MGE detailed information
MGE type: Integrative_Conjugative_Elements MGE length: 134224 bp
Accession: NZ_CP076471 Location: 92765..226988 Organism: Enterococcus faecium strain UAMS_EF58 Replicon: chromosome
Accession: NZ_CP076471 Location: 92765..226988 Organism: Enterococcus faecium strain UAMS_EF58 Replicon: chromosome
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KPU57_RS00480 (KPU57_00475) | 87867..88055 | - | 189 | WP_002290463.1 | 50S ribosomal protein L28 | - |
| KPU57_RS00485 (KPU57_00480) | 88325..88687 | + | 363 | WP_002294298.1 | Asp23/Gls24 family envelope stress response protein | - |
| KPU57_RS00490 (KPU57_00485) | 88739..90421 | + | 1683 | WP_002301169.1 | DAK2 domain-containing protein | - |
| KPU57_RS00495 (KPU57_00490) | 90538..92574 | + | 2037 | WP_002301167.1 | ATP-dependent DNA helicase RecG | - |
| KPU57_RS00500 (KPU57_00495) | 92623..93624 | + | 1002 | WP_002289721.1 | phosphate acyltransferase PlsX | - |
| KPU57_RS00505 (KPU57_00500) | 93746..93988 | + | 243 | WP_002294295.1 | hypothetical protein | VF |
| KPU57_RS00510 (KPU57_00505) | 94256..95260 | + | 1005 | WP_002287889.1 | Oligopeptide transport ATP-binding protein OppD | VF |
| KPU57_RS00515 (KPU57_00510) | 95261..96205 | + | 945 | WP_002287891.1 | hypothetical protein | VF |
| KPU57_RS00520 (KPU57_00515) | 96205..97167 | + | 963 | WP_002287892.1 | ABC transporter permease | - |
| KPU57_RS00525 (KPU57_00520) | 97194..98108 | + | 915 | WP_002287893.1 | ABC transporter permease | - |
| KPU57_RS00530 (KPU57_00525) | 98134..99915 | + | 1782 | WP_002287894.1 | oligopeptide ABC transporter substrate-binding protein | - |
| KPU57_RS00535 (KPU57_00530) | 100263..100949 | + | 687 | WP_002287896.1 | ribonuclease III | - |
| KPU57_RS00540 (KPU57_00535) | 100969..104550 | + | 3582 | WP_002301166.1 | chromosome segregation protein SMC | - |
| KPU57_RS00545 (KPU57_00540) | 104559..105368 | + | 810 | WP_002348798.1 | Cof-type HAD-IIB family hydrolase | - |
| KPU57_RS00550 (KPU57_00545) | 105380..106378 | + | 999 | WP_002301165.1 | signal recognition particle-docking protein FtsY | - |
| KPU57_RS00555 (KPU57_00550) | 106565..108832 | + | 2268 | WP_002294288.1 | bifunctional glutamate--cysteine ligase GshA/glutathione synthetase GshB | - |
| KPU57_RS00560 (KPU57_00555) | 109016..109969 | + | 954 | WP_002287760.1 | IS30 family transposase IS1252 | Transposase |
| KPU57_RS00565 (KPU57_00560) | 109987..110439 | - | 453 | WP_002294287.1 | YueI family protein | - |
| KPU57_RS00570 (KPU57_00565) | 110589..111539 | + | 951 | WP_002294286.1 | Cell division protein FtsX | VF |
| KPU57_RS00575 (KPU57_00570) | 111532..112491 | + | 960 | WP_002301163.1 | putative CtpA-like serine protease | VF |
| KPU57_RS00580 (KPU57_00575) | 112488..113243 | + | 756 | WP_002301162.1 | UvrABC system protein B | VF |
| KPU57_RS00585 (KPU57_00580) | 113266..114219 | + | 954 | WP_002301160.1 | 30S ribosomal protein S6 | VF |
| KPU57_RS00590 (KPU57_00585) | 114863..115159 | - | 297 | WP_002287909.1 | phenylalanyl-tRNA synthetase subunit alpha | - |
| KPU57_RS00595 (KPU57_00590) | 115515..115871 | + | 357 | WP_002287910.1 | iron-sulfur cluster biosynthesis family protein | - |
| KPU57_RS00600 (KPU57_00595) | 115881..116780 | + | 900 | WP_002348747.1 | metallophosphoesterase | - |
| KPU57_RS00605 (KPU57_00600) | 117013..117972 | - | 960 | WP_002301399.1 | IS30 family transposase IS1062 | Transposase |
| KPU57_RS00610 (KPU57_00605) | 118230..119675 | + | 1446 | WP_002322872.1 | IS1182 family transposase ISEfa7 | Transposase |
| KPU57_RS00615 (KPU57_00610) | 119834..121126 | + | 1293 | WP_000122610.1 | ISL3 family transposase IS1251 | Transposase |
| KPU57_RS00620 (KPU57_00615) | 121228..121962 | - | 735 | WP_002348590.1 | MIP/aquaporin family protein | - |
| KPU57_RS00625 (KPU57_00620) | 122288..122698 | + | 411 | WP_002301190.1 | CidA/LrgA family protein | - |
| KPU57_RS00630 (KPU57_00625) | 122691..123392 | + | 702 | WP_002294273.1 | LrgB family protein | - |
| KPU57_RS00635 (KPU57_00630) | 123392..125005 | + | 1614 | WP_002348592.1 | helix-turn-helix domain-containing protein | - |
| KPU57_RS00640 (KPU57_00635) | 124995..125216 | + | 222 | WP_002290506.1 | DUF2829 domain-containing protein | - |
| KPU57_RS00645 (KPU57_00640) | 125213..125974 | + | 762 | WP_002297929.1 | Guanine/hypoxanthine permease PbuG | VF |
| KPU57_RS00650 (KPU57_00645) | 126355..126864 | + | 510 | WP_002294268.1 | QueT transporter family protein | - |
| KPU57_RS00655 (KPU57_00650) | 126934..127473 | - | 540 | WP_002294267.1 | biotin transporter BioY | - |
| KPU57_RS00660 (KPU57_00655) | 127613..128224 | - | 612 | WP_002294265.1 | 30S ribosomal protein S4 | - |
| KPU57_RS00665 (KPU57_00660) | 128486..129337 | + | 852 | WP_002348593.1 | formate/nitrite transporter family protein | - |
| KPU57_RS00670 (KPU57_00665) | 129365..130000 | + | 636 | WP_002294262.1 | DNA alkylation repair protein | - |
| KPU57_RS00675 (KPU57_00670) | 130020..130793 | + | 774 | WP_002294261.1 | Cof-type HAD-IIB family hydrolase | - |
| KPU57_RS00680 (KPU57_00675) | 131201..131998 | + | 798 | WP_002348595.1 | TIGR00282 family metallophosphoesterase | - |
| KPU57_RS00685 (KPU57_00680) | 131976..132389 | + | 414 | WP_002297923.1 | YlbF family regulator | - |
| KPU57_RS00690 (KPU57_00685) | 132373..135018 | + | 2646 | WP_002294258.1 | DNA mismatch repair protein MutS | - |
| KPU57_RS00695 (KPU57_00690) | 135036..137144 | + | 2109 | WP_002301736.1 | DNA mismatch repair endonuclease MutL | - |
| KPU57_RS00700 (KPU57_00695) | 137166..137726 | + | 561 | WP_002348596.1 | Maf family protein | - |
| KPU57_RS00705 (KPU57_00700) | 137865..139160 | - | 1296 | WP_002297218.1 | ISL3 family transposase ISEfa11 | Transposase |
| KPU57_RS00710 (KPU57_00705) | 139420..139614 | + | 195 | WP_002285758.1 | hypothetical protein | - |
| KPU57_RS00715 (KPU57_00710) | 139604..139957 | + | 354 | WP_002287659.1 | IS66 family transposase ISDeal1 | Transposase |
| KPU57_RS00720 (KPU57_00715) | 140059..141606 | + | 1548 | WP_002296127.1 | IS66 family transposase ISRob1 | Transposase |
| KPU57_RS00725 (KPU57_00720) | 141686..143674 | - | 1989 | WP_002348864.1 | PTS system trehalose-specific EIIBC component | - |
| KPU57_RS00730 (KPU57_00725) | 143897..144610 | + | 714 | WP_002294254.1 | trehalose operon repressor | - |
| KPU57_RS00735 (KPU57_00730) | 144687..145133 | + | 447 | WP_002294252.1 | Coenzyme A disulfide reductase | VF |
| KPU57_RS00740 (KPU57_00735) | 145303..145905 | + | 603 | WP_002290528.1 | Holliday junction branch migration protein RuvA | - |
| KPU57_RS00745 (KPU57_00740) | 145918..146919 | + | 1002 | WP_002289812.1 | Holliday junction ATP-dependent DNA helicase RuvB | VF |
| KPU57_RS00750 (KPU57_00745) | 146948..147526 | + | 579 | WP_002341570.1 | TetR/AcrR family transcriptional regulator | - |
| KPU57_RS00755 (KPU57_00750) | 147578..148060 | + | 483 | WP_002294249.1 | 50S ribosomal protein L9 | VF |
| KPU57_RS00760 (KPU57_00755) | 148177..148551 | + | 375 | WP_002289815.1 | hypothetical protein | - |
| KPU57_RS00765 (KPU57_00760) | 148968..150146 | + | 1179 | WP_002324322.1 | IS256 family transposase ISEfm2 | Transposase |
| KPU57_RS00770 (KPU57_00765) | 150684..152036 | - | 1353 | WP_002294246.1 | branched-chain amino acid transport system II carrier protein | - |
| KPU57_RS00775 (KPU57_00770) | 152183..152773 | + | 591 | WP_002297079.1 | TMEM175 family protein | - |
| KPU57_RS00780 (KPU57_00775) | 152901..154250 | - | 1350 | WP_002294242.1 | amino acid permease | - |
| KPU57_RS00785 (KPU57_00780) | 154498..155790 | + | 1293 | WP_000122610.1 | ISL3 family transposase IS1251 | Transposase |
| KPU57_RS00790 (KPU57_00785) | 155925..156665 | - | 741 | WP_002294240.1 | Phosphocarrier protein HPr | VF |
| KPU57_RS00795 (KPU57_00790) | 156678..158270 | - | 1593 | WP_002297081.1 | ABC transporter permease subunit | - |
| KPU57_RS00800 (KPU57_00795) | 158838..159134 | - | 297 | WP_002293448.1 | hypothetical protein | - |
| KPU57_RS00805 (KPU57_00800) | 159310..160035 | + | 726 | WP_002294236.1 | NAD-dependent protein deacylase | - |
| KPU57_RS00810 (KPU57_00805) | 160028..160870 | + | 843 | WP_002301156.1 | Triosephosphate isomerase | VF |
| KPU57_RS00815 (KPU57_00810) | 160873..161394 | + | 522 | WP_002294232.1 | transcription repressor NadR | - |
| KPU57_RS00820 (KPU57_00815) | 161647..162210 | - | 564 | WP_002289284.1 | peptide deformylase | - |
| KPU57_RS00825 (KPU57_00820) | 162461..162730 | + | 270 | WP_002289282.1 | 30S ribosomal protein S15 | - |
| KPU57_RS00830 (KPU57_00825) | 162918..165044 | + | 2127 | WP_002297086.1 | polyribonucleotide nucleotidyltransferase | - |
| KPU57_RS00835 (KPU57_00830) | 165554..165820 | + | 267 | WP_002289280.1 | GlsB/YeaQ/YmgE family stress response membrane protein | - |
| KPU57_RS00840 (KPU57_00835) | 165997..167955 | + | 1959 | WP_002321207.1 | KUP/HAK/KT family potassium transporter | - |
| KPU57_RS00845 (KPU57_00840) | 168309..169610 | + | 1302 | WP_002294228.1 | hemolysin family protein | - |
| KPU57_RS00850 (KPU57_00845) | 169986..171281 | - | 1296 | WP_002297185.1 | ISL3 family transposase ISEfa5 | Transposase |
| KPU57_RS00855 (KPU57_00850) | 171418..172527 | - | 1110 | Protein_170 | IS110 family transposase ISSsu7 | Transposase |
| KPU57_RS00860 (KPU57_00855) | 172874..174244 | - | 1371 | WP_002289277.1 | MATE family efflux transporter | - |
| KPU57_RS00865 (KPU57_00860) | 174426..174749 | - | 324 | WP_002289744.1 | DUF960 domain-containing protein | - |
| KPU57_RS00870 (KPU57_00865) | 175074..175682 | - | 609 | WP_002299254.1 | 50S ribosomal protein L25/general stress protein Ctc | - |
| KPU57_RS00875 (KPU57_00870) | 176012..176728 | + | 717 | WP_002348768.1 | 16S rRNA pseudouridine(516) synthase | - |
| KPU57_RS00880 (KPU57_00875) | 176741..177436 | + | 696 | WP_002289749.1 | YjjG family noncanonical pyrimidine nucleotidase | - |
| KPU57_RS00885 (KPU57_00880) | 177520..178149 | + | 630 | WP_002289751.1 | uridine kinase | - |
| KPU57_RS00890 (KPU57_00885) | 178664..180003 | + | 1340 | WP_086953915.1 | IS3 family transposase ISEnfa3 | Transposase |
| KPU57_RS00895 (KPU57_00890) | 180072..180674 | + | 603 | WP_002294220.1 | VTT domain-containing protein | - |
| KPU57_RS00900 (KPU57_00895) | 180696..181184 | + | 489 | WP_002296548.1 | GNAT family N-acetyltransferase | - |
| KPU57_RS00905 (KPU57_00900) | 181505..182878 | + | 1374 | WP_002294217.1 | hypothetical protein | - |
| KPU57_RS00910 (KPU57_00905) | 182862..183329 | + | 468 | WP_002294214.1 | YaiI/YqxD family protein | - |
| KPU57_RS00915 (KPU57_00910) | 183578..185323 | - | 1746 | WP_002329999.1 | AarF/UbiB family protein | - |
| KPU57_RS00920 (KPU57_00915) | 185519..186595 | + | 1077 | WP_002293424.1 | D-alanine--D-alanine ligase | - |
| KPU57_RS00925 (KPU57_00920) | 186748..188100 | + | 1353 | WP_002317074.1 | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase | - |
| KPU57_RS00930 (KPU57_00925) | 188422..189933 | + | 1512 | WP_002294211.1 | DEAD/DEAH box helicase | - |
| KPU57_RS00935 (KPU57_00930) | 190063..190413 | + | 351 | WP_002294209.1 | holo-ACP synthase | - |
| KPU57_RS00940 (KPU57_00935) | 190429..191550 | + | 1122 | WP_002294207.1 | alanine racemase | - |
| KPU57_RS00945 (KPU57_00940) | 191561..191923 | + | 363 | WP_002289874.1 | type II toxin-antitoxin system PemK/MazF family toxin | - |
| KPU57_RS00950 (KPU57_00945) | 192099..192368 | - | 270 | WP_002293413.1 | 30S ribosomal protein S14 | - |
| KPU57_RS00955 (KPU57_00950) | 192558..193505 | + | 948 | WP_002294206.1 | NADP-dependent oxidoreductase | - |
| KPU57_RS00960 (KPU57_00955) | 193651..194946 | - | 1296 | WP_002297185.1 | ISL3 family transposase ISEfa5 | Transposase |
| KPU57_RS00965 (KPU57_00960) | 195213..196172 | + | 960 | WP_002301399.1 | IS30 family transposase IS1062 | Transposase |
| KPU57_RS00970 (KPU57_00965) | 196398..199103 | + | 2706 | WP_002294203.1 | YhgE/Pip domain-containing protein | - |
| KPU57_RS00975 (KPU57_00970) | 199700..201523 | + | 1824 | WP_002294202.1 | APC family permease | - |
| KPU57_RS00980 (KPU57_00975) | 201665..201850 | - | 186 | WP_002348885.1 | hypothetical protein | - |
| KPU57_RS00985 (KPU57_00980) | 202325..202588 | + | 264 | WP_002294199.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| KPU57_RS00990 (KPU57_00985) | 202588..202854 | + | 267 | WP_002301121.1 | Txe/YoeB family addiction module toxin | Toxin Detail |
| KPU57_RS00995 | 203055..203543 | + | 489 | WP_002301120.1 | mannosyl-glycoprotein endo-beta-N-acetylglucosamidase | - |
| KPU57_RS15885 | 203503..203625 | + | 123 | WP_285894660.1 | hypothetical protein | - |
| KPU57_RS01000 (KPU57_00995) | 204085..204756 | - | 672 | WP_002301116.1 | ABC transporter permease | - |
| KPU57_RS01005 (KPU57_01000) | 204753..205670 | - | 918 | WP_002301114.1 | osmoprotectant ABC transporter substrate-binding protein | - |
| KPU57_RS01010 (KPU57_01005) | 205667..206308 | - | 642 | WP_002293405.1 | ABC transporter permease | - |
| KPU57_RS01015 (KPU57_01010) | 206312..207487 | - | 1176 | WP_002348889.1 | Carnitine transport ATP-binding protein OpuCA | VF |
| KPU57_RS01020 (KPU57_01015) | 207680..208711 | + | 1032 | WP_002350806.1 | tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA | - |
| KPU57_RS01025 (KPU57_01020) | 208905..210197 | + | 1293 | WP_000122610.1 | ISL3 family transposase IS1251 | Transposase |
| KPU57_RS01030 (KPU57_01025) | 210387..211340 | + | 954 | WP_002287760.1 | IS30 family transposase IS1252 | Transposase |
| KPU57_RS01035 (KPU57_01030) | 211431..212726 | + | 1296 | WP_002296623.1 | ISL3 family transposase IS1251 | Transposase |
| KPU57_RS01040 (KPU57_01035) | 212888..214183 | + | 1296 | WP_002297185.1 | ISL3 family transposase ISEfa5 | Transposase |
| KPU57_RS01045 (KPU57_01040) | 214893..217532 | + | 2640 | WP_002289743.1 | cation-translocating P-type ATPase | - |
| KPU57_RS01050 (KPU57_01045) | 217700..218398 | - | 699 | WP_002294185.1 | DUF975 family protein | - |
| KPU57_RS01055 (KPU57_01050) | 218501..219454 | - | 954 | WP_002287760.1 | IS30 family transposase IS1252 | Transposase |
| KPU57_RS01060 (KPU57_01055) | 219683..220828 | + | 1146 | WP_002294183.1 | tRNA guanosine(34) transglycosylase Tgt | - |
| KPU57_RS01065 (KPU57_01060) | 220925..221305 | + | 381 | WP_002300794.1 | preprotein translocase subunit YajC | - |
| KPU57_RS01070 (KPU57_01065) | 221610..224207 | + | 2598 | WP_010782512.1 | Ascorbate-specific PTS system EIIB component | VF |
| KPU57_RS01075 (KPU57_01070) | 224115..225743 | - | 1629 | WP_226816272.1 | IS1182 family transposase ISEfa7 | Transposase |
| KPU57_RS01080 (KPU57_01075) | 226002..226956 | + | 955 | Protein_216 | glycoside hydrolase family 88 protein | - |
| KPU57_RS01085 (KPU57_01080) | 226973..227997 | + | 1025 | Protein_217 | TRAP transporter substrate-binding protein | - |
| KPU57_RS01090 (KPU57_01085) | 228003..228481 | + | 479 | Protein_218 | TRAP transporter small permease | - |
| KPU57_RS01095 (KPU57_01090) | 228497..229051 | + | 555 | Protein_219 | TRAP transporter large permease subunit | - |
| KPU57_RS01100 (KPU57_01095) | 229107..230446 | + | 1340 | WP_086953915.1 | IS3-like element ISEnfa3 family transposase | - |
| KPU57_RS01105 (KPU57_01100) | 230490..230627 | + | 138 | Protein_221 | TRAP transporter large permease subunit | - |
| KPU57_RS01110 (KPU57_01105) | 230660..230983 | + | 324 | Protein_222 | 5-dehydro-4-deoxy-D-glucuronate isomerase | - |
| KPU57_RS01115 (KPU57_01110) | 231003..231806 | + | 804 | WP_033582433.1 | gluconate 5-dehydrogenase | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|