MGE detailed information
MGE type: Integrative_Conjugative_Elements MGE length: 146694 bp
Accession: NZ_CP035259 Location: 926301..1072994 Organism: Streptococcus pneumoniae strain TVO_1901926 Replicon: chromosome
Accession: NZ_CP035259 Location: 926301..1072994 Organism: Streptococcus pneumoniae strain TVO_1901926 Replicon: chromosome
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EQH21_RS04675 (EQH21_04925) | 921538..922761 | - | 1224 | WP_000222046.1 | peptidase T | - |
| EQH21_RS04680 (EQH21_04930) | 922916..924010 | + | 1095 | WP_000709247.1 | ferrochelatase | - |
| EQH21_RS04685 (EQH21_04935) | 924052..924429 | - | 378 | WP_000916795.1 | large conductance mechanosensitive channel protein MscL | - |
| EQH21_RS04690 (EQH21_04940) | 924511..924942 | - | 432 | WP_054362861.1 | GtrA family protein | - |
| EQH21_RS04695 (EQH21_04945) | 925065..925574 | + | 510 | WP_000737071.1 | QueT transporter family protein | - |
| EQH21_RS04705 (EQH21_04960) | 926332..927408 | + | 1077 | WP_000542471.1 | aspartate-semialdehyde dehydrogenase | - |
| EQH21_RS04710 (EQH21_04965) | 927464..928399 | + | 936 | WP_000121627.1 | 4-hydroxy-tetrahydrodipicolinate synthase | - |
| EQH21_RS04715 (EQH21_04970) | 928446..929819 | - | 1374 | WP_000632719.1 | tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE | - |
| EQH21_RS04720 (EQH21_04975) | 929956..930138 | - | 183 | WP_001117401.1 | 4-oxalocrotonate tautomerase | - |
| EQH21_RS04725 (EQH21_04980) | 930261..930860 | + | 600 | WP_000068153.1 | thymidine kinase | - |
| EQH21_RS04730 (EQH21_04985) | 930850..931329 | + | 480 | WP_000151335.1 | GNAT family N-acetyltransferase | - |
| EQH21_RS04735 (EQH21_04990) | 931339..932418 | + | 1080 | WP_001028801.1 | peptide chain release factor 1 | - |
| EQH21_RS04740 (EQH21_04995) | 932418..933257 | + | 840 | WP_000761916.1 | peptide chain release factor N(5)-glutamine methyltransferase | - |
| EQH21_RS04745 (EQH21_05000) | 933241..933843 | + | 603 | WP_000990345.1 | L-threonylcarbamoyladenylate synthase | - |
| EQH21_RS04750 (EQH21_05005) | 933845..934276 | + | 432 | WP_000942936.1 | GNAT family N-acetyltransferase | - |
| EQH21_RS04755 (EQH21_05010) | 934338..935594 | + | 1257 | WP_000575522.1 | serine hydroxymethyltransferase | - |
| EQH21_RS04760 (EQH21_05015) | 935602..936576 | + | 975 | WP_000356094.1 | nucleoid-associated protein | - |
| EQH21_RS04765 (EQH21_05020) | 936576..937190 | + | 615 | WP_000476384.1 | cell wall hydrolase Pmp23 | - |
| EQH21_RS04770 (EQH21_05025) | 937264..938238 | + | 975 | WP_001227738.1 | DUF1002 domain-containing protein | - |
| EQH21_RS04775 (EQH21_05030) | 938312..939937 | + | 1626 | WP_000914568.1 | 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD | - |
| EQH21_RS04780 (EQH21_05035) | 940151..940429 | + | 279 | WP_000710807.1 | hypothetical protein | - |
| EQH21_RS04785 (EQH21_05040) | 940675..940893 | + | 219 | WP_001207345.1 | helix-turn-helix transcriptional regulator | - |
| EQH21_RS04790 (EQH21_05050) | 941286..942311 | + | 1026 | WP_061640859.1 | iron-siderophore ABC transporter substrate-binding protein | - |
| EQH21_RS04795 (EQH21_05055) | 942301..943308 | + | 1008 | WP_001244693.1 | Ferric enterobactin transport system permease protein FepD | VF |
| EQH21_RS04800 (EQH21_05060) | 943308..944315 | + | 1008 | WP_001180361.1 | putative siderophore transport system permease protein YfhA | VF |
| EQH21_RS04805 (EQH21_05065) | 944315..945109 | + | 795 | WP_000677520.1 | putative siderophore transport system ATP-binding protein YusV | VF |
| EQH21_RS04810 | 945260..945444 | + | 185 | Protein_958 | IS3 family transposase | - |
| EQH21_RS04815 (EQH21_05070) | 945497..945922 | + | 426 | WP_074192621.1 | restriction endonuclease subunit S | - |
| EQH21_RS04820 (EQH21_05075) | 945978..946295 | + | 318 | WP_000968321.1 | DUF3847 domain-containing protein | - |
| EQH21_RS04825 | 946609..947043 | + | 435 | Protein_961 | IS1380 family transposase ISSpn5 | Transposase |
| EQH21_RS04830 (EQH21_05080) | 947266..948612 | + | 1347 | WP_001811769.1 | IS1380 family transposase ISSpn5 | Transposase |
| EQH21_RS04835 (EQH21_05085) | 948803..949957 | + | 1155 | Protein_963 | MobA/MobL family protein | - |
| EQH21_RS04840 (EQH21_05090) | 950339..950866 | + | 528 | WP_000606578.1 | PcfB family protein | - |
| EQH21_RS04845 (EQH21_05095) | 950993..951721 | + | 729 | WP_000224685.1 | phage replisome organizer N-terminal domain-containing protein | - |
| EQH21_RS04850 (EQH21_05100) | 952405..952566 | + | 162 | WP_000368174.1 | hypothetical protein | - |
| EQH21_RS04855 (EQH21_05105) | 952658..954337 | + | 1680 | WP_000031842.1 | Tn3 family transposase TnpR_ISAcsp1 | Transposase |
| EQH21_RS04860 (EQH21_05110) | 954605..955171 | + | 567 | WP_000234983.1 | hypothetical protein | - |
| EQH21_RS04865 (EQH21_05115) | 955492..955680 | + | 189 | WP_000179769.1 | hypothetical protein | - |
| EQH21_RS04870 (EQH21_05120) | 955742..956500 | + | 759 | WP_000262042.1 | ATP-grasp domain-containing protein | - |
| EQH21_RS04875 (EQH21_05125) | 956558..957412 | + | 855 | WP_000900020.1 | ADP-ribosylglycohydrolase family protein | - |
| EQH21_RS04880 (EQH21_05130) | 957524..958408 | + | 885 | WP_000710115.1 | diacylglycerol kinase family lipid kinase | - |
| EQH21_RS04885 (EQH21_05140) | 958571..960189 | + | 1619 | Protein_973 | glycoside hydrolase family 13 protein | - |
| EQH21_RS04890 (EQH21_05145) | 960464..960919 | + | 456 | WP_000500474.1 | hypothetical protein | - |
| EQH21_RS04895 (EQH21_05150) | 961364..961840 | + | 477 | WP_000579613.1 | type II toxin-antitoxin system antitoxin PezA | Antitoxin Detail |
| EQH21_RS04900 (EQH21_05155) | 961840..962601 | + | 762 | WP_000405362.1 | type II toxin-antitoxin system toxin PezT | Toxin Detail |
| EQH21_RS04905 | 962629..962919 | + | 291 | WP_001213954.1 | hypothetical protein | - |
| EQH21_RS04910 | 962913..963785 | + | 873 | WP_001811494.1 | hypothetical protein | - |
| EQH21_RS04915 (EQH21_05170) | 964604..964963 | + | 360 | WP_000003750.1 | SAG1252 family conjugative relaxosome accessory protein | - |
| EQH21_RS04920 (EQH21_05175) | 964973..965338 | + | 366 | WP_000263054.1 | plasmid mobilization relaxosome protein MobC | - |
| EQH21_RS04925 (EQH21_05180) | 965325..967175 | + | 1851 | WP_000261801.1 | SAG1250 family conjugative relaxase | - |
| EQH21_RS04930 (EQH21_05185) | 967431..968863 | + | 1433 | Protein_982 | IS1182 family transposase | - |
| EQH21_RS04935 (EQH21_05195) | 969762..970061 | + | 300 | WP_001138382.1 | hypothetical protein | - |
| EQH21_RS04940 (EQH21_05200) | 970120..970794 | + | 675 | WP_000903082.1 | CatA-like O-acetyltransferase | - |
| EQH21_RS04945 (EQH21_05205) | 970862..972499 | + | 1638 | WP_061640861.1 | methionine--tRNA ligase | - |
| EQH21_RS04950 (EQH21_05210) | 972600..973367 | + | 768 | Protein_986 | tyrosine-protein phosphatase | - |
| EQH21_RS04955 (EQH21_05215) | 974384..975376 | + | 993 | WP_024266136.1 | ABC transporter ATP-binding protein NatA | VF |
| EQH21_RS04960 (EQH21_05220) | 975378..976196 | + | 819 | WP_000164265.1 | ABC-2 family transporter protein | - |
| EQH21_RS04965 (EQH21_05225) | 976198..976983 | + | 786 | WP_000760754.1 | ABC transporter permease | - |
| EQH21_RS04970 (EQH21_05230) | 977362..978612 | - | 1251 | Protein_990 | IS110 family transposase | - |
| EQH21_RS04975 (EQH21_05235) | 979059..979262 | + | 204 | WP_000275922.1 | helix-turn-helix transcriptional regulator | - |
| EQH21_RS04980 | 979393..979545 | + | 153 | WP_001812617.1 | hypothetical protein | - |
| EQH21_RS04985 (EQH21_05240) | 979712..981505 | + | 1794 | WP_054362863.1 | hypothetical protein ; Integrase | Integrase |
| EQH21_RS04990 (EQH21_05245) | 981589..982197 | + | 609 | WP_000662946.1 | Type 1 glutamine amidotransferase-like domain-containing protein | - |
| EQH21_RS04995 (EQH21_05250) | 982446..982727 | + | 282 | WP_001811421.1 | aminoglycoside phosphotransferase | - |
| EQH21_RS05000 (EQH21_05255) | 982832..983161 | + | 330 | Protein_996 | IS5 family transposase IS1381A | Transposase |
| EQH21_RS05005 (EQH21_05260) | 983289..984518 | + | 1230 | WP_000703362.1 | FtsW/RodA/SpoVE family cell cycle protein | - |
| EQH21_RS05010 (EQH21_05265) | 984538..987234 | + | 2697 | WP_000058204.1 | phosphoenolpyruvate carboxylase | - |
| EQH21_RS05015 (EQH21_05270) | 987647..988651 | + | 1005 | WP_000792163.1 | hypothetical protein | VF |
| EQH21_RS05020 (EQH21_05275) | 988720..989586 | + | 867 | WP_000637234.1 | ABC transporter permease | - |
| EQH21_RS05025 (EQH21_05280) | 989583..990341 | + | 759 | WP_000125400.1 | ABC transporter ATP-binding protein | - |
| EQH21_RS05030 (EQH21_05285) | 990431..992191 | + | 1761 | WP_000227896.1 | DNA primase | - |
| EQH21_RS05035 (EQH21_05290) | 992194..993303 | + | 1110 | WP_000201898.1 | RNA polymerase sigma factor RpoD | - |
| EQH21_RS05040 (EQH21_05295) | 993317..993646 | + | 330 | WP_000331928.1 | metal-sulfur cluster assembly factor | - |
| EQH21_RS05045 (EQH21_05300) | 993761..994804 | + | 1044 | WP_000412279.1 | alpha-galactosylglucosyldiacylglycerol synthase | - |
| EQH21_RS05050 (EQH21_05305) | 994820..996145 | + | 1326 | WP_001219434.1 | glycosyltransferase family 4 protein | - |
| EQH21_RS05055 (EQH21_05310) | 996176..996352 | + | 177 | WP_001256250.1 | PspC domain-containing protein | - |
| EQH21_RS05060 (EQH21_05315) | 996411..996545 | + | 135 | WP_000863859.1 | DUF4044 domain-containing protein | - |
| EQH21_RS05065 (EQH21_05320) | 996609..997919 | + | 1311 | WP_000061646.1 | GTPase ObgE | - |
| EQH21_RS05070 (EQH21_05325) | 997929..998087 | + | 159 | WP_001808548.1 | hypothetical protein | - |
| EQH21_RS05075 (EQH21_05330) | 998139..999465 | - | 1327 | Protein_1011 | ISL3 family transposase | - |
| EQH21_RS05080 (EQH21_05335) | 1000641..1001900 | + | 1260 | WP_001227083.1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | - |
| EQH21_RS05085 (EQH21_05340) | 1001916..1002467 | + | 552 | WP_001103684.1 | GNAT family N-acetyltransferase | - |
| EQH21_RS05090 (EQH21_05345) | 1002460..1003737 | + | 1278 | WP_000033830.1 | CBS-HotDog domain-containing transcription factor SpxR | - |
| EQH21_RS05095 (EQH21_05350) | 1003753..1004613 | + | 861 | WP_000631543.1 | methionyl aminopeptidase | - |
| EQH21_RS05100 (EQH21_05360) | 1004994..1005798 | + | 805 | WP_137997052.1 | IS5 family transposase | - |
| EQH21_RS05105 (EQH21_05365) | 1005990..1008281 | + | 2292 | WP_054362865.1 | DNA helicase PcrA | - |
| EQH21_RS05110 (EQH21_05370) | 1008324..1009004 | + | 681 | WP_000286922.1 | DNA repair protein RadC | - |
| EQH21_RS05115 (EQH21_05375) | 1009001..1009690 | - | 690 | WP_000743316.1 | gamma-glutamyl-gamma-aminobutyrate hydrolase family protein | - |
| EQH21_RS05120 (EQH21_05380) | 1009708..1010349 | - | 642 | WP_000653403.1 | redox-sensing transcriptional repressor Rex | - |
| EQH21_RS05125 (EQH21_05385) | 1010432..1010647 | - | 216 | WP_000462487.1 | DUF4649 family protein | - |
| EQH21_RS05130 (EQH21_05390) | 1010655..1011002 | - | 348 | WP_000863509.1 | DUF1831 domain-containing protein | - |
| EQH21_RS05135 (EQH21_05395) | 1011007..1012122 | - | 1116 | WP_000639664.1 | cysteine desulfurase family protein | - |
| EQH21_RS05140 (EQH21_05400) | 1012132..1013091 | - | 960 | WP_001283813.1 | ribose-phosphate diphosphokinase | - |
| EQH21_RS05145 (EQH21_05405) | 1013204..1013773 | - | 570 | WP_000681292.1 | CYTH domain-containing protein | - |
| EQH21_RS05150 (EQH21_05410) | 1013901..1014572 | + | 672 | WP_000171676.1 | GTP pyrophosphokinase family protein | - |
| EQH21_RS05155 (EQH21_05415) | 1014556..1015374 | + | 819 | WP_000799053.1 | NAD kinase | - |
| EQH21_RS05160 (EQH21_05420) | 1015371..1016267 | + | 897 | WP_001210004.1 | RluA family pseudouridine synthase | - |
| EQH21_RS05165 (EQH21_05425) | 1016311..1017285 | + | 975 | WP_000451586.1 | phosphate acetyltransferase | - |
| EQH21_RS05170 (EQH21_05430) | 1017626..1017925 | - | 300 | WP_000981522.1 | YbaB/EbfC family nucleoid-associated protein | - |
| EQH21_RS05175 (EQH21_05435) | 1018328..1018996 | + | 669 | Protein_1031 | YoaK family protein | - |
| EQH21_RS05180 (EQH21_05440) | 1019268..1020221 | + | 954 | WP_001155321.1 | IS30 family transposase ISSpn8 | Transposase |
| EQH21_RS05185 (EQH21_05450) | 1020460..1020774 | + | 315 | WP_001811359.1 | 50S ribosomal protein L21 | - |
| EQH21_RS05190 (EQH21_05455) | 1020790..1021134 | + | 345 | WP_000613700.1 | ribosomal-processing cysteine protease Prp | - |
| EQH21_RS05195 (EQH21_05460) | 1021151..1021444 | + | 294 | WP_000916509.1 | 50S ribosomal protein L27 | - |
| EQH21_RS05200 (EQH21_05465) | 1021790..1021960 | - | 171 | WP_000123638.1 | hypothetical protein | - |
| EQH21_RS05205 (EQH21_05470) | 1022398..1023315 | + | 918 | WP_000587444.1 | bifunctional riboflavin kinase/FAD synthetase | - |
| EQH21_RS05210 (EQH21_05475) | 1023408..1024256 | - | 849 | WP_000592056.1 | YitT family protein | - |
| EQH21_RS05215 (EQH21_05480) | 1024398..1025237 | + | 840 | WP_000161397.1 | DegV family protein | - |
| EQH21_RS05220 (EQH21_05485) | 1025343..1025618 | + | 276 | WP_001284639.1 | HU family DNA-binding protein | - |
| EQH21_RS05225 (EQH21_05490) | 1026046..1027947 | + | 1902 | WP_000584903.1 | ABC-F family ATP-binding cassette domain-containing protein | - |
| EQH21_RS05230 (EQH21_05495) | 1027950..1028813 | + | 864 | WP_000400550.1 | XRE/MutR family transcriptional regulator | - |
| EQH21_RS05235 (EQH21_05500) | 1028893..1030071 | + | 1179 | WP_001083027.1 | MFS transporter | - |
| EQH21_RS05240 (EQH21_05505) | 1030164..1032122 | + | 1959 | WP_001042587.1 | NAD-dependent DNA ligase LigA | - |
| EQH21_RS05245 (EQH21_05510) | 1032234..1034513 | + | 2280 | WP_000283068.1 | type I pullulanase | - |
| EQH21_RS05250 (EQH21_05515) | 1035057..1036481 | + | 1425 | WP_000199371.1 | NADP-dependent glyceraldehyde-3-phosphate dehydrogenase | - |
| EQH21_RS05255 (EQH21_05525) | 1036964..1038892 | + | 1929 | WP_000370236.1 | 1,4-alpha-glucan branching protein GlgB | - |
| EQH21_RS05260 (EQH21_05530) | 1038882..1040024 | + | 1143 | WP_000787277.1 | glucose-1-phosphate adenylyltransferase | - |
| EQH21_RS05265 (EQH21_05535) | 1040014..1041153 | + | 1140 | WP_000687072.1 | glucose-1-phosphate adenylyltransferase subunit GlgD | - |
| EQH21_RS05270 (EQH21_05540) | 1041150..1042583 | + | 1434 | WP_000697294.1 | glycogen synthase GlgA | - |
| EQH21_RS05275 | 1042702..1043013 | + | 312 | WP_224331470.1 | phosphoserine phosphatase | - |
| EQH21_RS05280 | 1042958..1043287 | + | 330 | WP_001814497.1 | HAD hydrolase family protein | - |
| EQH21_RS05285 (EQH21_05550) | 1043296..1044099 | + | 804 | WP_000706432.1 | glycerate kinase | - |
| EQH21_RS05290 (EQH21_05555) | 1044096..1044542 | - | 447 | WP_000131076.1 | YueI family protein | - |
| EQH21_RS05295 (EQH21_05560) | 1044706..1046010 | + | 1305 | WP_000022815.1 | phosphopyruvate hydratase | - |
| EQH21_RS05300 (EQH21_05565) | 1046344..1047690 | - | 1347 | Protein_1056 | IS1380 family transposase ISSpn5 | Transposase |
| EQH21_RS05305 (EQH21_05570) | 1047856..1048302 | - | 447 | WP_025171968.1 | tyrosine-type recombinase/integrase | - |
| EQH21_RS05310 (EQH21_05575) | 1048202..1049049 | - | 848 | Protein_1058 | IS630 family transposase | - |
| EQH21_RS05315 (EQH21_05585) | 1049220..1049375 | + | 156 | Protein_1059 | diacylglycerol kinase family lipid kinase | - |
| EQH21_RS05320 (EQH21_05590) | 1049575..1052850 | + | 3276 | WP_000772358.1 | ATP-dependent nuclease subunit B | - |
| EQH21_RS05325 (EQH21_05595) | 1052847..1056497 | + | 3651 | WP_000767269.1 | helicase-exonuclease AddAB subunit AddA | - |
| EQH21_RS05330 (EQH21_05600) | 1056712..1057890 | + | 1179 | WP_000174767.1 | hypothetical protein | - |
| EQH21_RS05335 (EQH21_05605) | 1058099..1063882 | + | 5784 | WP_000417142.1 | Immunoglobulin A1 protease | VF |
| EQH21_RS05340 (EQH21_05610) | 1063926..1069301 | + | 5376 | WP_054362867.1 | zinc metalloprotease ZmpD | - |
| EQH21_RS05345 (EQH21_05620) | 1069468..1070814 | + | 1347 | WP_001811769.1 | IS1380 family transposase ISSpn5 | Transposase |
| EQH21_RS05350 (EQH21_05625) | 1070992..1072239 | + | 1248 | WP_000998732.1 | hypothetical protein | - |
| EQH21_RS05355 (EQH21_05630) | 1072271..1073170 | + | 900 | WP_223840796.1 | ABC transporter ATP-binding protein | - |
| EQH21_RS05360 (EQH21_05635) | 1073167..1073967 | + | 801 | WP_000642567.1 | ABC transporter permease | - |
| EQH21_RS05365 (EQH21_05640) | 1074150..1074434 | + | 285 | Protein_1069 | IS200/IS605 family transposase | - |
| EQH21_RS05370 (EQH21_05645) | 1074691..1074914 | + | 224 | Protein_1070 | helix-turn-helix transcriptional regulator | - |
| EQH21_RS05375 (EQH21_05650) | 1075216..1075449 | + | 234 | WP_000404196.1 | hypothetical protein | - |
| EQH21_RS05380 (EQH21_05655) | 1075525..1076991 | + | 1467 | WP_000291914.1 | site-specific integrase | - |
| EQH21_RS05385 (EQH21_05660) | 1077073..1077924 | + | 852 | WP_000201299.1 | ribosome biogenesis GTPase YlqF | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|