MGE detailed information
MGE type: Non-Mobilizable plasmid MGE length: 168717 bp
Accession: NZ_CP054265 Location: 1..168717 Organism: Klebsiella pneumoniae strain 39427 Replicon: plasmid pKPN39427.1
Accession: NZ_CP054265 Location: 1..168717 Organism: Klebsiella pneumoniae strain 39427 Replicon: plasmid pKPN39427.1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HPS02_RS00005 () | 175..405 | + | 231 | WP_004152753.1 | hypothetical protein | - |
| HPS02_RS00010 () | 926..1351 | + | 426 | WP_004118478.1 | antirestriction protein | - |
| HPS02_RS00015 () | 1588..1842 | + | 255 | WP_004152754.1 | DNA polymerase III subunit theta | - |
| HPS02_RS00020 () | 1877..2194 | + | 318 | WP_004118473.1 | hypothetical protein | - |
| HPS02_RS00025 () | 2934..3476 | + | 543 | WP_004152644.1 | single-stranded DNA-binding protein | - |
| HPS02_RS00030 () | 3525..3773 | + | 249 | WP_004152643.1 | DUF905 domain-containing protein | - |
| HPS02_RS00035 () | 3843..5879 | + | 2037 | WP_004178066.1 | ParB/RepB/Spo0J family partition protein | - |
| HPS02_RS00040 () | 5946..6377 | + | 432 | WP_004152641.1 | conjugation system SOS inhibitor PsiB | - |
| HPS02_RS00045 () | 6374..7102 | + | 729 | WP_004152640.1 | plasmid SOS inhibition protein A | - |
| HPS02_RS00050 () | 7099..7425 | + | 327 | WP_004152639.1 | hypothetical protein | - |
| HPS02_RS00055 () | 7481..7855 | + | 375 | WP_004152638.1 | hypothetical protein | - |
| HPS02_RS00060 () | 8033..9112 | - | 1080 | WP_004220208.1 | IS481 family transposase ISKpn28 | Transposase |
| HPS02_RS00065 () | 9184..9345 | + | 162 | WP_004118124.1 | type I toxin-antitoxin system Hok family toxin | - |
| HPS02_RS00070 () | 10045..10317 | + | 273 | WP_004152759.1 | hypothetical protein | - |
| HPS02_RS00075 () | 10314..10664 | + | 351 | WP_004152758.1 | hypothetical protein | - |
| HPS02_RS00080 () | 11300..11656 | + | 357 | WP_004152717.1 | hypothetical protein | - |
| HPS02_RS00085 () | 11717..11929 | + | 213 | WP_004152718.1 | hypothetical protein | - |
| HPS02_RS00090 () | 11940..12164 | + | 225 | WP_004152719.1 | hypothetical protein | - |
| HPS02_RS00095 () | 12245..12565 | + | 321 | WP_004152720.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| HPS02_RS00100 () | 12555..12833 | + | 279 | WP_004152721.1 | helix-turn-helix domain-containing protein | - |
| HPS02_RS00105 () | 12834..13247 | + | 414 | WP_004152722.1 | helix-turn-helix domain-containing protein | - |
| HPS02_RS00110 () | 14081..14902 | + | 822 | WP_004178064.1 | DUF945 domain-containing protein | - |
| HPS02_RS00115 () | 14935..15264 | + | 330 | WP_011977736.1 | hypothetical protein | - |
| HPS02_RS00120 () | 15297..15782 | - | 486 | WP_004178063.1 | hypothetical protein | VF |
| HPS02_RS00125 () | 16216..16608 | + | 393 | WP_004178062.1 | relaxosome protein TraM | - |
| HPS02_RS00130 () | 16831..17517 | + | 687 | WP_011977735.1 | transcriptional regulator TraJ family protein | - |
| HPS02_RS00135 () | 17601..17972 | + | 372 | WP_004208838.1 | TraY domain-containing protein | - |
| HPS02_RS00140 () | 18189..19169 | - | 981 | WP_000019473.1 | IS5 family transposase ISKpn26 | Transposase |
| HPS02_RS00145 () | 19721..20418 | - | 698 | Protein_28 | IS1 family transposase ISKpn14 | Transposase |
| HPS02_RS00150 () | 20475..20816 | + | 342 | Protein_29 | HNH endonuclease | - |
| HPS02_RS00155 () | 20818..21096 | + | 279 | WP_004152296.1 | bacteriocin immunity protein | - |
| HPS02_RS00160 () | 21437..21916 | + | 480 | WP_009485932.1 | Phospholipase D | VF |
| HPS02_RS00165 () | 22237..22515 | + | 279 | WP_004199332.1 | replication regulatory protein RepA | - |
| HPS02_RS00170 () | 22732..22809 | + | 78 | WP_004171457.1 | RepA leader peptide Tap | - |
| HPS02_RS00175 () | 22802..23659 | + | 858 | WP_004152292.1 | incFII family plasmid replication initiator RepA | - |
| HPS02_RS00180 () | 25106..27301 | - | 2196 | WP_000093087.1 | DEAD/DEAH box helicase | - |
| HPS02_RS00185 () | 27298..28614 | - | 1317 | WP_004152291.1 | ATP-binding protein | - |
| HPS02_RS00190 () | 28618..30927 | - | 2310 | WP_004152290.1 | TerB N-terminal domain-containing protein | - |
| HPS02_RS00195 () | 31572..32540 | - | 969 | WP_077264219.1 | IS5 family transposase IS903B | Transposase |
| HPS02_RS00200 () | 32632..33885 | - | 1254 | WP_003846917.1 | lactose permease | - |
| HPS02_RS00205 () | 33937..37011 | - | 3075 | WP_004152287.1 | beta-galactosidase | - |
| HPS02_RS00210 () | 37133..38215 | - | 1083 | WP_004152286.1 | DNA-binding transcriptional repressor LacI | - |
| HPS02_RS00215 () | 38676..39686 | + | 1011 | WP_004152284.1 | zinc-binding alcohol dehydrogenase family protein | - |
| HPS02_RS00220 () | 40020..40307 | + | 288 | WP_165765869.1 | EAL domain-containing protein | - |
| HPS02_RS00225 () | 40336..40563 | - | 228 | Protein_44 | IS66 family transposase | - |
| HPS02_RS00230 () | 40638..40931 | - | 294 | WP_004118251.1 | IS66 family transposase ISKpn24 | Transposase |
| HPS02_RS00235 () | 41030..41797 | - | 768 | WP_004152282.1 | Fe(3+) dicitrate transport ATP-binding protein FecE | VF |
| HPS02_RS00240 () | 41798..42754 | - | 957 | WP_004152281.1 | Fe(3+) dicitrate transport system permease protein FecD | VF |
| HPS02_RS00245 () | 42751..43749 | - | 999 | WP_004118243.1 | Fe(3+) dicitrate transport system permease protein FecC | VF |
| HPS02_RS00250 () | 43746..44648 | - | 903 | WP_004118241.1 | Fe(3+) dicitrate ABC transporter substrate-binding protein FecB | - |
| HPS02_RS00255 () | 44693..47017 | - | 2325 | WP_004152280.1 | Fe(3+) dicitrate transport protein FecA | - |
| HPS02_RS00260 () | 47103..48056 | - | 954 | WP_004118237.1 | fec operon regulator FecR | - |
| HPS02_RS00265 () | 48053..48574 | - | 522 | WP_004118235.1 | putative RNA polymerase sigma factor FecI | VF |
| HPS02_RS00270 () | 49050..49535 | - | 486 | Protein_53 | IS21 family transposase ISEc62 | Transposase |
| HPS02_RS00275 () | 49536..49748 | - | 213 | WP_161989521.1 | hypothetical protein | - |
| HPS02_RS00280 () | 49677..49844 | + | 168 | WP_004118231.1 | integrase | - |
| HPS02_RS00285 () | 50129..51256 | + | 1128 | WP_004118840.1 | transporter substrate-binding protein | - |
| HPS02_RS00290 () | 51253..51846 | + | 594 | WP_004118229.1 | ANTAR domain-containing protein | - |
| HPS02_RS00295 () | 51843..52691 | + | 849 | WP_004152279.1 | ABC transporter permease | - |
| HPS02_RS00300 () | 52691..53611 | + | 921 | WP_004118227.1 | ABC transporter permease | - |
| HPS02_RS00305 () | 53624..55228 | + | 1605 | WP_004152278.1 | ABC transporter substrate-binding protein | - |
| HPS02_RS00310 () | 55273..56220 | + | 948 | WP_004118225.1 | acetamidase/formamidase family protein | - |
| HPS02_RS00315 () | 56228..57961 | + | 1734 | WP_004118832.1 | Glutathione import ATP-binding protein GsiA | VF |
| HPS02_RS00320 () | 59782..60159 | - | 378 | Protein_63 | IS66 family transposase ISEc22 | Transposase |
| HPS02_RS00325 () | 60197..61734 | - | 1538 | Protein_64 | IS66 family transposase ISCfr14 | Transposase |
| HPS02_RS00330 () | 61784..62131 | - | 348 | WP_004152557.1 | IS66 family transposase ISCfr14 | Transposase |
| HPS02_RS00335 () | 62128..62514 | - | 387 | WP_020956879.1 | IS66 family transposase ISSgsp1 | Transposase |
| HPS02_RS00340 () | 63062..63697 | - | 636 | WP_004118217.1 | His-Xaa-Ser repeat protein HxsA | - |
| HPS02_RS00345 () | 63694..64806 | - | 1113 | WP_000005560.1 | His-Xaa-Ser system radical SAM maturase HxsC | - |
| HPS02_RS00350 () | 64799..66187 | - | 1389 | WP_004152560.1 | His-Xaa-Ser system radical SAM maturase HxsB | - |
| HPS02_RS00355 () | 66187..66426 | - | 240 | WP_176716597.1 | His-Xaa-Ser system protein HxsD | - |
| HPS02_RS00360 () | 66419..67116 | - | 698 | Protein_71 | IS1 family transposase IS1R | Transposase |
| HPS02_RS00365 () | 67395..68054 | + | 660 | WP_000412211.1 | Chloramphenicol acetyltransferase | ARG |
| HPS02_RS00370 () | 68255..68632 | - | 378 | WP_000656305.1 | GNAT family N-acetyltransferase | - |
| HPS02_RS00375 () | 68699..71665 | - | 2967 | WP_001138064.1 | Tn3 family transposase TnpA_TnAs3 | Transposase |
| HPS02_RS00380 () | 71668..72228 | - | 561 | WP_000147567.1 | Tn3 family transposase TnpR_TnAs3 | Transposase |
| HPS02_RS00385 () | 72354..72704 | - | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| HPS02_RS00390 () | 72907..73920 | - | 1014 | WP_000845039.1 | IS91 family transposase ISAzo26 | Transposase |
| HPS02_RS00395 () | 74065..74562 | + | 498 | WP_001083725.1 | Dihydrofolate reductase | ARG |
| HPS02_RS00400 () | 74674..74964 | + | 291 | WP_001336345.1 | DUF1010 domain-containing protein | - |
| HPS02_RS00405 () | 74970..75761 | + | 792 | WP_001206356.1 | Streptomycin 3''-adenylyltransferase | ARG |
| HPS02_RS00410 () | 75925..76272 | + | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| HPS02_RS00415 () | 76266..77105 | + | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| HPS02_RS00420 () | 77233..77436 | + | 204 | WP_000376616.1 | hypothetical protein | - |
| HPS02_RS00425 () | 77592..78797 | + | 1206 | WP_000184001.1 | chromate efflux transporter | - |
| HPS02_RS00430 () | 78808..79113 | + | 306 | WP_000130000.1 | hypothetical protein | Relaxase |
| HPS02_RS00435 () | 79157..79222 | + | 66 | Protein_86 | EAL domain-containing protein | - |
| HPS02_RS00440 () | 79340..80104 | + | 765 | WP_001389365.1 | IS6 family transposase IS6100 | Transposase |
| HPS02_RS00445 () | 80597..81181 | - | 585 | WP_001137892.1 | TetR family transcriptional regulator | - |
| HPS02_RS00450 () | 81181..82419 | - | 1239 | WP_000004159.1 | MFS transporter | - |
| HPS02_RS00455 () | 82416..83321 | - | 906 | WP_000219391.1 | hypothetical protein | ARG |
| HPS02_RS00460 () | 83443..84147 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HPS02_RS00465 () | 84298..85113 | + | 816 | WP_000018329.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| HPS02_RS00470 () | 85303..85971 | - | 669 | WP_044503635.1 | IS6 family transposase IS26 | Transposase |
| HPS02_RS00475 () | 86019..87212 | - | 1194 | Protein_94 | Tn3 family transposase TnpA_ISSba14 | Transposase |
| HPS02_RS00480 () | 87275..87979 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HPS02_RS00485 () | 88185..88493 | - | 309 | Protein_96 | IS5 family transposase ISThi1 | Transposase |
| HPS02_RS00490 () | 88835..89662 | + | 828 | WP_004153729.1 | Glutamine transport ATP-binding protein GlnQ | VF |
| HPS02_RS00495 () | 89659..90522 | + | 864 | WP_004152695.1 | phosphate/phosphite/phosphonate ABC transporter substrate-binding protein | - |
| HPS02_RS00500 () | 90531..91358 | + | 828 | WP_004152694.1 | phosphonate ABC transporter, permease protein PhnE | - |
| HPS02_RS00505 () | 91367..92377 | + | 1011 | WP_004152693.1 | phosphonate dehydrogenase PtxD | - |
| HPS02_RS00510 () | 92371..93240 | + | 870 | WP_004152692.1 | HTH-type transcriptional activator CmpR | VF |
| HPS02_RS00515 () | 93348..93867 | + | 520 | Protein_102 | IS5 family transposase ISPst7 | Transposase |
| HPS02_RS00520 () | 94449..95429 | - | 981 | WP_000019473.1 | IS5 family transposase ISKpn26 | Transposase |
| HPS02_RS00525 () | 95688..96385 | - | 698 | Protein_104 | IS1 family transposase IS1X2 | Transposase |
| HPS02_RS00530 () | 96570..96686 | - | 117 | Protein_105 | transposase domain-containing protein | - |
| HPS02_RS00535 () | 96631..96894 | - | 264 | WP_004118209.1 | transposase | - |
| HPS02_RS00540 () | 96909..97172 | + | 264 | WP_004118208.1 | hypothetical protein | - |
| HPS02_RS00545 () | 97416..97697 | + | 282 | WP_004152118.1 | helix-turn-helix domain-containing protein | - |
| HPS02_RS00550 () | 97732..98301 | + | 570 | WP_004152117.1 | Spore protein SP21 | VF |
| HPS02_RS00555 () | 98416..101211 | + | 2796 | WP_004152116.1 | ATP-dependent Clp protease ATP-binding subunit ClpC | VF |
| HPS02_RS00560 () | 101211..101408 | + | 198 | WP_004152115.1 | hypothetical protein | - |
| HPS02_RS00565 () | 101646..102395 | + | 750 | WP_009483782.1 | phosphate-starvation-inducible PsiE family protein | - |
| HPS02_RS00570 () | 102382..103344 | + | 963 | WP_004152113.1 | M48 family metalloprotease | - |
| HPS02_RS00575 () | 103432..104686 | + | 1255 | Protein_114 | IS3 family transposase ISKpn38 | Transposase |
| HPS02_RS00580 () | 105187..106533 | - | 1347 | WP_020314316.1 | ISNCY family transposase ISLad2 | Transposase |
| HPS02_RS00585 () | 106745..107227 | - | 483 | WP_003026803.1 | GNAT family N-acetyltransferase | Toxin Detail |
| HPS02_RS00590 () | 107215..107481 | - | 267 | WP_003026799.1 | DUF1778 domain-containing protein | Antitoxin Detail |
| HPS02_RS00595 () | 107657..107911 | - | 255 | WP_004152108.1 | hypothetical protein | - |
| HPS02_RS00600 () | 107987..108244 | - | 258 | WP_004152107.1 | hypothetical protein | - |
| HPS02_RS00605 () | 108293..108496 | - | 204 | WP_004152106.1 | hemolysin expression modulator Hha | - |
| HPS02_RS00610 () | 108530..108898 | - | 369 | WP_004152105.1 | hypothetical protein | - |
| HPS02_RS00615 () | 108942..109436 | - | 495 | WP_004152104.1 | DNA-binding protein | - |
| HPS02_RS00620 () | 109467..110042 | - | 576 | WP_004152103.1 | hypothetical protein | - |
| HPS02_RS00625 () | 110030..110299 | - | 270 | WP_004152102.1 | hypothetical protein | - |
| HPS02_RS00630 () | 110657..111007 | + | 351 | WP_004152101.1 | As(III)-sensing metalloregulatory transcriptional repressor ArsR | - |
| HPS02_RS00635 () | 111057..111419 | + | 363 | WP_004152100.1 | arsenite efflux transporter metallochaperone ArsD | - |
| HPS02_RS00640 () | 111437..113188 | + | 1752 | WP_004152099.1 | Arsenical pump-driving ATPase | VF |
| HPS02_RS00645 () | 113236..114525 | + | 1290 | WP_004152098.1 | arsenite efflux transporter membrane subunit ArsB | - |
| HPS02_RS00650 () | 114538..114963 | + | 426 | WP_004152097.1 | glutaredoxin-dependent arsenate reductase | - |
| HPS02_RS00655 () | 114996..115532 | - | 537 | WP_004152096.1 | GNAT family N-acetyltransferase | - |
| HPS02_RS00660 () | 115654..117404 | - | 1751 | Protein_131 | arsenical pump-driving ATPase | - |
| HPS02_RS00665 () | 117429..117791 | - | 363 | WP_004152095.1 | arsenic metallochaperone ArsD family protein | - |
| HPS02_RS00670 () | 117867..118412 | - | 546 | WP_004182005.1 | sigma-70 family RNA polymerase sigma factor | - |
| HPS02_RS00675 () | 118421..119134 | - | 714 | WP_004152093.1 | arsenical resistance protein ArsH | - |
| HPS02_RS00680 () | 119131..119457 | - | 327 | WP_004152092.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| HPS02_RS00685 () | 119789..120286 | + | 498 | WP_004152091.1 | GNAT family N-acetyltransferase | - |
| HPS02_RS00690 () | 120336..120845 | - | 510 | WP_031944101.1 | aquaporin | - |
| HPS02_RS00695 () | 120907..122527 | + | 1621 | Protein_138 | ISL3 family transposase ISEc38 | Transposase |
| HPS02_RS00700 () | 122588..122767 | + | 180 | WP_004152086.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| HPS02_RS00705 () | 122999..123433 | - | 435 | WP_004152085.1 | copper resistance system metallochaperone PcoE | - |
| HPS02_RS00710 () | 123650..125050 | - | 1401 | WP_004152084.1 | copper resistance membrane spanning protein PcoS | - |
| HPS02_RS00715 () | 125047..125727 | - | 681 | WP_001188930.1 | Transcriptional activator protein CopR | VF |
| HPS02_RS00720 () | 125782..126711 | - | 930 | WP_004118344.1 | copper resistance inner membrane protein PcoD | - |
| HPS02_RS00725 () | 126716..127096 | - | 381 | WP_000025662.1 | copper resistance system metallochaperone PcoC | - |
| HPS02_RS00730 () | 127136..128026 | - | 891 | WP_001378118.1 | copper resistance outer membrane transporter PcoB | - |
| HPS02_RS00735 () | 128032..129849 | - | 1818 | WP_004152083.1 | multicopper oxidase PcoA | - |
| HPS02_RS00740 () | 130083..130532 | + | 450 | WP_001023257.1 | copper resistance protein | - |
| HPS02_RS00745 () | 130821..131558 | + | 738 | WP_004118669.1 | Murein DD-endopeptidase MepM | VF |
| HPS02_RS00750 () | 131592..131789 | - | 198 | WP_000843497.1 | DUF2933 domain-containing protein | - |
| HPS02_RS00755 () | 131830..134277 | - | 2448 | WP_004098955.1 | Ag(+)-translocating P-type ATPase SilP | - |
| HPS02_RS00760 () | 134404..134844 | - | 441 | WP_000758228.1 | hypothetical protein | - |
| HPS02_RS00765 () | 134931..138077 | - | 3147 | WP_004098958.1 | Cu(+)/Ag(+) efflux RND transporter permease subunit SilA | - |
| HPS02_RS00770 () | 138088..139380 | - | 1293 | WP_004152079.1 | Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB | - |
| HPS02_RS00775 () | 139494..139847 | - | 354 | WP_001246153.1 | cation efflux system protein CusF | - |
| HPS02_RS00780 () | 139876..141261 | - | 1386 | WP_000475512.1 | Cation efflux system protein CusC | VF |
| HPS02_RS00785 () | 141451..142131 | + | 681 | WP_001572351.1 | Transcriptional regulatory protein CusR | VF |
| HPS02_RS00790 () | 142124..143599 | + | 1476 | WP_003032875.1 | copper/silver sensor histidine kinase SilS | - |
| HPS02_RS00795 () | 143850..144281 | + | 432 | WP_004178091.1 | silver-binding protein SilE | - |
| HPS02_RS00800 () | 144577..145119 | - | 543 | Protein_159 | ISL3 family transposase ISKpn25 | Transposase |
| HPS02_RS00805 () | 145135..145619 | - | 485 | Protein_160 | IS1 family transposase IS1X2 | Transposase |
| HPS02_RS00810 () | 145710..146917 | + | 1208 | WP_085955172.1 | IS3 family transposase ISEcl1 | Transposase |
| HPS02_RS00815 () | 147108..147805 | + | 698 | Protein_162 | IS1 family transposase IS1X2 | Transposase |
| HPS02_RS00820 () | 147957..149954 | + | 1998 | WP_004178088.1 | choline BCCT transporter BetT | - |
| HPS02_RS00825 () | 150017..151294 | + | 1278 | WP_004152070.1 | DUF2254 domain-containing protein | - |
| HPS02_RS00830 () | 152277..153731 | - | 1455 | WP_020444838.1 | putative cyclic di-GMP phosphodiesterase PdeB | VF |
| HPS02_RS00835 () | 154333..154590 | + | 258 | WP_004197688.1 | hypothetical protein | - |
| HPS02_RS00840 () | 155263..156231 | - | 969 | WP_011977741.1 | IS5 family transposase IS903B | Transposase |
| HPS02_RS00845 () | 156251..156562 | + | 312 | WP_071527918.1 | EAL domain-containing protein | - |
| HPS02_RS00850 () | 156589..157536 | - | 948 | WP_004152065.1 | sensor domain-containing diguanylate cyclase | - |
| HPS02_RS00855 () | 158680..159420 | + | 741 | WP_001515717.1 | tyrosine-type recombinase/integrase | - |
| HPS02_RS00860 () | 160137..161147 | - | 1011 | WP_004152063.1 | RepB family plasmid replication initiator protein | - |
| HPS02_RS00865 () | 161899..163065 | + | 1167 | WP_000523813.1 | Sporulation initiation inhibitor protein Soj | VF |
| HPS02_RS00870 () | 163065..164036 | + | 972 | WP_004152062.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| HPS02_RS00875 () | 165473..166671 | + | 1199 | Protein_174 | IS200-IS605 family transposase IS609 | Transposase |
| HPS02_RS00880 () | 166694..166909 | - | 216 | Protein_175 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| HPS02_RS00885 () | 166988..168259 | - | 1272 | WP_004152715.1 | Y-family DNA polymerase | - |
| HPS02_RS00890 () | 168259..168684 | - | 426 | WP_004178083.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|