MGE detailed information
MGE type: Conjugative plasmid MGE length: 146039 bp
Accession: NZ_CP085070 Location: 1..146039 Organism: Escherichia coli strain P27_L1_05.20 Replicon: plasmid pNDM_P27_L1_05.20
Accession: NZ_CP085070 Location: 1..146039 Organism: Escherichia coli strain P27_L1_05.20 Replicon: plasmid pNDM_P27_L1_05.20
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LH371_RS23975 (1) | 1..978 | + | 978 | WP_000361612.1 | RepB family plasmid replication initiator protein | - |
| LH371_RS23980 (1263) | 1263..2003 | - | 741 | WP_001066942.1 | tyrosine-type recombinase/integrase | - |
| LH371_RS23985 (2124) | 2124..2306 | - | 183 | WP_042065278.1 | hypothetical protein | - |
| LH371_RS23990 (2373) | 2373..2662 | - | 290 | Protein_3 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| LH371_RS23995 (2649) | 2649..2917 | - | 269 | Protein_4 | type II toxin-antitoxin system ParD family antitoxin | - |
| LH371_RS24000 (3449) | 3449..4618 | + | 1170 | WP_001072355.1 | hypothetical protein | - |
| LH371_RS24005 (4651) | 4651..4779 | + | 129 | Protein_6 | IS481 family transposase | - |
| LH371_RS24010 (4904) | 4904..5107 | - | 204 | Protein_7 | hypothetical protein | - |
| LH371_RS24015 (5213) | 5213..5488 | - | 276 | WP_000421272.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| LH371_RS24020 (5488) | 5488..5772 | - | 285 | WP_001387467.1 | ribbon-helix-helix domain-containing protein | Antitoxin Detail |
| LH371_RS24025 (6377) | 6377..7129 | + | 753 | WP_000562172.1 | IclR family transcriptional regulator | - |
| LH371_RS24030 (7175) | 7175..8140 | - | 966 | WP_001022265.1 | 2-keto-3-deoxygluconate transporter | - |
| LH371_RS24035 (8173) | 8173..8553 | - | 381 | WP_000710783.1 | Rid family detoxifying hydrolase | - |
| LH371_RS24040 (8578) | 8578..9207 | - | 630 | WP_231528705.1 | dihydrodipicolinate synthase family protein | - |
| LH371_RS24045 (9251) | 9251..9883 | + | 633 | Protein_14 | sugar ABC transporter permease | - |
| LH371_RS24050 (9873) | 9873..10760 | + | 888 | WP_001271561.1 | carbohydrate ABC transporter permease | - |
| LH371_RS24055 (10771) | 10771..11595 | + | 825 | WP_000922702.1 | phosphodiesterase | - |
| LH371_RS24060 (11601) | 11601..12674 | + | 1074 | WP_033549814.1 | sn-glycerol-3-phosphate import ATP-binding protein UgpC | VF |
| LH371_RS24065 (12667) | 12667..13977 | + | 1311 | WP_000476108.1 | ABC transporter substrate-binding protein | - |
| LH371_RS24070 (14036) | 14036..14344 | - | 309 | Protein_19 | IS4 family transposase ISEc13 | Transposase |
| LH371_RS24075 (14421) | 14421..14594 | - | 174 | WP_000338295.1 | Tn3 family transposase ISPsy39 | Transposase |
| LH371_RS24080 (14676) | 14676..15156 | - | 481 | Protein_21 | IS3 family transposase IS629 | Transposase |
| LH371_RS24085 (15240) | 15240..16748 | - | 1509 | WP_001189123.1 | group II intron reverse transcriptase/maturase | - |
| LH371_RS24090 (17421) | 17421..18142 | - | 722 | Protein_23 | IS3 family transposase IS629 | Transposase |
| LH371_RS24095 (18167) | 18167..18871 | + | 705 | WP_001067834.1 | IS6 family transposase IS26 | Transposase |
| LH371_RS24100 (18929) | 18929..19459 | - | 531 | Protein_25 | histidine-type phosphatase | - |
| LH371_RS24105 (19581) | 19581..20066 | - | 486 | WP_000874189.1 | hypothetical protein | - |
| LH371_RS24110 (20091) | 20091..20576 | - | 486 | WP_001267177.1 | TlpA disulfide reductase family protein | - |
| LH371_RS24115 (20563) | 20563..21258 | - | 696 | WP_000117262.1 | Lipoprotein-releasing system ATP-binding protein LolD | VF |
| LH371_RS24120 (21263) | 21263..22393 | - | 1131 | WP_000729220.1 | ABC transporter permease | - |
| LH371_RS24125 (22383) | 22383..23666 | - | 1284 | WP_000964653.1 | ABC transporter permease | - |
| LH371_RS24130 (23669) | 23669..25048 | - | 1380 | WP_000119836.1 | Fe-S-containing protein | - |
| LH371_RS24135 (25152) | 25152..25679 | - | 528 | WP_000178050.1 | iron transporter | - |
| LH371_RS24140 (25720) | 25720..27606 | - | 1887 | WP_000118029.1 | FTR1 family protein | - |
| LH371_RS24145 (27953) | 27953..28714 | - | 762 | WP_001225378.1 | Na(+)-translocating NADH-quinone reductase subunit C | - |
| LH371_RS24150 (28951) | 28951..29457 | - | 507 | WP_000949452.1 | protein disulfide oxidoreductase | - |
| LH371_RS24155 (29447) | 29447..29617 | - | 171 | Protein_36 | DsbA family protein | - |
| LH371_RS24160 (29755) | 29755..29868 | - | 114 | Protein_37 | IS6 family transposase | - |
| LH371_RS24165 (29959) | 29959..30810 | + | 852 | Protein_38 | IS4 family transposase IS10R | Transposase |
| LH371_RS24170 (30863) | 30863..31567 | - | 705 | WP_001067834.1 | IS6 family transposase IS26 | Transposase |
| LH371_RS24175 (31632) | 31632..32555 | - | 924 | Protein_40 | IS91 family transposase ISAzo26 | Transposase |
| LH371_RS24180 (32700) | 32700..33197 | + | 498 | WP_001083725.1 | Dihydrofolate reductase | ARG |
| LH371_RS24185 (33309) | 33309..33599 | + | 291 | WP_001336345.1 | DUF1010 domain-containing protein | - |
| LH371_RS24190 (33605) | 33605..34443 | + | 839 | Protein_43 | Streptomycin 3''-adenylyltransferase | ARG |
| LH371_RS24195 (34560) | 34560..34907 | + | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| LH371_RS24200 (34901) | 34901..35740 | + | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| LH371_RS24205 (36145) | 36145..37686 | + | 1542 | WP_000050481.1 | IS91 family transposase ISVsa3 | Transposase |
| LH371_RS24210 (37999) | 37999..38373 | + | 375 | Protein_47 | protein-disulfide reductase DsbD family protein | - |
| LH371_RS24215 (38473) | 38473..39030 | + | 558 | Protein_48 | twin-arginine translocation (TAT) pathway signal sequence domain protein | - |
| LH371_RS24220 (39041) | 39041..39679 | - | 639 | WP_004201168.1 | phosphoribosylanthranilate isomerase | - |
| LH371_RS24225 (39684) | 39684..40049 | - | 366 | WP_004201167.1 | bleomycin binding protein Ble-MBL | - |
| LH371_RS24230 (40053) | 40053..40865 | - | 813 | WP_023408309.1 | Metallo-beta-lactamase type 2 | ARG |
| LH371_RS24235 (40966) | 40966..41259 | - | 294 | Protein_52 | IS30 family transposase | - |
| LH371_RS24240 (41424) | 41424..42128 | + | 705 | WP_001067834.1 | IS6 family transposase IS26 | Transposase |
| LH371_RS24245 (42322) | 42322..42672 | - | 351 | Protein_54 | 60 kDa chaperonin | VF |
| LH371_RS24250 (42735) | 42735..43283 | + | 549 | WP_014342204.1 | cation:proton antiporter | - |
| LH371_RS24255 (43364) | 43364..44119 | - | 756 | WP_012372818.1 | 16S rRNA (guanine(1405)-N(7))-methyltransferase | ARG |
| LH371_RS24260 (44289) | 44289..45149 | - | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| LH371_RS24265 (45332) | 45332..45889 | - | 558 | WP_001235713.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| LH371_RS24270 (46191) | 46191..46955 | + | 765 | WP_001389365.1 | IS6 family transposase IS6100 | Transposase |
| LH371_RS24275 (47448) | 47448..48032 | - | 585 | WP_001137892.1 | macrolide-binding transcriptional repressor MphR(A) | - |
| LH371_RS24280 (48032) | 48032..49270 | - | 1239 | WP_000004159.1 | macrolide resistance MFS transporter Mrx(A) | - |
| LH371_RS24285 (49267) | 49267..50181 | - | 915 | WP_023063803.1 | hypothetical protein | ARG |
| LH371_RS24290 (50303) | 50303..51007 | - | 705 | WP_001067834.1 | IS6 family transposase IS26 | Transposase |
| LH371_RS24295 (51142) | 51142..51237 | + | 96 | WP_013362819.1 | 23S rRNA methyltransferase attenuation leader peptide | - |
| LH371_RS24300 (51363) | 51363..52100 | + | 738 | WP_013362818.1 | rRNA adenine N-6-methyltransferase | ARG |
| LH371_RS24305 (52730) | 52730..53179 | + | 450 | WP_013362817.1 | hypothetical protein | - |
| LH371_RS24310 (53140) | 53140..53481 | + | 342 | WP_023909256.1 | 60 kDa chaperonin 2 | VF |
| LH371_RS24315 (53756) | 53756..55147 | + | 1392 | Protein_68 | IS91 family transposase ISVsa3 | Transposase |
| LH371_RS24320 (55201) | 55201..55905 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| LH371_RS24325 (55971) | 55971..56516 | + | 546 | Protein_70 | Tn3 family transposase TnpA_Tn3 | Transposase |
| LH371_RS24330 (56552) | 56552..56967 | - | 416 | Protein_71 | IS1-like element IS1B family transposase | - |
| LH371_RS24335 (57216) | 57216..57617 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| LH371_RS24340 (57550) | 57550..57807 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| LH371_RS24345 (57900) | 57900..58553 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| LH371_RS24350 (59492) | 59492..60349 | - | 858 | WP_060591631.1 | incFII family plasmid replication initiator RepA | - |
| LH371_RS24355 (60342) | 60342..60416 | - | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| LH371_RS24360 (60654) | 60654..60908 | - | 255 | WP_000083830.1 | replication regulatory protein RepA | - |
| LH371_RS24365 (61148) | 61148..61738 | - | 591 | WP_000766807.1 | DUF2726 domain-containing protein | - |
| LH371_RS24370 (61776) | 61776..61985 | - | 210 | WP_001298565.1 | hemolysin expression modulator Hha | - |
| LH371_RS24375 (62031) | 62031..62492 | - | 462 | WP_001233838.1 | thermonuclease family protein | - |
| LH371_RS24380 (62737) | 62737..62949 | - | 213 | WP_001309245.1 | ANR family transcriptional regulator | - |
| LH371_RS24385 (63078) | 63078..63638 | - | 561 | WP_000139323.1 | fertility inhibition protein FinO | - |
| LH371_RS24390 (63741) | 63741..64601 | - | 861 | WP_000704523.1 | putative protein YcjY | VF |
| LH371_RS24395 (64660) | 64660..65406 | - | 747 | WP_000205725.1 | conjugal transfer pilus acetylase TraX | - |
| LH371_RS24400 (65426) | 65426..70696 | - | 5271 | WP_000948354.1 | Multifunctional conjugation protein TraI | Relaxase |
| LH371_RS24405 (70696) | 70696..72984 | - | 2289 | WP_125097878.1 | Coupling protein TraD | VF |
| LH371_RS24410 (73035) | 73035..73772 | - | 738 | WP_000199905.1 | hypothetical protein | - |
| LH371_RS24415 (73975) | 73975..74706 | - | 732 | WP_000782451.1 | conjugal transfer complement resistance protein TraT | - |
| LH371_RS24420 (74755) | 74755..75240 | - | 486 | WP_000605870.1 | hypothetical protein | - |
| LH371_RS24425 (75256) | 75256..78078 | - | 2823 | WP_001007039.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| LH371_RS24430 (78075) | 78075..79448 | - | 1374 | WP_000944331.1 | conjugal transfer pilus assembly protein TraH | - |
| LH371_RS24435 (79435) | 79435..79827 | - | 393 | WP_000660699.1 | F-type conjugal transfer protein TrbF | - |
| LH371_RS24440 (79808) | 79808..80155 | - | 348 | WP_001309242.1 | P-type conjugative transfer protein TrbJ | - |
| LH371_RS24445 (80085) | 80085..80630 | - | 546 | WP_000059831.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| LH371_RS24450 (80617) | 80617..80901 | - | 285 | WP_000624194.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| LH371_RS24455 (81020) | 81020..81364 | - | 345 | WP_000556796.1 | conjugal transfer protein TrbA | - |
| LH371_RS24460 (81378) | 81378..82121 | - | 744 | WP_001030371.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| LH371_RS24465 (82114) | 82114..82371 | - | 258 | WP_000864353.1 | conjugal transfer protein TrbE | - |
| LH371_RS24470 (82473) | 82473..83219 | - | 747 | WP_001016257.1 | IS21 family transposase ISEc12 | Transposase |
| LH371_RS24475 (83234) | 83234..84775 | - | 1542 | WP_001518966.1 | IS21 family transposase ISEc12 | Transposase |
| LH371_RS24480 (84984) | 84984..86834 | - | 1851 | WP_000821856.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| LH371_RS24485 (86831) | 86831..87469 | - | 639 | WP_046960657.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| LH371_RS24490 (87478) | 87478..88470 | - | 993 | WP_001553833.1 | conjugal transfer pilus assembly protein TraU | - |
| LH371_RS24495 (88467) | 88467..89099 | - | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| LH371_RS24500 (89096) | 89096..89482 | - | 387 | WP_000099690.1 | type-F conjugative transfer system protein TrbI | - |
| LH371_RS24505 (89479) | 89479..92106 | - | 2628 | WP_001064264.1 | type IV secretion system protein TraC | - |
| LH371_RS24510 (92266) | 92266..92487 | - | 222 | WP_001278692.1 | conjugal transfer protein TraR | - |
| LH371_RS24515 (92622) | 92622..93137 | - | 516 | WP_000809832.1 | type IV conjugative transfer system lipoprotein TraV | - |
| LH371_RS24520 (93134) | 93134..93385 | - | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
| LH371_RS24525 (93378) | 93378..93698 | - | 321 | Protein_110 | conjugal transfer protein TrbD | - |
| LH371_RS24530 (93685) | 93685..94275 | - | 591 | WP_000002787.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| LH371_RS24535 (94265) | 94265..95692 | - | 1428 | WP_001553836.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| LH371_RS24540 (95692) | 95692..96420 | - | 729 | WP_001230813.1 | type-F conjugative transfer system secretin TraK | - |
| LH371_RS24545 (96407) | 96407..96973 | - | 567 | WP_000399790.1 | type IV conjugative transfer system protein TraE | - |
| LH371_RS24550 (96995) | 96995..97306 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| LH371_RS24555 (97321) | 97321..97686 | - | 366 | WP_000340282.1 | type IV conjugative transfer system pilin TraA | - |
| LH371_RS24560 (97729) | 97729..97944 | - | 216 | WP_001352842.1 | conjugal transfer relaxosome protein TraY | - |
| LH371_RS24565 (98080) | 98080..98727 | - | 648 | WP_000332520.1 | conjugal transfer transcriptional regulator TraJ | - |
| LH371_RS24570 (98918) | 98918..99301 | - | 384 | WP_001063020.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| LH371_RS24575 (99671) | 99671..100243 | + | 573 | WP_000949660.1 | hypothetical protein | VF |
| LH371_RS24580 (100539) | 100539..101360 | - | 822 | WP_001234465.1 | DUF932 domain-containing protein | - |
| LH371_RS24585 (101479) | 101479..101766 | - | 288 | WP_000107242.1 | hypothetical protein | - |
| LH371_RS24590 (101791) | 101791..101997 | - | 207 | WP_000275854.1 | hypothetical protein | - |
| LH371_RS24595 (102067) | 102067..102364 | + | 298 | Protein_124 | hypothetical protein | - |
| LH371_RS24600 (102665) | 102665..102790 | - | 126 | WP_096937776.1 | type I toxin-antitoxin system Hok family toxin | - |
| LH371_RS24605 (102732) | 102732..102881 | - | 150 | Protein_126 | DUF5431 family protein | - |
| - (104343) | 104343..104533 | - | 191 | NuclAT_0 | - | - |
| - (104343) | 104343..104533 | - | 191 | NuclAT_0 | - | - |
| - (104343) | 104343..104533 | - | 191 | NuclAT_0 | - | - |
| - (104343) | 104343..104533 | - | 191 | NuclAT_0 | - | - |
| LH371_RS24615 (104502) | 104502..104607 | - | 106 | Protein_128 | plasmid SOS inhibition protein A | - |
| LH371_RS24620 (104762) | 104762..105079 | + | 318 | Protein_129 | IS110 family transposase | - |
| LH371_RS24625 (105368) | 105368..105619 | - | 252 | Protein_130 | iron-containing alcohol dehydrogenase | - |
| LH371_RS24630 (105704) | 105704..106216 | - | 513 | WP_223350513.1 | potassium channel family protein | - |
| LH371_RS24635 (106343) | 106343..107036 | - | 694 | Protein_132 | IS1 family transposase IS1A | Transposase |
| LH371_RS24640 (107093) | 107093..107197 | + | 105 | Protein_133 | thiosulfate reductase cytochrome B subunit | - |
| LH371_RS24645 (107443) | 107443..108837 | - | 1395 | WP_001037799.1 | carbohydrate porin | - |
| LH371_RS24650 (109032) | 109032..110465 | - | 1434 | WP_024170639.1 | glycoside hydrolase family 32 protein | - |
| LH371_RS24655 (110462) | 110462..111739 | - | 1278 | WP_001083369.1 | MFS transporter | - |
| LH371_RS24660 (111802) | 111802..113928 | - | 2127 | WP_000253905.1 | alpha-galactosidase | - |
| LH371_RS24665 (114024) | 114024..115034 | - | 1011 | WP_000053332.1 | substrate-binding domain-containing protein | - |
| LH371_RS24670 (115192) | 115192..115950 | - | 759 | Protein_139 | site-specific integrase | - |
| LH371_RS24675 (116041) | 116041..117269 | + | 1229 | WP_152924612.1 | IS3 family transposase IS2 | Transposase |
| LH371_RS24680 (117254) | 117254..117823 | + | 570 | WP_089634947.1 | hypothetical protein | - |
| LH371_RS24685 (118754) | 118754..119017 | - | 264 | WP_071781663.1 | hypothetical protein | - |
| LH371_RS24690 (118924) | 118924..119142 | - | 219 | WP_001496291.1 | hypothetical protein | - |
| LH371_RS24695 (119168) | 119168..119731 | - | 564 | WP_001348621.1 | class I SAM-dependent methyltransferase | - |
| LH371_RS24700 (119779) | 119779..121140 | - | 1362 | WP_000170714.1 | DUF3560 domain-containing protein | - |
| LH371_RS24705 (121192) | 121192..121422 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| LH371_RS24710 (122457) | 122457..122648 | - | 192 | WP_001027516.1 | hypothetical protein | - |
| LH371_RS24715 (122645) | 122645..123067 | - | 423 | WP_000271753.1 | DUF1380 family protein | - |
| LH371_RS24720 (123114) | 123114..123539 | - | 426 | WP_001198928.1 | antirestriction protein | - |
| LH371_RS24725 (123956) | 123956..124732 | - | 777 | WP_001753849.1 | hypothetical protein | - |
| LH371_RS24730 (124783) | 124783..125301 | - | 519 | WP_123325260.1 | DUF1380 family protein | - |
| LH371_RS24735 (125231) | 125231..125452 | - | 222 | WP_001104873.1 | hypothetical protein | - |
| LH371_RS24740 (125453) | 125453..126136 | - | 684 | WP_000086185.1 | DNA methylase | - |
| LH371_RS24745 (126213) | 126213..126524 | - | 312 | WP_011254640.1 | hypothetical protein | - |
| LH371_RS24750 (126521) | 126521..127423 | - | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| LH371_RS24755 (128290) | 128290..129261 | - | 972 | WP_000817036.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| LH371_RS24760 (129261) | 129261..130427 | - | 1167 | WP_000772446.1 | Sporulation initiation inhibitor protein Soj | VF |
| LH371_RS24765 (131015) | 131015..131770 | - | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| LH371_RS24770 (132544) | 132544..133350 | - | 807 | WP_000016982.1 | site-specific integrase | - |
| LH371_RS24775 (133351) | 133351..133656 | - | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| LH371_RS24780 (133658) | 133658..133876 | - | 219 | WP_000813634.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| LH371_RS24785 (134510) | 134510..134707 | + | 198 | WP_000215657.1 | hypothetical protein | - |
| LH371_RS24790 (134704) | 134704..134988 | - | 285 | WP_000642771.1 | hypothetical protein | - |
| LH371_RS24795 (135008) | 135008..136141 | - | 1134 | WP_000545983.1 | DUF3800 domain-containing protein | - |
| LH371_RS24800 (136404) | 136404..139523 | - | 3120 | WP_001553851.1 | hypothetical protein | - |
| LH371_RS24805 (139830) | 139830..140060 | + | 231 | WP_001261287.1 | type II toxin-antitoxin system VapB family antitoxin | - |
| LH371_RS24810 (140057) | 140057..140473 | + | 417 | WP_001044768.1 | type II toxin-antitoxin system VapC family toxin | - |
| LH371_RS24815 (140635) | 140635..142773 | - | 2139 | WP_000350635.1 | AAA family ATPase | - |
| LH371_RS24825 (144314) | 144314..145284 | - | 971 | Protein_170 | hypothetical protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|