (132679) | 132679..132738 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| - (132679) | 132679..132738 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| ML258_RS29000 (132783) | 132783..132932 | + | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| ML258_RS29005 (133216) | 133216..133464 | + | 249 | WP_000083837.1 | replication regulatory protein RepA | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|