MGE detailed information
MGE type: Conjugative plasmid MGE length: 171047 bp
Accession: NZ_CP092654 Location: 1..171047 Organism: Klebsiella pneumoniae strain NB5 Replicon: plasmid pNB5_3
Accession: NZ_CP092654 Location: 1..171047 Organism: Klebsiella pneumoniae strain NB5 Replicon: plasmid pNB5_3
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MJ642_RS01880 | 1..1011 | + | 1011 | WP_004152063.1 | RepB family plasmid replication initiator protein | - |
| MJ642_RS01885 | 1728..2468 | - | 741 | WP_001515717.1 | tyrosine-type recombinase/integrase | - |
| MJ642_RS01890 | 3612..4559 | + | 948 | WP_004152065.1 | sensor domain-containing diguanylate cyclase | - |
| MJ642_RS01895 | 4586..4897 | - | 312 | WP_071527918.1 | EAL domain-containing protein | - |
| MJ642_RS01900 | 4917..5885 | + | 969 | WP_074424273.1 | IS5 family transposase IS903B | Transposase |
| MJ642_RS01905 | 6558..6815 | - | 258 | WP_004197688.1 | hypothetical protein | - |
| MJ642_RS01910 | 7456..7971 | + | 516 | Protein_6 | putative cyclic di-GMP phosphodiesterase PdeB | VF |
| MJ642_RS01915 | 8035..8871 | + | 837 | WP_004152068.1 | putative cyclic di-GMP phosphodiesterase PdeB | VF |
| MJ642_RS01920 | 9854..11131 | - | 1278 | WP_004152070.1 | DUF2254 domain-containing protein | - |
| MJ642_RS01925 | 11194..13191 | - | 1998 | WP_004178088.1 | choline BCCT transporter BetT | - |
| MJ642_RS01940 | 15529..16013 | + | 485 | Protein_12 | IS1 family transposase IS1X2 | Transposase |
| MJ642_RS01945 | 16029..16571 | + | 543 | Protein_13 | ISL3 family transposase ISKpn25 | Transposase |
| MJ642_RS01950 | 16867..17298 | - | 432 | WP_004178091.1 | silver-binding protein SilE | - |
| MJ642_RS01955 | 17549..19024 | - | 1476 | WP_003032875.1 | copper/silver sensor histidine kinase SilS | - |
| MJ642_RS01960 | 19017..19697 | - | 681 | WP_001572351.1 | Transcriptional regulatory protein CusR | VF |
| MJ642_RS01965 | 19887..21272 | + | 1386 | WP_238050199.1 | Cation efflux system protein CusC | VF |
| MJ642_RS01970 | 21301..21654 | + | 354 | WP_001246153.1 | cation efflux system protein CusF | - |
| MJ642_RS01975 | 21768..23060 | + | 1293 | WP_004152079.1 | Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB | - |
| MJ642_RS01980 | 23071..26217 | + | 3147 | WP_004098958.1 | Cu(+)/Ag(+) efflux RND transporter permease subunit SilA | - |
| MJ642_RS01985 | 26304..26744 | + | 441 | WP_000758228.1 | DUF411 domain-containing protein | - |
| MJ642_RS01990 | 26871..29318 | + | 2448 | WP_004098955.1 | Ag(+)-translocating P-type ATPase SilP | - |
| MJ642_RS01995 | 29359..29556 | + | 198 | WP_000843497.1 | DUF2933 domain-containing protein | - |
| MJ642_RS02000 | 29590..30327 | - | 738 | WP_004118669.1 | Murein DD-endopeptidase MepM | VF |
| MJ642_RS02005 | 30616..31065 | - | 450 | WP_001023257.1 | copper resistance protein | - |
| MJ642_RS02010 | 31354..32334 | - | 981 | WP_000019473.1 | IS5 family transposase ISKpn26 | Transposase |
| MJ642_RS02015 | 32499..34316 | + | 1818 | WP_000925242.1 | multicopper oxidase PcoA | - |
| MJ642_RS02020 | 34322..35212 | + | 891 | WP_001378118.1 | copper resistance outer membrane transporter PcoB | - |
| MJ642_RS02025 | 35252..35632 | + | 381 | WP_000025662.1 | copper resistance system metallochaperone PcoC | - |
| MJ642_RS02030 | 35637..36566 | + | 930 | WP_004118344.1 | copper resistance inner membrane protein PcoD | - |
| MJ642_RS02035 | 36621..37301 | + | 681 | WP_001188930.1 | Transcriptional activator protein CopR | VF |
| MJ642_RS02040 | 37298..38698 | + | 1401 | WP_004152084.1 | copper resistance membrane spanning protein PcoS | - |
| MJ642_RS02045 | 38915..39349 | + | 435 | WP_004152085.1 | copper resistance system metallochaperone PcoE | - |
| MJ642_RS02050 | 39581..39760 | - | 180 | WP_004152086.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| MJ642_RS02055 | 39821..41441 | - | 1621 | Protein_35 | ISL3 family transposase | - |
| MJ642_RS02060 | 41503..42012 | + | 510 | WP_031944101.1 | aquaporin | - |
| MJ642_RS02065 | 42062..42559 | - | 498 | WP_004152091.1 | GNAT family N-acetyltransferase | - |
| MJ642_RS02070 | 42891..43217 | + | 327 | WP_004152092.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| MJ642_RS02075 | 43214..43927 | + | 714 | WP_004152093.1 | arsenical resistance protein ArsH | - |
| MJ642_RS02080 | 43936..44481 | + | 546 | WP_004182005.1 | sigma-70 family RNA polymerase sigma factor | - |
| MJ642_RS02085 | 44557..44919 | + | 363 | WP_004152095.1 | arsenic metallochaperone ArsD family protein | - |
| MJ642_RS02090 | 44938..46694 | + | 1757 | Protein_42 | arsenical pump-driving ATPase | - |
| MJ642_RS02095 | 46816..47352 | + | 537 | WP_004152096.1 | GNAT family N-acetyltransferase | - |
| MJ642_RS02100 | 47385..47810 | - | 426 | WP_004152097.1 | glutaredoxin-dependent arsenate reductase | - |
| MJ642_RS02105 | 47823..49112 | - | 1290 | WP_004152098.1 | arsenite efflux transporter membrane subunit ArsB | - |
| MJ642_RS02110 | 49160..50911 | - | 1752 | WP_004152099.1 | Arsenical pump-driving ATPase | VF |
| MJ642_RS02115 | 50929..51291 | - | 363 | WP_004152100.1 | arsenite efflux transporter metallochaperone ArsD | - |
| MJ642_RS02120 | 51341..51691 | - | 351 | WP_004152101.1 | As(III)-sensing metalloregulatory transcriptional repressor ArsR | - |
| MJ642_RS02125 | 52049..52318 | + | 270 | WP_004152102.1 | hypothetical protein | - |
| MJ642_RS02130 | 52306..52881 | + | 576 | WP_004152103.1 | hypothetical protein | - |
| MJ642_RS02135 | 52912..53406 | + | 495 | WP_004152104.1 | DNA-binding protein | - |
| MJ642_RS02140 | 53450..53818 | + | 369 | WP_004152105.1 | hypothetical protein | - |
| MJ642_RS02145 | 53852..54055 | + | 204 | WP_004152106.1 | HHA domain-containing protein | - |
| MJ642_RS02150 | 54104..54361 | + | 258 | WP_004152107.1 | hypothetical protein | - |
| MJ642_RS02155 | 54437..54691 | + | 255 | WP_004152108.1 | hypothetical protein | - |
| MJ642_RS02160 | 54867..55133 | + | 267 | WP_003026799.1 | DUF1778 domain-containing protein | Antitoxin Detail |
| MJ642_RS02165 | 55121..55603 | + | 483 | WP_003026803.1 | GNAT family N-acetyltransferase | Toxin Detail |
| MJ642_RS02170 | 55804..57207 | + | 1404 | WP_001567368.1 | ISNCY family transposase ISKpn21 | Transposase |
| MJ642_RS02175 | 57236..57868 | - | 633 | WP_001567369.1 | hypothetical protein | - |
| MJ642_RS02180 | 58098..59444 | + | 1347 | WP_020314316.1 | ISNCY family transposase ISLad2 | Transposase |
| MJ642_RS29145 | 59605..59736 | + | 132 | WP_004218042.1 | hypothetical protein | - |
| MJ642_RS02185 | 59945..61110 | - | 1166 | Protein_62 | IS3 family transposase ISKpn38 | Transposase |
| MJ642_RS02190 | 61287..62249 | - | 963 | WP_004152113.1 | zinc metalloprotease HtpX | - |
| MJ642_RS02195 | 62236..62724 | - | 489 | WP_004152114.1 | phosphate-starvation-inducible PsiE family protein | - |
| MJ642_RS02200 | 62839..62985 | - | 147 | Protein_65 | diguanylate cyclase | - |
| MJ642_RS02205 | 63223..63420 | - | 198 | WP_004152115.1 | hypothetical protein | - |
| MJ642_RS02210 | 63420..66215 | - | 2796 | WP_004152116.1 | ATP-dependent Clp protease ATP-binding subunit ClpC | VF |
| MJ642_RS02215 | 66330..66899 | - | 570 | WP_004152117.1 | Spore protein SP21 | VF |
| MJ642_RS02220 | 66934..67215 | - | 282 | WP_004152118.1 | helix-turn-helix domain-containing protein | - |
| MJ642_RS02225 | 67459..67722 | - | 264 | WP_004118208.1 | hypothetical protein | - |
| MJ642_RS02230 | 67737..68000 | + | 264 | WP_004118209.1 | transposase | - |
| MJ642_RS02235 | 67945..68061 | + | 117 | Protein_72 | transposase domain-containing protein | - |
| MJ642_RS02240 | 68246..68943 | + | 698 | WP_223174644.1 | IS1 family transposase IS1X2 | Transposase |
| MJ642_RS02245 | 69202..70182 | + | 981 | WP_000019473.1 | IS5 family transposase ISKpn26 | Transposase |
| MJ642_RS02250 | 70764..71283 | - | 520 | Protein_75 | IS5 family transposase ISPst7 | Transposase |
| MJ642_RS02255 | 71391..72260 | - | 870 | WP_004152692.1 | HTH-type transcriptional activator CmpR | VF |
| MJ642_RS02260 | 72254..73264 | - | 1011 | WP_004152693.1 | phosphonate dehydrogenase PtxD | - |
| MJ642_RS02265 | 73273..74100 | - | 828 | WP_004152694.1 | phosphonate ABC transporter, permease protein PhnE | - |
| MJ642_RS02270 | 74109..74972 | - | 864 | WP_004152695.1 | phosphate/phosphite/phosphonate ABC transporter substrate-binding protein | - |
| MJ642_RS02275 | 74969..75796 | - | 828 | WP_004153729.1 | Glutamine transport ATP-binding protein GlnQ | VF |
| MJ642_RS02280 | 76138..76446 | + | 309 | Protein_81 | IS5 family transposase ISThi1 | Transposase |
| MJ642_RS02285 | 76652..77356 | - | 705 | WP_004217321.1 | IS6 family transposase IS26 | Transposase |
| MJ642_RS02290 | 77347..78612 | + | 1266 | WP_004198116.1 | Tn3 family transposase TnpA_ISSba14 | Transposase |
| MJ642_RS02295 | 78691..79695 | + | 1005 | WP_000427623.1 | IS110 family transposase IS4321R | Transposase |
| MJ642_RS02300 | 79987..80655 | + | 669 | WP_044117068.1 | IS6 family transposase IS26 | Transposase |
| MJ642_RS02305 | 80845..81660 | - | 816 | WP_000018329.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| MJ642_RS02310 | 81811..82515 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| MJ642_RS02315 | 82637..83542 | + | 906 | WP_000219391.1 | hypothetical protein | ARG |
| MJ642_RS02320 | 83539..84778 | + | 1240 | Protein_89 | macrolide resistance MFS transporter Mrx(A) | - |
| MJ642_RS02325 | 84778..85362 | + | 585 | WP_001137892.1 | macrolide-binding transcriptional repressor MphR(A) | - |
| MJ642_RS02330 | 85855..86619 | - | 765 | WP_001389365.1 | IS6 family transposase IS6100 | Transposase |
| MJ642_RS02335 | 86789..87493 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| MJ642_RS02340 | 87559..89073 | + | 1515 | Protein_93 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| MJ642_RS02345 | 89106..90164 | + | 1059 | Protein_94 | lactose permease | - |
| MJ642_RS02350 | 90256..91225 | + | 970 | Protein_95 | IS5 family transposase IS903 | Transposase |
| MJ642_RS02355 | 91870..94179 | + | 2310 | WP_004152290.1 | TerB N-terminal domain-containing protein | - |
| MJ642_RS02360 | 94183..95499 | + | 1317 | WP_004152291.1 | ATP-binding protein | - |
| MJ642_RS02365 | 95496..97691 | + | 2196 | WP_000093087.1 | DEAD/DEAH box helicase | - |
| MJ642_RS02370 | 99138..99995 | - | 858 | WP_004152292.1 | incFII family plasmid replication initiator RepA | - |
| MJ642_RS02375 | 100282..100560 | - | 279 | WP_004199332.1 | replication regulatory protein RepA | - |
| MJ642_RS02380 | 100881..101432 | - | 552 | WP_004152294.1 | Phospholipase D | VF |
| MJ642_RS02385 | 101537..101617 | - | 81 | Protein_102 | hypothetical protein | - |
| MJ642_RS02390 | 101701..101979 | - | 279 | WP_004152296.1 | bacteriocin immunity protein | - |
| MJ642_RS02395 | 101981..104302 | - | 2322 | WP_004178051.1 | klebicin B-related nuclease bacteriocin | - |
| MJ642_RS02400 | 104659..105204 | + | 546 | WP_004178052.1 | hypothetical protein | - |
| MJ642_RS02405 | 105432..105779 | - | 348 | WP_004152301.1 | DUF6404 family protein | - |
| MJ642_RS02410 | 105799..106395 | - | 597 | WP_004178053.1 | fertility inhibition protein FinO | - |
| MJ642_RS02415 | 106553..107278 | - | 726 | WP_004152303.1 | type-F conjugative transfer system pilin acetylase TraX | - |
| MJ642_RS02420 | 107358..112619 | - | 5262 | WP_004153029.1 | Multifunctional conjugation protein TraI | Relaxase |
| MJ642_RS02425 | 112619..114928 | - | 2310 | WP_004152630.1 | type IV conjugative transfer system coupling protein TraD | - |
| MJ642_RS02430 | 115288..116019 | - | 732 | WP_004152629.1 | conjugal transfer complement resistance protein TraT | - |
| MJ642_RS02435 | 116209..116736 | - | 528 | WP_004153030.1 | hypothetical protein | - |
| MJ642_RS02440 | 116880..117577 | + | 698 | WP_095033700.1 | IS1 family transposase IS1R | Transposase |
| MJ642_RS02445 | 117588..120368 | - | 2781 | WP_137922717.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| MJ642_RS02450 | 120368..121738 | - | 1371 | WP_004178055.1 | conjugal transfer pilus assembly protein TraH | - |
| MJ642_RS02455 | 121725..122153 | - | 429 | WP_004152689.1 | hypothetical protein | - |
| MJ642_RS02460 | 122146..122718 | - | 573 | WP_004152688.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| MJ642_RS02465 | 122690..122929 | - | 240 | WP_004152687.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| MJ642_RS02470 | 122940..123692 | - | 753 | WP_004152686.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| MJ642_RS02475 | 123713..124039 | - | 327 | WP_004152685.1 | hypothetical protein | - |
| MJ642_RS02480 | 124267..124503 | - | 237 | WP_004152683.1 | conjugal transfer protein TrbE | - |
| MJ642_RS02485 | 124535..126490 | - | 1956 | WP_004153093.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| MJ642_RS02490 | 126538..127176 | - | 639 | WP_004152682.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| MJ642_RS02495 | 127189..128148 | - | 960 | WP_015065634.1 | conjugal transfer pilus assembly protein TraU | - |
| MJ642_RS02500 | 128192..128818 | - | 627 | WP_004152590.1 | type-F conjugative transfer system protein TraW | - |
| MJ642_RS02505 | 128818..129207 | - | 390 | WP_004152591.1 | type-F conjugative transfer system protein TrbI | - |
| MJ642_RS02510 | 129207..131846 | - | 2640 | WP_004152592.1 | type IV secretion system protein TraC | - |
| MJ642_RS02515 | 131918..132316 | - | 399 | WP_004153071.1 | hypothetical protein | - |
| MJ642_RS02520 | 132612..133016 | - | 405 | WP_004152594.1 | hypothetical protein | - |
| MJ642_RS02525 | 133083..133400 | - | 318 | WP_004152595.1 | hypothetical protein | - |
| MJ642_RS02530 | 133401..133619 | - | 219 | WP_004171484.1 | hypothetical protein | - |
| MJ642_RS02535 | 133643..133933 | - | 291 | WP_004152596.1 | hypothetical protein | - |
| MJ642_RS02540 | 133938..134348 | - | 411 | WP_004152597.1 | lipase chaperone | - |
| MJ642_RS02545 | 134480..135049 | - | 570 | WP_004152598.1 | type IV conjugative transfer system lipoprotein TraV | - |
| MJ642_RS02550 | 135072..135668 | - | 597 | WP_004152599.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| MJ642_RS02555 | 135661..137086 | - | 1426 | Protein_136 | F-type conjugal transfer pilus assembly protein TraB | - |
| MJ642_RS02560 | 137086..137826 | - | 741 | WP_004152601.1 | type-F conjugative transfer system secretin TraK | - |
| MJ642_RS02565 | 137813..138379 | - | 567 | WP_004152602.1 | type IV conjugative transfer system protein TraE | - |
| MJ642_RS02570 | 138399..138704 | - | 306 | WP_004178059.1 | type IV conjugative transfer system protein TraL | - |
| MJ642_RS02575 | 138718..139086 | - | 369 | WP_004178060.1 | type IV conjugative transfer system pilin TraA | - |
| MJ642_RS02580 | 139140..139511 | - | 372 | WP_004208838.1 | TraY domain-containing protein | - |
| MJ642_RS02585 | 139595..140290 | - | 696 | WP_004178061.1 | transcriptional regulator TraJ family protein | - |
| MJ642_RS02590 | 140504..140659 | - | 156 | Protein_143 | relaxosome protein TraM | - |
| MJ642_RS02595 | 140695..141663 | + | 969 | WP_072198477.1 | IS5 family transposase IS903B | Transposase |
| MJ642_RS02600 | 141725..141967 | - | 243 | Protein_145 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| MJ642_RS02605 | 142395..142880 | + | 486 | WP_004178063.1 | hypothetical protein | VF |
| MJ642_RS02610 | 142913..143242 | - | 330 | WP_011977736.1 | DUF5983 family protein | - |
| MJ642_RS02615 | 143275..144096 | - | 822 | WP_004178064.1 | DUF932 domain-containing protein | - |
| MJ642_RS02620 | 144930..145343 | - | 414 | WP_004152722.1 | helix-turn-helix domain-containing protein | - |
| MJ642_RS02625 | 145344..145622 | - | 279 | WP_004152721.1 | helix-turn-helix transcriptional regulator | - |
| MJ642_RS02630 | 145612..145932 | - | 321 | WP_004152720.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| MJ642_RS02635 | 146013..146237 | - | 225 | WP_004152719.1 | hypothetical protein | - |
| MJ642_RS02640 | 146248..146460 | - | 213 | WP_004152718.1 | hypothetical protein | - |
| MJ642_RS02645 | 146521..146877 | - | 357 | WP_004152717.1 | hypothetical protein | - |
| MJ642_RS02650 | 147513..147863 | - | 351 | WP_137922726.1 | hypothetical protein | - |
| MJ642_RS02655 | 147860..148132 | - | 273 | WP_004152759.1 | hypothetical protein | - |
| MJ642_RS02660 | 148832..148993 | - | 162 | WP_004118124.1 | type I toxin-antitoxin system Hok family toxin | - |
| MJ642_RS02665 | 149065..150144 | + | 1080 | WP_004220208.1 | IS481 family transposase ISKpn28 | Transposase |
| MJ642_RS02670 | 150322..150696 | - | 375 | WP_004152638.1 | hypothetical protein | - |
| MJ642_RS02675 | 150752..151078 | - | 327 | WP_004152639.1 | hypothetical protein | - |
| MJ642_RS02680 | 151075..151803 | - | 729 | WP_004152640.1 | plasmid SOS inhibition protein A | - |
| MJ642_RS02685 | 151800..152231 | - | 432 | WP_004152641.1 | conjugation system SOS inhibitor PsiB | - |
| MJ642_RS02690 | 152276..154334 | - | 2059 | Protein_163 | ParB/RepB/Spo0J family partition protein | - |
| MJ642_RS02695 | 154404..154652 | - | 249 | WP_004152643.1 | DUF905 domain-containing protein | - |
| MJ642_RS02700 | 154701..155243 | - | 543 | WP_004152644.1 | single-stranded DNA-binding protein | - |
| MJ642_RS02705 | 156019..156582 | - | 564 | WP_004152645.1 | methyltransferase | - |
| MJ642_RS02710 | 156630..157985 | - | 1356 | WP_004178068.1 | DUF3560 domain-containing protein | - |
| MJ642_RS02715 | 158037..158267 | - | 231 | WP_004198570.1 | hypothetical protein | - |
| MJ642_RS02720 | 158359..158586 | - | 228 | WP_004178072.1 | hypothetical protein | - |
| MJ642_RS02725 | 159368..159685 | - | 318 | WP_004118473.1 | hypothetical protein | - |
| MJ642_RS02730 | 159720..159974 | - | 255 | WP_004152754.1 | DNA polymerase III subunit theta | - |
| MJ642_RS02735 | 160211..160636 | - | 426 | WP_004118478.1 | antirestriction protein | - |
| MJ642_RS02740 | 161157..161387 | - | 231 | WP_004152753.1 | hypothetical protein | - |
| MJ642_RS02745 | 161621..163108 | - | 1488 | WP_004178082.1 | group II intron reverse transcriptase/maturase | - |
| MJ642_RS02750 | 163511..163936 | + | 426 | WP_004178083.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| MJ642_RS02755 | 163936..165207 | + | 1272 | WP_004152715.1 | Y-family DNA polymerase | - |
| MJ642_RS02760 | 165346..165501 | + | 156 | WP_001776126.1 | hypothetical protein | - |
| MJ642_RS02765 | 165524..166722 | - | 1199 | Protein_178 | IS200-IS605 family transposase IS609 | Transposase |
| MJ642_RS02770 | 168159..169130 | - | 972 | WP_004152062.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| MJ642_RS02775 | 169130..170296 | - | 1167 | WP_000523813.1 | Sporulation initiation inhibitor protein Soj | VF |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|