MGE detailed information

MGE type: Conjugative plasmid        MGE length: 144645 bp
Accession: NZ_CP045990        Location: 1..144645         Organism: Klebsiella pneumoniae strain WCHKP35       Replicon: plasmid pKPC2_020035


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CEA74_RS26270 (CEA74_25900) 1..1020 + 1020 WP_020314728.1 plasmid replication initiator RepA -
CEA74_RS26275 (CEA74_25905) 2334..3032 + 699 WP_020804881.1 NYN domain-containing protein -
CEA74_RS26280 (CEA74_25910) 3327..4058 + 732 WP_020804880.1 HNH endonuclease -
CEA74_RS26285 (CEA74_25915) 4096..4374 + 279 WP_020314648.1 hypothetical protein -
CEA74_RS26290 (CEA74_25920) 4692..5303 + 612 WP_020804876.1 DUF2913 family protein -
CEA74_RS26295 (CEA74_25925) 5300..6253 - 954 WP_020314639.1 Recombination-promoting nuclease RpnA VF
CEA74_RS26300 (CEA74_25930) 6374..6640 - 267 WP_022644719.1 hypothetical protein -
CEA74_RS26305 (CEA74_25935) 6660..7280 - 621 WP_020314642.1 Tn3 family transposase TnpR_TnEc1 Transposase
CEA74_RS26310 (CEA74_25940) 7659..9092 + 1434 WP_075606933.1 DNA cytosine methyltransferase -
CEA74_RS26315 (CEA74_25945) 9127..10341 - 1215 WP_148237948.1 type II restriction endonuclease -
CEA74_RS26320 (CEA74_25950) 10649..13402 + 2754 WP_075606932.1 ABC transporter -
CEA74_RS26325 (CEA74_25955) 13508..14104 - 597 WP_032635043.1 Tn3 family transposase TnpR_ISYps3 Transposase
CEA74_RS26330 (CEA74_25960) 14644..15162 + 519 WP_022644913.1 hypothetical protein -
CEA74_RS26335 (CEA74_25965) 15508..16155 + 648 WP_022644912.1 AAA family ATPase -
CEA74_RS26340 (CEA74_25970) 16146..16421 + 276 WP_032072061.1 hypothetical protein -
CEA74_RS26345 (CEA74_25975) 16614..16814 - 201 WP_022644911.1 hypothetical protein -
CEA74_RS26350 (CEA74_25980) 16916..17677 - 762 Protein_17 translesion error-prone DNA polymerase V subunit UmuC -
CEA74_RS26355 (CEA74_25985) 17744..18448 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
CEA74_RS26360 (CEA74_25990) 18525..20966 - 2442 Protein_19 Tn3 family transposase TnpA_Tn3 Transposase
CEA74_RS26365 (CEA74_25995) 21129..21299 + 171 Protein_20 Tn3 family transposase TnpR_Tn3 Transposase
CEA74_RS26370 (CEA74_26000) 21360..22064 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
CEA74_RS26375 (CEA74_26005) 22089..22319 + 231 Protein_22 hypothetical protein -
CEA74_RS26380 22376..22507 + 132 Protein_23 ISNCY family transposase -
CEA74_RS26385 (CEA74_26010) 22504..23115 - 612 WP_000176305.1 DUF2913 family protein -
CEA74_RS26390 (CEA74_26015) 23169..23450 - 282 WP_001568067.1 hypothetical protein -
CEA74_RS26395 (CEA74_26020) 23840..24544 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
CEA74_RS26400 (CEA74_26025) 25565..25801 - 237 WP_142295024.1 hypothetical protein -
CEA74_RS26405 (CEA74_26030) 25807..26511 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
CEA74_RS26410 (CEA74_26035) 27055..27333 + 279 WP_013213990.1 hypothetical protein -
CEA74_RS26415 (CEA74_26040) 27444..27869 + 426 WP_013213989.1 antirestriction protein -
CEA74_RS26420 27997..28152 + 156 WP_013213988.1 hypothetical protein -
CEA74_RS26425 28198..28494 + 297 WP_013213987.1 transcriptional regulator -
CEA74_RS26430 (CEA74_26045) 28598..29479 + 882 Protein_33 IS1182 family transposase ISKpn6 Transposase
CEA74_RS26435 (CEA74_26050) 29729..30610 - 882 WP_004199234.1 Carbapenem-hydrolyzing beta-lactamase KPC ARG
CEA74_RS26440 (CEA74_26055) 30705..31307 - 603 WP_087497906.1 class A beta-lactamase -
CEA74_RS26445 (CEA74_26060) 31430..32410 - 981 WP_013213985.1 IS481 family transposase ISKpn27 Transposase
CEA74_RS26450 (CEA74_26065) 32533..32931 - 399 Protein_37 Tn3 family transposase TnpR_Tn3 Transposase
CEA74_RS26455 (CEA74_26070) 32983..33687 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
CEA74_RS26460 (CEA74_26075) 33763..35934 + 2172 Protein_39 Tn3 family transposase TnpA_Tn5403 Transposase
CEA74_RS26465 (CEA74_26080) 35969..37771 + 1803 Protein_40 Tn3 family transposase TnpA_IS3000 Transposase
CEA74_RS26470 (CEA74_26085) 37847..38248 + 402 Protein_41 Psp operon transcriptional activator VF
CEA74_RS26475 (CEA74_26090) 38342..38986 + 645 WP_014386481.1 Pentapeptide repeat protein ARG
CEA74_RS26480 (CEA74_26095) 39078..39809 - 732 Protein_43 putative oxidoreductase YghA VF
CEA74_RS26485 (CEA74_26100) 39859..40563 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
CEA74_RS26490 40627..40716 - 90 Protein_45 recombinase family protein -
CEA74_RS26495 (CEA74_26105) 41109..42122 - 1014 WP_000845048.1 IS91 family transposase ISAzo26 Transposase
CEA74_RS26500 (CEA74_26110) 42278..42751 + 474 WP_004201280.1 Dihydrofolate reductase type 1 ARG
CEA74_RS26505 42972..43088 + 117 Protein_48 hypothetical protein Relaxase
CEA74_RS26510 43198..43263 + 66 Protein_49 hypothetical protein Relaxase
CEA74_RS26515 (CEA74_26120) 43381..44145 + 765 WP_001389365.1 IS6 family transposase IS6100 Transposase
CEA74_RS26520 (CEA74_26125) 44337..45551 + 1215 WP_004098817.1 type II site-specific deoxyribonuclease -
CEA74_RS26525 (CEA74_26130) 45585..47018 - 1434 WP_001288432.1 DNA cytosine methyltransferase -
CEA74_RS26530 (CEA74_26135) 47171..47875 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
CEA74_RS26535 (CEA74_26140) 47912..48811 - 900 WP_087497909.1 plasmid replication initiator RepA -
CEA74_RS26540 (CEA74_26145) 48804..49355 - 552 WP_022631532.1 plasmid replication initiator RepA -
CEA74_RS26545 (CEA74_26155) 49637..49906 - 270 WP_022631531.1 replication regulatory protein RepA -
CEA74_RS26550 (CEA74_26160) 50042..50593 - 552 WP_015065550.1 Phospholipase D VF
CEA74_RS26555 (CEA74_26165) 50697..51005 - 309 WP_015065549.1 hypothetical protein -
CEA74_RS26560 (CEA74_26170) 51002..51652 - 651 WP_004152382.1 DUF2726 domain-containing protein -
CEA74_RS26565 (CEA74_26175) 51708..52352 - 645 WP_015065546.1 hypothetical protein -
CEA74_RS26570 (CEA74_26180) 52402..53004 - 603 WP_015065545.1 PIN domain-containing protein -
CEA74_RS26575 (CEA74_26185) 53165..53758 - 594 WP_015065544.1 fertility inhibition protein FinO -
CEA74_RS26580 (CEA74_26190) 53914..54639 - 726 WP_015065543.1 type-F conjugative transfer system pilin acetylase TraX -
CEA74_RS26585 (CEA74_26195) 54719..59977 - 5259 WP_015065542.1 Multifunctional conjugation protein TraI Relaxase
CEA74_RS26590 (CEA74_26200) 59977..62289 - 2313 WP_015065541.1 type IV conjugative transfer system coupling protein TraD -
CEA74_RS26595 62418..63107 - 690 WP_015065540.1 hypothetical protein -
CEA74_RS26600 (CEA74_26210) 63299..64030 - 732 WP_032329926.1 conjugal transfer complement resistance protein TraT -
CEA74_RS26605 (CEA74_26215) 64339..64863 - 525 WP_015065538.1 hypothetical protein -
CEA74_RS26610 (CEA74_26220) 64874..67717 - 2844 WP_015065537.1 conjugal transfer mating-pair stabilization protein TraG -
CEA74_RS26615 (CEA74_26225) 67717..69087 - 1371 WP_004178055.1 conjugal transfer pilus assembly protein TraH -
CEA74_RS26620 (CEA74_26230) 69074..69502 - 429 WP_015065560.1 hypothetical protein -
CEA74_RS26625 (CEA74_26235) 69495..70067 - 573 WP_023292147.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
CEA74_RS26630 (CEA74_26240) 70039..70278 - 240 WP_004152687.1 type-F conjugative transfer system pilin chaperone TraQ -
CEA74_RS26635 (CEA74_26245) 70289..71041 - 753 WP_020803149.1 type-F conjugative transfer system pilin assembly protein TraF -
CEA74_RS26640 (CEA74_26250) 71062..71388 - 327 WP_004152676.1 hypothetical protein -
CEA74_RS26645 (CEA74_26255) 71401..71649 - 249 WP_004152675.1 hypothetical protein -
CEA74_RS26650 (CEA74_26260) 71627..71881 - 255 WP_004152674.1 conjugal transfer protein TrbE -
CEA74_RS26655 (CEA74_26265) 71913..73868 - 1956 WP_030003482.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
CEA74_RS26660 (CEA74_26270) 73927..74565 - 639 WP_015065635.1 type-F conjugative transfer system pilin assembly protein TrbC -
CEA74_RS26665 (CEA74_26275) 74578..75567 - 990 WP_011977785.1 conjugal transfer pilus assembly protein TraU -
CEA74_RS26670 (CEA74_26280) 75564..75953 - 390 WP_015065532.1 hypothetical protein -
CEA74_RS26675 (CEA74_26285) 75995..76621 - 627 WP_009309871.1 type-F conjugative transfer system protein TraW -
CEA74_RS26680 (CEA74_26290) 76621..77010 - 390 WP_004152506.1 type-F conjugative transfer system protein TrbI -
CEA74_RS26685 (CEA74_26295) 77010..79649 - 2640 WP_004152505.1 type IV secretion system protein TraC -
CEA74_RS26690 (CEA74_26300) 79721..80119 - 399 WP_011977783.1 hypothetical protein -
CEA74_RS26695 80127..80369 - 243 WP_004158946.1 hypothetical protein -
CEA74_RS26700 (CEA74_26310) 80561..80965 - 405 WP_004152503.1 hypothetical protein -
CEA74_RS26705 (CEA74_26315) 81032..81343 - 312 WP_004152502.1 hypothetical protein -
CEA74_RS26710 (CEA74_26320) 81344..81562 - 219 WP_004152501.1 hypothetical protein -
CEA74_RS26715 (CEA74_26325) 81668..82078 - 411 WP_032329942.1 hypothetical protein -
CEA74_RS26720 (CEA74_26330) 82210..82794 - 585 WP_015065529.1 type IV conjugative transfer system lipoprotein TraV -
CEA74_RS26725 (CEA74_26335) 82908..84332 - 1425 WP_004194260.1 F-type conjugal transfer pilus assembly protein TraB -
CEA74_RS26730 (CEA74_26340) 84332..85072 - 741 WP_015065528.1 type-F conjugative transfer system secretin TraK -
CEA74_RS26735 (CEA74_26345) 85059..85625 - 567 WP_004144423.1 type IV conjugative transfer system protein TraE -
CEA74_RS26740 (CEA74_26350) 85645..85950 - 306 WP_004144424.1 type IV conjugative transfer system protein TraL -
CEA74_RS26745 (CEA74_26355) 85964..86332 - 369 WP_004194426.1 type IV conjugative transfer system pilin TraA -
CEA74_RS26750 (CEA74_26360) 86397..86600 - 204 WP_171486139.1 TraY domain-containing protein -
CEA74_RS26755 (CEA74_26365) 86733..87452 - 720 WP_015065526.1 hypothetical protein -
CEA74_RS26760 (CEA74_26370) 87652..88068 - 417 WP_072145360.1 conjugal transfer relaxosome DNA-binding protein TraM -
CEA74_RS26765 (CEA74_26375) 88459..88944 + 486 WP_015065525.1 hypothetical protein VF
CEA74_RS26770 (CEA74_26380) 88977..89306 - 330 WP_015065524.1 DUF5983 family protein -
CEA74_RS26775 (CEA74_26385) 89339..90161 - 823 Protein_102 DUF932 domain-containing protein -
CEA74_RS26780 (CEA74_26390) 90990..91391 - 402 WP_015065522.1 helix-turn-helix domain-containing protein -
CEA74_RS26785 (CEA74_26395) 91392..91670 - 279 WP_020801586.1 helix-turn-helix transcriptional regulator -
CEA74_RS26790 (CEA74_26400) 91660..91980 - 321 WP_015065521.1 type II toxin-antitoxin system RelE/ParE family toxin -
CEA74_RS26795 (CEA74_26405) 92061..92285 - 225 WP_014343499.1 hypothetical protein -
CEA74_RS26800 (CEA74_26410) 92296..92508 - 213 WP_019706020.1 hypothetical protein -
CEA74_RS26805 (CEA74_26415) 92569..92925 - 357 WP_019706019.1 hypothetical protein -
CEA74_RS26810 (CEA74_26420) 93766..94083 - 318 WP_015065519.1 hypothetical protein -
CEA74_RS26815 (CEA74_26425) 94098..94448 - 351 WP_040245917.1 hypothetical protein -
CEA74_RS26820 (CEA74_26430) 94445..94717 - 273 WP_040245921.1 hypothetical protein -
CEA74_RS26825 (CEA74_26435) 95410..95529 - 120 WP_159376494.1 type I toxin-antitoxin system Hok family toxin -
CEA74_RS26830 95474..95626 - 153 WP_004150508.1 DUF5431 family protein -
CEA74_RS26835 (CEA74_26440) 95796..96170 - 375 WP_001568060.1 hypothetical protein -
CEA74_RS26840 (CEA74_26445) 96226..96552 - 327 WP_013023807.1 hypothetical protein -
CEA74_RS26845 (CEA74_26450) 96549..97277 - 729 WP_001568058.1 plasmid SOS inhibition protein A -
CEA74_RS26850 (CEA74_26455) 97274..97705 - 432 WP_001568057.1 conjugation system SOS inhibitor PsiB -
CEA74_RS26855 (CEA74_26460) 97750..99807 - 2058 WP_112080919.1 ParB/RepB/Spo0J family partition protein -
CEA74_RS26860 (CEA74_26465) 99877..100125 - 249 WP_004182058.1 DUF905 domain-containing protein -
CEA74_RS26865 (CEA74_26470) 100174..100716 - 543 WP_014343512.1 single-stranded DNA-binding protein -
CEA74_RS26870 (CEA74_26475) 101549..102112 - 564 WP_014343514.1 methyltransferase -
CEA74_RS26875 (CEA74_26480) 102160..103515 - 1356 WP_243500793.1 DUF3560 domain-containing protein -
CEA74_RS26880 (CEA74_26485) 103567..103797 - 231 WP_001568051.1 hypothetical protein -
CEA74_RS26885 (CEA74_26490) 103889..104116 - 228 WP_001568050.1 hypothetical protein -
CEA74_RS26890 (CEA74_26495) 104796..105116 - 321 WP_001568049.1 hypothetical protein -
CEA74_RS26895 (CEA74_26500) 105151..105405 - 255 WP_011977779.1 DNA polymerase III subunit theta -
CEA74_RS26900 105607..105783 - 177 Protein_127 hypothetical protein -
CEA74_RS26905 (CEA74_26510) 105826..106332 - 507 WP_013214014.1 antirestriction protein ArdA -
CEA74_RS26910 (CEA74_26515) 106375..106803 - 429 WP_001568045.1 antirestriction protein -
CEA74_RS26915 (CEA74_26520) 107484..108251 - 768 WP_013214013.1 hypothetical protein -
CEA74_RS26920 (CEA74_26525) 108305..108724 - 420 WP_001568043.1 DUF1380 domain-containing protein -
CEA74_RS26925 (CEA74_26530) 108734..108955 - 222 WP_001568042.1 hypothetical protein -
CEA74_RS26930 (CEA74_26535) 108955..109656 - 702 WP_001568041.1 DNA methylase -
CEA74_RS26935 109728..109897 - 170 Protein_134 hypothetical protein -
CEA74_RS26940 (CEA74_26540) 110093..110323 - 231 WP_001568040.1 hypothetical protein -
CEA74_RS26945 (CEA74_26545) 110386..111057 - 672 WP_013214012.1 plasmid partitioning/stability family protein -
CEA74_RS26950 (CEA74_26550) 111060..112031 - 972 WP_004152353.1 plasmid segregation protein ParM -
CEA74_RS26955 (CEA74_26555) 112265..112696 + 432 WP_001568036.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
CEA74_RS26960 (CEA74_26560) 112696..113967 + 1272 WP_013214011.1 Y-family DNA polymerase -
CEA74_RS26965 (CEA74_26565) 114049..115023 - 975 WP_011977819.1 ParB family protein -
CEA74_RS26970 (CEA74_26570) 115023..116228 - 1206 WP_011977818.1 AAA family ATPase -
CEA74_RS26975 (CEA74_26575) 117338..118204 - 867 WP_004118283.1 replication initiation protein -
CEA74_RS26980 118740..118853 + 114 WP_014343462.1 hypothetical protein -
CEA74_RS26985 (CEA74_26580) 118982..119239 + 258 WP_013214010.1 hypothetical protein -
CEA74_RS26990 (CEA74_26585) 119285..120064 - 780 WP_013214009.1 site-specific integrase -
CEA74_RS26995 (CEA74_26590) 120248..121252 - 1005 WP_011977814.1 hypothetical protein -
CEA74_RS27000 (CEA74_26595) 121282..121485 - 204 WP_011977813.1 hypothetical protein -
CEA74_RS27005 (CEA74_26600) 121531..122052 - 522 WP_013214008.1 hypothetical protein -
CEA74_RS27010 (CEA74_26605) 122110..122502 - 393 WP_011977811.1 hypothetical protein -
CEA74_RS27015 (CEA74_26610) 122539..123483 - 945 WP_011977810.1 hypothetical protein -
CEA74_RS27020 (CEA74_26615) 124071..124301 + 231 WP_001261276.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin Detail
CEA74_RS27025 (CEA74_26620) 124298..124714 + 417 WP_032425563.1 type II toxin-antitoxin system VapC family toxin Toxin Detail
CEA74_RS27030 (CEA74_26625) 124755..125633 - 879 WP_064182004.1 restriction endonuclease -
CEA74_RS27035 (CEA74_26630) 126295..127572 + 1278 WP_009309915.1 HlyD family secretion protein -
CEA74_RS27040 (CEA74_26635) 127562..129670 + 2109 WP_032427226.1 peptidase domain-containing ABC transporter -
CEA74_RS27045 (CEA74_26640) 129670..130305 + 636 WP_009309912.1 type II CAAX endopeptidase family protein -
CEA74_RS27050 (CEA74_26645) 130413..130757 - 345 WP_009309911.1 hypothetical protein -
CEA74_RS27055 (CEA74_26650) 131324..131572 + 249 WP_019725036.1 hypothetical protein -
CEA74_RS27060 (CEA74_26655) 131569..132141 + 573 WP_015065504.1 hypothetical protein -
CEA74_RS27065 (CEA74_26660) 132172..132666 + 495 WP_009310053.1 hypothetical protein -
CEA74_RS27070 (CEA74_26665) 132710..133078 + 369 WP_015065502.1 hypothetical protein -
CEA74_RS27075 (CEA74_26670) 133112..133315 + 204 WP_019725040.1 HHA domain-containing protein -
CEA74_RS27080 (CEA74_26675) 133329..133559 + 231 WP_019725034.1 hypothetical protein -
CEA74_RS27085 (CEA74_26680) 133603..133797 - 195 WP_019725033.1 hypothetical protein -
CEA74_RS27090 (CEA74_26685) 134231..134554 - 324 WP_019725650.1 hypothetical protein -
CEA74_RS27095 (CEA74_26690) 134627..135622 - 996 WP_019725651.1 hypothetical protein -
CEA74_RS27100 (CEA74_26695) 135919..136569 - 651 WP_015065500.1 SOS response-associated peptidase -
CEA74_RS27105 (CEA74_26700) 136616..137014 - 399 Protein_168 Tn3 family transposase TnpR_ISThsp9 Transposase
CEA74_RS27110 (CEA74_26705) 137070..137774 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
CEA74_RS27115 (CEA74_26710) 137888..138505 - 618 Protein_170 replication protein -
CEA74_RS27120 (CEA74_26715) 138897..139457 + 561 WP_001161490.1 Tn3 family transposase TnpR_TnAs1 Transposase
CEA74_RS27125 (CEA74_26720) 139461..142427 + 2967 WP_001138014.1 Tn3 family transposase TnpA_TnAs1 Transposase
CEA74_RS27130 (CEA74_26725) 142460..142993 + 534 Protein_173 DUF2726 domain-containing protein -
CEA74_RS27135 (CEA74_26730) 142990..143298 + 309 WP_004098858.1 hypothetical protein -
CEA74_RS27140 (CEA74_26735) 143393..143950 + 558 WP_020315133.1 Phospholipase D VF
CEA74_RS27145 (CEA74_26740) 144083..144337 + 255 WP_004098862.1 replication regulatory protein RepA -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance