MGE detailed information

MGE type: Non-Mobilizable plasmid        MGE length: 183887 bp
Accession: NZ_CP061390        Location: 1..183887         Organism: Klebsiella pneumoniae strain NU-CRE195       Replicon: plasmid pCRE-195-1


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HCV84_RS26510 () 1..1011 + 1011 WP_004182030.1 RepB family plasmid replication initiator protein -
HCV84_RS26515 () 1729..2469 - 741 WP_001515717.1 tyrosine-type recombinase/integrase -
HCV84_RS26520 () 3613..4560 + 948 WP_004182028.1 sensor domain-containing diguanylate cyclase -
HCV84_RS26525 () 4587..4898 - 312 WP_071527918.1 EAL domain-containing protein -
HCV84_RS26530 () 4918..5886 + 969 WP_068814619.1 IS5 family transposase IS903B Transposase
HCV84_RS26535 () 6559..6816 - 258 WP_004197688.1 hypothetical protein -
HCV84_RS26540 () 7436..8872 + 1437 WP_080895248.1 putative cyclic di-GMP phosphodiesterase PdeB VF
HCV84_RS26545 () 9855..11132 - 1278 WP_004152070.1 DUF2254 domain-containing protein -
HCV84_RS26550 () 11195..13192 - 1998 WP_004178088.1 choline BCCT transporter BetT -
HCV84_RS26555 () 13344..14041 - 698 Protein_9 IS1 family transposase IS1X3 Transposase
HCV84_RS26565 () 15530..16014 + 485 Protein_11 IS1 family transposase IS1X2 Transposase
HCV84_RS26570 () 16030..16572 + 543 Protein_12 ISL3 family transposase ISKpn25 Transposase
HCV84_RS26575 () 16868..17299 - 432 WP_004178091.1 silver-binding protein SilE -
HCV84_RS26580 () 17550..19025 - 1476 WP_003032875.1 copper/silver sensor histidine kinase SilS -
HCV84_RS26585 () 19018..19698 - 681 WP_001572351.1 Transcriptional regulatory protein CusR VF
HCV84_RS26590 () 19888..21273 + 1386 WP_004182016.1 Cation efflux system protein CusC VF
HCV84_RS26595 () 21302..21655 + 354 WP_001246153.1 cation efflux system protein CusF -
HCV84_RS26600 () 21769..23061 + 1293 WP_004098959.1 Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB -
HCV84_RS26605 () 23072..26218 + 3147 WP_004098958.1 Cu(+)/Ag(+) efflux RND transporter permease subunit SilA -
HCV84_RS26610 () 26305..26745 + 441 WP_000758228.1 hypothetical protein -
HCV84_RS26615 () 26872..29319 + 2448 WP_004098955.1 Ag(+)-translocating P-type ATPase SilP -
HCV84_RS26620 () 29360..29557 + 198 WP_000843497.1 DUF2933 domain-containing protein -
HCV84_RS26625 () 29591..30328 - 738 WP_004182013.1 Murein DD-endopeptidase MepM VF
HCV84_RS26630 () 30617..31066 - 450 WP_001023257.1 copper resistance protein -
HCV84_RS26635 () 31300..33117 + 1818 WP_000925242.1 multicopper oxidase PcoA -
HCV84_RS26640 () 33123..34013 + 891 WP_001378118.1 copper resistance outer membrane transporter PcoB -
HCV84_RS26645 () 34053..34433 + 381 WP_000025662.1 copper resistance system metallochaperone PcoC -
HCV84_RS26650 () 34438..35367 + 930 WP_004118344.1 copper resistance inner membrane protein PcoD -
HCV84_RS26655 () 35422..36102 + 681 WP_001188930.1 Transcriptional activator protein CopR VF
HCV84_RS26660 () 36099..37499 + 1401 WP_004152084.1 copper resistance membrane spanning protein PcoS -
HCV84_RS26665 () 37716..38150 + 435 WP_004152085.1 copper resistance system metallochaperone PcoE -
HCV84_RS26670 () 38382..38561 - 180 WP_024623170.1 type II toxin-antitoxin system RelE/ParE family toxin -
HCV84_RS26675 () 38622..40242 - 1621 Protein_33 ISL3 family transposase -
HCV84_RS26680 () 40304..40813 + 510 WP_004196769.1 aquaporin -
HCV84_RS26685 () 40863..41360 - 498 WP_095348066.1 GNAT family N-acetyltransferase -
HCV84_RS26690 () 41692..42018 + 327 WP_004152092.1 metalloregulator ArsR/SmtB family transcription factor -
HCV84_RS26695 () 42015..42728 + 714 WP_004182006.1 arsenical resistance protein ArsH -
HCV84_RS26700 () 42737..43282 + 546 WP_004182005.1 sigma-70 family RNA polymerase sigma factor -
HCV84_RS26705 () 43358..43720 + 363 WP_004152095.1 arsenic metallochaperone ArsD family protein -
HCV84_RS26710 () 43745..45495 + 1751 Protein_40 arsenical pump-driving ATPase -
HCV84_RS26715 () 45617..46153 + 537 WP_004152096.1 GNAT family N-acetyltransferase -
HCV84_RS26720 () 46186..46611 - 426 WP_004152097.1 glutaredoxin-dependent arsenate reductase -
HCV84_RS26725 () 46624..47913 - 1290 WP_004152098.1 arsenite efflux transporter membrane subunit ArsB -
HCV84_RS26730 () 47961..49712 - 1752 WP_004152099.1 Arsenical pump-driving ATPase VF
HCV84_RS26735 () 49730..50092 - 363 WP_004152100.1 arsenite efflux transporter metallochaperone ArsD -
HCV84_RS26740 () 50142..50492 - 351 WP_004152101.1 As(III)-sensing metalloregulatory transcriptional repressor ArsR -
HCV84_RS26745 () 50850..51119 + 270 WP_004152102.1 hypothetical protein -
HCV84_RS26750 () 51107..51682 + 576 WP_004152103.1 hypothetical protein -
HCV84_RS26755 () 51713..52207 + 495 WP_004152104.1 DNA-binding protein -
HCV84_RS26760 () 52251..52619 + 369 WP_004152105.1 hypothetical protein -
HCV84_RS26765 () 52653..52856 + 204 WP_004152106.1 hemolysin expression modulator Hha -
HCV84_RS26770 () 52905..53162 + 258 WP_004152107.1 hypothetical protein -
HCV84_RS26775 () 53238..53492 + 255 WP_004152108.1 hypothetical protein -
HCV84_RS26780 () 53668..53934 + 267 WP_003026799.1 DUF1778 domain-containing protein Antitoxin Detail
HCV84_RS26785 () 53922..54404 + 483 WP_003026803.1 GNAT family N-acetyltransferase Toxin Detail
HCV84_RS26790 () 54616..55962 + 1347 WP_020314316.1 ISNCY family transposase ISLad2 Transposase
HCV84_RS26795 () 56463..57717 - 1255 Protein_57 IS3 family transposase ISKpn38 Transposase
HCV84_RS26800 () 57805..58767 - 963 WP_004152113.1 M48 family metalloprotease -
HCV84_RS26805 () 58754..59503 - 750 WP_009483782.1 phosphate-starvation-inducible PsiE family protein -
HCV84_RS26810 () 59741..59938 - 198 WP_004152115.1 hypothetical protein -
HCV84_RS26815 () 59938..62733 - 2796 WP_004152116.1 ATP-dependent Clp protease ATP-binding subunit ClpC VF
HCV84_RS26820 () 62848..63417 - 570 WP_004152117.1 Spore protein SP21 VF
HCV84_RS26825 () 63452..63733 - 282 WP_004152118.1 helix-turn-helix domain-containing protein -
HCV84_RS26830 () 63977..64240 - 264 WP_004118208.1 hypothetical protein -
HCV84_RS26835 () 64255..64518 + 264 WP_004118209.1 transposase -
HCV84_RS26840 () 64463..64579 + 117 Protein_66 transposase domain-containing protein -
HCV84_RS26845 () 64764..65461 + 698 Protein_67 IS1 family transposase IS1X3 Transposase
HCV84_RS26850 () 65720..66700 + 981 WP_000019473.1 IS5 family transposase ISKpn26 Transposase
HCV84_RS26855 () 67282..67801 - 520 Protein_69 IS5 family transposase ISPst7 Transposase
HCV84_RS26860 () 67909..68778 - 870 WP_004152692.1 HTH-type transcriptional activator CmpR VF
HCV84_RS26865 () 68772..69782 - 1011 WP_004152693.1 phosphonate dehydrogenase PtxD -
HCV84_RS26870 () 69791..70618 - 828 WP_004152694.1 phosphonate ABC transporter, permease protein PhnE -
HCV84_RS26875 () 70627..71490 - 864 WP_004152695.1 phosphate/phosphite/phosphonate ABC transporter substrate-binding protein -
HCV84_RS26880 () 71487..72314 - 828 WP_004153729.1 Glutamine transport ATP-binding protein GlnQ VF
HCV84_RS26885 () 72656..72964 + 309 Protein_75 IS5 family transposase ISThi1 Transposase
HCV84_RS26890 () 73170..73874 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
HCV84_RS26895 () 74934..76667 - 1734 WP_004118832.1 Glutathione import ATP-binding protein GsiA VF
HCV84_RS26900 () 76675..77622 - 948 WP_004118225.1 acetamidase/formamidase family protein -
HCV84_RS26905 () 77667..79271 - 1605 WP_004152278.1 ABC transporter substrate-binding protein -
HCV84_RS26910 () 79284..80204 - 921 WP_004118227.1 ABC transporter permease -
HCV84_RS26915 () 80204..81052 - 849 WP_004118228.1 ABC transporter permease -
HCV84_RS26920 () 81049..81642 - 594 WP_004118229.1 ANTAR domain-containing protein -
HCV84_RS26925 () 81639..82766 - 1128 WP_004197047.1 transporter substrate-binding protein -
HCV84_RS26930 () 83051..83218 - 168 WP_004118231.1 integrase -
HCV84_RS26935 () 83360..83845 + 486 Protein_85 IS21 family transposase ISEc62 Transposase
HCV84_RS26940 () 84321..84842 + 522 WP_004197062.1 putative RNA polymerase sigma factor FecI VF
HCV84_RS26945 () 84839..85792 + 954 WP_004197067.1 fec operon regulator FecR -
HCV84_RS26950 () 85879..88203 + 2325 WP_004182128.1 Fe(3+) dicitrate transport protein FecA -
HCV84_RS26955 () 88248..89150 + 903 WP_004182127.1 Fe(3+) dicitrate ABC transporter substrate-binding protein FecB -
HCV84_RS26960 () 89147..90145 + 999 WP_004182126.1 Fe(3+) dicitrate transport system permease protein FecC VF
HCV84_RS26965 () 90142..91098 + 957 WP_004118246.1 Fe(3+) dicitrate transport system permease protein FecD VF
HCV84_RS26970 () 91099..91866 + 768 WP_004152282.1 Fe(3+) dicitrate transport ATP-binding protein FecE VF
HCV84_RS26975 () 91965..92258 + 294 WP_004118251.1 IS66 family transposase ISKpn24 Transposase
HCV84_RS26980 () 92333..92560 + 228 Protein_94 IS66 family transposase -
HCV84_RS26985 () 92589..92876 - 288 WP_167589880.1 EAL domain-containing protein -
HCV84_RS26990 () 93210..94220 - 1011 WP_004152284.1 zinc-binding alcohol dehydrogenase family protein -
HCV84_RS26995 () 94681..95763 + 1083 WP_016831235.1 DNA-binding transcriptional repressor LacI -
HCV84_RS27000 () 95885..98959 + 3075 WP_085332116.1 beta-galactosidase -
HCV84_RS27005 () 99011..100264 + 1254 WP_004182120.1 lactose permease -
HCV84_RS27010 () 100330..100470 + 141 Protein_100 galactoside O-acetyltransferase -
HCV84_RS27015 () 100485..101181 - 697 Protein_101 IS1 family transposase -
HCV84_RS27020 () 101370..101630 - 261 WP_004182118.1 DUF2534 family protein -
HCV84_RS27025 () 101687..103750 - 2064 WP_004182117.1 TonB-dependent copper receptor -
HCV84_RS27030 () 103833..104252 - 420 WP_015065566.1 DUF2946 domain-containing protein -
HCV84_RS27035 () 105195..105479 + 285 WP_000537151.1 IS3 family transposase ISEc15 Transposase
HCV84_RS27040 () 105476..106330 + 855 WP_077254108.1 IS3 family transposase ISEc15 Transposase
HCV84_RS27045 () 106716..107036 + 321 WP_004197483.1 hypothetical protein -
HCV84_RS27050 () 107142..108173 - 1032 WP_004176137.1 IS630 family transposase ISEc33 Transposase
HCV84_RS27055 () 109137..109523 + 387 Protein_109 Tn3 family transposase TnpA_TnEc1 Transposase
HCV84_RS27060 () 109547..110569 + 1023 WP_001567660.1 IS110 family transposase ISSm1 Transposase
HCV84_RS27065 () 110990..113566 - 2577 WP_004182109.1 hypothetical protein -
HCV84_RS27070 () 113569..115743 - 2175 WP_004182108.1 AAA family ATPase -
HCV84_RS27075 () 116273..117241 - 969 WP_074169047.1 IS5 family transposase IS903 Transposase
HCV84_RS27080 () 117579..119768 + 2190 WP_004182103.1 anti-phage defense ZorAB system ZorA -
HCV84_RS27085 () 119782..120522 + 741 WP_004182101.1 OmpA family protein -
HCV84_RS27090 () 120519..122201 + 1683 WP_004182099.1 hypothetical protein -
HCV84_RS27095 () 122201..125449 + 3249 WP_004182096.1 DEAD/DEAH box helicase -
HCV84_RS27100 () 125557..126630 - 1074 WP_004118212.1 FUSC family protein -
HCV84_RS27105 () 126896..127393 + 498 WP_032428980.1 DUF2778 domain-containing protein -
HCV84_RS27110 () 127576..128040 - 465 Protein_120 IS21 family transposase ISEc10 Transposase
HCV84_RS27115 () 128095..128487 - 393 Protein_121 IS5 family transposase IS903B Transposase
HCV84_RS27120 () 128751..129083 + 333 WP_001549890.1 metalloregulator ArsR/SmtB family transcription factor -
HCV84_RS27125 () 129089..129802 + 714 WP_025801347.1 arsenical resistance protein ArsH -
HCV84_RS27130 () 129860..130288 - 429 WP_001549888.1 glutaredoxin-dependent arsenate reductase -
HCV84_RS27135 () 130338..131621 - 1284 WP_001549887.1 arsenic transporter -
HCV84_RS27140 () 131717..132070 - 354 WP_001549886.1 metalloregulator ArsR/SmtB family transcription factor -
HCV84_RS27145 () 132554..134032 + 1479 WP_001549885.1 SulP family inorganic anion transporter -
HCV84_RS27150 () 134051..134878 + 828 WP_004118529.1 universal stress protein -
HCV84_RS27155 () 134950..136146 - 1197 WP_001549953.1 MFS transporter -
HCV84_RS27160 () 136675..137049 + 375 WP_004118534.1 fluoride efflux transporter CrcB -
HCV84_RS27165 () 137324..138472 + 1149 WP_011977829.1 Na+/H+ antiporter NhaA -
HCV84_RS27170 () 138826..139158 - 333 WP_004118538.1 multidrug efflux SMR transporter -
HCV84_RS27175 () 139290..139847 - 558 WP_004118540.1 Tn3 family transposase ISEc63 Transposase
HCV84_RS27180 () 140009..141076 + 1068 Protein_134 Tn3 family transposase TnpA_Tn3 Transposase
HCV84_RS27185 () 141112..141669 - 558 WP_003100847.1 Tn3 family transposase TnpR_ISPa38 Transposase
HCV84_RS27190 () 141663..142034 - 372 WP_003100853.1 hypothetical protein -
HCV84_RS27195 () 142031..142531 - 501 WP_003100856.1 hypothetical protein -
HCV84_RS27200 () 142528..142854 - 327 WP_003100858.1 hypothetical protein -
HCV84_RS27205 () 143109..143465 - 357 WP_000215515.1 cupin domain-containing protein -
HCV84_RS27210 () 143455..143856 - 402 WP_001293886.1 DUF86 domain-containing protein -
HCV84_RS27215 () 143853..144143 - 291 WP_001247892.1 nucleotidyltransferase -
HCV84_RS27220 () 144450..144572 - 123 Protein_142 integrase -
HCV84_RS27225 () 144599..147484 - 2886 WP_032428972.1 Tn3 family transposase TnpA_ISRsp12 Transposase
HCV84_RS27230 () 147610..148224 + 615 WP_000904906.1 Tn3 family transposase TnpR_ISMex22 Transposase
HCV84_RS27235 () 148290..149093 + 804 WP_001082319.1 Aminoglycoside 3'-phosphotransferase ARG
HCV84_RS27240 () 149093..149929 + 837 WP_000480968.1 hypothetical protein ARG
HCV84_RS27245 () 149901..150938 - 1038 WP_057174284.1 IS91 family transposase ISAzo26 Transposase
HCV84_RS27250 () 151040..151891 + 852 WP_000946487.1 Dihydropteroate synthase ARG
HCV84_RS27255 () 152019..152519 + 501 WP_000376623.1 GNAT family N-acetyltransferase -
HCV84_RS27260 () 152840..152908 + 69 Protein_150 EAL domain-containing protein -
HCV84_RS27265 () 153026..153544 + 519 Protein_151 IS6 family transposase IS6100 Transposase
HCV84_RS27270 () 153607..154311 + 705 WP_001067856.1 IS6 family transposase IS15DII Transposase
HCV84_RS27275 () 154387..154872 + 486 WP_004178063.1 hypothetical protein VF
HCV84_RS27280 () 154905..155234 - 330 WP_011977736.1 hypothetical protein -
HCV84_RS27285 () 155267..156088 - 822 WP_004182076.1 DUF945 domain-containing protein -
HCV84_RS27290 () 156921..157334 - 414 WP_004182074.1 helix-turn-helix domain-containing protein -
HCV84_RS27295 () 157335..157613 - 279 WP_004152721.1 helix-turn-helix domain-containing protein -
HCV84_RS27300 () 157603..157923 - 321 WP_004152720.1 type II toxin-antitoxin system RelE/ParE family toxin -
HCV84_RS27305 () 158004..158228 - 225 WP_004152719.1 hypothetical protein -
HCV84_RS27310 () 158239..158451 - 213 WP_004182070.1 hypothetical protein -
HCV84_RS27315 () 158512..158868 - 357 WP_004152717.1 hypothetical protein -
HCV84_RS27320 () 159504..159854 - 351 WP_004182068.1 hypothetical protein -
HCV84_RS27325 () 159851..160123 - 273 WP_004182067.1 hypothetical protein -
HCV84_RS27330 () 160819..160980 - 162 WP_004118124.1 type I toxin-antitoxin system Hok family toxin -
HCV84_RS27335 () 161208..161582 - 375 WP_004182064.1 hypothetical protein -
HCV84_RS27340 () 161638..161964 - 327 WP_004152639.1 hypothetical protein -
HCV84_RS27345 () 161961..162689 - 729 WP_004152640.1 plasmid SOS inhibition protein A -
HCV84_RS27350 () 162686..163117 - 432 WP_004182061.1 conjugation system SOS inhibitor PsiB -
HCV84_RS27355 () 163162..165219 - 2058 WP_004182059.1 ParB/RepB/Spo0J family partition protein -
HCV84_RS27360 () 165289..165537 - 249 WP_004182058.1 DUF905 domain-containing protein -
HCV84_RS27365 () 165586..166128 - 543 WP_004182056.1 single-stranded DNA-binding protein -
HCV84_RS27370 () 166924..167241 - 318 WP_004118473.1 hypothetical protein -
HCV84_RS27375 () 167276..167530 - 255 WP_004152754.1 DNA polymerase III subunit theta -
HCV84_RS27380 () 167767..168192 - 426 WP_004118478.1 antirestriction protein -
HCV84_RS27385 () 168712..168942 - 231 WP_004118481.1 hypothetical protein -
HCV84_RS27390 () 169176..170687 - 1512 WP_024623221.1 Group II intron-encoded protein LtrA VF
HCV84_RS27395 () 171089..171514 + 426 WP_004182047.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
HCV84_RS27400 () 171514..172786 + 1273 Protein_178 Y-family DNA polymerase -
HCV84_RS27405 () 172865..173116 + 252 WP_004182043.1 hypothetical protein -
HCV84_RS27410 () 173361..175313 - 1953 WP_000037308.1 DUF262 domain-containing HNH endonuclease family protein -
HCV84_RS27415 () 175310..176590 - 1281 WP_004182042.1 DUF262 domain-containing protein -
HCV84_RS27420 () 177558..178253 + 696 Protein_182 IS1 family transposase -
HCV84_RS27425 () 179031..180147 - 1117 Protein_183 IS3 family transposase ISSen4 Transposase
HCV84_RS27430 () 181018..181989 - 972 WP_004182039.1 ParB/RepB/Spo0J family plasmid partition protein -
HCV84_RS27435 () 181989..183155 - 1167 WP_004182032.1 Sporulation initiation inhibitor protein Soj VF

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance