MGE detailed information

MGE type: Conjugative plasmid        MGE length: 158444 bp
Accession: NZ_CP086418        Location: 1..158444         Organism: Klebsiella pneumoniae strain AE-2247421-T20-ESBL       Replicon: plasmid p2247421-T20-ESBL_2


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LNN42_RS27670 (LNN42_27675) 1..1011 + 1011 WP_004152063.1 RepB family plasmid replication initiator protein -
LNN42_RS27675 (LNN42_27680) 1728..2468 - 741 WP_001515717.1 tyrosine-type recombinase/integrase -
LNN42_RS27680 (LNN42_27685) 3612..4559 + 948 WP_004152065.1 sensor domain-containing diguanylate cyclase -
LNN42_RS27685 (LNN42_27690) 4586..4897 - 312 WP_071527918.1 EAL domain-containing protein -
LNN42_RS27690 (LNN42_27695) 4917..5885 + 969 WP_011977741.1 IS5 family transposase IS903B Transposase
LNN42_RS27695 (LNN42_27700) 6558..6815 - 258 WP_004197688.1 hypothetical protein -
LNN42_RS27700 (LNN42_27705) 7456..7971 + 516 Protein_6 putative cyclic di-GMP phosphodiesterase PdeB VF
LNN42_RS27705 (LNN42_27710) 8035..8871 + 837 WP_004178087.1 putative cyclic di-GMP phosphodiesterase PdeB VF
LNN42_RS27710 (LNN42_27715) 9854..11131 - 1278 WP_004152070.1 DUF2254 domain-containing protein -
LNN42_RS27715 (LNN42_27720) 11194..13191 - 1998 WP_004178088.1 choline BCCT transporter BetT -
LNN42_RS27730 (LNN42_27735) 15529..16013 + 485 Protein_12 IS1 family transposase IS1X2 Transposase
LNN42_RS27735 (LNN42_27740) 16029..16571 + 543 Protein_13 ISL3 family transposase ISKpn25 Transposase
LNN42_RS27740 (LNN42_27745) 16867..17298 - 432 WP_004178091.1 silver-binding protein SilE -
LNN42_RS27745 (LNN42_27750) 17549..19024 - 1476 WP_003032875.1 copper/silver sensor histidine kinase SilS -
LNN42_RS27750 (LNN42_27755) 19017..19697 - 681 WP_001572351.1 Transcriptional regulatory protein CusR VF
LNN42_RS27755 (LNN42_27760) 19887..21272 + 1386 WP_000475512.1 Cation efflux system protein CusC VF
LNN42_RS27760 (LNN42_27765) 21301..21654 + 354 WP_001246153.1 cation efflux system protein CusF -
LNN42_RS27765 (LNN42_27770) 21768..23060 + 1293 WP_004152079.1 Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB -
LNN42_RS27770 (LNN42_27775) 23071..26217 + 3147 WP_004098958.1 Cu(+)/Ag(+) efflux RND transporter permease subunit SilA -
LNN42_RS27775 (LNN42_27780) 26304..26744 + 441 WP_000758228.1 DUF411 domain-containing protein -
LNN42_RS27780 (LNN42_27785) 26871..29318 + 2448 WP_004098955.1 Ag(+)-translocating P-type ATPase SilP -
LNN42_RS27785 (LNN42_27790) 29359..29556 + 198 WP_000843497.1 DUF2933 domain-containing protein -
LNN42_RS27790 (LNN42_27795) 29590..30327 - 738 WP_004118669.1 Murein DD-endopeptidase MepM VF
LNN42_RS27795 (LNN42_27800) 30616..31065 - 450 WP_001023257.1 copper resistance protein -
LNN42_RS27800 (LNN42_27805) 31299..33116 + 1818 WP_000925242.1 multicopper oxidase PcoA -
LNN42_RS27805 (LNN42_27810) 33122..34012 + 891 WP_001378118.1 copper resistance outer membrane transporter PcoB -
LNN42_RS27810 (LNN42_27815) 34052..34432 + 381 WP_000025662.1 copper resistance system metallochaperone PcoC -
LNN42_RS27815 (LNN42_27820) 34437..35366 + 930 WP_004118344.1 copper resistance inner membrane protein PcoD -
LNN42_RS27820 (LNN42_27825) 35421..36101 + 681 WP_001188930.1 Transcriptional activator protein CopR VF
LNN42_RS27825 (LNN42_27830) 36098..37498 + 1401 WP_004152084.1 copper resistance membrane spanning protein PcoS -
LNN42_RS27830 (LNN42_27835) 37715..38149 + 435 WP_004152085.1 copper resistance system metallochaperone PcoE -
LNN42_RS27835 (LNN42_27840) 38381..38560 - 180 WP_004152086.1 type II toxin-antitoxin system RelE/ParE family toxin -
LNN42_RS27840 (LNN42_27845) 38621..40241 - 1621 Protein_34 ISL3 family transposase ISEc38 Transposase
LNN42_RS27845 (LNN42_27850) 40303..40812 + 510 WP_031944101.1 aquaporin -
LNN42_RS27850 (LNN42_27855) 40862..41359 - 498 WP_004152091.1 GNAT family N-acetyltransferase -
LNN42_RS27855 (LNN42_27860) 41691..42017 + 327 WP_004152092.1 metalloregulator ArsR/SmtB family transcription factor -
LNN42_RS27860 (LNN42_27865) 42014..42727 + 714 WP_004152093.1 arsenical resistance protein ArsH -
LNN42_RS27865 (LNN42_27870) 42736..43281 + 546 WP_004182005.1 sigma-70 family RNA polymerase sigma factor -
LNN42_RS27870 (LNN42_27875) 43357..43719 + 363 WP_004152095.1 arsenic metallochaperone ArsD family protein -
LNN42_RS27875 (LNN42_27880) 43738..45494 + 1757 Protein_41 arsenical pump-driving ATPase -
LNN42_RS27880 (LNN42_27885) 45616..46152 + 537 WP_004152096.1 GNAT family N-acetyltransferase -
LNN42_RS27885 (LNN42_27890) 46185..46610 - 426 WP_004152097.1 glutaredoxin-dependent arsenate reductase -
LNN42_RS27890 (LNN42_27895) 46623..47912 - 1290 WP_004152098.1 arsenite efflux transporter membrane subunit ArsB -
LNN42_RS27895 (LNN42_27900) 47960..49711 - 1752 WP_004152099.1 Arsenical pump-driving ATPase VF
LNN42_RS27900 (LNN42_27905) 49729..50091 - 363 WP_004152100.1 arsenite efflux transporter metallochaperone ArsD -
LNN42_RS27905 (LNN42_27910) 50141..50491 - 351 WP_004152101.1 As(III)-sensing metalloregulatory transcriptional repressor ArsR -
LNN42_RS27910 (LNN42_27915) 50849..51118 + 270 WP_004152102.1 hypothetical protein -
LNN42_RS27915 (LNN42_27920) 51106..51681 + 576 WP_004152103.1 hypothetical protein -
LNN42_RS27920 (LNN42_27925) 51712..52206 + 495 WP_004152104.1 DNA-binding protein -
LNN42_RS27925 (LNN42_27930) 52250..52618 + 369 WP_004152105.1 hypothetical protein -
LNN42_RS27930 (LNN42_27935) 52652..52855 + 204 WP_004152106.1 HHA domain-containing protein -
LNN42_RS27935 (LNN42_27940) 52904..53161 + 258 WP_004152107.1 hypothetical protein -
LNN42_RS27940 (LNN42_27945) 53237..53491 + 255 WP_004152108.1 hypothetical protein -
LNN42_RS27945 (LNN42_27950) 53667..53933 + 267 WP_003026799.1 DUF1778 domain-containing protein Antitoxin Detail
LNN42_RS27950 (LNN42_27955) 53921..54403 + 483 WP_003026803.1 GNAT family N-acetyltransferase Toxin Detail
LNN42_RS27955 (LNN42_27960) 54604..56007 + 1404 WP_001567368.1 ISNCY family transposase ISKpn21 Transposase
LNN42_RS27960 (LNN42_27965) 56036..56668 - 633 WP_001567369.1 hypothetical protein -
LNN42_RS27965 (LNN42_27970) 56898..58244 + 1347 WP_020314316.1 ISNCY family transposase ISLad2 Transposase
LNN42_RS29130 58405..58536 + 132 WP_004218042.1 hypothetical protein -
LNN42_RS27970 (LNN42_27975) 58745..59910 - 1166 Protein_61 IS3 family transposase ISKpn38 Transposase
LNN42_RS27975 (LNN42_27980) 60087..61049 - 963 WP_004152113.1 zinc metalloprotease HtpX -
LNN42_RS27980 (LNN42_27985) 61036..61524 - 489 WP_004152114.1 phosphate-starvation-inducible PsiE family protein -
LNN42_RS27985 (LNN42_27990) 61639..61785 - 147 Protein_64 diguanylate cyclase -
LNN42_RS27990 (LNN42_27995) 62023..62220 - 198 WP_004152115.1 hypothetical protein -
LNN42_RS27995 (LNN42_28000) 62220..65015 - 2796 WP_004152116.1 ATP-dependent Clp protease ATP-binding subunit ClpC VF
LNN42_RS28000 (LNN42_28005) 65130..65699 - 570 WP_004152117.1 Spore protein SP21 VF
LNN42_RS28005 (LNN42_28010) 65734..66015 - 282 WP_004152118.1 helix-turn-helix domain-containing protein -
LNN42_RS28010 (LNN42_28015) 66259..66522 - 264 WP_004118208.1 hypothetical protein -
LNN42_RS28015 (LNN42_28020) 66537..66800 + 264 WP_004118209.1 transposase -
LNN42_RS28020 (LNN42_28025) 66745..66861 + 117 Protein_71 transposase domain-containing protein -
LNN42_RS28025 (LNN42_28030) 67046..67743 + 698 WP_223174644.1 IS1 family transposase IS1X2 Transposase
LNN42_RS28030 (LNN42_28035) 68002..68982 + 981 WP_000019473.1 IS5 family transposase ISKpn26 Transposase
LNN42_RS28035 (LNN42_28040) 69564..70083 - 520 Protein_74 IS5 family transposase ISPst7 Transposase
LNN42_RS28040 (LNN42_28045) 70191..71060 - 870 WP_004152692.1 HTH-type transcriptional activator CmpR VF
LNN42_RS28045 (LNN42_28050) 71054..72064 - 1011 WP_004152693.1 phosphonate dehydrogenase PtxD -
LNN42_RS28050 (LNN42_28055) 72073..72900 - 828 WP_004152694.1 phosphonate ABC transporter, permease protein PhnE -
LNN42_RS28055 (LNN42_28060) 72909..73772 - 864 WP_004152695.1 phosphate/phosphite/phosphonate ABC transporter substrate-binding protein -
LNN42_RS28060 (LNN42_28065) 73769..74596 - 828 WP_004153729.1 Glutamine transport ATP-binding protein GlnQ VF
LNN42_RS28065 (LNN42_28070) 74938..75246 + 309 Protein_80 IS5 family transposase ISThi1 Transposase
LNN42_RS28070 (LNN42_28075) 75452..76156 - 705 WP_004217321.1 IS6 family transposase IS26 Transposase
LNN42_RS28075 (LNN42_28080) 76147..76737 + 591 WP_004197543.1 recombinase family protein -
LNN42_RS28080 (LNN42_28085) 76767..77633 - 867 WP_004197546.1 Beta-lactamase ARG
LNN42_RS28085 (LNN42_28090) 77795..78994 + 1200 WP_004197531.1 cellulase family glycosylhydrolase -
LNN42_RS28090 (LNN42_28095) 79186..79377 - 192 Protein_85 methyltransferase -
LNN42_RS28095 (LNN42_28100) 80013..80993 + 981 WP_000019473.1 IS5 family transposase ISKpn26 Transposase
LNN42_RS28100 (LNN42_28105) 81329..82606 - 1278 WP_004197540.1 Y-family DNA polymerase -
LNN42_RS28105 (LNN42_28110) 82612..83040 - 429 WP_004197551.1 S24 family peptidase -
LNN42_RS28110 (LNN42_28115) 83136..83408 - 273 WP_004197545.1 helix-turn-helix transcriptional regulator -
LNN42_RS28115 (LNN42_28120) 83533..84293 + 761 WP_085947932.1 IS5 family transposase ISKpn12 Transposase
LNN42_RS28120 (LNN42_28125) 85185..85370 + 186 WP_004197549.1 hypothetical protein -
LNN42_RS28125 (LNN42_28130) 85436..85918 - 483 Protein_92 IS3 family transposase ISKpn11 Transposase
LNN42_RS28130 (LNN42_28135) 85987..87495 - 1509 WP_001189111.1 group II intron reverse transcriptase/maturase -
LNN42_RS28135 (LNN42_28140) 88159..88844 - 686 Protein_94 IS3 family transposase ISKpn11 Transposase
LNN42_RS28140 (LNN42_28145) 88930..89190 - 261 Protein_95 hypothetical protein -
LNN42_RS28145 (LNN42_28150) 89203..90063 - 861 WP_000557452.1 SPBc2 prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD ARG
LNN42_RS28150 (LNN42_28155) 90205..91065 - 861 WP_000027057.1 Beta-lactamase TEM ARG
LNN42_RS28155 (LNN42_28160) 91248..91805 - 558 WP_001235713.1 Tn3 family transposase TnpR_Tn3 Transposase
LNN42_RS28160 (LNN42_28165) 91969..92175 + 207 Protein_99 Tn3 family transposase TnpA_Tn3 Transposase
LNN42_RS28165 (LNN42_28170) 92369..93631 + 1263 WP_000608644.1 IS1380 family transposase ISEcp1 Transposase
LNN42_RS28170 (LNN42_28175) 93838..94818 - 981 WP_000019473.1 IS5 family transposase ISKpn26 Transposase
LNN42_RS28175 (LNN42_28180) 94889..95122 - 234 Protein_102 PIN domain-containing protein -
LNN42_RS28180 (LNN42_28185) 95283..95876 - 594 WP_023280883.1 fertility inhibition protein FinO -
LNN42_RS28185 (LNN42_28190) 96033..96758 - 726 WP_031944112.1 type-F conjugative transfer system pilin acetylase TraX -
LNN42_RS28190 (LNN42_28195) 96802..102063 - 5262 WP_031944111.1 Multifunctional conjugation protein TraI Relaxase
LNN42_RS28195 (LNN42_28200) 102063..104375 - 2313 WP_031944110.1 type IV conjugative transfer system coupling protein TraD -
LNN42_RS28200 (LNN42_28205) 104735..105466 - 732 WP_004152629.1 conjugal transfer complement resistance protein TraT -
LNN42_RS28205 (LNN42_28210) 105656..106183 - 528 WP_004153030.1 hypothetical protein -
LNN42_RS28210 (LNN42_28215) 106189..109038 - 2850 WP_004178054.1 conjugal transfer mating-pair stabilization protein TraG -
LNN42_RS28215 (LNN42_28220) 109038..110408 - 1371 WP_004178055.1 conjugal transfer pilus assembly protein TraH -
LNN42_RS28220 (LNN42_28225) 110395..110823 - 429 WP_004152689.1 hypothetical protein -
LNN42_RS28225 (LNN42_28230) 110816..111388 - 573 WP_004152688.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
LNN42_RS28230 (LNN42_28235) 111360..111599 - 240 WP_004152687.1 type-F conjugative transfer system pilin chaperone TraQ -
LNN42_RS28235 (LNN42_28240) 111610..112362 - 753 WP_004152686.1 type-F conjugative transfer system pilin assembly protein TraF -
LNN42_RS28240 (LNN42_28245) 112383..112709 - 327 WP_004152685.1 hypothetical protein -
LNN42_RS28245 (LNN42_28250) 112937..113173 - 237 WP_004152683.1 conjugal transfer protein TrbE -
LNN42_RS28250 (LNN42_28255) 113205..115160 - 1956 WP_004153093.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
LNN42_RS28255 (LNN42_28260) 115208..115846 - 639 WP_004152682.1 type-F conjugative transfer system pilin assembly protein TrbC -
LNN42_RS28260 (LNN42_28265) 115859..116818 - 960 WP_015065634.1 conjugal transfer pilus assembly protein TraU -
LNN42_RS28265 (LNN42_28270) 116862..117488 - 627 WP_004152590.1 type-F conjugative transfer system protein TraW -
LNN42_RS28270 (LNN42_28275) 117488..117877 - 390 WP_004152591.1 type-F conjugative transfer system protein TrbI -
LNN42_RS28275 (LNN42_28280) 117877..120516 - 2640 WP_004152592.1 type IV secretion system protein TraC -
LNN42_RS28280 (LNN42_28285) 120588..120986 - 399 WP_004153071.1 hypothetical protein -
LNN42_RS28285 (LNN42_28290) 121282..121686 - 405 WP_031944109.1 hypothetical protein -
LNN42_RS28290 (LNN42_28295) 121753..122070 - 318 WP_004152595.1 hypothetical protein -
LNN42_RS28295 (LNN42_28300) 122071..122289 - 219 WP_004171484.1 hypothetical protein -
LNN42_RS28300 (LNN42_28305) 122313..122603 - 291 WP_004152596.1 hypothetical protein -
LNN42_RS28305 (LNN42_28310) 122608..123018 - 411 WP_004152597.1 lipase chaperone -
LNN42_RS28310 (LNN42_28315) 123150..123719 - 570 WP_004152598.1 type IV conjugative transfer system lipoprotein TraV -
LNN42_RS28315 (LNN42_28320) 123742..124338 - 597 WP_004152599.1 conjugal transfer pilus-stabilizing protein TraP -
LNN42_RS28320 (LNN42_28325) 124331..125755 - 1425 WP_004152600.1 F-type conjugal transfer pilus assembly protein TraB -
LNN42_RS28325 (LNN42_28330) 125755..126495 - 741 WP_004152601.1 type-F conjugative transfer system secretin TraK -
LNN42_RS28330 (LNN42_28335) 126482..127048 - 567 WP_004152602.1 type IV conjugative transfer system protein TraE -
LNN42_RS28335 (LNN42_28340) 127068..127373 - 306 WP_004178059.1 type IV conjugative transfer system protein TraL -
LNN42_RS28340 (LNN42_28345) 127387..127755 - 369 WP_004178060.1 type IV conjugative transfer system pilin TraA -
LNN42_RS28345 (LNN42_28350) 127809..128180 - 372 WP_004208838.1 TraY domain-containing protein -
LNN42_RS28350 (LNN42_28355) 128264..128959 - 696 WP_004178061.1 transcriptional regulator TraJ family protein -
LNN42_RS28355 (LNN42_28360) 129173..129565 - 393 WP_004178062.1 conjugal transfer relaxosome DNA-binding protein TraM -
LNN42_RS28360 (LNN42_28365) 129999..130484 + 486 WP_004178063.1 hypothetical protein VF
LNN42_RS28365 (LNN42_28370) 130517..130846 - 330 WP_011977736.1 DUF5983 family protein -
LNN42_RS28370 (LNN42_28375) 130879..131700 - 822 WP_004178064.1 DUF932 domain-containing protein -
LNN42_RS28375 (LNN42_28380) 132007..132975 + 969 WP_073970534.1 IS5 family transposase IS903 Transposase
LNN42_RS28380 (LNN42_28385) 133600..134013 - 414 WP_004152722.1 helix-turn-helix domain-containing protein -
LNN42_RS28385 (LNN42_28390) 134014..134292 - 279 WP_004152721.1 helix-turn-helix transcriptional regulator -
LNN42_RS28390 (LNN42_28395) 134282..134602 - 321 WP_004152720.1 type II toxin-antitoxin system RelE/ParE family toxin -
LNN42_RS28395 (LNN42_28400) 134683..134907 - 225 WP_004152719.1 hypothetical protein -
LNN42_RS28400 (LNN42_28405) 134918..135130 - 213 WP_004152718.1 hypothetical protein -
LNN42_RS28405 (LNN42_28410) 135191..135547 - 357 WP_004152717.1 hypothetical protein -
LNN42_RS28410 (LNN42_28415) 136183..136533 - 351 WP_004152758.1 hypothetical protein -
LNN42_RS28415 (LNN42_28420) 136530..136802 - 273 WP_004152759.1 hypothetical protein -
LNN42_RS28420 (LNN42_28425) 137502..137624 - 123 WP_085842394.1 Hok/Gef family protein -
LNN42_RS28425 (LNN42_28430) 137569..137721 - 153 Protein_152 DUF5431 family protein -
LNN42_RS28430 (LNN42_28435) 137891..138265 - 375 WP_004152638.1 hypothetical protein -
LNN42_RS28435 (LNN42_28440) 138321..138647 - 327 WP_004152639.1 hypothetical protein -
LNN42_RS28440 (LNN42_28445) 138644..139372 - 729 WP_004152640.1 plasmid SOS inhibition protein A -
LNN42_RS28445 (LNN42_28450) 139369..139800 - 432 WP_004152641.1 conjugation system SOS inhibitor PsiB -
LNN42_RS28450 (LNN42_28455) 139845..141903 - 2059 Protein_157 ParB/RepB/Spo0J family partition protein -
LNN42_RS28455 (LNN42_28460) 141973..142221 - 249 WP_004152643.1 DUF905 domain-containing protein -
LNN42_RS28460 (LNN42_28465) 142270..142812 - 543 WP_004152644.1 single-stranded DNA-binding protein -
LNN42_RS28465 (LNN42_28470) 143588..144151 - 564 WP_004152645.1 methyltransferase -
LNN42_RS28470 (LNN42_28475) 144199..145554 - 1356 WP_004178068.1 DUF3560 domain-containing protein -
LNN42_RS28475 (LNN42_28480) 145606..145836 - 231 WP_004198570.1 hypothetical protein -
LNN42_RS28480 (LNN42_28485) 145928..146155 - 228 WP_004178072.1 hypothetical protein -
LNN42_RS28485 (LNN42_28490) 146937..147254 - 318 WP_004118473.1 hypothetical protein -
LNN42_RS28490 (LNN42_28495) 147289..147543 - 255 WP_004152754.1 DNA polymerase III subunit theta -
LNN42_RS28495 (LNN42_28500) 147780..148205 - 426 WP_004118478.1 antirestriction protein -
LNN42_RS28500 (LNN42_28505) 148726..148956 - 231 WP_004152753.1 hypothetical protein -
LNN42_RS28505 (LNN42_28510) 149190..150677 - 1488 WP_004178082.1 group II intron reverse transcriptase/maturase -
LNN42_RS28510 (LNN42_28515) 151080..151505 + 426 WP_004178083.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
LNN42_RS28515 (LNN42_28520) 151505..152776 + 1272 WP_004152715.1 Y-family DNA polymerase -
LNN42_RS28520 (LNN42_28525) 152915..153070 + 156 WP_001776126.1 hypothetical protein -
LNN42_RS28525 (LNN42_28530) 153093..154291 - 1199 Protein_172 IS200-IS605 family transposase IS609 Transposase
LNN42_RS28530 (LNN42_28535) 155556..156527 - 972 WP_004152062.1 ParB/RepB/Spo0J family plasmid partition protein -
LNN42_RS28535 (LNN42_28540) 156527..157693 - 1167 WP_000523813.1 Sporulation initiation inhibitor protein Soj VF

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance