MGE detailed information
MGE type: Conjugative plasmid MGE length: 133958 bp
Accession: NZ_CP085064 Location: 1..133958 Organism: Escherichia coli strain P31_YH1_02.21 Replicon: plasmid pNDM_P31_YH1_02.21
Accession: NZ_CP085064 Location: 1..133958 Organism: Escherichia coli strain P31_YH1_02.21 Replicon: plasmid pNDM_P31_YH1_02.21
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LH370_RS24935 (1) | 1..978 | + | 978 | WP_000361612.1 | RepB family plasmid replication initiator protein | - |
| LH370_RS24940 (1263) | 1263..2003 | - | 741 | WP_001066942.1 | tyrosine-type recombinase/integrase | - |
| LH370_RS24945 (2124) | 2124..2306 | - | 183 | WP_042065278.1 | hypothetical protein | - |
| LH370_RS24950 (2373) | 2373..2662 | - | 290 | Protein_3 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| LH370_RS24955 (2649) | 2649..2917 | - | 269 | Protein_4 | type II toxin-antitoxin system ParD family antitoxin | - |
| LH370_RS24960 (3449) | 3449..4618 | + | 1170 | WP_001072355.1 | hypothetical protein | - |
| LH370_RS24965 (4651) | 4651..4779 | + | 129 | Protein_6 | IS481 family transposase | - |
| LH370_RS24970 (4904) | 4904..5107 | - | 204 | Protein_7 | hypothetical protein | - |
| LH370_RS24975 (5213) | 5213..5488 | - | 276 | WP_000421272.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| LH370_RS24980 (5488) | 5488..5772 | - | 285 | WP_001387467.1 | ribbon-helix-helix domain-containing protein | Antitoxin Detail |
| LH370_RS24985 (6377) | 6377..7129 | + | 753 | WP_000562172.1 | IclR family transcriptional regulator | - |
| LH370_RS24990 (7175) | 7175..8140 | - | 966 | WP_001022265.1 | 2-keto-3-deoxygluconate transporter | - |
| LH370_RS24995 (8173) | 8173..8553 | - | 381 | WP_000710783.1 | Rid family detoxifying hydrolase | - |
| LH370_RS25000 (8578) | 8578..9207 | - | 630 | WP_231528705.1 | dihydrodipicolinate synthase family protein | - |
| LH370_RS25005 (9251) | 9251..9883 | + | 633 | Protein_14 | sugar ABC transporter permease | - |
| LH370_RS25010 (9873) | 9873..10760 | + | 888 | WP_001271561.1 | carbohydrate ABC transporter permease | - |
| LH370_RS25015 (10771) | 10771..11595 | + | 825 | WP_000922702.1 | phosphodiesterase | - |
| LH370_RS25020 (11601) | 11601..12674 | + | 1074 | WP_033549814.1 | sn-glycerol-3-phosphate import ATP-binding protein UgpC | VF |
| LH370_RS25025 (12667) | 12667..13977 | + | 1311 | WP_000476108.1 | ABC transporter substrate-binding protein | - |
| LH370_RS25030 (14036) | 14036..14344 | - | 309 | Protein_19 | IS4 family transposase ISEc13 | Transposase |
| LH370_RS25035 (14421) | 14421..14594 | - | 174 | WP_000338295.1 | Tn3 family transposase | - |
| LH370_RS25040 (14676) | 14676..15156 | - | 481 | Protein_21 | IS3 family transposase IS629 | Transposase |
| LH370_RS25045 (15240) | 15240..16748 | - | 1509 | WP_001189123.1 | group II intron reverse transcriptase/maturase | - |
| LH370_RS25050 (17421) | 17421..18142 | - | 722 | Protein_23 | IS3 family transposase IS629 | Transposase |
| LH370_RS25055 (18167) | 18167..18871 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| LH370_RS25060 (18924) | 18924..19775 | - | 852 | Protein_25 | IS4 family transposase IS10R | Transposase |
| LH370_RS25065 (19866) | 19866..19979 | + | 114 | Protein_26 | IS6 family transposase | - |
| LH370_RS25070 (20117) | 20117..20287 | + | 171 | Protein_27 | DsbA family protein | - |
| LH370_RS25075 (20277) | 20277..20783 | + | 507 | WP_000949452.1 | protein disulfide oxidoreductase | - |
| LH370_RS25080 (21020) | 21020..21781 | + | 762 | WP_001225378.1 | Na(+)-translocating NADH-quinone reductase subunit C | - |
| LH370_RS25085 (22128) | 22128..24014 | + | 1887 | WP_000118029.1 | FTR1 family protein | - |
| LH370_RS25090 (24055) | 24055..24582 | + | 528 | WP_000178050.1 | iron transporter | - |
| LH370_RS25095 (24686) | 24686..26065 | + | 1380 | WP_000119836.1 | Fe-S-containing protein | - |
| LH370_RS25100 (26068) | 26068..27351 | + | 1284 | WP_000964653.1 | ABC transporter permease | - |
| LH370_RS25105 (27341) | 27341..28471 | + | 1131 | WP_000729220.1 | ABC transporter permease | - |
| LH370_RS25110 (28476) | 28476..29171 | + | 696 | WP_000117262.1 | Lipoprotein-releasing system ATP-binding protein LolD | VF |
| LH370_RS25115 (29158) | 29158..29643 | + | 486 | WP_001267177.1 | TlpA disulfide reductase family protein | - |
| LH370_RS25120 (29668) | 29668..30153 | + | 486 | WP_000874189.1 | hypothetical protein | - |
| LH370_RS25125 (30275) | 30275..30805 | + | 531 | Protein_38 | histidine-type phosphatase | - |
| LH370_RS25130 (30863) | 30863..31567 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| LH370_RS25135 (31632) | 31632..32555 | - | 924 | Protein_40 | IS91 family transposase ISAzo26 | Transposase |
| LH370_RS25140 (32700) | 32700..33197 | + | 498 | WP_001083725.1 | Dihydrofolate reductase | ARG |
| LH370_RS25145 (33309) | 33309..33599 | + | 291 | WP_001336345.1 | DUF1010 domain-containing protein | - |
| LH370_RS25150 (33605) | 33605..34443 | + | 839 | Protein_43 | Streptomycin 3''-adenylyltransferase | ARG |
| LH370_RS25155 (34560) | 34560..34907 | + | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| LH370_RS25160 (34901) | 34901..35740 | + | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| LH370_RS25165 (36145) | 36145..37686 | + | 1542 | WP_000050481.1 | IS91 family transposase ISVsa3 | Transposase |
| LH370_RS25170 (37999) | 37999..38373 | + | 375 | Protein_47 | protein-disulfide reductase DsbD family protein | - |
| LH370_RS25175 (38473) | 38473..39030 | + | 558 | Protein_48 | twin-arginine translocation (TAT) pathway signal sequence domain protein | - |
| LH370_RS25180 (39041) | 39041..39679 | - | 639 | WP_004201168.1 | phosphoribosylanthranilate isomerase | - |
| LH370_RS25185 (39684) | 39684..40049 | - | 366 | WP_004201167.1 | bleomycin binding protein Ble-MBL | - |
| LH370_RS25190 (40053) | 40053..40865 | - | 813 | WP_023408309.1 | Metallo-beta-lactamase type 2 | ARG |
| LH370_RS25195 (40966) | 40966..41259 | - | 294 | Protein_52 | IS30 family transposase | - |
| LH370_RS25200 (41424) | 41424..42128 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| LH370_RS25205 (42322) | 42322..42672 | - | 351 | Protein_54 | 60 kDa chaperonin | VF |
| LH370_RS25210 (42735) | 42735..43283 | + | 549 | WP_014342204.1 | cation:proton antiporter | - |
| LH370_RS25215 (43364) | 43364..44119 | - | 756 | WP_012372818.1 | 16S rRNA (guanine(1405)-N(7))-methyltransferase | ARG |
| LH370_RS25220 (44289) | 44289..45149 | - | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| LH370_RS25225 (45332) | 45332..45661 | - | 330 | Protein_58 | recombinase family protein | - |
| LH370_RS25230 (45724) | 45724..46428 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| LH370_RS25235 (46494) | 46494..47039 | + | 546 | Protein_60 | Tn3 family transposase TnpA_Tn3 | Transposase |
| LH370_RS25240 (47075) | 47075..47490 | - | 416 | Protein_61 | IS1-like element IS1B family transposase | - |
| LH370_RS25245 (47739) | 47739..48140 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| LH370_RS25250 (48073) | 48073..48330 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| LH370_RS25255 (48423) | 48423..49076 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| LH370_RS25260 (49174) | 49174..49314 | - | 141 | WP_001333237.1 | hypothetical protein | - |
| LH370_RS25265 (50015) | 50015..50872 | - | 858 | WP_060591631.1 | incFII family plasmid replication initiator RepA | - |
| LH370_RS25270 (50865) | 50865..50939 | - | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| LH370_RS25275 (51177) | 51177..51431 | - | 255 | WP_000083830.1 | replication regulatory protein RepA | - |
| LH370_RS25280 (51671) | 51671..52261 | - | 591 | WP_000766807.1 | DUF2726 domain-containing protein | - |
| LH370_RS25285 (52299) | 52299..52508 | - | 210 | WP_001298565.1 | hemolysin expression modulator Hha | - |
| LH370_RS25290 (52554) | 52554..53015 | - | 462 | WP_001233838.1 | thermonuclease family protein | - |
| LH370_RS25295 (53260) | 53260..53472 | - | 213 | WP_001309245.1 | ANR family transcriptional regulator | - |
| LH370_RS25300 (53601) | 53601..54161 | - | 561 | WP_000139323.1 | fertility inhibition protein FinO | - |
| LH370_RS25305 (54264) | 54264..55124 | - | 861 | WP_000704523.1 | putative protein YcjY | VF |
| LH370_RS25310 (55183) | 55183..55929 | - | 747 | WP_000205725.1 | conjugal transfer pilus acetylase TraX | - |
| LH370_RS25315 (55949) | 55949..61219 | - | 5271 | WP_000948354.1 | Multifunctional conjugation protein TraI | Relaxase |
| LH370_RS25320 (61219) | 61219..63489 | - | 2271 | WP_000009328.1 | type IV conjugative transfer system coupling protein TraD | - |
| LH370_RS25325 (63540) | 63540..64277 | - | 738 | WP_000199905.1 | hypothetical protein | - |
| LH370_RS25330 (64480) | 64480..65211 | - | 732 | WP_000782451.1 | conjugal transfer complement resistance protein TraT | - |
| LH370_RS25335 (65260) | 65260..65745 | - | 486 | WP_000605870.1 | hypothetical protein | - |
| LH370_RS25340 (65761) | 65761..68583 | - | 2823 | WP_001007039.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| LH370_RS25345 (68580) | 68580..69953 | - | 1374 | WP_000944331.1 | conjugal transfer pilus assembly protein TraH | - |
| LH370_RS25350 (69940) | 69940..70332 | - | 393 | WP_000660699.1 | F-type conjugal transfer protein TrbF | - |
| LH370_RS25355 (70313) | 70313..70660 | - | 348 | WP_001309242.1 | P-type conjugative transfer protein TrbJ | - |
| LH370_RS25360 (70590) | 70590..71135 | - | 546 | WP_000059831.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| LH370_RS25365 (71122) | 71122..71406 | - | 285 | WP_000624194.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| LH370_RS25370 (71525) | 71525..71869 | - | 345 | WP_000556796.1 | conjugal transfer protein TrbA | - |
| LH370_RS25375 (71883) | 71883..72626 | - | 744 | WP_001030371.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| LH370_RS25380 (72619) | 72619..72876 | - | 258 | WP_000864353.1 | conjugal transfer protein TrbE | - |
| LH370_RS25385 (72903) | 72903..74753 | - | 1851 | WP_000821856.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| LH370_RS25390 (74750) | 74750..75388 | - | 639 | WP_046960657.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| LH370_RS25395 (75397) | 75397..76389 | - | 993 | WP_001553833.1 | conjugal transfer pilus assembly protein TraU | - |
| LH370_RS25400 (76386) | 76386..77018 | - | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| LH370_RS25405 (77015) | 77015..77401 | - | 387 | WP_000099690.1 | type-F conjugative transfer system protein TrbI | - |
| LH370_RS25410 (77398) | 77398..80025 | - | 2628 | WP_001064264.1 | type IV secretion system protein TraC | - |
| LH370_RS25415 (80185) | 80185..80406 | - | 222 | WP_001278692.1 | conjugal transfer protein TraR | - |
| LH370_RS25420 (80541) | 80541..81056 | - | 516 | WP_000809832.1 | type IV conjugative transfer system lipoprotein TraV | - |
| LH370_RS25425 (81053) | 81053..81304 | - | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
| LH370_RS25430 (81297) | 81297..81617 | - | 321 | Protein_99 | conjugal transfer protein TrbD | - |
| LH370_RS25435 (81604) | 81604..82194 | - | 591 | WP_000002787.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| LH370_RS25440 (82184) | 82184..83611 | - | 1428 | WP_001553836.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| LH370_RS25445 (83611) | 83611..84339 | - | 729 | WP_001230813.1 | type-F conjugative transfer system secretin TraK | - |
| LH370_RS25450 (84326) | 84326..84892 | - | 567 | WP_000399790.1 | type IV conjugative transfer system protein TraE | - |
| LH370_RS25455 (84914) | 84914..85225 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| LH370_RS25460 (85240) | 85240..85605 | - | 366 | WP_000340282.1 | type IV conjugative transfer system pilin TraA | - |
| LH370_RS25465 (85648) | 85648..85863 | - | 216 | WP_001352842.1 | conjugal transfer relaxosome protein TraY | - |
| LH370_RS25470 (85999) | 85999..86646 | - | 648 | WP_000332520.1 | conjugal transfer transcriptional regulator TraJ | - |
| LH370_RS25475 (86837) | 86837..87220 | - | 384 | WP_001063020.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| LH370_RS25480 (87590) | 87590..88162 | + | 573 | WP_000949660.1 | hypothetical protein | VF |
| LH370_RS25485 (88458) | 88458..89279 | - | 822 | WP_001234465.1 | DUF932 domain-containing protein | - |
| LH370_RS25490 (89398) | 89398..89685 | - | 288 | WP_000107242.1 | hypothetical protein | - |
| LH370_RS25495 (89710) | 89710..89916 | - | 207 | WP_000275854.1 | hypothetical protein | - |
| LH370_RS25500 (89986) | 89986..90283 | + | 298 | Protein_113 | hypothetical protein | - |
| LH370_RS25505 (90584) | 90584..90709 | - | 126 | WP_096937776.1 | type I toxin-antitoxin system Hok family toxin | - |
| LH370_RS25510 (90651) | 90651..90800 | - | 150 | Protein_115 | DUF5431 family protein | - |
| - (92262) | 92262..92452 | - | 191 | NuclAT_0 | - | - |
| - (92262) | 92262..92452 | - | 191 | NuclAT_0 | - | - |
| - (92262) | 92262..92452 | - | 191 | NuclAT_0 | - | - |
| - (92262) | 92262..92452 | - | 191 | NuclAT_0 | - | - |
| LH370_RS25520 (92421) | 92421..92526 | - | 106 | Protein_117 | plasmid SOS inhibition protein A | - |
| LH370_RS25525 (92681) | 92681..92998 | + | 318 | Protein_118 | IS110 family transposase | - |
| LH370_RS25530 (93287) | 93287..93538 | - | 252 | Protein_119 | iron-containing alcohol dehydrogenase | - |
| LH370_RS25535 (93623) | 93623..94135 | - | 513 | WP_223350513.1 | potassium channel family protein | - |
| LH370_RS25540 (94262) | 94262..94955 | - | 694 | Protein_121 | IS1 family transposase IS1A | Transposase |
| LH370_RS25545 (95012) | 95012..95116 | + | 105 | Protein_122 | thiosulfate reductase cytochrome B subunit | - |
| LH370_RS25550 (95362) | 95362..96756 | - | 1395 | WP_001037799.1 | carbohydrate porin | - |
| LH370_RS25555 (96951) | 96951..98384 | - | 1434 | WP_024170639.1 | glycoside hydrolase family 32 protein | - |
| LH370_RS25560 (98381) | 98381..99658 | - | 1278 | WP_001083369.1 | MFS transporter | - |
| LH370_RS25565 (99721) | 99721..101847 | - | 2127 | WP_000253905.1 | alpha-galactosidase | - |
| LH370_RS25570 (101943) | 101943..102953 | - | 1011 | WP_000053332.1 | substrate-binding domain-containing protein | - |
| LH370_RS25575 (103111) | 103111..103869 | - | 759 | Protein_128 | site-specific integrase | - |
| LH370_RS25580 (103960) | 103960..105188 | + | 1229 | WP_152924612.1 | IS3 family transposase IS2 | Transposase |
| LH370_RS25585 (105173) | 105173..105742 | + | 570 | WP_089634947.1 | hypothetical protein | - |
| LH370_RS25590 (106673) | 106673..106936 | - | 264 | WP_071781663.1 | hypothetical protein | - |
| LH370_RS25595 (106843) | 106843..107061 | - | 219 | WP_001496291.1 | hypothetical protein | - |
| LH370_RS25600 (107087) | 107087..107650 | - | 564 | WP_001348621.1 | class I SAM-dependent methyltransferase | - |
| LH370_RS25605 (107698) | 107698..109059 | - | 1362 | WP_000170714.1 | DUF3560 domain-containing protein | - |
| LH370_RS25610 (109111) | 109111..109341 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| LH370_RS25615 (110376) | 110376..110567 | - | 192 | WP_001027516.1 | hypothetical protein | - |
| LH370_RS25620 (110564) | 110564..110986 | - | 423 | WP_000271753.1 | DUF1380 family protein | - |
| LH370_RS25625 (111033) | 111033..111458 | - | 426 | WP_001198928.1 | antirestriction protein | - |
| LH370_RS25630 (111875) | 111875..112651 | - | 777 | WP_001753849.1 | hypothetical protein | - |
| LH370_RS25635 (112702) | 112702..113220 | - | 519 | WP_123325260.1 | DUF1380 family protein | - |
| LH370_RS25640 (113150) | 113150..113371 | - | 222 | WP_001104873.1 | hypothetical protein | - |
| LH370_RS25645 (113372) | 113372..114055 | - | 684 | WP_000086185.1 | DNA methylase | - |
| LH370_RS25650 (114132) | 114132..114443 | - | 312 | WP_011254640.1 | hypothetical protein | - |
| LH370_RS25655 (114440) | 114440..115342 | - | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| LH370_RS25660 (116209) | 116209..117180 | - | 972 | WP_000817036.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| LH370_RS25665 (117180) | 117180..118346 | - | 1167 | WP_000772446.1 | Sporulation initiation inhibitor protein Soj | VF |
| LH370_RS25670 (118934) | 118934..119689 | - | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| LH370_RS25675 (120463) | 120463..121269 | - | 807 | WP_000016982.1 | site-specific integrase | - |
| LH370_RS25680 (121270) | 121270..121575 | - | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| LH370_RS25685 (121577) | 121577..121795 | - | 219 | WP_000813634.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| LH370_RS25690 (122429) | 122429..122626 | + | 198 | WP_000215657.1 | hypothetical protein | - |
| LH370_RS25695 (122623) | 122623..122907 | - | 285 | WP_000642771.1 | hypothetical protein | - |
| LH370_RS25700 (122927) | 122927..124060 | - | 1134 | WP_000545983.1 | DUF3800 domain-containing protein | - |
| LH370_RS25705 (124323) | 124323..127442 | - | 3120 | WP_001553851.1 | hypothetical protein | - |
| LH370_RS25710 (127749) | 127749..127979 | + | 231 | WP_001261287.1 | type II toxin-antitoxin system VapB family antitoxin | - |
| LH370_RS25715 (127976) | 127976..128392 | + | 417 | WP_001044768.1 | type II toxin-antitoxin system VapC family toxin | - |
| LH370_RS25720 (128554) | 128554..130692 | - | 2139 | WP_000350635.1 | AAA family ATPase | - |
| LH370_RS25730 (132233) | 132233..133203 | - | 971 | Protein_159 | hypothetical protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|