MGE detailed information

MGE type: Non-Mobilizable plasmid        MGE length: 192427 bp
Accession: NZ_CP066444        Location: 1..192427         Organism: Enterococcus faecium strain Dallas 71_2       Replicon: plasmid p71_2_192kb


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JCP66_RS14125 () 1..1041 + 1041 WP_002326172.1 replication initiator protein A -
JCP66_RS14130 () 1865..2197 + 333 WP_002323647.1 hypothetical protein -
JCP66_RS14135 () 2816..3157 + 342 WP_002295674.1 DUF5406 domain-containing protein -
JCP66_RS14140 () 3394..4644 - 1251 WP_002287107.1 IS110 family transposase ISSpn10 Transposase
JCP66_RS14145 () 5054..5293 + 240 WP_002295673.1 hypothetical protein -
JCP66_RS14150 () 5360..5569 + 210 WP_002295672.1 hypothetical protein -
JCP66_RS14155 () 5629..6300 + 672 WP_002336710.1 class A sortase -
JCP66_RS14160 () 6353..8329 + 1977 WP_010729784.1 isopeptide-forming domain-containing fimbrial protein -
JCP66_RS14165 () 8342..9097 + 756 WP_010729785.1 hypothetical protein VF
JCP66_RS14170 () 9094..9918 + 825 WP_002350398.1 hypothetical protein -
JCP66_RS14175 () 10219..12318 + 2100 WP_010729786.1 isopeptide-forming domain-containing fimbrial protein -
JCP66_RS14180 () 12356..14413 - 2058 WP_002350400.1 Beta-L-arabinobiosidase VF
JCP66_RS14185 () 14527..14739 - 213 WP_002296354.1 hypothetical protein -
JCP66_RS14190 () 14926..15393 + 468 WP_002296355.1 hypothetical protein -
JCP66_RS14195 () 15390..15632 + 243 WP_002321279.1 DUF5415 family protein -
JCP66_RS14200 () 15650..15952 + 303 WP_002296358.1 hypothetical protein -
JCP66_RS14205 () 16024..18078 + 2055 WP_002321280.1 hypothetical protein -
JCP66_RS14210 () 18078..20690 + 2613 WP_010729788.1 type IV secretory system conjugative DNA transfer family protein -
JCP66_RS14215 () 20687..23218 + 2532 WP_002321282.1 hypothetical protein -
JCP66_RS14220 () 23270..23602 + 333 WP_002326876.1 hypothetical protein -
JCP66_RS14225 () 23603..24196 + 594 WP_002313112.1 hypothetical protein -
JCP66_RS14230 () 24359..26053 + 1695 WP_198879751.1 ATPase -
JCP66_RS14235 () 26741..28618 + 1878 WP_002305177.1 group II intron reverse transcriptase/maturase -
JCP66_RS14240 () 28749..29126 + 378 Protein_23 ATPase -
JCP66_RS14245 () 29185..29448 + 264 WP_002297500.1 hypothetical protein -
JCP66_RS14250 () 29448..29783 + 336 WP_002297498.1 type II toxin-antitoxin system PemK/MazF family toxin -
JCP66_RS14255 () 29857..31059 + 1203 WP_002305180.1 glucosaminidase domain-containing protein -
JCP66_RS14260 () 31075..31719 + 645 WP_049055243.1 hypothetical protein -
JCP66_RS14265 () 31730..32536 + 807 WP_002304984.1 hypothetical protein -
JCP66_RS14270 () 32558..32788 + 231 WP_002304985.1 hypothetical protein -
JCP66_RS14275 () 33257..33553 + 297 WP_002305005.1 hypothetical protein -
JCP66_RS14280 () 33555..33977 + 423 WP_002305006.1 hypothetical protein -
JCP66_RS14285 () 33996..35588 + 1593 WP_042957057.1 hypothetical protein Relaxase
JCP66_RS14290 () 35609..35944 + 336 WP_002296380.1 hypothetical protein -
JCP66_RS14295 () 36090..36284 + 195 WP_002322479.1 hypothetical protein -
JCP66_RS14300 () 36420..37670 - 1251 WP_002287107.1 IS110 family transposase ISSpn10 Transposase
JCP66_RS14305 () 38080..40452 + 2373 WP_002317424.1 hypothetical protein -
JCP66_RS14310 () 40513..41982 + 1470 WP_002313123.1 toprim domain-containing protein -
JCP66_RS14315 () 41993..44002 + 2010 WP_002303486.1 DNA topoisomerase III -
JCP66_RS14320 () 44118..44267 + 150 WP_002295632.1 hypothetical protein -
JCP66_RS14325 () 44348..44944 + 597 WP_002299811.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein -
JCP66_RS14330 () 44957..45856 + 900 WP_002352365.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
JCP66_RS14335 () 45859..45990 + 132 WP_002301801.1 single-stranded DNA-binding protein -
JCP66_RS14340 () 46012..46344 + 333 WP_002305808.1 single-stranded DNA-binding protein -
JCP66_RS14345 () 46389..46622 + 234 WP_002303482.1 hypothetical protein -
JCP66_RS14350 () 46781..46903 - 123 WP_002295624.1 putative holin-like toxin -
JCP66_RS14355 () 47093..47317 + 225 WP_002305809.1 hypothetical protein -
JCP66_RS14360 () 47760..47966 + 207 WP_002305810.1 hypothetical protein -
JCP66_RS14365 () 47966..48217 + 252 WP_002300797.1 hypothetical protein -
JCP66_RS14370 () 48233..48388 + 156 WP_002300799.1 hypothetical protein -
JCP66_RS14375 () 48398..48670 + 273 WP_002300801.1 hypothetical protein -
JCP66_RS14380 () 49115..49294 + 180 WP_002300804.1 hypothetical protein -
JCP66_RS14385 () 49353..49709 + 357 WP_002311569.1 hypothetical protein -
JCP66_RS14390 () 50678..51631 - 954 WP_000222572.1 IS30 family transposase IS1252 Transposase
JCP66_RS14395 () 51752..52015 + 264 WP_002300807.1 uberolysin/carnocyclin family circular bacteriocin -
JCP66_RS14400 () 52387..53565 + 1179 WP_000997695.1 IS256 family transposase ISEf1 Transposase
JCP66_RS14405 () 53953..55899 + 1947 WP_002300833.1 PTS sugar transporter subunit IIA -
JCP66_RS14410 () 55902..56357 + 456 WP_002300835.1 PTS sugar transporter subunit IIA -
JCP66_RS14415 () 56371..57699 + 1329 WP_002300836.1 PTS galactitol transporter subunit IIC -
JCP66_RS14420 () 57733..58017 + 285 WP_002300838.1 PTS sugar transporter subunit IIB -
JCP66_RS14425 () 58019..58534 + 516 WP_002300840.1 YjbQ family protein -
JCP66_RS14430 () 58550..59212 + 663 WP_002300841.1 Ribulose-phosphate 3-epimerase VF
JCP66_RS14435 () 59219..59791 + 573 WP_002300842.1 3-hexulose-6-phosphate isomerase VF
JCP66_RS14440 () 59978..61498 - 1521 WP_002300843.1 IS66 family transposase ISDeal1 Transposase
JCP66_RS14445 () 61741..61926 - 186 WP_002305884.1 IS66 family transposase ISEbi1 Transposase
JCP66_RS14450 () 61910..62092 - 183 WP_002300846.1 hypothetical protein -
JCP66_RS14455 () 62333..62551 + 219 Protein_66 IS256 family transposase ISLgar5 Transposase
JCP66_RS14460 () 63046..63645 + 600 WP_002301839.1 Tyrosine recombinase XerD VF
JCP66_RS14465 () 63709..64308 + 600 WP_002322465.1 bacteriophage abortive infection AbiH family protein -
JCP66_RS14470 () 64338..64989 - 652 Protein_69 IS6 family transposase IS1216V Transposase
JCP66_RS14475 () 65324..66196 - 873 WP_002305879.1 ROK family protein -
JCP66_RS14480 () 66460..68406 - 1947 WP_002352509.1 sucrose-specific PTS transporter subunit IIBC -
JCP66_RS14485 () 68591..70030 + 1440 WP_002302078.1 sucrose-6-phosphate hydrolase -
JCP66_RS14490 () 70032..70994 + 963 WP_002302077.1 LacI family DNA-binding transcriptional regulator -
JCP66_RS14500 () 72833..73288 + 456 WP_002301718.1 IS200-IS605 family transposase ISAac3 Transposase
JCP66_RS14505 () 73553..73651 + 99 Protein_76 IS30 family transposase -
JCP66_RS14510 () 73874..74104 - 231 WP_002289255.1 resolvase -
JCP66_RS14515 () 74334..75152 - 819 WP_002289254.1 MurR/RpiR family transcriptional regulator -
JCP66_RS14520 () 75313..76002 + 690 WP_002289253.1 N-acetylmannosamine-6-phosphate 2-epimerase -
JCP66_RS14525 () 76016..77518 + 1503 WP_002289252.1 PTS transporter subunit EIIC -
JCP66_RS14530 () 77531..78007 + 477 WP_002300328.1 PTS glucose transporter subunit IIA -
JCP66_RS14535 () 78104..78214 - 111 Protein_82 transposase -
JCP66_RS14545 () 80785..81303 + 519 WP_002287870.1 ClbS/DfsB family four-helix bundle protein -
JCP66_RS14550 () 82440..82847 - 408 WP_002329899.1 type II toxin-antitoxin system death-on-curing family toxin -
JCP66_RS14555 () 82844..83077 - 234 WP_002290351.1 addiction module antitoxin -
JCP66_RS14560 () 83411..84496 + 1086 WP_002290352.1 tyrosine recombinase XerS -
JCP66_RS14565 () 84780..85445 - 666 WP_002324528.1 site-specific integrase -
JCP66_RS14570 () 85599..85748 - 150 WP_002290356.1 hypothetical protein -
JCP66_RS14575 () 85741..85950 - 210 WP_002290357.1 DUF3173 domain-containing protein -
JCP66_RS14580 () 86272..87378 - 1107 Protein_91 IS4 family transposase IS641 Transposase
JCP66_RS14585 () 87455..88915 - 1461 WP_002335326.1 sucrose phosphorylase -
JCP66_RS14590 () 88912..90132 - 1221 WP_002342361.1 hypothetical protein -
JCP66_RS14595 () 90193..92376 - 2184 WP_002290367.1 alpha-galactosidase -
JCP66_RS14600 () 92416..93246 - 831 WP_002290368.1 carbohydrate ABC transporter permease -
JCP66_RS14605 () 93258..94130 - 873 WP_002290370.1 sugar ABC transporter permease -
JCP66_RS14610 () 94140..95399 - 1260 WP_002290371.1 extracellular solute-binding protein -
JCP66_RS14615 () 95547..96857 - 1311 WP_002329911.1 alpha-glucosidase/alpha-galactosidase -
JCP66_RS14620 () 96889..97713 - 825 WP_002350071.1 carbohydrate ABC transporter permease -
JCP66_RS14625 () 97729..98625 - 897 Protein_100 sugar ABC transporter permease -
JCP66_RS14630 () 98708..99817 - 1110 WP_002350067.1 sugar ABC transporter substrate-binding protein -
JCP66_RS14635 () 100111..101136 - 1026 WP_002338088.1 LacI family DNA-binding transcriptional regulator -
JCP66_RS14640 () 101381..102652 - 1272 WP_002290379.1 substrate-binding domain-containing protein -
JCP66_RS14645 () 102936..103883 - 948 Protein_104 VOC family protein -
JCP66_RS14650 () 103895..104368 + 474 WP_002290382.1 IS91 family transposase ISCARN110 Transposase
JCP66_RS14655 () 104541..105095 - 555 WP_002290383.1 tyrosine-type recombinase/integrase -
JCP66_RS14660 () 105568..106737 - 1170 WP_002300314.1 IS256 family transposase ISEfa13 Transposase
JCP66_RS14665 () 107757..108374 - 618 WP_002319325.1 hypothetical protein -
JCP66_RS14670 () 108436..109116 - 681 Protein_109 IS6 family transposase IS1297 Transposase
JCP66_RS14675 () 109438..109659 - 222 WP_002311006.1 hypothetical protein -
JCP66_RS14680 () 109757..110002 - 246 WP_008271463.1 hypothetical protein -
JCP66_RS14685 () 110242..110856 + 615 Protein_112 Tn3 family transposase TnBth3 Transposase
JCP66_RS14690 () 111226..112227 - 1002 WP_002344895.1 DUF4062 domain-containing protein -
JCP66_RS14695 () 112386..112652 - 267 WP_002344896.1 helix-turn-helix transcriptional regulator -
JCP66_RS14700 () 112642..112998 - 357 WP_002344897.1 type II toxin-antitoxin system RelE/ParE family toxin -
JCP66_RS14705 () 113133..113813 + 681 WP_001015311.1 IS6 family transposase IS1216E Transposase
JCP66_RS14710 () 114601..114927 - 327 Protein_117 2-dehydro-3-deoxyphosphogluconate aldolase -
JCP66_RS14715 () 114972..115652 - 681 Protein_118 IS6 family transposase IS1297 Transposase
JCP66_RS14720 () 115727..116022 - 296 Protein_119 hypothetical protein -
JCP66_RS14725 () 116282..116830 - 549 WP_002292681.1 hypothetical protein -
JCP66_RS14730 () 116831..117688 - 858 WP_002292680.1 AAA family ATPase -
JCP66_RS14735 () 117974..118260 - 287 Protein_122 type II toxin-antitoxin system RelE/ParE family toxin -
JCP66_RS14740 () 118250..118579 - 330 WP_002292678.1 AbrB family transcriptional regulator -
JCP66_RS14745 () 118728..119408 - 681 Protein_124 IS6 family transposase IS1216V Transposase
JCP66_RS14750 () 119482..119763 - 282 Protein_125 YfbU family protein -
JCP66_RS14755 () 120225..121607 + 1383 Protein_126 IS3 family transposase ISLca1 Transposase
JCP66_RS14760 () 121843..122715 - 873 WP_060811653.1 ROK family protein -
JCP66_RS14765 () 122732..124204 - 1473 WP_002322556.1 glycoside hydrolase family 32 protein -
JCP66_RS14770 () 124218..125066 - 849 WP_002313079.1 carbohydrate ABC transporter permease -
JCP66_RS14775 () 125063..125929 - 867 WP_002322555.1 sugar ABC transporter permease -
JCP66_RS14780 () 125972..127285 - 1314 WP_002313081.1 sugar ABC transporter substrate-binding protein -
JCP66_RS14785 () 127425..128396 - 972 WP_010729506.1 LacI family DNA-binding transcriptional regulator -
JCP66_RS14790 () 128522..128749 - 228 Protein_133 IS110 family transposase -
JCP66_RS14795 () 128914..129249 - 336 Protein_134 Tn3 family transposase TnpA_ISXc4 Transposase
JCP66_RS14800 () 129431..130036 + 606 WP_002313084.1 Tn3 family transposase TnpR_ISPa40 Transposase
JCP66_RS14805 () 130748..130948 - 201 Protein_136 hypothetical protein -
JCP66_RS14810 () 131155..131364 - 210 WP_002348862.1 hypothetical protein -
JCP66_RS14815 () 131425..132384 - 960 WP_002336308.1 IS30 family transposase IS1062 Transposase
JCP66_RS14820 () 132552..132823 - 272 Protein_139 HAD-IA family hydrolase -
JCP66_RS14825 () 132934..133842 + 909 WP_010729754.1 IS982 family transposase ISEfm1 Transposase
JCP66_RS14830 () 133901..135703 - 1803 WP_010729753.1 3'-5' exoribonuclease -
JCP66_RS14835 () 135766..136608 - 843 WP_002342384.1 hypothetical protein -
JCP66_RS14840 () 136624..136845 - 222 WP_002331328.1 helix-turn-helix transcriptional regulator -
JCP66_RS14845 () 136988..137266 - 279 Protein_144 site-specific recombinase -
JCP66_RS14850 () 137341..138021 + 681 WP_002336713.1 IS6 family transposase IS1216E Transposase
JCP66_RS14855 () 138079..139299 - 1221 WP_002339142.1 PAS domain-containing protein -
JCP66_RS14860 () 139319..139930 - 612 WP_002339141.1 NAD(P)H-dependent oxidoreductase -
JCP66_RS14865 () 139973..140905 - 933 WP_002350224.1 FAD:protein FMN transferase -
JCP66_RS14870 () 141326..142186 - 861 WP_002350223.1 helix-turn-helix domain-containing protein -
JCP66_RS14875 () 142318..142998 - 681 WP_001015311.1 IS6 family transposase IS1216E Transposase
JCP66_RS14880 () 143074..143286 + 213 Protein_151 transposase -
JCP66_RS14885 () 143416..144291 - 876 WP_063610281.1 aminoglycoside O-phosphotransferase APH(2'')-Ia -
JCP66_RS14890 () 144573..144953 - 381 Protein_153 IS6 family transposase IS1216V Transposase
JCP66_RS14895 () 145023..145703 + 681 WP_002319817.1 IS6 family transposase IS1297 Transposase
JCP66_RS14900 () 145709..146179 + 471 WP_010729776.1 Tn3 family transposase TnpR_ISPa40 Transposase
JCP66_RS14905 () 146224..146391 - 168 WP_000824191.1 hypothetical protein -
JCP66_RS14910 () 146425..146724 - 300 WP_000366408.1 BRCT domain-containing protein -
JCP66_RS14915 () 146765..147382 - 618 WP_001224538.1 Tn3 family transposase TnpR_TnAs2 Transposase
JCP66_RS14920 () 147707..148102 - 396 WP_002304891.1 hypothetical protein -
JCP66_RS14925 () 148182..150533 - 2352 WP_000344083.1 DUF1906 domain-containing protein -
JCP66_RS14930 () 150658..151347 - 690 WP_000718009.1 hypothetical protein -
JCP66_RS14935 () 151361..151813 - 453 WP_000751236.1 hypothetical protein -
JCP66_RS14945 () 153300..153980 + 681 WP_001015311.1 IS6 family transposase IS1216E Transposase
JCP66_RS14950 () 154082..155401 - 1320 WP_002300494.1 HAMP domain-containing histidine kinase -
JCP66_RS14955 () 155398..156051 - 654 WP_002285815.1 Transcriptional regulatory protein QseB VF
JCP66_RS14960 () 156339..156859 + 521 Protein_167 transposase -
JCP66_RS14965 () 156761..157477 - 717 WP_002348630.1 aminotransferase class V-fold PLP-dependent enzyme -
JCP66_RS14970 () 157527..157736 - 210 WP_002302256.1 hypothetical protein -
JCP66_RS14975 () 158013..159286 + 1274 Protein_170 ISL3 family transposase ISEfa11 Transposase
JCP66_RS14980 () 159393..160424 - 1032 WP_002302261.1 Spermidine/putrescine import ATP-binding protein PotA VF
JCP66_RS14985 () 160431..161261 - 831 WP_002313180.1 ABC transporter permease -
JCP66_RS14990 () 161258..162073 - 816 WP_002330693.1 ABC transporter permease subunit -
JCP66_RS14995 () 162070..162894 - 825 WP_002302267.1 alkaline phosphatase family protein -
JCP66_RS15000 () 162884..163984 - 1101 WP_002302268.1 extracellular solute-binding protein -
JCP66_RS15005 () 164162..164947 + 786 WP_002302270.1 histidinol phosphate phosphatase -
JCP66_RS15010 () 164980..165363 + 384 WP_002330694.1 hypothetical protein -
JCP66_RS15015 () 165439..165570 + 132 WP_077828694.1 peptidylprolyl isomerase -
JCP66_RS15020 () 165539..165775 + 237 WP_002322470.1 Putative bifunctional phosphatase/peptidyl-prolyl cis-trans isomerase VF
JCP66_RS15025 () 165853..166824 - 972 WP_002302275.1 radical SAM protein -
JCP66_RS15030 () 167476..169098 + 1623 WP_049142603.1 IS1182 family transposase ISEfa7 Transposase
JCP66_RS15035 () 169384..170760 - 1377 WP_002301195.1 ABC transporter permease -
JCP66_RS15040 () 170760..171416 - 657 WP_002298083.1 putative ABC transporter ATP-binding protein VF
JCP66_RS15045 () 171426..172703 - 1278 WP_002301194.1 ABC transporter permease -
JCP66_RS15050 () 172722..172877 - 156 Protein_185 4Fe-4S binding protein -
JCP66_RS15055 () 172953..174115 + 1163 WP_087121905.1 IS3 family transposase ISEfa8 Transposase
JCP66_RS15060 () 174145..174594 - 450 WP_010729386.1 TlpA family protein disulfide reductase -
JCP66_RS15065 () 174750..175292 - 543 WP_002298088.1 hypothetical protein -
JCP66_RS15070 () 175567..176210 + 644 Protein_189 transposase -
JCP66_RS15075 () 176286..176966 + 681 WP_002331383.1 IS6 family transposase IS1216E Transposase
JCP66_RS15080 () 177025..177213 - 189 Protein_191 hypothetical protein -
JCP66_RS15085 () 177214..178071 - 858 WP_002292680.1 AAA family ATPase -
JCP66_RS15090 () 178357..178643 - 287 Protein_193 type II toxin-antitoxin system RelE/ParE family toxin -
JCP66_RS15095 () 178633..178962 - 330 WP_002292678.1 AbrB family transcriptional regulator -
JCP66_RS15100 () 179039..179311 - 273 WP_002314366.1 Txe/YoeB family addiction module toxin Toxin Detail
JCP66_RS15105 () 179311..179574 - 264 WP_002297422.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin Detail
JCP66_RS15110 () 179808..180716 + 909 Protein_197 IS982 family transposase ISEfm1 Transposase
JCP66_RS15115 () 180719..181894 - 1176 WP_002336205.1 MFS transporter -
JCP66_RS15120 () 181897..184146 - 2250 WP_002314387.1 alpha-galactosidase -
JCP66_RS15125 () 184243..185097 - 855 WP_002338109.1 AraC family transcriptional regulator -
JCP66_RS15130 () 185179..186087 - 909 Protein_201 IS982 family transposase ISEfm1 Transposase
JCP66_RS15135 () 186181..187116 - 936 WP_002323400.1 hypothetical protein -
JCP66_RS15140 () 187675..187992 - 318 WP_002290394.1 type II toxin-antitoxin system RelE/ParE family toxin -
JCP66_RS15145 () 187993..188247 - 255 WP_002323399.1 hypothetical protein -
JCP66_RS15150 () 188606..189010 + 405 WP_002287522.1 IS200-IS605 family transposase ISEfa4 Transposase
JCP66_RS15155 () 189027..190175 + 1149 WP_002323589.1 IS200-IS605 family transposase ISEfa4 Transposase
JCP66_RS15160 () 190398..190616 - 219 Protein_207 type II toxin-antitoxin system RelE/ParE family toxin -
JCP66_RS15165 () 190882..191076 - 195 WP_002348857.1 hypothetical protein -
JCP66_RS15170 () 191176..191262 - 87 Protein_209 single-stranded DNA-binding protein -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance