MGE detailed information
MGE type: Conjugative plasmid MGE length: 169226 bp
Accession: NZ_CP042521 Location: 1..169226 Organism: Klebsiella pneumoniae strain C2 Replicon: plasmid pC2_001
Accession: NZ_CP042521 Location: 1..169226 Organism: Klebsiella pneumoniae strain C2 Replicon: plasmid pC2_001
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| FR744_RS25770 () | 1..1011 | + | 1011 | WP_000200071.1 | RepB family plasmid replication initiator protein | - |
| FR744_RS25780 () | 1728..2468 | - | 741 | WP_001515717.1 | tyrosine-type recombinase/integrase | - |
| FR744_RS25785 () | 3612..4559 | + | 948 | WP_023328266.1 | sensor domain-containing diguanylate cyclase | - |
| FR744_RS25790 () | 4586..6469 | - | 1884 | WP_077269298.1 | EAL domain-containing protein | - |
| FR744_RS25795 () | 6999..7121 | + | 123 | WP_139788384.1 | small membrane protein | - |
| FR744_RS25800 () | 7412..8047 | + | 636 | WP_064185732.1 | hypothetical protein | - |
| FR744_RS25805 () | 8163..8819 | + | 657 | WP_064279360.1 | hypothetical protein | - |
| FR744_RS25810 () | 9345..9602 | - | 258 | WP_023328269.1 | hypothetical protein | - |
| FR744_RS25815 () | 10206..11660 | + | 1455 | WP_071836382.1 | EAL domain-containing protein | - |
| FR744_RS25820 () | 12194..12724 | - | 531 | Protein_9 | hypothetical protein | - |
| FR744_RS25825 () | 12776..13126 | - | 351 | WP_023328272.1 | hypothetical protein | - |
| FR744_RS25835 () | 13315..13729 | - | 415 | Protein_11 | hypothetical protein | - |
| FR744_RS25840 () | 13686..13916 | + | 231 | WP_001261282.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| FR744_RS25845 () | 13913..14329 | + | 417 | WP_001044770.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| FR744_RS25850 () | 14403..15965 | + | 1563 | WP_004206609.1 | AAA family ATPase | - |
| FR744_RS25855 () | 15950..16972 | + | 1023 | WP_000361404.1 | helicase UvrD | - |
| FR744_RS25860 () | 17510..18424 | + | 915 | WP_031592169.1 | HNH endonuclease | - |
| FR744_RS25865 () | 18610..18960 | - | 351 | WP_064279361.1 | DUF305 domain-containing protein | - |
| FR744_RS25870 () | 19104..19535 | - | 432 | WP_023302802.1 | silver-binding protein SilE | - |
| FR744_RS25875 () | 19786..21261 | - | 1476 | WP_003032875.1 | copper/silver sensor histidine kinase SilS | - |
| FR744_RS25880 () | 21254..21934 | - | 681 | WP_001572351.1 | copper/silver response regulator transcription factor SilR | - |
| FR744_RS25885 () | 22124..23509 | + | 1386 | WP_023292107.1 | Cu(+)/Ag(+) efflux RND transporter outer membrane channel SilC | - |
| FR744_RS25890 () | 23538..23900 | + | 363 | WP_004213578.1 | cation efflux system protein CusF | - |
| FR744_RS25895 () | 24014..25306 | + | 1293 | WP_048270279.1 | Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB | - |
| FR744_RS25900 () | 25317..28463 | + | 3147 | WP_080925886.1 | Cu(+)/Ag(+) efflux RND transporter permease subunit SilA | - |
| FR744_RS25905 () | 28550..28990 | + | 441 | WP_000758228.1 | hypothetical protein | - |
| FR744_RS25910 () | 29117..31558 | + | 2442 | WP_064279363.1 | Ag(+)-translocating P-type ATPase SilP | - |
| FR744_RS25915 () | 31599..31796 | + | 198 | WP_000843497.1 | DUF2933 domain-containing protein | - |
| FR744_RS25920 () | 31830..32567 | - | 738 | WP_000287501.1 | peptidoglycan DD-metalloendopeptidase family protein | - |
| FR744_RS25925 () | 32856..33305 | - | 450 | WP_001023257.1 | copper resistance protein | - |
| FR744_RS25930 () | 33538..35355 | + | 1818 | WP_000925242.1 | multicopper oxidase PcoA | - |
| FR744_RS25935 () | 35361..36251 | + | 891 | WP_151641777.1 | copper resistance outer membrane transporter PcoB | - |
| FR744_RS25940 () | 36291..36671 | + | 381 | WP_000025662.1 | copper resistance system metallochaperone PcoC | - |
| FR744_RS25945 () | 36676..37605 | + | 930 | WP_004118344.1 | copper resistance inner membrane protein PcoD | - |
| FR744_RS25950 () | 37660..38340 | + | 681 | WP_001188930.1 | copper response regulator transcription factor PcoR | - |
| FR744_RS25955 () | 38337..39737 | + | 1401 | WP_002436614.1 | copper resistance membrane spanning protein PcoS | - |
| FR744_RS25960 () | 39953..40387 | + | 435 | WP_004118347.1 | hypothetical protein | - |
| FR744_RS25970 () | 40766..40864 | - | 99 | WP_004118688.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| FR744_RS25975 () | 40851..41030 | - | 180 | WP_004118349.1 | type II toxin-antitoxin system ParD family antitoxin | - |
| FR744_RS25980 () | 41344..41607 | + | 264 | WP_004118691.1 | hypothetical protein | - |
| FR744_RS25985 () | 41604..42170 | + | 567 | WP_029497543.1 | hypothetical protein | - |
| FR744_RS25990 () | 42201..42695 | + | 495 | WP_009310053.1 | hypothetical protein | - |
| FR744_RS25995 () | 42739..43107 | + | 369 | WP_009310054.1 | hypothetical protein | - |
| FR744_RS26000 () | 43138..43341 | + | 204 | WP_004098931.1 | hemolysin expression modulator Hha | - |
| FR744_RS26005 () | 43390..43647 | + | 258 | WP_004098928.1 | hypothetical protein | - |
| FR744_RS26010 () | 43723..43977 | + | 255 | WP_004118702.1 | hypothetical protein | - |
| FR744_RS26015 () | 44137..45391 | - | 1255 | Protein_46 | IS3 family transposase | - |
| FR744_RS26020 () | 45479..46441 | - | 963 | WP_004152113.1 | M48 family metalloprotease | - |
| FR744_RS26025 () | 46428..46916 | - | 489 | WP_004152114.1 | phosphate-starvation-inducible PsiE family protein | - |
| FR744_RS26040 () | 47414..47611 | - | 198 | WP_004152115.1 | hypothetical protein | - |
| FR744_RS26045 () | 47611..50406 | - | 2796 | WP_004152116.1 | heat shock survival AAA family ATPase ClpK | - |
| FR744_RS26050 () | 50539..51108 | - | 570 | WP_004152117.1 | small heat shock protein sHSP20 | - |
| FR744_RS26055 () | 51143..51424 | - | 282 | WP_004152118.1 | helix-turn-helix domain-containing protein | - |
| FR744_RS26060 () | 51668..51931 | - | 264 | WP_004118208.1 | hypothetical protein | - |
| FR744_RS26065 () | 51946..52209 | + | 264 | WP_004118209.1 | transposase | - |
| FR744_RS26070 () | 52154..52270 | + | 117 | Protein_55 | transposase domain-containing protein | - |
| FR744_RS26075 () | 52455..53152 | + | 698 | Protein_56 | IS1 family transposase | - |
| FR744_RS26080 () | 53360..54367 | - | 1008 | WP_004181997.1 | formamidase | - |
| FR744_RS26085 () | 54403..55092 | - | 690 | WP_004181996.1 | urea ABC transporter ATP-binding subunit UrtE | - |
| FR744_RS26090 () | 55103..55852 | - | 750 | WP_004181995.1 | urea ABC transporter ATP-binding protein UrtD | - |
| FR744_RS26095 () | 55849..56964 | - | 1116 | WP_004181994.1 | urea ABC transporter permease subunit UrtC | - |
| FR744_RS26100 () | 56974..57900 | - | 927 | WP_004181993.1 | urea ABC transporter permease subunit UrtB | - |
| FR744_RS26105 () | 57957..59147 | - | 1191 | WP_004197507.1 | urea ABC transporter substrate-binding protein | - |
| FR744_RS26110 () | 59452..62832 | + | 3381 | WP_004181991.1 | response regulator | - |
| FR744_RS26115 () | 62795..63715 | + | 921 | WP_004181990.1 | response regulator | - |
| FR744_RS26120 () | 63767..64231 | + | 465 | Protein_65 | transposase | - |
| FR744_RS26125 () | 64275..64655 | - | 381 | Protein_66 | transposase family protein | - |
| FR744_RS26130 () | 64712..65680 | - | 969 | WP_072143344.1 | IS5 family transposase | - |
| FR744_RS26135 () | 65849..66350 | - | 502 | Protein_68 | DUF2913 family protein | - |
| FR744_RS26150 () | 66970..67415 | - | 446 | Protein_69 | creatininase family protein | - |
| FR744_RS26155 () | 67591..69324 | - | 1734 | WP_004118832.1 | ABC transporter ATP-binding protein | - |
| FR744_RS26160 () | 69332..70279 | - | 948 | WP_004118225.1 | acetamidase/formamidase family protein | - |
| FR744_RS26165 () | 70324..71928 | - | 1605 | WP_004152278.1 | ABC transporter substrate-binding protein | - |
| FR744_RS26170 () | 71941..72861 | - | 921 | WP_004118227.1 | ABC transporter permease | - |
| FR744_RS26175 () | 72861..73709 | - | 849 | WP_004118228.1 | ABC transporter permease | - |
| FR744_RS26180 () | 73706..74299 | - | 594 | WP_004118229.1 | ANTAR domain-containing protein | - |
| FR744_RS26185 () | 74296..75423 | - | 1128 | WP_004118840.1 | transporter substrate-binding protein | - |
| FR744_RS26190 () | 75708..75875 | - | 168 | WP_004118231.1 | integrase | - |
| FR744_RS26195 () | 76017..76502 | + | 486 | Protein_78 | transposase | - |
| FR744_RS26200 () | 76978..77499 | + | 522 | WP_004197062.1 | RNA polymerase sigma factor FecI | - |
| FR744_RS26205 () | 77496..78449 | + | 954 | WP_004197067.1 | fec operon regulator FecR | - |
| FR744_RS26210 () | 78542..80866 | + | 2325 | WP_029498502.1 | Fe(3+) dicitrate transport protein FecA | - |
| FR744_RS26215 () | 80911..81813 | + | 903 | WP_023157913.1 | Fe(3+) dicitrate ABC transporter substrate-binding protein FecB | - |
| FR744_RS26220 () | 81810..82808 | + | 999 | WP_004118243.1 | iron-dicitrate ABC transporter permease FecC | - |
| FR744_RS26225 () | 82805..83761 | + | 957 | WP_004118246.1 | Fe(3+) dicitrate ABC transporter permease subunit FecD | - |
| FR744_RS26230 () | 83762..84529 | + | 768 | WP_004152282.1 | Fe(3+) dicitrate ABC transporter ATP-binding protein FecE | - |
| FR744_RS26235 () | 84628..84921 | + | 294 | WP_004118251.1 | IS66 family insertion sequence element accessory protein TnpB | - |
| FR744_RS26240 () | 84996..85223 | + | 228 | Protein_87 | IS66 family transposase | - |
| FR744_RS26245 () | 85252..85494 | - | 243 | WP_071527925.1 | EAL domain-containing protein | - |
| FR744_RS26250 () | 85792..86796 | - | 1005 | WP_000427614.1 | IS110-like element IS5075 family transposase | - |
| FR744_RS26255 () | 87200..88209 | - | 1010 | Protein_90 | zinc-binding alcohol dehydrogenase family protein | - |
| FR744_RS26265 () | 88670..89752 | + | 1083 | WP_016831235.1 | DNA-binding transcriptional repressor LacI | - |
| FR744_RS26270 () | 89874..92948 | + | 3075 | WP_004182121.1 | beta-galactosidase | - |
| FR744_RS26275 () | 93000..94253 | + | 1254 | WP_004182120.1 | lactose permease | - |
| FR744_RS26280 () | 94319..94459 | + | 141 | Protein_94 | galactoside O-acetyltransferase | - |
| FR744_RS26285 () | 94474..95170 | - | 697 | Protein_95 | IS1 family transposase | - |
| FR744_RS26290 () | 95359..95619 | - | 261 | WP_023313931.1 | DUF2534 family protein | - |
| FR744_RS26295 () | 95676..97739 | - | 2064 | WP_004182117.1 | TonB-dependent copper receptor | - |
| FR744_RS26300 () | 97822..98241 | - | 420 | WP_015065566.1 | DUF2946 domain-containing protein | - |
| FR744_RS26310 () | 99184..99468 | + | 285 | WP_000537151.1 | IS3 family transposase | - |
| FR744_RS26315 () | 99465..100319 | + | 855 | WP_077254108.1 | IS3 family transposase | - |
| FR744_RS26320 () | 100705..101025 | + | 321 | WP_004197483.1 | hypothetical protein | - |
| FR744_RS26340 () | 102390..103247 | - | 858 | WP_023307528.1 | incFII family plasmid replication initiator RepA | - |
| FR744_RS26345 () | 103240..103317 | - | 78 | WP_004171457.1 | RepA leader peptide Tap | - |
| FR744_RS26350 () | 103534..103812 | - | 279 | WP_004199332.1 | replication regulatory protein RepA | - |
| FR744_RS26355 () | 104132..104610 | - | 479 | Protein_105 | phospholipase D family protein | - |
| FR744_RS26360 () | 104951..105230 | - | 280 | Protein_106 | bacteriocin immunity protein | - |
| FR744_RS26365 () | 105232..106758 | - | 1527 | Protein_107 | klebicin B-related nuclease bacteriocin | - |
| FR744_RS26370 () | 106817..107785 | - | 969 | WP_165451746.1 | IS5-like element IS903B family transposase | - |
| FR744_RS26375 () | 107819..108619 | - | 801 | Protein_109 | klebicin B-related nuclease bacteriocin | - |
| FR744_RS26380 () | 108975..109520 | + | 546 | WP_151641779.1 | hypothetical protein | - |
| FR744_RS26385 () | 109735..110082 | - | 348 | WP_151641780.1 | hypothetical protein | - |
| FR744_RS26390 () | 110102..110698 | - | 597 | WP_023307531.1 | fertility inhibition protein FinO | - |
| FR744_RS26395 () | 110855..111580 | - | 726 | WP_023284651.1 | type-F conjugative transfer system pilin acetylase TraX | - |
| FR744_RS26400 () | 111660..116921 | - | 5262 | WP_023307532.1 | conjugative transfer relaxase/helicase TraI | - |
| FR744_RS26405 () | 116921..119230 | - | 2310 | Protein_115 | type IV conjugative transfer system coupling protein TraD | - |
| FR744_RS26410 () | 119592..120209 | - | 618 | WP_015065642.1 | hypothetical protein | - |
| FR744_RS26415 () | 120175..120323 | - | 149 | Protein_117 | traT complement resistance domain protein | - |
| FR744_RS26420 () | 120513..121040 | - | 528 | WP_024623127.1 | conjugal transfer protein TraS | - |
| FR744_RS26425 () | 121046..123895 | - | 2850 | WP_151641781.1 | conjugal transfer mating pair stabilization protein TraG | - |
| FR744_RS26430 () | 123895..125274 | - | 1380 | WP_011977731.1 | conjugal transfer protein TraH | - |
| FR744_RS26435 () | 125252..125695 | - | 444 | WP_015065638.1 | F-type conjugal transfer protein TrbF | - |
| FR744_RS26440 () | 125740..126297 | - | 558 | WP_004152678.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| FR744_RS26445 () | 126269..126508 | - | 240 | WP_004144400.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| FR744_RS26450 () | 126519..127271 | - | 753 | WP_015065637.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| FR744_RS26455 () | 127292..127618 | - | 327 | WP_004152685.1 | hypothetical protein | - |
| FR744_RS26465 () | 127846..128082 | - | 237 | WP_023307536.1 | conjugal transfer protein TrbE | - |
| FR744_RS26470 () | 128114..130069 | - | 1956 | WP_015065636.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| FR744_RS26475 () | 130128..130766 | - | 639 | WP_015065635.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| FR744_RS26480 () | 130779..131771 | - | 993 | WP_004178057.1 | conjugal transfer pilus assembly protein TraU | - |
| FR744_RS26485 () | 131782..132408 | - | 627 | WP_015065633.1 | type-F conjugative transfer system protein TraW | - |
| FR744_RS26490 () | 132408..132797 | - | 390 | WP_004152506.1 | type-F conjugative transfer system protein TrbI | - |
| FR744_RS26495 () | 132797..135436 | - | 2640 | WP_016528865.1 | type IV secretion system protein TraC | - |
| FR744_RS26500 () | 135508..135906 | - | 399 | WP_015065631.1 | hypothetical protein | - |
| FR744_RS26505 () | 135931..136335 | - | 405 | WP_023320104.1 | hypothetical protein | - |
| FR744_RS26510 () | 136402..136719 | - | 318 | WP_015065629.1 | hypothetical protein | - |
| FR744_RS26515 () | 136720..136938 | - | 219 | WP_004171484.1 | hypothetical protein | - |
| FR744_RS26520 () | 136962..137252 | - | 291 | WP_032426790.1 | hypothetical protein | - |
| FR744_RS26525 () | 137281..137460 | - | 180 | WP_071609111.1 | hypothetical protein | - |
| FR744_RS26530 () | 137835..138404 | - | 570 | WP_015065628.1 | type IV conjugative transfer system lipoprotein TraV | - |
| FR744_RS27890 () | 138424..138579 | - | 156 | WP_153587559.1 | hypothetical protein | - |
| FR744_RS26535 () | 138604..139029 | - | 426 | WP_015065627.1 | conjugal transfer protein TraP | - |
| FR744_RS26540 () | 139022..140446 | - | 1425 | WP_040228261.1 | conjugal transfer protein TraB | - |
| FR744_RS26545 () | 140446..141186 | - | 741 | WP_004152497.1 | type-F conjugative transfer system secretin TraK | - |
| FR744_RS26550 () | 141173..141739 | - | 567 | WP_004152602.1 | type IV conjugative transfer system protein TraE | - |
| FR744_RS26555 () | 141759..142064 | - | 306 | WP_015065625.1 | type IV conjugative transfer system protein TraL | - |
| FR744_RS26560 () | 142078..142446 | - | 369 | WP_004178060.1 | type IV conjugative transfer system pilin TraA | - |
| FR744_RS26565 () | 142500..142871 | - | 372 | WP_004208838.1 | TraY domain-containing protein | - |
| FR744_RS26570 () | 142955..143650 | - | 696 | WP_015065624.1 | transcriptional regulator TraJ family protein | - |
| FR744_RS26575 () | 143857..144249 | - | 393 | WP_004206766.1 | relaxosome protein TraM | - |
| FR744_RS26580 () | 144684..145169 | + | 486 | WP_001568108.1 | transglycosylase SLT domain-containing protein | - |
| FR744_RS26585 () | 145202..145516 | - | 315 | WP_001568110.1 | hypothetical protein | - |
| FR744_RS26590 () | 145564..146385 | - | 822 | WP_015065622.1 | DUF945 domain-containing protein | - |
| FR744_RS26610 () | 147219..147632 | - | 414 | WP_004182074.1 | helix-turn-helix domain-containing protein | - |
| FR744_RS26615 () | 147633..147911 | - | 279 | WP_004152721.1 | helix-turn-helix domain-containing protein | - |
| FR744_RS26620 () | 147901..148221 | - | 321 | WP_004152720.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| FR744_RS26625 () | 148302..148526 | - | 225 | WP_004152719.1 | hypothetical protein | - |
| FR744_RS26630 () | 148537..148749 | - | 213 | WP_021313197.1 | hypothetical protein | - |
| FR744_RS26635 () | 148810..149166 | - | 357 | WP_004152717.1 | hypothetical protein | - |
| FR744_RS26645 () | 149802..150152 | - | 351 | WP_015065620.1 | hypothetical protein | - |
| FR744_RS26650 () | 150149..150421 | - | 273 | WP_047062072.1 | hypothetical protein | - |
| FR744_RS26655 () | 151114..151275 | - | 162 | WP_004118124.1 | type I toxin-antitoxin system Hok family toxin | - |
| FR744_RS26665 () | 151503..151877 | - | 375 | WP_047062073.1 | hypothetical protein | - |
| FR744_RS26670 () | 151933..152259 | - | 327 | WP_047062074.1 | hypothetical protein | - |
| FR744_RS26675 () | 152256..152984 | - | 729 | WP_047062075.1 | plasmid SOS inhibition protein A | - |
| FR744_RS26680 () | 152981..153412 | - | 432 | WP_004194235.1 | conjugation system SOS inhibitor PsiB | - |
| FR744_RS26685 () | 153457..155514 | - | 2058 | WP_151641782.1 | ParB/RepB/Spo0J family partition protein | - |
| FR744_RS26690 () | 155584..155832 | - | 249 | WP_047062077.1 | DUF905 domain-containing protein | - |
| FR744_RS26695 () | 155881..156423 | - | 543 | WP_151641783.1 | single-stranded DNA-binding protein | - |
| FR744_RS26710 () | 157257..157820 | - | 564 | WP_047062065.1 | methyltransferase | - |
| FR744_RS26715 () | 157868..159223 | - | 1356 | WP_023320091.1 | DUF3560 domain-containing protein | - |
| FR744_RS26720 () | 159275..159505 | - | 231 | WP_001568051.1 | hypothetical protein | - |
| FR744_RS26725 () | 159597..159824 | - | 228 | WP_047062066.1 | hypothetical protein | - |
| FR744_RS26735 () | 160609..160926 | - | 318 | WP_004118473.1 | hypothetical protein | - |
| FR744_RS26740 () | 160961..161215 | - | 255 | WP_023320090.1 | DNA polymerase III subunit theta | - |
| FR744_RS26745 () | 161452..161877 | - | 426 | WP_047062067.1 | antirestriction protein | - |
| FR744_RS26760 () | 162400..162630 | - | 231 | WP_047062068.1 | hypothetical protein | - |
| FR744_RS26765 () | 162843..163268 | + | 426 | WP_047062069.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| FR744_RS26770 () | 163268..164539 | + | 1272 | WP_004118485.1 | Y-family DNA polymerase | - |
| FR744_RS26775 () | 164618..164869 | + | 252 | WP_004118488.1 | plasmid stabilization protein | - |
| FR744_RS26780 () | 164923..165228 | + | 306 | WP_016156495.1 | hypothetical protein | - |
| FR744_RS26795 () | 166338..167309 | - | 972 | WP_047062010.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| FR744_RS26800 () | 167309..168475 | - | 1167 | WP_000523813.1 | plasmid-partitioning protein SopA | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|