MGE detailed information
MGE type: Mobilizable plasmid MGE length: 123177 bp
Accession: NZ_CP054740 Location: 1..123177 Organism: Klebsiella pneumoniae strain KP20194c5 Replicon: plasmid pKP20194c5-p2
Accession: NZ_CP054740 Location: 1..123177 Organism: Klebsiella pneumoniae strain KP20194c5 Replicon: plasmid pKP20194c5-p2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HUS05_RS27945 () | 1797..2450 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| HUS05_RS27950 () | 2543..2800 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| HUS05_RS27955 () | 2733..3134 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| HUS05_RS27960 () | 3383..3798 | + | 416 | Protein_4 | IS1 family transposase | - |
| HUS05_RS27965 () | 3834..4379 | - | 546 | Protein_5 | Tn3 family transposase TnpA_Tn3 | Transposase |
| HUS05_RS27970 () | 4445..5149 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HUS05_RS27975 () | 5219..5410 | + | 192 | Protein_7 | transposase | - |
| HUS05_RS27980 () | 5660..6535 | + | 876 | WP_013188475.1 | Beta-lactamase Toho-1 | ARG |
| HUS05_RS27985 () | 6570..7538 | + | 969 | WP_013362812.1 | IS5 family transposase IS903B | Transposase |
| HUS05_RS27990 () | 7771..8052 | + | 282 | WP_001333089.1 | hypothetical protein | - |
| HUS05_RS27995 () | 8175..8525 | - | 351 | WP_000361389.1 | plasmid partitioning/stability family protein | - |
| HUS05_RS28000 () | 8528..9490 | - | 963 | WP_000959884.1 | plasmid segregation protein ParM | - |
| HUS05_RS28005 () | 9637..9930 | + | 294 | WP_032146011.1 | hypothetical protein | - |
| HUS05_RS28010 () | 10007..10690 | + | 684 | WP_000085883.1 | DNA methylase | - |
| HUS05_RS28015 () | 10691..10912 | + | 222 | WP_001104881.1 | hypothetical protein | - |
| HUS05_RS28020 () | 10926..11360 | + | 435 | WP_000274503.1 | DUF1380 family protein | - |
| HUS05_RS28025 () | 11411..12187 | + | 777 | WP_001383963.1 | hypothetical protein | - |
| HUS05_RS28030 () | 12605..13030 | + | 426 | WP_001198928.1 | antirestriction protein | - |
| HUS05_RS28035 () | 13077..13499 | + | 423 | WP_000271762.1 | DUF1380 family protein | - |
| HUS05_RS28040 () | 13496..13687 | + | 192 | WP_001027493.1 | hypothetical protein | - |
| HUS05_RS28045 () | 14001..15668 | - | 1668 | WP_012372796.1 | group II intron reverse transcriptase/maturase | - |
| HUS05_RS28050 () | 17068..17298 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| HUS05_RS28055 () | 17350..18711 | + | 1362 | WP_000170695.1 | DUF3560 domain-containing protein | - |
| HUS05_RS28060 () | 18758..19321 | + | 564 | WP_015059007.1 | class I SAM-dependent methyltransferase | - |
| HUS05_RS28065 () | 19407..19862 | - | 456 | Protein_25 | hypothetical protein | - |
| HUS05_RS28070 () | 20164..20691 | + | 528 | WP_000290834.1 | single-stranded DNA-binding protein | - |
| HUS05_RS28075 () | 20749..20982 | + | 234 | WP_000006003.1 | DUF905 family protein | - |
| HUS05_RS28080 () | 21043..23066 | + | 2024 | Protein_28 | ParB/RepB/Spo0J family partition protein | - |
| HUS05_RS28085 () | 23135..23569 | + | 435 | WP_000845953.1 | conjugation system SOS inhibitor PsiB | - |
| HUS05_RS28090 () | 23566..24285 | + | 720 | WP_001276217.1 | plasmid SOS inhibition protein A | - |
| - () | 24297..24521 | + | 225 | NuclAT_0 | - | - |
| - () | 24297..24521 | + | 225 | NuclAT_0 | - | - |
| - () | 24297..24521 | + | 225 | NuclAT_0 | - | - |
| - () | 24297..24521 | + | 225 | NuclAT_0 | - | - |
| HUS05_RS28095 () | 24565..24723 | + | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| HUS05_RS28100 () | 24961..25338 | - | 378 | Protein_32 | hypothetical protein | - |
| HUS05_RS28105 () | 25638..25934 | + | 297 | WP_001272251.1 | hypothetical protein | - |
| HUS05_RS28110 () | 26045..26866 | + | 822 | WP_001234445.1 | DUF945 domain-containing protein | - |
| HUS05_RS28115 () | 27163..27810 | - | 648 | WP_015059008.1 | hypothetical protein | VF |
| HUS05_RS28120 () | 28087..28470 | + | 384 | WP_000124981.1 | relaxosome protein TraM | - |
| HUS05_RS28125 () | 28751..29455 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HUS05_RS28130 () | 29509..29832 | - | 324 | Protein_38 | class II aldolase/adducin family protein | - |
| HUS05_RS28135 () | 29825..31077 | - | 1253 | Protein_39 | four-carbon acid sugar kinase family protein | - |
| HUS05_RS28140 () | 31089..31991 | - | 903 | WP_002903955.1 | NAD(P)-dependent oxidoreductase | - |
| HUS05_RS28145 () | 32253..33014 | + | 762 | WP_002210513.1 | DeoR/GlpR family DNA-binding transcription regulator | - |
| HUS05_RS28150 () | 33035..33895 | - | 861 | WP_002904004.1 | Beta-lactamase SHV-2 | ARG |
| HUS05_RS28155 () | 34032..34100 | + | 69 | Protein_43 | IS6 family transposase | - |
| HUS05_RS28160 () | 34136..37102 | - | 2967 | WP_001138014.1 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| HUS05_RS28165 () | 37106..37666 | - | 561 | WP_001161490.1 | Tn3 family transposase TnpR_TnAs1 | Transposase |
| HUS05_RS28170 () | 38058..38675 | + | 618 | Protein_46 | replication protein | - |
| HUS05_RS28175 () | 39209..39487 | + | 279 | WP_013213990.1 | hypothetical protein | - |
| HUS05_RS28180 () | 39598..40023 | + | 426 | WP_013213989.1 | antirestriction protein | - |
| HUS05_RS28185 () | 40151..40306 | + | 156 | WP_013213988.1 | hypothetical protein | - |
| HUS05_RS28190 () | 40352..40648 | + | 297 | WP_013213987.1 | transcriptional regulator | - |
| HUS05_RS28195 () | 40653..40778 | + | 126 | Protein_51 | IS1182 family transposase ISKpn6 | Transposase |
| HUS05_RS28200 () | 40752..41633 | + | 882 | Protein_52 | IS1182 family transposase ISKpn6 | Transposase |
| HUS05_RS28205 () | 41883..42764 | - | 882 | WP_004199234.1 | Carbapenem-hydrolyzing beta-lactamase KPC | ARG |
| HUS05_RS28210 () | 43040..44020 | - | 981 | WP_013213985.1 | IS481 family transposase ISKpn27 | Transposase |
| HUS05_RS28215 () | 44143..44616 | - | 474 | WP_014343468.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| HUS05_RS28220 () | 44656..45360 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HUS05_RS28225 () | 45425..46597 | - | 1173 | Protein_57 | transposase | - |
| HUS05_RS28230 () | 46672..47340 | - | 669 | WP_001300294.1 | putative signaling protein | VF |
| HUS05_RS28235 () | 47376..47612 | - | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| HUS05_RS28240 () | 47609..47971 | - | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| HUS05_RS28245 () | 47989..49683 | - | 1695 | WP_000105636.1 | mercury(II) reductase | - |
| HUS05_RS28250 () | 49735..50157 | - | 423 | WP_001340589.1 | organomercurial transporter MerC | - |
| HUS05_RS28255 () | 50193..50468 | - | 276 | WP_000732292.1 | mercury resistance system periplasmic binding protein MerP | - |
| HUS05_RS28260 () | 50482..50832 | - | 351 | WP_001294663.1 | mercuric transport protein MerT | - |
| HUS05_RS28265 () | 50904..51338 | + | 435 | WP_000429836.1 | IS607 family transposase ISChh1 | Transposase |
| HUS05_RS28270 () | 51417..52421 | + | 1005 | WP_000427619.1 | IS110 family transposase IS5075 | Transposase |
| HUS05_RS28275 () | 52949..54349 | - | 1401 | WP_004152084.1 | copper resistance membrane spanning protein PcoS | - |
| HUS05_RS28280 () | 54346..55026 | - | 681 | WP_001188930.1 | Transcriptional activator protein CopR | VF |
| HUS05_RS28285 () | 55081..56010 | - | 930 | WP_004213583.1 | copper resistance inner membrane protein PcoD | - |
| HUS05_RS28290 () | 56015..56395 | - | 381 | WP_000025662.1 | copper resistance system metallochaperone PcoC | - |
| HUS05_RS28295 () | 56435..57325 | - | 891 | WP_029884201.1 | copper resistance outer membrane transporter PcoB | - |
| HUS05_RS28300 () | 57331..59148 | - | 1818 | WP_004213580.1 | multicopper oxidase PcoA | - |
| HUS05_RS28305 () | 59382..59849 | + | 468 | WP_048336866.1 | hypothetical protein | - |
| HUS05_RS28310 () | 60116..60853 | + | 738 | WP_004118669.1 | Murein DD-endopeptidase MepM | VF |
| HUS05_RS28315 () | 60887..61084 | - | 198 | WP_000843497.1 | DUF2933 domain-containing protein | - |
| HUS05_RS28320 () | 61125..63572 | - | 2448 | WP_004098955.1 | Ag(+)-translocating P-type ATPase SilP | - |
| HUS05_RS28325 () | 63699..64139 | - | 441 | WP_000758228.1 | hypothetical protein | - |
| HUS05_RS28330 () | 64226..67372 | - | 3147 | WP_004098958.1 | Cu(+)/Ag(+) efflux RND transporter permease subunit SilA | - |
| HUS05_RS28335 () | 67383..68675 | - | 1293 | WP_004213579.1 | Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB | - |
| HUS05_RS28340 () | 68789..69151 | - | 363 | WP_004213578.1 | cation efflux system protein CusF | - |
| HUS05_RS28345 () | 69180..70565 | - | 1386 | WP_004213577.1 | Cation efflux system protein CusC | VF |
| HUS05_RS28350 () | 70755..71435 | + | 681 | WP_004213574.1 | Transcriptional regulatory protein CusR | VF |
| HUS05_RS28355 () | 71428..72903 | + | 1476 | WP_000555737.1 | copper/silver sensor histidine kinase SilS | - |
| HUS05_RS28360 () | 73154..73585 | + | 432 | WP_023302802.1 | silver-binding protein SilE | - |
| HUS05_RS28365 () | 73729..74079 | + | 351 | WP_004213569.1 | DUF305 domain-containing protein | - |
| HUS05_RS28370 () | 74466..75374 | - | 909 | WP_023302803.1 | HNH endonuclease | - |
| HUS05_RS28375 () | 76011..76985 | + | 975 | WP_004213565.1 | sensor domain-containing diguanylate cyclase | - |
| HUS05_RS28380 () | 77570..78514 | + | 945 | WP_011977810.1 | hypothetical protein | - |
| HUS05_RS28385 () | 78551..78943 | + | 393 | WP_011977811.1 | hypothetical protein | - |
| HUS05_RS28390 () | 79001..79522 | + | 522 | WP_013214008.1 | hypothetical protein | - |
| HUS05_RS28395 () | 79568..79771 | + | 204 | WP_011977813.1 | hypothetical protein | - |
| HUS05_RS28400 () | 79801..80805 | + | 1005 | WP_011977814.1 | hypothetical protein | - |
| HUS05_RS28405 () | 80989..81768 | + | 780 | WP_013214009.1 | site-specific integrase | - |
| HUS05_RS28410 () | 81814..82071 | - | 258 | WP_013214010.1 | hypothetical protein | - |
| HUS05_RS28415 () | 82200..82313 | - | 114 | WP_014343462.1 | hypothetical protein | - |
| HUS05_RS28420 () | 82849..83715 | + | 867 | WP_004118283.1 | replication initiation protein | - |
| HUS05_RS28425 () | 84825..86030 | + | 1206 | WP_011977818.1 | AAA family ATPase | - |
| HUS05_RS28430 () | 86030..87004 | + | 975 | WP_011977819.1 | ParB/RepB/Spo0J family partition protein | - |
| HUS05_RS28435 () | 87086..88357 | - | 1272 | WP_013214011.1 | Y-family DNA polymerase | - |
| HUS05_RS28440 () | 88357..88788 | - | 432 | WP_001568036.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| HUS05_RS28445 () | 89195..90682 | + | 1488 | WP_004178082.1 | group II intron reverse transcriptase/maturase | - |
| HUS05_RS28450 () | 90931..91902 | + | 972 | WP_004152353.1 | mediator of plasmid stability | - |
| HUS05_RS28455 () | 91905..92576 | + | 672 | WP_013214012.1 | plasmid partitioning/stability family protein | - |
| HUS05_RS28460 () | 92639..92869 | + | 231 | WP_001568040.1 | hypothetical protein | - |
| HUS05_RS28465 () | 93306..94007 | + | 702 | WP_001568041.1 | DNA methylase | - |
| HUS05_RS28470 () | 94007..94228 | + | 222 | WP_001568042.1 | hypothetical protein | - |
| HUS05_RS28475 () | 94238..94657 | + | 420 | WP_001568043.1 | DUF1380 domain-containing protein | - |
| HUS05_RS28480 () | 94711..95478 | + | 768 | WP_013214013.1 | hypothetical protein | - |
| HUS05_RS28485 () | 96159..96587 | + | 429 | WP_001568045.1 | antirestriction protein | - |
| HUS05_RS28490 () | 96630..97136 | + | 507 | WP_013214014.1 | antirestriction protein ArdA | - |
| HUS05_RS28495 () | 97179..97370 | + | 192 | WP_001568047.1 | hypothetical protein | - |
| HUS05_RS28500 () | 97558..97812 | + | 255 | WP_011977779.1 | DNA polymerase III subunit theta | - |
| HUS05_RS28505 () | 97847..98167 | + | 321 | WP_001568049.1 | hypothetical protein | - |
| HUS05_RS28510 () | 98847..99074 | + | 228 | WP_001568050.1 | hypothetical protein | - |
| HUS05_RS28515 () | 99166..99396 | + | 231 | WP_001568051.1 | hypothetical protein | - |
| HUS05_RS28520 () | 99448..100803 | + | 1356 | WP_014343515.1 | DUF3560 domain-containing protein | - |
| HUS05_RS28525 () | 100851..101414 | + | 564 | WP_014343514.1 | methyltransferase | - |
| HUS05_RS28530 () | 102247..102789 | + | 543 | WP_014343512.1 | single-stranded DNA-binding protein | - |
| HUS05_RS28535 () | 102838..103086 | + | 249 | WP_001568055.1 | DUF905 domain-containing protein | - |
| HUS05_RS28540 () | 103156..105213 | + | 2058 | WP_015493064.1 | ParB/RepB/Spo0J family partition protein | - |
| HUS05_RS28545 () | 105258..105689 | + | 432 | WP_001568057.1 | conjugation system SOS inhibitor PsiB | - |
| HUS05_RS28550 () | 105686..106414 | + | 729 | WP_001568058.1 | plasmid SOS inhibition protein A | - |
| HUS05_RS28555 () | 106411..106737 | + | 327 | WP_013023807.1 | hypothetical protein | - |
| HUS05_RS28560 () | 106793..107167 | + | 375 | WP_014343510.1 | hypothetical protein | - |
| HUS05_RS28565 () | 107395..107553 | + | 159 | WP_014343509.1 | type I toxin-antitoxin system Hok family toxin | - |
| HUS05_RS28570 () | 108246..108518 | + | 273 | WP_040245921.1 | hypothetical protein | - |
| HUS05_RS28575 () | 108515..108865 | + | 351 | WP_040245917.1 | hypothetical protein | - |
| HUS05_RS28580 () | 108880..109197 | + | 318 | WP_014343505.1 | hypothetical protein | - |
| HUS05_RS28585 () | 110038..110394 | + | 357 | WP_014343501.1 | hypothetical protein | - |
| HUS05_RS28590 () | 110455..110667 | + | 213 | WP_014343500.1 | hypothetical protein | - |
| HUS05_RS28595 () | 110678..110902 | + | 225 | WP_014343499.1 | hypothetical protein | - |
| HUS05_RS28600 () | 110983..111303 | + | 321 | WP_014343498.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| HUS05_RS28605 () | 111293..111571 | + | 279 | WP_004152721.1 | helix-turn-helix domain-containing protein | - |
| HUS05_RS28610 () | 112508..113329 | + | 822 | WP_004152492.1 | DUF945 domain-containing protein | - |
| HUS05_RS28615 () | 113362..113691 | + | 330 | WP_013214015.1 | hypothetical protein | - |
| HUS05_RS28620 () | 113724..114209 | - | 486 | WP_014343495.1 | hypothetical protein | VF |
| HUS05_RS28625 () | 114600..115016 | + | 417 | WP_014343494.1 | relaxosome protein TraM | - |
| HUS05_RS28630 () | 115216..115953 | + | 738 | WP_154244330.1 | conjugal transfer protein TrbJ | - |
| HUS05_RS28635 () | 116068..116274 | + | 207 | WP_171773970.1 | TraY domain-containing protein | - |
| HUS05_RS28640 () | 116336..116704 | + | 369 | WP_004194426.1 | type IV conjugative transfer system pilin TraA | - |
| HUS05_RS28645 () | 116718..117023 | + | 306 | WP_004144424.1 | type IV conjugative transfer system protein TraL | - |
| HUS05_RS28650 () | 117043..117408 | + | 366 | Protein_142 | type IV conjugative transfer system protein TraE | - |
| HUS05_RS28655 () | 117463..117807 | - | 345 | Protein_143 | IS6 family transposase IS26 | Transposase |
| HUS05_RS28660 () | 117859..118563 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HUS05_RS28665 () | 118627..118788 | + | 162 | Protein_145 | DNA helicase | - |
| HUS05_RS28670 () | 118808..119554 | + | 747 | WP_000205770.1 | conjugal transfer pilus acetylase TraX | - |
| HUS05_RS28675 () | 119609..120169 | + | 561 | WP_000139328.1 | fertility inhibition protein FinO | - |
| HUS05_RS28680 () | 120301..120501 | + | 201 | WP_015059022.1 | hypothetical protein | - |
| HUS05_RS28685 () | 120887..121486 | + | 600 | WP_032083981.1 | hypothetical protein | - |
| HUS05_RS28690 () | 121650..121880 | + | 231 | WP_001736714.1 | hypothetical protein | - |
| - () | 122081..122140 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| - () | 122081..122140 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| - () | 122081..122140 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| - () | 122081..122140 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| HUS05_RS28695 () | 122185..122334 | + | 150 | WP_001312851.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| HUS05_RS28700 () | 122618..122866 | + | 249 | WP_000083837.1 | replication regulatory protein RepA | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|