NZ_CP0657681..141428

MGE detailed information

MGE type: Non-Mobilizable plasmid        MGE length: 141428 bp
Accession: NZ_CP065768        Location: 1..141428         Organism: Enterococcus faecium strain 17-508       Replicon: plasmid p17-508_1


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I8F56_RS13220 (I8F56_13220) 1..1041 + 1041 WP_002322487.1 replication initiator protein A -
I8F56_RS13225 (I8F56_13225) 1879..2211 + 333 WP_002322486.1 type IV conjugative transfer system protein TraE -
I8F56_RS14315 2830..3171 + 342 Protein_2 DUF5406 domain-containing protein -
I8F56_RS14320 3190..3312 + 123 WP_002293478.1 hypothetical protein -
I8F56_RS13240 (I8F56_13240) 3338..3577 + 240 WP_002347362.1 hypothetical protein -
I8F56_RS13245 (I8F56_13245) 3643..3882 + 240 WP_002322851.1 hypothetical protein -
I8F56_RS13255 (I8F56_13255) 4237..4886 + 650 Protein_6 EpaQ family protein -
I8F56_RS13260 (I8F56_13260) 4968..5639 + 672 WP_002375749.1 class A sortase -
I8F56_RS13265 (I8F56_13265) 5692..7668 + 1977 WP_010724687.1 SpaA isopeptide-forming pilin-related protein -
I8F56_RS13270 (I8F56_13270) 7683..8435 + 753 WP_002318303.1 hypothetical protein VF
I8F56_RS13275 (I8F56_13275) 8451..9206 + 756 WP_010724688.1 pilin N-terminal domain-containing protein -
I8F56_RS13280 (I8F56_13280) 9219..9479 + 261 WP_002314405.1 hypothetical protein -
I8F56_RS13285 (I8F56_13285) 9476..11566 + 2091 WP_010724689.1 isopeptide-forming domain-containing fimbrial protein -
I8F56_RS13290 (I8F56_13290) 11593..12057 + 465 WP_002310966.1 hypothetical protein -
I8F56_RS13295 (I8F56_13295) 12054..12296 + 243 WP_010724690.1 DUF5415 family protein -
I8F56_RS13300 (I8F56_13300) 12314..12616 + 303 WP_002295662.1 hypothetical protein -
I8F56_RS13305 (I8F56_13305) 12686..14761 + 2076 WP_002375739.1 hypothetical protein -
I8F56_RS13310 (I8F56_13310) 14761..17370 + 2610 WP_200774105.1 type IV secretory system conjugative DNA transfer family protein -
I8F56_RS13315 (I8F56_13315) 17367..19739 + 2373 WP_214359283.1 hypothetical protein -
I8F56_RS13320 (I8F56_13320) 19791..20123 + 333 WP_002295656.1 hypothetical protein -
I8F56_RS13325 (I8F56_13325) 20124..20717 + 594 WP_002307538.1 hypothetical protein -
I8F56_RS13330 (I8F56_13330) 20880..22904 + 2025 WP_002307536.1 ATPase -
I8F56_RS13335 (I8F56_13335) 22904..24121 + 1218 WP_002333391.1 glucosaminidase domain-containing protein -
I8F56_RS13340 (I8F56_13340) 24137..24781 + 645 WP_002333392.1 hypothetical protein -
I8F56_RS13345 (I8F56_13345) 24792..25598 + 807 WP_002333393.1 hypothetical protein -
I8F56_RS13350 (I8F56_13350) 25621..25851 + 231 WP_002333394.1 hypothetical protein -
I8F56_RS13355 (I8F56_13355) 26366..26662 + 297 WP_002293513.1 hypothetical protein -
I8F56_RS13360 (I8F56_13360) 26664..27086 + 423 WP_002295642.1 hypothetical protein -
I8F56_RS13365 (I8F56_13365) 27105..28697 + 1593 WP_033607013.1 hypothetical protein Relaxase
I8F56_RS13370 (I8F56_13370) 28709..29044 + 336 WP_002310991.1 hypothetical protein -
I8F56_RS13375 (I8F56_13375) 29190..29384 + 195 WP_010724693.1 hypothetical protein -
I8F56_RS13380 (I8F56_13380) 29520..30770 - 1251 WP_002287107.1 IS110 family transposase ISSpn10 Transposase
I8F56_RS13385 (I8F56_13385) 31180..33552 + 2373 WP_002333396.1 ArdC-like ssDNA-binding domain-containing protein -
I8F56_RS13390 (I8F56_13390) 33613..35073 + 1461 WP_002328865.1 toprim domain-containing protein -
I8F56_RS13395 (I8F56_13395) 35084..37288 + 2205 Protein_34 DNA topoisomerase III -
I8F56_RS13400 (I8F56_13400) 37304..37453 + 150 WP_002328868.1 hypothetical protein -
I8F56_RS13405 (I8F56_13405) 37534..38130 + 597 WP_002299811.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein -
I8F56_RS13410 (I8F56_13410) 38143..39042 + 900 WP_002301800.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
I8F56_RS13415 (I8F56_13415) 39045..39518 + 474 Protein_38 single-stranded DNA-binding protein -
I8F56_RS13420 (I8F56_13420) 39540..39797 + 258 WP_002295625.1 hypothetical protein -
I8F56_RS13425 (I8F56_13425) 39956..40100 - 145 Protein_40 putative holin-like toxin -
I8F56_RS13430 (I8F56_13430) 40233..40493 + 261 WP_002316757.1 hypothetical protein -
I8F56_RS13435 (I8F56_13435) 40937..41146 + 210 WP_002316758.1 hypothetical protein -
I8F56_RS13440 (I8F56_13440) 41143..41394 + 252 WP_002314430.1 hypothetical protein -
I8F56_RS13445 (I8F56_13445) 41410..41847 + 438 WP_002311567.1 hypothetical protein -
I8F56_RS13450 (I8F56_13450) 42283..42453 + 171 WP_002293544.1 hypothetical protein -
I8F56_RS13455 (I8F56_13455) 42528..42923 + 396 WP_002293546.1 hypothetical protein -
I8F56_RS13460 (I8F56_13460) 42965..43171 + 207 WP_002328873.1 hypothetical protein -
I8F56_RS13465 (I8F56_13465) 43181..43414 + 234 WP_002307516.1 DUF2786 domain-containing protein -
I8F56_RS13470 (I8F56_13470) 43757..43939 + 183 WP_002335346.1 leucocin A/sakacin P family class II bacteriocin -
I8F56_RS13475 (I8F56_13475) 43929..44240 + 312 WP_002336187.1 hypothetical protein -
I8F56_RS13480 (I8F56_13480) 44400..45308 + 909 WP_002295743.1 IS982 family transposase ISEfm1 Transposase
I8F56_RS13485 (I8F56_13485) 45364..45861 + 498 WP_002295755.1 GNAT family N-acetyltransferase -
I8F56_RS13490 (I8F56_13490) 45898..46593 - 696 WP_002328878.1 PHP domain-containing protein -
I8F56_RS13495 (I8F56_13495) 46889..47191 - 303 WP_002314435.1 hypothetical protein -
I8F56_RS13500 (I8F56_13500) 47249..48208 + 960 WP_002314436.1 IS30 family transposase IS6770 Transposase
I8F56_RS13505 (I8F56_13505) 48645..49823 + 1179 WP_002340536.1 IS256 family transposase ISEfm2 Transposase
I8F56_RS13510 (I8F56_13510) 49985..51415 + 1431 WP_002336208.1 hypothetical protein -
I8F56_RS13515 (I8F56_13515) 51412..52035 - 624 WP_002328880.1 Tn3 family transposase TnpR_TnAs2 Transposase
I8F56_RS13520 (I8F56_13520) 52311..52691 + 381 Protein_59 Tn3 family transposase TnpR_ISMex38 Transposase
I8F56_RS13525 (I8F56_13525) 52783..53488 + 706 Protein_60 DNA topoisomerase -
I8F56_RS13530 (I8F56_13530) 53565..54727 + 1163 WP_086956687.1 IS3 family transposase IS1485 Transposase
I8F56_RS13535 (I8F56_13535) 54757..55515 - 759 WP_002333400.1 HAD family hydrolase -
I8F56_RS13540 (I8F56_13540) 55520..56287 - 768 WP_002290556.1 DeoR/GlpR family DNA-binding transcription regulator -
I8F56_RS13545 (I8F56_13545) 56776..57201 + 426 WP_002290555.1 galactose-6-phosphate isomerase subunit LacA -
I8F56_RS13550 (I8F56_13550) 57218..57733 + 516 WP_002290554.1 galactose-6-phosphate isomerase subunit LacB -
I8F56_RS13555 (I8F56_13555) 57744..58676 + 933 WP_002290553.1 tagatose-6-phosphate kinase -
I8F56_RS13560 (I8F56_13560) 58679..59659 + 981 WP_002290551.1 tagatose-bisphosphate aldolase -
I8F56_RS13565 (I8F56_13565) 59687..60004 + 318 WP_002290550.1 PTS lactose/cellobiose transporter subunit IIA -
I8F56_RS13570 (I8F56_13570) 60004..61710 + 1707 WP_002290549.1 lactose-specific PTS transporter subunit EIIC -
I8F56_RS13575 (I8F56_13575) 61852..63258 + 1407 WP_002333401.1 6-phospho-beta-galactosidase -
I8F56_RS14325 63281..63554 + 274 Protein_71 DUF3884 family protein -
I8F56_RS13585 (I8F56_13585) 63575..64474 + 900 WP_002337617.1 aldose 1-epimerase family protein -
I8F56_RS13595 (I8F56_13595) 66687..67574 - 888 WP_002316080.1 exonuclease domain-containing protein -
I8F56_RS13600 (I8F56_13600) 67768..68448 - 681 WP_000191454.1 IS6 family transposase ISEnfa1 Transposase
I8F56_RS13605 (I8F56_13605) 68487..68651 - 165 WP_001808810.1 helix-turn-helix transcriptional regulator -
I8F56_RS13610 (I8F56_13610) 68688..69014 + 327 WP_002387760.1 DNA-binding protein -
I8F56_RS13615 (I8F56_13615) 69004..69618 + 615 WP_000395511.1 bacitracin resistance transcriptional activator BcrR -
I8F56_RS13620 (I8F56_13620) 69801..70718 + 918 WP_002346952.1 ATP-binding cassette domain-containing protein -
I8F56_RS13625 (I8F56_13625) 70711..71460 + 750 WP_000933358.1 ABC transporter permease -
I8F56_RS13630 (I8F56_13630) 71460..72290 + 831 WP_000242080.1 undecaprenyl-diphosphate phosphatase -
I8F56_RS13635 (I8F56_13635) 72487..73167 - 681 WP_000191454.1 IS6 family transposase ISEnfa1 Transposase
I8F56_RS13640 (I8F56_13640) 73217..73693 - 477 WP_010724676.1 S24 family peptidase -
I8F56_RS13645 (I8F56_13645) 73656..73892 + 237 WP_002308077.1 helix-turn-helix transcriptional regulator -
I8F56_RS13650 (I8F56_13650) 74128..76242 + 2115 WP_002308075.1 putative ATP-dependent Clp protease ATP-binding subunit VF
I8F56_RS13655 (I8F56_13655) 76423..76737 - 315 Protein_86 transposase -
I8F56_RS13660 (I8F56_13660) 76810..77046 + 237 WP_002308029.1 hypothetical protein -
I8F56_RS13665 (I8F56_13665) 77265..77456 + 192 WP_002314345.1 hypothetical protein -
I8F56_RS14330 77974..78384 + 411 WP_002316999.1 hypothetical protein -
I8F56_RS13670 (I8F56_13670) 78444..79319 + 876 WP_002336211.1 primase C-terminal domain-containing protein -
I8F56_RS13675 (I8F56_13675) 79363..79557 + 195 WP_002311030.1 hypothetical protein -
I8F56_RS13680 (I8F56_13680) 79571..79711 + 141 WP_002316998.1 hypothetical protein -
I8F56_RS14335 79725..81094 + 1370 Protein_93 DNA topoisomerase -
I8F56_RS14340 81266..81529 + 264 WP_223610958.1 topoisomerase C-terminal repeat-containing protein -
I8F56_RS13695 (I8F56_13695) 81940..82128 + 189 WP_002311028.1 hypothetical protein -
I8F56_RS13700 (I8F56_13700) 82853..83275 + 423 WP_002307506.1 cupin domain-containing protein -
I8F56_RS13705 (I8F56_13705) 83359..84012 + 654 WP_002307505.1 putative iron export ATP-binding protein FetA VF
I8F56_RS13710 (I8F56_13710) 84009..84773 + 765 WP_002311027.1 iron export ABC transporter permease subunit FetB -
I8F56_RS13715 (I8F56_13715) 85184..85420 + 237 WP_002356094.1 DUF302 domain-containing protein -
I8F56_RS14345 85447..85630 - 184 Protein_100 recombinase family protein -
I8F56_RS13720 (I8F56_13720) 85890..86489 + 600 WP_002301839.1 Tyrosine recombinase XerD VF
I8F56_RS13725 (I8F56_13725) 86553..87452 + 900 WP_002311023.1 AbiH family protein -
I8F56_RS13730 (I8F56_13730) 88391..89266 + 876 WP_002337613.1 hypothetical protein -
I8F56_RS13735 (I8F56_13735) 89378..89752 + 375 WP_225596504.1 hypothetical protein -
I8F56_RS13740 (I8F56_13740) 89996..91321 + 1326 WP_010724677.1 Y-family DNA polymerase -
I8F56_RS13745 (I8F56_13745) 91314..91664 + 351 WP_002290348.1 hypothetical protein -
I8F56_RS13750 (I8F56_13750) 91805..92314 + 510 WP_002295345.1 hypothetical protein -
I8F56_RS13755 (I8F56_13755) 92765..93172 - 408 WP_002307501.1 type II toxin-antitoxin system death-on-curing family toxin -
I8F56_RS13760 (I8F56_13760) 93169..93402 - 234 WP_002295764.1 addiction module antitoxin -
I8F56_RS13765 (I8F56_13765) 93724..94809 + 1086 WP_002295762.1 tyrosine recombinase XerS -
I8F56_RS13770 (I8F56_13770) 94872..95426 - 555 WP_002295761.1 tyrosine-type recombinase/integrase -
I8F56_RS13775 (I8F56_13775) 95900..97078 - 1179 WP_002340536.1 IS256 family transposase ISEfm2 Transposase
I8F56_RS13780 (I8F56_13780) 98099..98584 - 486 WP_080114350.1 hypothetical protein -
I8F56_RS13785 (I8F56_13785) 98660..99340 - 681 WP_002328842.1 IS6 family transposase IS1297 Transposase
I8F56_RS13790 (I8F56_13790) 99674..100567 + 894 WP_002316719.1 neutral zinc metallopeptidase -
I8F56_RS13800 (I8F56_13800) 101107..102392 + 1286 Protein_116 cytochrome P450 -
I8F56_RS13805 (I8F56_13805) 102464..104089 - 1626 WP_002331388.1 peptide ABC transporter substrate-binding protein -
I8F56_RS13810 (I8F56_13810) 104580..105029 + 450 WP_002331389.1 DIP1984 family protein -
I8F56_RS13815 (I8F56_13815) 105346..105927 - 582 WP_002331293.1 IS630 family transposase ISBs2 Transposase
I8F56_RS13820 (I8F56_13820) 105946..107289 - 1344 WP_002332322.1 PFL family protein -
I8F56_RS13825 (I8F56_13825) 107304..107570 - 267 WP_002290085.1 ACT domain-containing protein -
I8F56_RS13830 (I8F56_13830) 107673..108341 - 669 WP_002331291.1 2,3-diphosphoglycerate-dependent phosphoglycerate mutase -
I8F56_RS13835 (I8F56_13835) 108623..109483 + 861 Protein_123 MATE family efflux transporter -
I8F56_RS13840 (I8F56_13840) 109483..110097 - 615 Protein_124 PTS beta-glucoside transporter subunit IIBC -
I8F56_RS13845 (I8F56_13845) 110117..110359 - 243 WP_002331325.1 PTS sugar transporter subunit IIB -
I8F56_RS13850 (I8F56_13850) 110464..110679 - 216 Protein_126 DDE-type integrase/transposase/recombinase -
I8F56_RS13855 (I8F56_13855) 110844..111626 - 783 WP_002331326.1 hypothetical protein -
I8F56_RS13860 (I8F56_13860) 111859..113661 - 1803 WP_002331327.1 exonuclease domain-containing protein -
I8F56_RS14350 113724..114209 - 486 WP_227326759.1 hypothetical protein -
I8F56_RS13870 (I8F56_13870) 114582..114803 - 222 WP_002331328.1 helix-turn-helix transcriptional regulator -
I8F56_RS13875 (I8F56_13875) 114946..115275 - 330 Protein_131 recombinase family protein -
I8F56_RS13880 (I8F56_13880) 115351..116031 + 681 WP_053109539.1 IS6 family transposase IS1216E Transposase
I8F56_RS13885 (I8F56_13885) 116065..116238 - 174 WP_229214455.1 hypothetical protein -
I8F56_RS13890 (I8F56_13890) 116250..116987 - 738 WP_002331331.1 S8 family serine peptidase -
I8F56_RS13895 (I8F56_13895) 117247..117795 - 549 WP_002292681.1 hypothetical protein -
I8F56_RS13900 (I8F56_13900) 117796..118653 - 858 WP_002292680.1 ParA family protein -
I8F56_RS13905 (I8F56_13905) 118939..119226 - 288 WP_002300557.1 type II toxin-antitoxin system RelE/ParE family toxin -
I8F56_RS13910 (I8F56_13910) 119216..119545 - 330 WP_002292678.1 AbrB family transcriptional regulator -
I8F56_RS13915 (I8F56_13915) 119622..119894 - 273 WP_002305108.1 Txe/YoeB family addiction module toxin Toxin Detail
I8F56_RS13920 (I8F56_13920) 119894..120157 - 264 WP_002303154.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin Detail
I8F56_RS13925 (I8F56_13925) 120263..120586 - 324 WP_229214454.1 hypothetical protein -
I8F56_RS13930 (I8F56_13930) 120685..121248 - 564 Protein_142 IS6 family transposase IS1297 Transposase
I8F56_RS13935 (I8F56_13935) 121328..122490 + 1163 WP_086956687.1 IS3 family transposase IS1485 Transposase
I8F56_RS13940 (I8F56_13940) 122634..123071 - 438 WP_002307485.1 universal stress protein -
I8F56_RS13945 (I8F56_13945) 123080..124687 - 1608 WP_010724683.1 Nramp family divalent metal transporter -
I8F56_RS13950 (I8F56_13950) 124854..125762 - 909 WP_016925867.1 IS982 family transposase ISEfm1 Transposase
I8F56_RS13955 (I8F56_13955) 126088..126252 + 165 WP_002298900.1 leucocin A/sakacin P family class II bacteriocin -
I8F56_RS13960 (I8F56_13960) 126262..126570 + 309 WP_010724685.1 hypothetical protein -
I8F56_RS13965 (I8F56_13965) 126873..129140 + 2268 WP_002335316.1 excinuclease ABC subunit UvrA -
I8F56_RS13970 (I8F56_13970) 129285..129454 - 170 Protein_150 recombinase family protein -
I8F56_RS13975 (I8F56_13975) 129582..130085 + 504 WP_214359282.1 type 1 glutamine amidotransferase domain-containing protein -
I8F56_RS13980 (I8F56_13980) 130454..131616 + 1163 WP_086956687.1 IS3 family transposase IS1485 Transposase
I8F56_RS13985 (I8F56_13985) 131722..132653 - 932 Protein_153 IS30 family transposase ISLpl1 Transposase
I8F56_RS13990 (I8F56_13990) 132946..134202 + 1257 WP_002307470.1 OFA family MFS transporter -
I8F56_RS14000 (I8F56_14000) 134954..135474 + 521 Protein_155 type I restriction endonuclease -
I8F56_RS14005 (I8F56_14005) 135604..136449 + 846 WP_002335312.1 aldo/keto reductase -
I8F56_RS14010 (I8F56_14010) 136660..136800 + 141 WP_002335311.1 hypothetical protein -
I8F56_RS14015 (I8F56_14015) 136782..137054 + 273 Protein_158 restriction endonuclease subunit S -
I8F56_RS14020 (I8F56_14020) 137108..137788 - 681 WP_001015311.1 IS6 family transposase IS1216E Transposase
I8F56_RS14025 (I8F56_14025) 137864..138076 - 213 Protein_160 IS6 family transposase IS1216E Transposase
I8F56_RS14030 (I8F56_14030) 138589..138906 - 318 WP_002375762.1 type II toxin-antitoxin system RelE/ParE family toxin -
I8F56_RS14035 (I8F56_14035) 138907..139161 - 255 WP_002290397.1 AbrB family transcriptional regulator -
I8F56_RS14355 139421..139561 - 141 WP_002290398.1 hypothetical protein -
I8F56_RS14045 (I8F56_14045) 140196..140282 - 87 Protein_164 single-stranded DNA-binding protein -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance