MGE detailed information
MGE type: Conjugative plasmid MGE length: 148625 bp
Accession: NZ_CP040030 Location: 1..148625 Organism: Klebsiella pneumoniae strain KPC160121 Replicon: plasmid pQnr-L121
Accession: NZ_CP040030 Location: 1..148625 Organism: Klebsiella pneumoniae strain KPC160121 Replicon: plasmid pQnr-L121
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| FDK25_RS28230 () | 1..1011 | + | 1011 | WP_004152063.1 | RepB family plasmid replication initiator protein | - |
| FDK25_RS28235 () | 1728..2468 | - | 741 | WP_001515717.1 | tyrosine-type recombinase/integrase | - |
| FDK25_RS28240 () | 3612..4559 | + | 948 | WP_004152065.1 | sensor domain-containing diguanylate cyclase | - |
| FDK25_RS28245 () | 4586..4897 | - | 312 | WP_071527918.1 | EAL domain-containing protein | - |
| FDK25_RS28250 () | 4917..5885 | + | 969 | WP_011977741.1 | IS5 family transposase IS903B | Transposase |
| FDK25_RS28255 () | 7418..8872 | + | 1455 | WP_020444838.1 | putative cyclic di-GMP phosphodiesterase PdeB | VF |
| FDK25_RS28260 () | 9855..11132 | - | 1278 | WP_004152070.1 | DUF2254 domain-containing protein | - |
| FDK25_RS28265 () | 11195..13192 | - | 1998 | WP_004178088.1 | choline BCCT transporter BetT | - |
| FDK25_RS28270 () | 13344..14041 | - | 698 | Protein_8 | IS1 family transposase IS1X2 | Transposase |
| FDK25_RS28280 () | 15530..16014 | + | 485 | Protein_10 | IS1 family transposase IS1X2 | Transposase |
| FDK25_RS28285 () | 16030..16572 | + | 543 | Protein_11 | ISL3 family transposase ISKpn25 | Transposase |
| FDK25_RS28290 () | 16868..17299 | - | 432 | WP_004178091.1 | silver-binding protein SilE | - |
| FDK25_RS28295 () | 17550..19025 | - | 1476 | WP_003032875.1 | copper/silver sensor histidine kinase SilS | - |
| FDK25_RS28300 () | 19018..19698 | - | 681 | WP_001572351.1 | Transcriptional regulatory protein CusR | VF |
| FDK25_RS28305 () | 19888..21273 | + | 1386 | WP_000475512.1 | Cation efflux system protein CusC | VF |
| FDK25_RS28310 () | 21302..21655 | + | 354 | WP_001246153.1 | cation efflux system protein CusF | - |
| FDK25_RS28315 () | 21769..23061 | + | 1293 | WP_004152079.1 | Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB | - |
| FDK25_RS28320 () | 23072..26218 | + | 3147 | WP_004098958.1 | Cu(+)/Ag(+) efflux RND transporter permease subunit SilA | - |
| FDK25_RS28325 () | 26305..26745 | + | 441 | WP_000758228.1 | hypothetical protein | - |
| FDK25_RS28330 () | 26872..29319 | + | 2448 | WP_004098955.1 | Ag(+)-translocating P-type ATPase SilP | - |
| FDK25_RS28335 () | 29360..29557 | + | 198 | WP_000843497.1 | DUF2933 domain-containing protein | - |
| FDK25_RS28340 () | 29591..30328 | - | 738 | WP_004118669.1 | Murein DD-endopeptidase MepM | VF |
| FDK25_RS28345 () | 30617..31066 | - | 450 | WP_001023257.1 | copper resistance protein | - |
| FDK25_RS28350 () | 31300..33117 | + | 1818 | WP_000925242.1 | multicopper oxidase PcoA | - |
| FDK25_RS28355 () | 33123..34013 | + | 891 | WP_001378118.1 | copper resistance outer membrane transporter PcoB | - |
| FDK25_RS28360 () | 34053..34433 | + | 381 | WP_000025662.1 | copper resistance system metallochaperone PcoC | - |
| FDK25_RS28365 () | 34438..35367 | + | 930 | WP_004118344.1 | copper resistance inner membrane protein PcoD | - |
| FDK25_RS28370 () | 35422..36102 | + | 681 | WP_001188930.1 | Transcriptional activator protein CopR | VF |
| FDK25_RS28375 () | 36099..37499 | + | 1401 | WP_004152084.1 | copper resistance membrane spanning protein PcoS | - |
| FDK25_RS28380 () | 37716..38150 | + | 435 | WP_004152085.1 | copper resistance system metallochaperone PcoE | - |
| FDK25_RS28385 () | 38382..38561 | - | 180 | WP_004152086.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| FDK25_RS28390 () | 38622..40242 | - | 1621 | Protein_32 | ISL3 family transposase ISEc38 | Transposase |
| FDK25_RS28395 () | 40304..40813 | + | 510 | WP_031944101.1 | aquaporin | - |
| FDK25_RS28400 () | 40863..41360 | - | 498 | WP_004152091.1 | GNAT family N-acetyltransferase | - |
| FDK25_RS28405 () | 41692..42018 | + | 327 | WP_004152092.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| FDK25_RS28410 () | 42015..42728 | + | 714 | WP_004152093.1 | arsenical resistance protein ArsH | - |
| FDK25_RS28415 () | 42737..43282 | + | 546 | WP_004182005.1 | sigma-70 family RNA polymerase sigma factor | - |
| FDK25_RS28420 () | 43358..43720 | + | 363 | WP_004152095.1 | arsenic metallochaperone ArsD family protein | - |
| FDK25_RS28425 () | 43745..45495 | + | 1751 | Protein_39 | arsenical pump-driving ATPase | - |
| FDK25_RS28430 () | 45617..46153 | + | 537 | WP_004152096.1 | GNAT family N-acetyltransferase | - |
| FDK25_RS28435 () | 46186..46611 | - | 426 | WP_004152097.1 | glutaredoxin-dependent arsenate reductase | - |
| FDK25_RS28440 () | 46624..47913 | - | 1290 | WP_004152098.1 | arsenite efflux transporter membrane subunit ArsB | - |
| FDK25_RS28445 () | 47961..49712 | - | 1752 | WP_004152099.1 | Arsenical pump-driving ATPase | VF |
| FDK25_RS28450 () | 49730..50092 | - | 363 | WP_004152100.1 | arsenite efflux transporter metallochaperone ArsD | - |
| FDK25_RS28455 () | 50142..50492 | - | 351 | WP_004152101.1 | As(III)-sensing metalloregulatory transcriptional repressor ArsR | - |
| FDK25_RS28460 () | 50850..51119 | + | 270 | WP_004152102.1 | hypothetical protein | - |
| FDK25_RS28465 () | 51107..51682 | + | 576 | WP_004152103.1 | hypothetical protein | - |
| FDK25_RS28470 () | 51713..52207 | + | 495 | WP_004152104.1 | DNA-binding protein | - |
| FDK25_RS28475 () | 52251..52619 | + | 369 | WP_004152105.1 | hypothetical protein | - |
| FDK25_RS28480 () | 52653..52856 | + | 204 | WP_004152106.1 | hemolysin expression modulator Hha | - |
| FDK25_RS28485 () | 52905..53162 | + | 258 | WP_004152107.1 | hypothetical protein | - |
| FDK25_RS28490 () | 53238..53492 | + | 255 | WP_004152108.1 | hypothetical protein | - |
| FDK25_RS28495 () | 53668..53934 | + | 267 | WP_003026799.1 | DUF1778 domain-containing protein | Antitoxin Detail |
| FDK25_RS28500 () | 53922..54404 | + | 483 | WP_003026803.1 | GNAT family N-acetyltransferase | Toxin Detail |
| FDK25_RS28505 () | 54605..56008 | + | 1404 | WP_001567368.1 | ISNCY family transposase ISKpn21 | Transposase |
| FDK25_RS28510 () | 56037..56669 | - | 633 | WP_001567369.1 | hypothetical protein | - |
| FDK25_RS28515 () | 57104..58108 | - | 1005 | Protein_57 | IS110 family transposase IS4321R | Transposase |
| FDK25_RS28520 () | 58187..58744 | - | 558 | WP_003100847.1 | Tn3 family transposase TnpR_ISPa38 | Transposase |
| FDK25_RS28525 () | 58738..59109 | - | 372 | WP_003100853.1 | hypothetical protein | - |
| FDK25_RS28530 () | 59106..59606 | - | 501 | WP_003100856.1 | hypothetical protein | - |
| FDK25_RS28535 () | 59603..59929 | - | 327 | WP_003100858.1 | hypothetical protein | - |
| FDK25_RS28540 () | 60184..60540 | - | 357 | WP_000215515.1 | cupin domain-containing protein | - |
| FDK25_RS28545 () | 60530..60922 | - | 393 | WP_108714626.1 | DUF86 domain-containing protein | - |
| FDK25_RS28550 () | 60928..61632 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| FDK25_RS28555 () | 61756..62046 | - | 291 | WP_001247892.1 | nucleotidyltransferase | - |
| FDK25_RS28560 () | 62245..62949 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| FDK25_RS28565 () | 63001..63135 | - | 135 | Protein_67 | dihydropteroate synthase | - |
| FDK25_RS28570 () | 63129..63464 | - | 336 | WP_052238321.1 | ethidium bromide resistance protein | - |
| FDK25_RS28575 () | 63357..63722 | + | 366 | WP_025999322.1 | hydrogenase maturation nickel metallochaperone HypA | - |
| FDK25_RS28580 () | 63726..64601 | - | 876 | WP_004193231.1 | LysR family transcriptional regulator AmpR | - |
| FDK25_RS28585 () | 64712..65851 | + | 1140 | WP_004236386.1 | Beta-lactamase | ARG |
| FDK25_RS28590 () | 66046..66840 | + | 795 | Protein_72 | alpha-2-macroglobulin family protein | - |
| FDK25_RS28600 () | 67202..67432 | - | 231 | WP_004193241.1 | phage shock protein PspD | - |
| FDK25_RS28605 () | 67441..67800 | - | 360 | WP_004193243.1 | envelope stress response membrane protein PspC | - |
| FDK25_RS28610 () | 67800..68024 | - | 225 | WP_004193245.1 | envelope stress response membrane protein PspB | - |
| FDK25_RS28615 () | 68079..68747 | - | 669 | WP_003020532.1 | phage shock protein PspA | - |
| FDK25_RS28620 () | 68903..69892 | + | 990 | WP_017900991.1 | Psp operon transcriptional activator | VF |
| FDK25_RS28625 () | 69975..70619 | + | 645 | WP_017900990.1 | Pentapeptide repeat protein | ARG |
| FDK25_RS28630 () | 70715..71623 | - | 909 | WP_004193260.1 | putative oxidoreductase YghA | VF |
| FDK25_RS28635 () | 71800..72378 | - | 579 | WP_004193262.1 | 2-oxo-tetronate isomerase | - |
| FDK25_RS28640 () | 72326..72772 | - | 447 | WP_004193264.1 | DUF421 domain-containing protein | - |
| FDK25_RS28645 () | 72782..73285 | - | 504 | WP_004193267.1 | hypothetical protein | - |
| FDK25_RS28650 () | 73417..73809 | + | 393 | WP_004193269.1 | YdeI family stress tolerance OB fold protein | - |
| FDK25_RS28655 () | 74110..75753 | + | 1644 | WP_004193272.1 | peptide ABC transporter substrate-binding protein SapA | - |
| FDK25_RS28660 () | 75750..76508 | + | 759 | Protein_85 | peptide ABC transporter permease SapB | - |
| FDK25_RS28665 () | 76551..77255 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| FDK25_RS28670 () | 77267..77386 | - | 120 | WP_108714627.1 | hypothetical protein | - |
| FDK25_RS28690 () | 78572..79429 | - | 858 | WP_004152292.1 | incFII family plasmid replication initiator RepA | - |
| FDK25_RS28695 () | 79422..79499 | - | 78 | WP_004171457.1 | RepA leader peptide Tap | - |
| FDK25_RS28700 () | 79716..79994 | - | 279 | WP_004199332.1 | replication regulatory protein RepA | - |
| FDK25_RS28705 () | 80315..80794 | - | 480 | WP_009485932.1 | Phospholipase D | VF |
| FDK25_RS28710 () | 81135..81413 | - | 279 | WP_004152296.1 | bacteriocin immunity protein | - |
| FDK25_RS28715 () | 81415..83736 | - | 2322 | WP_004178051.1 | klebicin B-related nuclease bacteriocin | - |
| FDK25_RS28720 () | 84093..84638 | + | 546 | WP_004178052.1 | hypothetical protein | - |
| FDK25_RS28725 () | 84853..85200 | - | 348 | WP_004152301.1 | hypothetical protein | - |
| FDK25_RS28730 () | 85220..85816 | - | 597 | WP_004178053.1 | fertility inhibition protein FinO | - |
| FDK25_RS28735 () | 85974..86699 | - | 726 | WP_004152303.1 | type-F conjugative transfer system pilin acetylase TraX | - |
| FDK25_RS28740 () | 86779..92040 | - | 5262 | WP_004153029.1 | Multifunctional conjugation protein TraI | Relaxase |
| FDK25_RS28745 () | 92040..94349 | - | 2310 | Protein_99 | type IV conjugative transfer system coupling protein TraD | - |
| FDK25_RS28750 () | 94709..95440 | - | 732 | WP_004152629.1 | complement resistance protein TraT | - |
| FDK25_RS28755 () | 95630..96157 | - | 528 | WP_004153030.1 | hypothetical protein | - |
| FDK25_RS28760 () | 96163..99012 | - | 2850 | WP_004178054.1 | conjugal transfer mating pair stabilization protein TraG | - |
| FDK25_RS28765 () | 99012..100382 | - | 1371 | WP_004178055.1 | conjugal transfer protein TraH | - |
| FDK25_RS28770 () | 100369..100797 | - | 429 | WP_004152689.1 | hypothetical protein | - |
| FDK25_RS28775 () | 100790..101362 | - | 573 | WP_004152688.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| FDK25_RS28780 () | 101334..101573 | - | 240 | WP_004152687.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| FDK25_RS28785 () | 101584..102336 | - | 753 | WP_004152686.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| FDK25_RS28790 () | 102357..102683 | - | 327 | WP_004152685.1 | hypothetical protein | - |
| FDK25_RS28795 () | 102911..103147 | - | 237 | WP_004152683.1 | conjugal transfer protein TrbE | - |
| FDK25_RS28800 () | 103179..105134 | - | 1956 | WP_004153093.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| FDK25_RS28805 () | 105182..105820 | - | 639 | WP_004152682.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| FDK25_RS28810 () | 105833..106825 | - | 993 | WP_004178057.1 | conjugal transfer pilus assembly protein TraU | - |
| FDK25_RS28815 () | 106836..107462 | - | 627 | WP_004152590.1 | type-F conjugative transfer system protein TraW | - |
| FDK25_RS28820 () | 107462..107851 | - | 390 | WP_004152591.1 | type-F conjugative transfer system protein TrbI | - |
| FDK25_RS28825 () | 107851..110490 | - | 2640 | WP_004152592.1 | type IV secretion system protein TraC | - |
| FDK25_RS28830 () | 110562..110960 | - | 399 | WP_004153071.1 | hypothetical protein | - |
| FDK25_RS28835 () | 111256..111660 | - | 405 | WP_004152594.1 | hypothetical protein | - |
| FDK25_RS28840 () | 111727..112044 | - | 318 | WP_004152595.1 | hypothetical protein | - |
| FDK25_RS28845 () | 112045..112263 | - | 219 | WP_004171484.1 | hypothetical protein | - |
| FDK25_RS28850 () | 112287..112577 | - | 291 | WP_004152596.1 | hypothetical protein | - |
| FDK25_RS28855 () | 112582..112992 | - | 411 | WP_004152597.1 | lipase chaperone | - |
| FDK25_RS28860 () | 113124..113693 | - | 570 | WP_004152598.1 | type IV conjugative transfer system lipoprotein TraV | - |
| FDK25_RS28865 () | 113716..114312 | - | 597 | WP_004152599.1 | conjugal transfer protein TraP | - |
| FDK25_RS28870 () | 114305..115729 | - | 1425 | WP_004152600.1 | conjugal transfer protein TraB | - |
| FDK25_RS28875 () | 115729..116469 | - | 741 | WP_004152601.1 | type-F conjugative transfer system secretin TraK | - |
| FDK25_RS28880 () | 116456..117022 | - | 567 | WP_004152602.1 | type IV conjugative transfer system protein TraE | - |
| FDK25_RS28885 () | 117042..117347 | - | 306 | WP_004178059.1 | type IV conjugative transfer system protein TraL | - |
| FDK25_RS28890 () | 117361..117729 | - | 369 | WP_004178060.1 | type IV conjugative transfer system pilin TraA | - |
| FDK25_RS28895 () | 117783..118154 | - | 372 | WP_004208838.1 | TraY domain-containing protein | - |
| FDK25_RS28900 () | 118238..118924 | - | 687 | WP_011977735.1 | transcriptional regulator TraJ family protein | - |
| FDK25_RS28905 () | 119147..119539 | - | 393 | WP_004178062.1 | relaxosome protein TraM | - |
| FDK25_RS28910 () | 119973..120458 | + | 486 | WP_004178063.1 | hypothetical protein | VF |
| FDK25_RS28915 () | 120491..120820 | - | 330 | WP_011977736.1 | hypothetical protein | - |
| FDK25_RS28920 () | 120853..121674 | - | 822 | WP_004178064.1 | DUF945 domain-containing protein | - |
| FDK25_RS28940 () | 122508..122921 | - | 414 | WP_004152722.1 | helix-turn-helix domain-containing protein | - |
| FDK25_RS28945 () | 122922..123200 | - | 279 | WP_004152721.1 | helix-turn-helix domain-containing protein | - |
| FDK25_RS28950 () | 123190..123510 | - | 321 | WP_004152720.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| FDK25_RS28955 () | 123591..123815 | - | 225 | WP_004152719.1 | hypothetical protein | - |
| FDK25_RS28960 () | 123826..124038 | - | 213 | WP_004152718.1 | hypothetical protein | - |
| FDK25_RS28965 () | 124099..124455 | - | 357 | WP_004152717.1 | hypothetical protein | - |
| FDK25_RS28980 () | 125091..125441 | - | 351 | WP_004152758.1 | hypothetical protein | - |
| FDK25_RS28985 () | 125438..125710 | - | 273 | WP_004152759.1 | hypothetical protein | - |
| FDK25_RS29000 () | 126410..126571 | - | 162 | WP_004118124.1 | type I toxin-antitoxin system Hok family toxin | - |
| FDK25_RS29005 () | 126643..127722 | + | 1080 | WP_004220208.1 | IS481 family transposase ISKpn28 | Transposase |
| FDK25_RS29010 () | 127900..128274 | - | 375 | WP_004152638.1 | hypothetical protein | - |
| FDK25_RS29015 () | 128330..128656 | - | 327 | WP_004152639.1 | hypothetical protein | - |
| FDK25_RS29020 () | 128653..129381 | - | 729 | WP_004152640.1 | plasmid SOS inhibition protein A | - |
| FDK25_RS29025 () | 129378..129809 | - | 432 | WP_004152641.1 | conjugation system SOS inhibitor PsiB | - |
| FDK25_RS29030 () | 129876..131912 | - | 2037 | WP_004178066.1 | ParB/RepB/Spo0J family partition protein | - |
| FDK25_RS29035 () | 131982..132230 | - | 249 | WP_004152643.1 | DUF905 domain-containing protein | - |
| FDK25_RS29040 () | 132279..132821 | - | 543 | WP_004152644.1 | single-stranded DNA-binding protein | - |
| FDK25_RS29050 () | 133597..134160 | - | 564 | WP_004152645.1 | methyltransferase | - |
| FDK25_RS29055 () | 134208..135563 | - | 1356 | WP_004178068.1 | DUF3560 domain-containing protein | - |
| FDK25_RS29060 () | 135615..135845 | - | 231 | WP_004198570.1 | hypothetical protein | - |
| FDK25_RS29065 () | 135937..136164 | - | 228 | WP_004178072.1 | hypothetical protein | - |
| FDK25_RS29080 () | 136946..137263 | - | 318 | WP_004118473.1 | hypothetical protein | - |
| FDK25_RS29085 () | 137298..137552 | - | 255 | WP_004152754.1 | DNA polymerase III subunit theta | - |
| FDK25_RS29090 () | 137789..138214 | - | 426 | WP_004118478.1 | antirestriction protein | - |
| FDK25_RS29095 () | 138735..138965 | - | 231 | WP_004152753.1 | hypothetical protein | - |
| FDK25_RS29100 () | 139199..140686 | - | 1488 | WP_004178082.1 | group II intron reverse transcriptase/maturase | - |
| FDK25_RS29105 () | 141089..141514 | + | 426 | WP_004178083.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| FDK25_RS29110 () | 141514..142785 | + | 1272 | WP_004152715.1 | Y-family DNA polymerase | - |
| FDK25_RS29115 () | 142864..143079 | + | 216 | Protein_163 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| FDK25_RS29120 () | 143102..144300 | - | 1199 | Protein_164 | IS200-IS605 family transposase IS609 | Transposase |
| FDK25_RS29125 () | 145737..146708 | - | 972 | WP_004152062.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| FDK25_RS29130 () | 146708..147874 | - | 1167 | WP_000523813.1 | Sporulation initiation inhibitor protein Soj | VF |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|